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Protein

Glutamine synthetase

Gene

glnA

Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine synthetase (EC:6.3.1.2)
Short name:
GS
Alternative name(s):
Glutamate--ammonia ligase
Gene namesi
Name:glnA
ORF Names:AN4159
OrganismiEmericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Taxonomic identifieri227321 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000000560 Componenti: Chromosome II
  • UP000005890 Componenti: Unassembled WGS sequence

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001531561 – 357Glutamine synthetaseAdd BLAST357

Interactioni

Subunit structurei

Homooctamer.By similarity

Protein-protein interaction databases

STRINGi162425.CADANIAP00004514

Structurei

3D structure databases

SMRiQ96V52
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutamine synthetase family.Curated

Phylogenomic databases

HOGENOMiHOG000061500
InParanoidiQ96V52
KOiK01915
OMAiMMPDGVT
OrthoDBiEOG092C2OM1

Family and domain databases

Gene3Di3.10.20.70, 1 hit
InterProiView protein in InterPro
IPR008147 Gln_synt_b-grasp
IPR036651 Gln_synt_N
IPR014746 Gln_synth/guanido_kin_cat_dom
IPR008146 Gln_synth_cat_dom
IPR027303 Gln_synth_gly_rich_site
IPR027302 Gln_synth_N_conserv_site
PfamiView protein in Pfam
PF00120 Gln-synt_C, 1 hit
PF03951 Gln-synt_N, 1 hit
SMARTiView protein in SMART
SM01230 Gln-synt_C, 1 hit
SUPFAMiSSF54368 SSF54368, 1 hit
SSF55931 SSF55931, 1 hit
PROSITEiView protein in PROSITE
PS00180 GLNA_1, 1 hit
PS00181 GLNA_ATP, 1 hit

Sequencei

Sequence statusi: Complete.

Q96V52-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTDSTNVSNT ENLMKYMSLD QRGSVMAEYI WIDAHGGTRS KTKTLSKAPS
60 70 80 90 100
SVDELPEWNF DGSSTAQAPG DNSDVYLRPV AMYPDPFRRG DNILVLCETW
110 120 130 140 150
DSDGSPNKFN YRHDCARLME THAKEEFWFG LEQEYTLLGP DGWPYGWPKG
160 170 180 190 200
GFPGAQGPYY CGVGTGKVYC RDIVEAHYRA CLYAGVKISG INAEVMPSQW
210 220 230 240 250
EYQVGPCHGI EMGDHLWISR FLLHRVAEEF GVKISFDPKP IKGDWNGAGL
260 270 280 290 300
HTNVSTTSTR AEGGIKAIES YMKKLEARHV EHIAVYGEGN EERLTGRHET
310 320 330 340 350
GNIDKFSYGV ADRGGSIRIP RQVAKDGKGY FEDRRPASNA DPYQITGIIA

ETLCGGL
Length:357
Mass (Da):39,714
Last modified:November 16, 2011 - v3
Checksum:i3A8D1110050EE9CA
GO

Sequence cautioni

The sequence AAK70354 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence EAA59420 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti236F → N in AAK70354 (PubMed:11566979).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF333968 Genomic DNA Translation: AAK70354.1 Sequence problems.
AACD01000067 Genomic DNA Translation: EAA59420.1 Sequence problems.
BN001302 Genomic DNA Translation: CBF74586.1
RefSeqiXP_661763.1, XM_656671.1

Genome annotation databases

EnsemblFungiiCBF74586; CBF74586; ANIA_04159
EAA59420; EAA59420; AN4159.2
GeneIDi2873585
KEGGiani:AN4159.2

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF333968 Genomic DNA Translation: AAK70354.1 Sequence problems.
AACD01000067 Genomic DNA Translation: EAA59420.1 Sequence problems.
BN001302 Genomic DNA Translation: CBF74586.1
RefSeqiXP_661763.1, XM_656671.1

3D structure databases

SMRiQ96V52
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi162425.CADANIAP00004514

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCBF74586; CBF74586; ANIA_04159
EAA59420; EAA59420; AN4159.2
GeneIDi2873585
KEGGiani:AN4159.2

Phylogenomic databases

HOGENOMiHOG000061500
InParanoidiQ96V52
KOiK01915
OMAiMMPDGVT
OrthoDBiEOG092C2OM1

Family and domain databases

Gene3Di3.10.20.70, 1 hit
InterProiView protein in InterPro
IPR008147 Gln_synt_b-grasp
IPR036651 Gln_synt_N
IPR014746 Gln_synth/guanido_kin_cat_dom
IPR008146 Gln_synth_cat_dom
IPR027303 Gln_synth_gly_rich_site
IPR027302 Gln_synth_N_conserv_site
PfamiView protein in Pfam
PF00120 Gln-synt_C, 1 hit
PF03951 Gln-synt_N, 1 hit
SMARTiView protein in SMART
SM01230 Gln-synt_C, 1 hit
SUPFAMiSSF54368 SSF54368, 1 hit
SSF55931 SSF55931, 1 hit
PROSITEiView protein in PROSITE
PS00180 GLNA_1, 1 hit
PS00181 GLNA_ATP, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiGLNA_EMENI
AccessioniPrimary (citable) accession number: Q96V52
Secondary accession number(s): C8V4Q5, Q5B5M1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: November 16, 2011
Last modified: June 20, 2018
This is version 89 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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