UniProtKB - Q96SQ9 (CP2S1_HUMAN)

BLAST

>sp|Q96SQ9|CP2S1_HUMAN Cytochrome P450 2S1 OS=Homo sapiens OX=9606 GN=CYP2S1 PE=1 SV=2
MEATGTWALLLALALLLLLTLALSGTRARGHLPPGPTPLPLLGNLLQLRPGALYSGLMRL
SKKYGPVFTIYLGPWRPVVVLVGQEAVREALGGQAEEFSGRGTVAMLEGTFDGHGVFFSN
GERWRQLRKFTMLALRDLGMGKREGEELIQAEARCLVETFQGTEGRPFDPSLLLAQATSN
VVCSLLFGLRFSYEDKEFQAVVRAAGGTLLGVSSQGGQTYEMFSWFLRPLPGPHKQLLHH
VSTLAAFTVRQVQQHQGNLDASGPARDLVDAFLLKMAQEEQNPGTEFTNKNMLMTVIYLL
FAGTMTVSTTVGYTLLLLMKYPHVQKWVREELNRELGAGQAPSLGDRTRLPYTDAVLHEA
QRLLALVPMGIPRTLMRTTRFRGYTLPQGTEVFPLLGSILHDPNIFKHPEEFNPDRFLDA
DGRFRKHEAFLPFSLGKRVCLGEGLAKAELFLFFTTILQAFSLESPCPPDTLSLKPTVSG
LFNIPPAFQLQVRPTDLHSTTQTR

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History
Entry version 148 (07 Nov 2018)
Sequence version 2 (07 Jun 2004)
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Protein

Cytochrome P450 2S1

Gene

CYP2S1

Organism

Homo sapiens (Human)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

Has a potential importance for extrahepatic xenobiotic metabolism.

Catalytic activityⁱ

RH + [reduced NADPH--hemoprotein reductase] + O₂ = ROH + [oxidized NADPH--hemoprotein reductase] + H₂O.

Cofactorⁱ

hemeBy similarity

Sites

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Metal bindingⁱ	440	Iron (heme axial ligand)By similarity		1

GO - Molecular functionⁱ

arachidonic acid epoxygenase activity
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
aromatase activity Source: UniProtKB-EC
heme binding
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
iron ion binding Source: InterPro
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
retinoic acid 4-hydroxylase activity Source: Reactome
steroid hydroxylase activity
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

epoxygenase P450 pathway
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
exogenous drug catabolic process
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
organic acid metabolic process
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
oxidation-reduction process
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
xenobiotic metabolic process
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Monooxygenase, Oxidoreductase
Ligand	Heme, Iron, Metal-binding

Enzyme and pathway databases

Reactomeⁱ	R-HSA-211958 Miscellaneous substrates R-HSA-211981 Xenobiotics R-HSA-211999 CYP2E1 reactions

Reactomeⁱ

R-HSA-211958 Miscellaneous substrates
R-HSA-211981 Xenobiotics
R-HSA-211999 CYP2E1 reactions

Chemistry databases

SwissLipidsⁱ	SLP:000001465

SwissLipidsⁱ

SLP:000001465

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Cytochrome P450 2S1 (EC:1.14.14.1) Alternative name(s): CYPIIS1
Gene namesⁱ	Name:CYP2S1 ORF Names:UNQ891/PRO1906
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 19

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000167600.13
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:15654 CYP2S1
MIMⁱ	611529 gene
neXtProtⁱ	NX_Q96SQ9

Keywords - Cellular componentⁱ

Endoplasmic reticulum, Membrane, Microsome

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	29785
Open Targets More...OpenTargetsⁱ	ENSG00000167600
PharmGKBⁱ	PA27113

Polymorphism and mutation databases

BioMutaⁱ	CYP2S1
DMDMⁱ	48428134

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000051780	1 – 504	Cytochrome P450 2S1Add BLAST		504

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q96SQ9
PaxDbⁱ	Q96SQ9
PeptideAtlas More...PeptideAtlasⁱ	Q96SQ9
PRIDEⁱ	Q96SQ9
ProteomicsDBⁱ	78138 78139 [Q96SQ9-2]

PTM databases

iPTMnetⁱ	Q96SQ9
PhosphoSitePlusⁱ	Q96SQ9

Expressionⁱ

Tissue specificityⁱ

High level of expression in trachea, lung, stomach, small intestine, and spleen.1 Publication

Gene expression databases

Bgeeⁱ	ENSG00000167600 Expressed in 111 organ(s), highest expression level in jejunal mucosa
CleanExⁱ	HS_CYP2S1
ExpressionAtlasⁱ	Q96SQ9 baseline and differential
Genevisibleⁱ	Q96SQ9 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA049227 HPA069248

HPAⁱ

HPA049227
HPA069248

Interactionⁱ

Binary interactionsⁱ

With	Entry	#Exp.	IntAct	Notes
ADAMTSL4	Q6UY14-3	3	EBI-8633740,EBI-10173507

With

Entry

#Exp.

IntAct

Notes

ADAMTSL4

Q6UY14-3

EBI-8633740,EBI-10173507

Protein-protein interaction databases

BioGridⁱ	118915, 38 interactors
IntActⁱ	Q96SQ9, 3 interactors
Molecular INTeraction database More...MINTⁱ	Q96SQ9
STRINGⁱ	9606.ENSP00000308032

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q96SQ9
SMRⁱ	Q96SQ9
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the cytochrome P450 family.Curated

Phylogenomic databases

eggNOGⁱ	KOG0156 Eukaryota COG2124 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00900000140831
HOGENOMⁱ	HOG000036992
HOVERGENⁱ	HBG015789
InParanoidⁱ	Q96SQ9
KEGG Orthology (KO) More...KOⁱ	K07420
OMAⁱ	KFTMLAL
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0BT8
PhylomeDBⁱ	Q96SQ9
TreeFamⁱ	TF352043

Family and domain databases

Gene3Dⁱ	1.10.630.10, 1 hit
InterProⁱ	View protein in InterPro IPR001128 Cyt_P450 IPR017972 Cyt_P450_CS IPR002401 Cyt_P450_E_grp-I IPR008067 Cyt_P450_E_grp-I_CYP2A-like IPR036396 Cyt_P450_sf
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00067 p450, 1 hit
PRINTSⁱ	PR00463 EP450I PR01684 EP450ICYP2A PR00385 P450
SUPFAMⁱ	SSF48264 SSF48264, 1 hit
PROSITEⁱ	View protein in PROSITE PS00086 CYTOCHROME_P450, 1 hit

Sequences (2+)ⁱ

Sequence statusⁱ: Complete.

This entry describes 2 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 2 described isoforms and 5 potential isoforms that are computationally mapped.Show all Align All

Isoform 1 (identifier: Q96SQ9-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MEATGTWALL LALALLLLLT LALSGTRARG HLPPGPTPLP LLGNLLQLRP 
        60         70         80         90        100
GALYSGLMRL SKKYGPVFTI YLGPWRPVVV LVGQEAVREA LGGQAEEFSG 
       110        120        130        140        150
RGTVAMLEGT FDGHGVFFSN GERWRQLRKF TMLALRDLGM GKREGEELIQ 
       160        170        180        190        200
AEARCLVETF QGTEGRPFDP SLLLAQATSN VVCSLLFGLR FSYEDKEFQA 
       210        220        230        240        250
VVRAAGGTLL GVSSQGGQTY EMFSWFLRPL PGPHKQLLHH VSTLAAFTVR 
       260        270        280        290        300
QVQQHQGNLD ASGPARDLVD AFLLKMAQEE QNPGTEFTNK NMLMTVIYLL 
       310        320        330        340        350
FAGTMTVSTT VGYTLLLLMK YPHVQKWVRE ELNRELGAGQ APSLGDRTRL 
       360        370        380        390        400
PYTDAVLHEA QRLLALVPMG IPRTLMRTTR FRGYTLPQGT EVFPLLGSIL 
       410        420        430        440        450
HDPNIFKHPE EFNPDRFLDA DGRFRKHEAF LPFSLGKRVC LGEGLAKAEL 
       460        470        480        490        500
FLFFTTILQA FSLESPCPPD TLSLKPTVSG LFNIPPAFQL QVRPTDLHST 

TQTR

Length:504

Mass (Da):55,817

Last modified:June 7, 2004 - v2

Checksum:ⁱ853513370F65E25A

Isoform 2 (identifier: Q96SQ9-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
488-504: FQLQVRPTDLHSTTQTR → STVGMDRVNV...KYSPSAITST

« Hide

        10         20         30         40         50
MEATGTWALL LALALLLLLT LALSGTRARG HLPPGPTPLP LLGNLLQLRP 
        60         70         80         90        100
GALYSGLMRL SKKYGPVFTI YLGPWRPVVV LVGQEAVREA LGGQAEEFSG 
       110        120        130        140        150
RGTVAMLEGT FDGHGVFFSN GERWRQLRKF TMLALRDLGM GKREGEELIQ 
       160        170        180        190        200
AEARCLVETF QGTEGRPFDP SLLLAQATSN VVCSLLFGLR FSYEDKEFQA 
       210        220        230        240        250
VVRAAGGTLL GVSSQGGQTY EMFSWFLRPL PGPHKQLLHH VSTLAAFTVR 
       260        270        280        290        300
QVQQHQGNLD ASGPARDLVD AFLLKMAQEE QNPGTEFTNK NMLMTVIYLL 
       310        320        330        340        350
FAGTMTVSTT VGYTLLLLMK YPHVQKWVRE ELNRELGAGQ APSLGDRTRL 
       360        370        380        390        400
PYTDAVLHEA QRLLALVPMG IPRTLMRTTR FRGYTLPQGT EVFPLLGSIL 
       410        420        430        440        450
HDPNIFKHPE EFNPDRFLDA DGRFRKHEAF LPFSLGKRVC LGEGLAKAEL 
       460        470        480        490        500
FLFFTTILQA FSLESPCPPD TLSLKPTVSG LFNIPPASTV GMDRVNVSRV 
       510        520        530        540        550
YTAGSHIYTP AVVFRSLSHG PHAHLTHAAK MHNRTPIHNY KGHKATAGLA 
       560 
FHRHKYSPSA ITST

Note: No experimental confirmation available.

Show »

Length:564

Mass (Da):62,231

Checksum:ⁱ03B2E9376A494D12

Computationally mapped potential isoform sequencesⁱ

There are 5 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

M0R152	M0R152_HUMAN	Cytochrome P450 2S1 Cytochrome P450 2S1	CYP2S1	175	Annotation score:
M0R057	M0R057_HUMAN	Cytochrome P450 2S1 Cytochrome P450 2S1	CYP2S1	187	Annotation score:
M0R2G8	M0R2G8_HUMAN	Cytochrome P450 2S1 Cytochrome P450 2S1	CYP2S1	165	Annotation score:
M0QY51	M0QY51_HUMAN	Cytochrome P450 2S1 Cytochrome P450 2S1	CYP2S1	60	Annotation score:
M0QYI2	M0QYI2_HUMAN	Cytochrome P450 2S1 Cytochrome P450 2S1	CYP2S1	73	Annotation score:

Natural variant

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Natural variantⁱVAR_033820	466	P → L. Corresponds to variant dbSNP:rs34971233Ensembl.		1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_010531	488 – 504	FQLQV…TTQTR → STVGMDRVNVSRVYTAGSHI YTPAVVFRSLSHGPHAHLTH AAKMHNRTPIHNYKGHKATA GLAFHRHKYSPSAITST in isoform 2. 1 PublicationAdd BLAST		17

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF335278 mRNA Translation: AAK13498.1 AY358603 mRNA Translation: AAQ88966.1 AK027605 mRNA Translation: BAB55227.1 BC033691 mRNA Translation: AAH33691.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS12573.1 [Q96SQ9-1]
PIRⁱ	JC7613
NCBI Reference Sequences More...RefSeqⁱ	NP_085125.1, NM_030622.7 [Q96SQ9-1]
UniGeneⁱ	Hs.98370

Genome annotation databases

Ensemblⁱ	ENST00000310054; ENSP00000308032; ENSG00000167600 [Q96SQ9-1]
GeneIDⁱ	29785
KEGGⁱ	hsa:29785
UCSC genome browser More...UCSCⁱ	uc002opw.4 human [Q96SQ9-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing, Polymorphism

Similar proteinsⁱ

90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q96SQ9	Isoform 2 of Cytochrome P450 2S1		HUMAN		564	UniRef90_Q96SQ9
Cytochrome P450 family 2 subfamily S member 1		PONAB		563
Uncharacterized protein		CERAT		504
Uncharacterized protein		PANPA		504
Uncharacterized protein		MACNE		504
+18

Protein	Similar proteins		Species	Score	Length	Source
Q96SQ9	Isoform 2 of Cytochrome P450 2S1		HUMAN		564	UniRef50_Q96SQ9
Cytochrome P450 family 2 subfamily S member 1		PONAB		563
Uncharacterized protein		MACFA		504
CYP2S1 isoform 1		PANTR		504
Uncharacterized protein		CERAT		504
+63

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF335278 mRNA Translation: AAK13498.1 AY358603 mRNA Translation: AAQ88966.1 AK027605 mRNA Translation: BAB55227.1 BC033691 mRNA Translation: AAH33691.1
CCDSⁱ	CCDS12573.1 [Q96SQ9-1]
PIRⁱ	JC7613
RefSeqⁱ	NP_085125.1, NM_030622.7 [Q96SQ9-1]
UniGeneⁱ	Hs.98370

3D structure databases

ProteinModelPortalⁱ	Q96SQ9
SMRⁱ	Q96SQ9
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	118915, 38 interactors
IntActⁱ	Q96SQ9, 3 interactors
MINTⁱ	Q96SQ9
STRINGⁱ	9606.ENSP00000308032

Chemistry databases

SwissLipidsⁱ	SLP:000001465

SwissLipidsⁱ

SLP:000001465

PTM databases

iPTMnetⁱ	Q96SQ9
PhosphoSitePlusⁱ	Q96SQ9

Polymorphism and mutation databases

BioMutaⁱ	CYP2S1
DMDMⁱ	48428134

Proteomic databases

MaxQBⁱ	Q96SQ9
PaxDbⁱ	Q96SQ9
PeptideAtlasⁱ	Q96SQ9
PRIDEⁱ	Q96SQ9
ProteomicsDBⁱ	78138 78139 [Q96SQ9-2]

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	29785
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000310054; ENSP00000308032; ENSG00000167600 [Q96SQ9-1]
GeneIDⁱ	29785
KEGGⁱ	hsa:29785
UCSCⁱ	uc002opw.4 human [Q96SQ9-1]

Organism-specific databases

CTDⁱ	29785
DisGeNETⁱ	29785
EuPathDBⁱ	HostDB:ENSG00000167600.13
GeneCardsⁱ	CYP2S1
H-InvDBⁱ	HIX0015148
HGNCⁱ	HGNC:15654 CYP2S1
HPAⁱ	HPA049227 HPA069248
MIMⁱ	611529 gene
neXtProtⁱ	NX_Q96SQ9
OpenTargetsⁱ	ENSG00000167600
PharmGKBⁱ	PA27113
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG0156 Eukaryota COG2124 LUCA
GeneTreeⁱ	ENSGT00900000140831
HOGENOMⁱ	HOG000036992
HOVERGENⁱ	HBG015789
InParanoidⁱ	Q96SQ9
KOⁱ	K07420
OMAⁱ	KFTMLAL
OrthoDBⁱ	EOG091G0BT8
PhylomeDBⁱ	Q96SQ9
TreeFamⁱ	TF352043

Enzyme and pathway databases

Reactomeⁱ	R-HSA-211958 Miscellaneous substrates R-HSA-211981 Xenobiotics R-HSA-211999 CYP2E1 reactions

Reactomeⁱ

R-HSA-211958 Miscellaneous substrates
R-HSA-211981 Xenobiotics
R-HSA-211999 CYP2E1 reactions

Miscellaneous databases

ChiTaRSⁱ	CYP2S1 human
GeneWikiⁱ	CYP2S1
GenomeRNAiⁱ	29785
Protein Ontology More...PROⁱ	PR:Q96SQ9
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000167600 Expressed in 111 organ(s), highest expression level in jejunal mucosa
CleanExⁱ	HS_CYP2S1
ExpressionAtlasⁱ	Q96SQ9 baseline and differential
Genevisibleⁱ	Q96SQ9 HS

Family and domain databases

Gene3Dⁱ	1.10.630.10, 1 hit
InterProⁱ	View protein in InterPro IPR001128 Cyt_P450 IPR017972 Cyt_P450_CS IPR002401 Cyt_P450_E_grp-I IPR008067 Cyt_P450_E_grp-I_CYP2A-like IPR036396 Cyt_P450_sf
Pfamⁱ	View protein in Pfam PF00067 p450, 1 hit
PRINTSⁱ	PR00463 EP450I PR01684 EP450ICYP2A PR00385 P450
SUPFAMⁱ	SSF48264 SSF48264, 1 hit
PROSITEⁱ	View protein in PROSITE PS00086 CYTOCHROME_P450, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	CP2S1_HUMAN
Accessionⁱ	Q96SQ9Primary (citable) accession number: Q96SQ9 Secondary accession number(s): Q9BZ66
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	June 7, 2004
	Last sequence update:	June 7, 2004
	Last modified:	November 7, 2018
	This is version 148 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
Human chromosome 19
Human chromosome 19: entries, gene names and cross-references to MIM

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UniProtKB - Q96SQ9 (CP2S1_HUMAN)

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Cytochrome P450 2S1

CYP2S1

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Chemistry databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Endoplasmic reticulum

Endoplasmic reticulum

Other locations

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Natural variant

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Chemistry databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