UniProtKB - Q97GT8 (Q97GT8_CLOAB)
Protein
Protein-export membrane protein SecF
Gene
secF
Organism
Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
Status
Functioni
Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.UniRule annotation
Caution
Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation
GO - Molecular functioni
GO - Biological processi
- intracellular protein transmembrane transport Source: UniProtKB-UniRule
- protein targeting Source: UniProtKB-UniRule
- protein transport by the Sec complex Source: UniProtKB-UniRule
Keywordsi
Biological process | Protein transport, TranslocationUniRule annotationARBA annotation, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Protein-export membrane protein SecFUniRule annotation |
Gene namesi | Name:secFUniRule annotationImported Ordered Locus Names:CA_C2277Imported |
Organismi | Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)Imported |
Taxonomic identifieri | 272562 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium › |
Proteomesi |
|
Subcellular locationi
- Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 12 – 31 | HelicalUniRule annotationAdd BLAST | 20 | |
Transmembranei | 131 – 148 | HelicalUniRule annotationAdd BLAST | 18 | |
Transmembranei | 234 – 255 | HelicalUniRule annotationAdd BLAST | 22 | |
Transmembranei | 261 – 283 | HelicalUniRule annotationAdd BLAST | 23 |
GO - Cellular componenti
- integral component of membrane Source: UniProtKB-KW
- plasma membrane Source: UniProtKB-SubCell
Keywords - Cellular componenti
Cell membraneUniRule annotationARBA annotation, MembraneInteractioni
Subunit structurei
Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
UniRule annotationProtein-protein interaction databases
STRINGi | 272562.CA_C2277 |
Family & Domainsi
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixUniRule annotationARBA annotationPhylogenomic databases
eggNOGi | COG0341, Bacteria |
HOGENOMi | CLU_050012_0_0_9 |
OMAi | AFEWRMA |
OrthoDBi | 410730at2 |
Family and domain databases
HAMAPi | MF_01464_B, SecF_B, 1 hit |
InterProi | View protein in InterPro IPR022813, SecD/SecF_arch_bac IPR022645, SecD/SecF_bac IPR005665, SecF_bac |
PANTHERi | PTHR30081, PTHR30081, 1 hit |
Pfami | View protein in Pfam PF02355, SecD_SecF, 1 hit |
PRINTSi | PR01755, SECFTRNLCASE |
TIGRFAMsi | TIGR00916, 2A0604s01, 1 hit TIGR00966, 3a0501s07, 1 hit |
i Sequence
Sequence statusi: Complete.
Q97GT8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLKVIKHTKV WFGISLTIIF LGIAFMIYRG VTTGKPLEFG IDFVGGNSMD
60 70 80 90 100
IKIGKSFNKT DVEKIVDKYI KDSTITTVNN TEVEIKSSTM TDAIGNKIFK
110 120 130 140 150
DMQKKYNLKS KALVSQEKIG GTIGQELKTK ALIALAIALV IILLYIAWRF
160 170 180 190 200
EFKFGVAAMI SLVHDVLVTL AVYGIFAIPL NSPFIAGMLT IVGYSMSDTI
210 220 230 240 250
VVFDRIRENS RKHRRMSTSE IADFSINETL TRSIYTVLTV LIAVSSVHVF
260 270 280 290 300
VPSVRDFTKP LLVGIVSGCY SSIFIASPLW VIFKERANKK KLQIKAEAQK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE001437 Genomic DNA Translation: AAK80234.1 |
PIRi | G97180 |
RefSeqi | NP_348894.1, NC_003030.1 WP_010965575.1, NC_003030.1 |
Genome annotation databases
EnsemblBacteriai | AAK80234; AAK80234; CA_C2277 |
GeneIDi | 44998754 |
KEGGi | cac:CA_C2277 |
PATRICi | fig|272562.8.peg.2475 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE001437 Genomic DNA Translation: AAK80234.1 |
PIRi | G97180 |
RefSeqi | NP_348894.1, NC_003030.1 WP_010965575.1, NC_003030.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 272562.CA_C2277 |
Genome annotation databases
EnsemblBacteriai | AAK80234; AAK80234; CA_C2277 |
GeneIDi | 44998754 |
KEGGi | cac:CA_C2277 |
PATRICi | fig|272562.8.peg.2475 |
Phylogenomic databases
eggNOGi | COG0341, Bacteria |
HOGENOMi | CLU_050012_0_0_9 |
OMAi | AFEWRMA |
OrthoDBi | 410730at2 |
Family and domain databases
HAMAPi | MF_01464_B, SecF_B, 1 hit |
InterProi | View protein in InterPro IPR022813, SecD/SecF_arch_bac IPR022645, SecD/SecF_bac IPR005665, SecF_bac |
PANTHERi | PTHR30081, PTHR30081, 1 hit |
Pfami | View protein in Pfam PF02355, SecD_SecF, 1 hit |
PRINTSi | PR01755, SECFTRNLCASE |
TIGRFAMsi | TIGR00916, 2A0604s01, 1 hit TIGR00966, 3a0501s07, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q97GT8_CLOAB | |
Accessioni | Q97GT8Primary (citable) accession number: Q97GT8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 1, 2001 |
Last sequence update: | October 1, 2001 | |
Last modified: | December 2, 2020 | |
This is version 104 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |