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Entry version 152 (07 Apr 2021)
Sequence version 2 (18 May 2010)
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Protein

Flt3-interacting zinc finger protein 1

Gene

FIZ1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be a transcriptional repressor of NRL function in photoreceptors. Does not repress CRX-mediated transactivation (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri23 – 45C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri51 – 73C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri79 – 101C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri107 – 130C2H2-type 4PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri200 – 222C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri228 – 250C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri331 – 352C2H2-type 7PROSITE-ProRule annotationAdd BLAST22
Zinc fingeri358 – 381C2H2-type 8PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri414 – 436C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri442 – 464C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri470 – 492C2H2-type 11PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRepressor
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q96SL8

SIGNOR Signaling Network Open Resource

More...
SIGNORi
Q96SL8

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Flt3-interacting zinc finger protein 1
Alternative name(s):
Zinc finger protein 798
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FIZ1
Synonyms:ZNF798
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:25917, FIZ1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
609133, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q96SL8

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000179943.7

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000179943

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162388597

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q96SL8, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FIZ1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
296434506

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000469371 – 496Flt3-interacting zinc finger protein 1Add BLAST496

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineCombined sources1

Keywords - PTMi

Acetylation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q96SL8

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q96SL8

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q96SL8

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q96SL8

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q96SL8

PeptideAtlas

More...
PeptideAtlasi
Q96SL8

PRoteomics IDEntifications database

More...
PRIDEi
Q96SL8

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
78127

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q96SL8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q96SL8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Widely expressed.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000179943, Expressed in cardiac muscle of right atrium and 202 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q96SL8, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q96SL8, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000179943, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with FLT3 cytoplasmic catalytic domain, following receptor stimulation, in a kinase-independent manner. Does not interact with other structurally related receptor tyrosine kinases, including KIT, CSF1R and PDGFR.

Interacts with NRL (By similarity).

By similarity

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
124357, 7 interactors

Protein interaction database and analysis system

More...
IntActi
Q96SL8, 6 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000221665

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q96SL8, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri23 – 45C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri51 – 73C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri79 – 101C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri107 – 130C2H2-type 4PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri200 – 222C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri228 – 250C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri331 – 352C2H2-type 7PROSITE-ProRule annotationAdd BLAST22
Zinc fingeri358 – 381C2H2-type 8PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri414 – 436C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri442 – 464C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri470 – 492C2H2-type 11PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153306

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_047914_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q96SL8

Identification of Orthologs from Complete Genome Data

More...
OMAi
QPAWDGG

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q96SL8

TreeFam database of animal gene trees

More...
TreeFami
TF337381

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00096, zf-C2H2, 4 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00355, ZnF_C2H2, 11 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57667, SSF57667, 6 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 10 hits
PS50157, ZINC_FINGER_C2H2_2, 11 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

