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Protein

DNA-directed RNA polymerase subunit N

Gene

rpoN

Organism
Sulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi7ZincBy similarity1
Metal bindingi10ZincBy similarity1
Metal bindingi44ZincBy similarity1
Metal bindingi45ZincBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferase, Transferase
Biological processTranscription
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit N (EC:2.7.7.6)
Gene namesi
Name:rpoN
Ordered Locus Names:SSO5140
OrganismiSulfolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
Taxonomic identifieri273057 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
Proteomesi
  • UP000001974 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001213621 – 66DNA-directed RNA polymerase subunit NAdd BLAST66

Interactioni

Subunit structurei

The S.acidocaldarius RNAP is composed of 13 subunits.

Protein-protein interaction databases

DIPiDIP-60643N
IntActiQ980Z8, 1 interactor
STRINGi273057.SSO5140

Structurei

Secondary structure

166
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliQ980Z8
SMRiQ980Z8
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ980Z8

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiarCOG04244 Archaea
COG1644 LUCA
HOGENOMiHOG000109502
InParanoidiQ980Z8
KOiK03058
OMAiYCCRRMF
OrthoDBiPOG093Z0L4Z

Family and domain databases

HAMAPiMF_00250 RNApol_arch_N, 1 hit
InterProiView protein in InterPro
IPR023580 RNA_pol_su_RPB10
IPR020789 RNA_pol_suN_Zn-BS
IPR000268 RNAP_N/Rpb10
PANTHERiPTHR23431 PTHR23431, 1 hit
PfamiView protein in Pfam
PF01194 RNA_pol_N, 1 hit
PIRSFiPIRSF005653 RNA_pol_N/8_sub, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD006539 RNA_pol_N/8_sub, 1 hit
SUPFAMiSSF46924 SSF46924, 1 hit
PROSITEiView protein in PROSITE
PS01112 RNA_POL_N_8KD, 1 hit

Sequencei

Sequence statusi: Complete.

Q980Z8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLIPIRCFTC GSLIADKWQS FITRVNAGEN PGKVLDDLGV KRYCCRRMLL
60
SHVDIINEVI HYTRPI
Length:66
Mass (Da):7,591
Last modified:August 29, 2001 - v1
Checksum:iC6774B541A1CFA13
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006641 Genomic DNA Translation: AAK40429.1
PIRiF90146
RefSeqiWP_009988875.1, NC_002754.1

Genome annotation databases

EnsemblBacteriaiAAK40429; AAK40429; SSO5140
GeneIDi27426363
KEGGisso:SSO5140
PATRICifig|273057.12.peg.68

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006641 Genomic DNA Translation: AAK40429.1
PIRiF90146
RefSeqiWP_009988875.1, NC_002754.1

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2PMZX-ray3.40N/Y1-66[»]
3HKZX-ray3.40N/W1-66[»]
ProteinModelPortaliQ980Z8
SMRiQ980Z8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-60643N
IntActiQ980Z8, 1 interactor
STRINGi273057.SSO5140

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAK40429; AAK40429; SSO5140
GeneIDi27426363
KEGGisso:SSO5140
PATRICifig|273057.12.peg.68

Phylogenomic databases

eggNOGiarCOG04244 Archaea
COG1644 LUCA
HOGENOMiHOG000109502
InParanoidiQ980Z8
KOiK03058
OMAiYCCRRMF
OrthoDBiPOG093Z0L4Z

Miscellaneous databases

EvolutionaryTraceiQ980Z8

Family and domain databases

HAMAPiMF_00250 RNApol_arch_N, 1 hit
InterProiView protein in InterPro
IPR023580 RNA_pol_su_RPB10
IPR020789 RNA_pol_suN_Zn-BS
IPR000268 RNAP_N/Rpb10
PANTHERiPTHR23431 PTHR23431, 1 hit
PfamiView protein in Pfam
PF01194 RNA_pol_N, 1 hit
PIRSFiPIRSF005653 RNA_pol_N/8_sub, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD006539 RNA_pol_N/8_sub, 1 hit
SUPFAMiSSF46924 SSF46924, 1 hit
PROSITEiView protein in PROSITE
PS01112 RNA_POL_N_8KD, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRPON_SULSO
AccessioniPrimary (citable) accession number: Q980Z8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 29, 2001
Last sequence update: August 29, 2001
Last modified: October 10, 2018
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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Main funding by: National Institutes of Health

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