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Entry version 98 (31 Jul 2019)
Sequence version 1 (01 Dec 2001)
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Protein
Submitted name:

ABC transporter protein

Gene

atrG

Organism
Emericella nidulans (Aspergillus nidulans)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi911 – 918ATPPROSITE-ProRule annotation8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processTransportSAAS annotation
LigandATP-bindingPROSITE-ProRule annotationSAAS annotation, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
ABC transporter proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:atrGImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEmericella nidulans (Aspergillus nidulans)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri162425 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei539 – 559HelicalSequence analysisAdd BLAST21
Transmembranei571 – 596HelicalSequence analysisAdd BLAST26
Transmembranei662 – 683HelicalSequence analysisAdd BLAST22
Transmembranei695 – 714HelicalSequence analysisAdd BLAST20
Transmembranei798 – 818HelicalSequence analysisAdd BLAST21
Transmembranei1213 – 1234HelicalSequence analysisAdd BLAST22
Transmembranei1246 – 1269HelicalSequence analysisAdd BLAST24
Transmembranei1290 – 1316HelicalSequence analysisAdd BLAST27
Transmembranei1336 – 1358HelicalSequence analysisAdd BLAST23
Transmembranei1370 – 1394HelicalSequence analysisAdd BLAST25
Transmembranei1489 – 1507HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini172 – 426ABC transporterInterPro annotationAdd BLAST255
Domaini875 – 1118ABC transporterInterPro annotationAdd BLAST244

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 79DisorderedSequence analysisAdd BLAST79
Regioni842 – 862DisorderedSequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 37PolarSequence analysisAdd BLAST37
Compositional biasi47 – 62PolarSequence analysisAdd BLAST16
Compositional biasi63 – 79PolyampholyteSequence analysisAdd BLAST17
Compositional biasi843 – 862PolarSequence analysisAdd BLAST20

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily. [View classification]SAAS annotation

Keywords - Domaini

RepeatSAAS annotation, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0065 Eukaryota
COG0842 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000162078

Family and domain databases

Conserved Domains Database

More...
CDDi
cd03233 ABCG_PDR_domain1, 1 hit
cd03232 ABCG_PDR_domain2, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003593 AAA+_ATPase
IPR013525 ABC_2_trans
IPR029481 ABC_trans_N
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR034001 ABCG_PDR_1
IPR034003 ABCG_PDR_2
IPR027417 P-loop_NTPase
IPR010929 PDR_CDR_ABC

