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Protein

Replication factor C small subunit

Gene

rfcS

Organism
Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi43 – 50ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processDNA replication
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciTVOL273116:G1G3C-1623-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Replication factor C small subunitUniRule annotation
Short name:
RFC small subunitUniRule annotation
Alternative name(s):
Clamp loader small subunitUniRule annotation
Gene namesi
Name:rfcSUniRule annotation
Ordered Locus Names:TV1518
ORF Names:TVG1570739
OrganismiThermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)
Taxonomic identifieri273116 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaDiaforarchaea groupThermoplasmataThermoplasmatalesThermoplasmataceaeThermoplasma
Proteomesi
  • UP000001017 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001359871 – 318Replication factor C small subunitAdd BLAST318

Proteomic databases

PRIDEiQ977Z9

Interactioni

Subunit structurei

Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).UniRule annotation

Protein-protein interaction databases

STRINGi273116.TVN1491

Structurei

3D structure databases

ProteinModelPortaliQ977Z9
SMRiQ977Z9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the activator 1 small subunits family. RfcS subfamily.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00469 Archaea
COG0470 LUCA
KOiK04801
OMAiQSTWSGF
OrthoDBiPOG093Z05CK

Family and domain databases

HAMAPiMF_01509 RfcS, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR003959 ATPase_AAA_core
IPR008921 DNA_pol3_clamp-load_cplx_C
IPR027417 P-loop_NTPase
IPR023748 Rep_factor-C_ssu_arc
IPR013748 Rep_factorC_C
PfamiView protein in Pfam
PF00004 AAA, 1 hit
PF08542 Rep_fac_C, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF48019 SSF48019, 1 hit
SSF52540 SSF52540, 1 hit

Sequencei

Sequence statusi: Complete.

Q977Z9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIEIWTEKYR PKSLSEIYGE DENIQKLKSF VEKKELPHLL FAGSVGTGKT
60 70 80 90 100
STAIALAIEL FGESWKENFI EMNASNENGI DVIRNKIKDI ARIRPSNPLG
110 120 130 140 150
FKILFLDEAD QLTAEAQAAL RRTMEMYSET TRFVFACNYS SKIIPPIQSR
160 170 180 190 200
TVVMRFRPVQ DEFIKKKLNE IAKNEGFTID DESMEAMVEV SGGDMRKAIN
210 220 230 240 250
VLQAVYTSGE ISPKKIYEII GYASPESVNK LISRAINGLF DEARQIVDKM
260 270 280 290 300
MIEDGLSGID IVKSVHSIVR ASVVPPKQKI EIIKALADAE FRIVEGSNDR
310
IQLDALIARI ADIGSKIN
Length:318
Mass (Da):35,666
Last modified:August 30, 2005 - v2
Checksum:i41BE7007C87E0884
GO

Sequence cautioni

The sequence BAB60660 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000011 Genomic DNA Translation: BAB60660.1 Different initiation.
RefSeqiWP_010917747.1, NC_002689.2

Genome annotation databases

EnsemblBacteriaiBAB60660; BAB60660; BAB60660
GeneIDi1442207
KEGGitvo:TVG1570739

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000011 Genomic DNA Translation: BAB60660.1 Different initiation.
RefSeqiWP_010917747.1, NC_002689.2

3D structure databases

ProteinModelPortaliQ977Z9
SMRiQ977Z9
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi273116.TVN1491

Proteomic databases

PRIDEiQ977Z9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAB60660; BAB60660; BAB60660
GeneIDi1442207
KEGGitvo:TVG1570739

Phylogenomic databases

eggNOGiarCOG00469 Archaea
COG0470 LUCA
KOiK04801
OMAiQSTWSGF
OrthoDBiPOG093Z05CK

Enzyme and pathway databases

BioCyciTVOL273116:G1G3C-1623-MONOMER

Family and domain databases

HAMAPiMF_01509 RfcS, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR003959 ATPase_AAA_core
IPR008921 DNA_pol3_clamp-load_cplx_C
IPR027417 P-loop_NTPase
IPR023748 Rep_factor-C_ssu_arc
IPR013748 Rep_factorC_C
PfamiView protein in Pfam
PF00004 AAA, 1 hit
PF08542 Rep_fac_C, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF48019 SSF48019, 1 hit
SSF52540 SSF52540, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRFCS_THEVO
AccessioniPrimary (citable) accession number: Q977Z9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 16, 2004
Last sequence update: August 30, 2005
Last modified: November 7, 2018
This is version 85 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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