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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:CA_C1041
OrganismiClostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
Taxonomic identifieri272562 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
Proteomesi
  • UP000000814 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001515501 – 563Arginine--tRNA ligaseAdd BLAST563

Proteomic databases

PRIDEiQ97K78

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi272562.CA_C1041

Structurei

3D structure databases

ProteinModelPortaliQ97K78
SMRiQ97K78
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi120 – 130"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247211
KOiK01887
OMAiNKPLHLG

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

Q97K78-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDYKKVIAER INKIVDMDVE ALYKIIEIPP KKDMGDFALP CFQFAKVLRK
60 70 80 90 100
APNAIAEEVC KKIDQSGFEK VENLGPYINF FVDKADFAKE TIESVLSERD
110 120 130 140 150
NYGRSKVGEG KKVLIEYSSP NIAKPFHVGH LFGTVLGSSL YKIFSMEGYD
160 170 180 190 200
CVRINHLGDW GTQFGKLISA YKRWCDEDAL YKDPIKELLR IYVKFHKEAE
210 220 230 240 250
KDPLLEDEGR MYFKRLEDGE KEEVELWTKF KDLSLREFKK VYNQIGVEFD
260 270 280 290 300
SYTGESFYSD KIDAIEEELN EKGLLTESNG AKVVMLDEYN MPPCIIKKAD
310 320 330 340 350
GASIYATRDL AAAEYRKKTY NFDKSIYVVG LEQSLHFKQF LKTLELAGHE
360 370 380 390 400
WSKDCIHVGY GLVRFAEGKL STRNGDVIFL EDLLKESVQK TSEIIEEKNP
410 420 430 440 450
ELDNKEEVSR KVGIGAVIFT YLKNGRERDI IFDWKEMLSF EGETGPYVQY
460 470 480 490 500
SYARAKSILR KLGEVKGNVS YDKLVSAEEF DLIKQLKGFN GAILNAIDRL
510 520 530 540 550
EPSVITRYVI EVAKAFNKFY NAYNISNTSD EELKNARLAL VEAASIVIKN
560
ALSLIGIDVV EEM
Length:563
Mass (Da):64,392
Last modified:October 1, 2001 - v1
Checksum:i0BE96F3464904E21
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001437 Genomic DNA Translation: AAK79017.1
PIRiF97028
RefSeqiNP_347677.1, NC_003030.1
WP_010964359.1, NC_003030.1

Genome annotation databases

EnsemblBacteriaiAAK79017; AAK79017; CA_C1041
GeneIDi1117224
KEGGicac:CA_C1041
PATRICifig|272562.8.peg.1249

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE001437 Genomic DNA Translation: AAK79017.1
PIRiF97028
RefSeqiNP_347677.1, NC_003030.1
WP_010964359.1, NC_003030.1

3D structure databases

ProteinModelPortaliQ97K78
SMRiQ97K78
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272562.CA_C1041

Proteomic databases

PRIDEiQ97K78

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAK79017; AAK79017; CA_C1041
GeneIDi1117224
KEGGicac:CA_C1041
PATRICifig|272562.8.peg.1249

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247211
KOiK01887
OMAiNKPLHLG

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiSYR_CLOAB
AccessioniPrimary (citable) accession number: Q97K78
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 10, 2002
Last sequence update: October 1, 2001
Last modified: October 10, 2018
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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