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01061 ABC2_membrane, 2 hits
PF00005 ABC_tran, 2 hits
PF14510 ABC_trans_N, 1 hit
PF06422 PDR_CDR, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00382 AAA, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q96VK4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSFLGTGTF NTSVSPSQAV ESRGIENHGN AITETETLHN ESHAESPGEK
60 70 80 90 100
LASSSNSILS STETAREKDE RDYELDAEEE VTRLAQQLTH QSTKYSTHNI
110 120 130 140 150
ENPFLEVGED STLNPHSPNF KAKNWMKNLL ALSSRDPERY LPRQAGVSFT
160 170 180 190 200
NLSVHGYGSP TDYQKDVFNS VLQIGGLVRS MMGHGKQKIE ILRNFDGLVK
210 220 230 240 250
AGEMLVVLGR PGSGCSTFLK TIAGEMNGIF MDEKSQLNYQ GIPAKQMRKQ
260 270 280 290 300
FRGEAIYTAE TDVHFPQLSV GDTLKFAALA RCPRNRLPGV SREQYAVHMR
310 320 330 340 350
DVVMAMLGLS HTINTRVGND FVRGVSGGER KRVSIAEATL SASPLQCWDN
360 370 380 390 400
STRGLDSANA LEFCRTLNLM AKYSGATMAV AIYQASQSAY DVFDKVTVLY
410 420 430 440 450
EGRQIYFGRT DDAKQFFIDM GFECPERQTT ADFLTSLTSP AERIVRKGYE
460 470 480 490 500
GRVPQTPDEF AAAWKNSDAY AQLMREIEEY NQEFPLGGES VNKFIESRRA
510 520 530 540 550
MQSKNQRVKS PYTMSVMEQV HLCMIRGFQR LKGDASLTLS QLIGNFIMAL
560 570 580 590 600
VIGSVFYDLD NDTGSFYSRG ALLFFAVLLN AFGSALEVCL ILRLFLSLAD
610 620 630 640 650
SLQILTLYAQ RPIVEKQARY AMYHPFAEAI ASMLCDMPYK ITNTFTFNIP
660 670 680 690 700
LYFMTNLRRE PGAFFIFLLF SFVTTLTMSM LFRTMAATSR TLSQALVPAA
710 720 730 740 750
ILILGLVIYT GFTIPTRNML GWSRWMNYID PIAYGFESLM VNEFHGRLFP
760 770 780 790 800
CSESELVPSY GDTANRVCAV VGATPGELMV NGTTYLRESY QYTKSHEWRN
810 820 830 840 850
LGIMFAFMAF FLFTYLTATE YISEAKSKGE VLLFRRGQAP PSVNDVETHS
860 870 880 890 900
PATAGEKVDQ STQDVANIQR QTAIFHWKDV CYDIKIKNEP RRILDHVDGW
910 920 930 940 950
VKPGTCTALM GVSGAGKTTL LDVLATRVTM GVVTGEMLVD GRPRDQSFQR
960 970 980 990 1000
KTGYVQQQDL HLHTTTVREA LRFSALLRQP AKTPRQEKLD YVEEVIKLLG
1010 1020 1030 1040 1050
MEAYADAVVG VPGEGLNVEQ RKRLTIGVEL AAKPQLLLFL DEPTSGLDSQ
1060 1070 1080 1090 1100
TSWSILDLID TLTQHGQAIL CTIHQPSAML FQRFDRLLFL AKGGKTVYFG
1110 1120 1130 1140 1150
EIGEKSSTLA SYFERNGAPK LPADANPAEW MLEVIGAAPG SHSDIDWPAV
1160 1170 1180 1190 1200
WRESPERQAV HQHLAELKET LSQKPTETSA SDPSEYNEFA APFSVQLWEC
1210 1220 1230 1240 1250
LVRVFSQYWR SPVYIYSKAA LSILTSLYIG FSFFQAQNTR QGLQNQMFSI
1260 1270 1280 1290 1300
FMLMTIFGNL VQQIMPNFVT QRALYEVRER PSKAYSWKAF MTANILVELP
1310 1320 1330 1340 1350
WNTLMAVIMY FCWYYPVGLY RNAEPTDSVH ERGALMFLLI LAFLLFTSTF
1360 1370 1380 1390 1400
AHMIIAGIET AETGGNIAQL LFSLCLIFCG VLAGPDVLPG FWIFMYRVSP
1410 1420 1430 1440 1450
FTYLVSAMLS TGVSGTTAYC EQVEYLTLYP PSNTTCSEYM DPYISQVGGY
1460 1470 1480 1490 1500
LQNPDATSEC TFCQISSTDT FLSAVYSNYD DAWRNFGLMW AYIAFNIAAA
1510
VFIYWLARVP KGKKN
Length:1,515
Mass (Da):169,781
Last modified:December 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0CAD94A20B3505D8
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AJ309282 Genomic DNA Translation: CAC42218.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ309282 Genomic DNA Translation: CAC42218.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG0065 Eukaryota
COG0842 LUCA
HOGENOMiHOG000162078

Family and domain databases

CDDicd03233 ABCG_PDR_domain1, 1 hit
cd03232 ABCG_PDR_domain2, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR013525 ABC_2_trans
IPR029481 ABC_trans_N
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR034001 ABCG_PDR_1
IPR034003 ABCG_PDR_2
IPR027417 P-loop_NTPase
IPR010929 PDR_CDR_ABC
PfamiView protein in Pfam
PF01061 ABC2_membrane, 2 hits
PF00005 ABC_tran, 2 hits
PF14510 ABC_trans_N, 1 hit
PF06422 PDR_CDR, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 2 hits
SUPFAMiSSF52540 SSF52540, 2 hits
PROSITEiView protein in PROSITE
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ96VK4_EMEND
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96VK4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: July 31, 2019
This is version 98 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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