Q96SL8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDDVPAPTPA PAPPAAAAPR VPFHCSECGK SFRYRSDLRR HFARHTALKP
60 70 80 90 100
HACPRCGKGF KHSFNLANHL RSHTGERPYR CSACPKGFRD STGLLHHQVV
110 120 130 140 150
HTGEKPYCCL VCELRFSSRS SLGRHLKRQH RGVLPSPLQP GPGLPALSAP
160 170 180 190 200
CSVCCNVGPC SVCGGSGAGG GEGPEGAGAG LGSWGLAEAA AAAAASLPPF
210 220 230 240 250
ACGACARRFD HGRELAAHWA AHTDVKPFKC PRCERDFNAP ALLERHKLTH
260 270 280 290 300
DLQGPGAPPA QAWAAGPGAG PETAGEGTAA EAGDAPLASD RRLLLGPAGG
310 320 330 340 350
GVPKLGGLLP EGGGEAPAPA AAAEPSEDTL YQCDCGTFFA SAAALASHLE
360 370 380 390 400
AHSGPATYGC GHCGALYAAL AALEEHRRVS HGEGGGEEAA TAAREREPAS
410 420 430 440 450
GEPPSGSGRG KKIFGCSECE KLFRSPRDLE RHVLVHTGEK PFPCLECGKF
460 470 480 490
FRHECYLKRH RLLHGTERPF PCHICGKGFI TLSNLSRHLK LHRGMD
Length:496
Mass (Da):51,996
Last modified:May 18, 2010 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD4DD7E435249B0C5
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
K7ERP0K7ERP0_HUMAN
Flt3-interacting zinc finger protei...
FIZ1
134Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7ES33K7ES33_HUMAN
Flt3-interacting zinc finger protei...
FIZ1
68Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EJE2K7EJE2_HUMAN
Flt3-interacting zinc finger protei...
FIZ1
193Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EQX6K7EQX6_HUMAN
Flt3-interacting zinc finger protei...
FIZ1
44Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAD18728 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti127K → R in BAB55286 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_060269391T → A3 PublicationsCorresponds to variant dbSNP:rs7247236Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK027674 mRNA Translation: BAB55286.1
AK160385 mRNA Translation: BAD18728.1 Different initiation.
AC008735 Genomic DNA No translation available.
CH471135 Genomic DNA Translation: EAW72392.1
BC132777 mRNA Translation: AAI32778.1
BC136512 mRNA Translation: AAI36513.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS12928.1

NCBI Reference Sequences

More...
RefSeqi
NP_116225.2, NM_032836.2
XP_005259409.1, XM_005259352.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000221665; ENSP00000221665; ENSG00000179943

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
84922

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:84922

UCSC genome browser

More...
UCSCi
uc002qli.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK027674 mRNA Translation: BAB55286.1
AK160385 mRNA Translation: BAD18728.1 Different initiation.
AC008735 Genomic DNA No translation available.
CH471135 Genomic DNA Translation: EAW72392.1
BC132777 mRNA Translation: AAI32778.1
BC136512 mRNA Translation: AAI36513.1
CCDSiCCDS12928.1
RefSeqiNP_116225.2, NM_032836.2
XP_005259409.1, XM_005259352.4

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi124357, 7 interactors
IntActiQ96SL8, 6 interactors
STRINGi9606.ENSP00000221665

PTM databases

iPTMnetiQ96SL8
PhosphoSitePlusiQ96SL8

Genetic variation databases

BioMutaiFIZ1
DMDMi296434506

Proteomic databases

EPDiQ96SL8
jPOSTiQ96SL8
MassIVEiQ96SL8
MaxQBiQ96SL8
PaxDbiQ96SL8
PeptideAtlasiQ96SL8
PRIDEiQ96SL8
ProteomicsDBi78127

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
33128, 137 antibodies

Genome annotation databases

EnsembliENST00000221665; ENSP00000221665; ENSG00000179943
GeneIDi84922
KEGGihsa:84922
UCSCiuc002qli.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
84922

GeneCards: human genes, protein and diseases

More...
GeneCardsi
FIZ1
HGNCiHGNC:25917, FIZ1
HPAiENSG00000179943, Low tissue specificity
MIMi609133, gene
neXtProtiNX_Q96SL8
OpenTargetsiENSG00000179943
PharmGKBiPA162388597
VEuPathDBiHostDB:ENSG00000179943.7

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
GeneTreeiENSGT00940000153306
HOGENOMiCLU_047914_0_0_1
InParanoidiQ96SL8
OMAiQPAWDGG
OrthoDBi1318335at2759
PhylomeDBiQ96SL8
TreeFamiTF337381

Enzyme and pathway databases

PathwayCommonsiQ96SL8
SIGNORiQ96SL8

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
84922, 7 hits in 1020 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
84922
PharosiQ96SL8, Tdark

Protein Ontology

More...
PROi
PR:Q96SL8
RNActiQ96SL8, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000179943, Expressed in cardiac muscle of right atrium and 202 other tissues
ExpressionAtlasiQ96SL8, baseline and differential
GenevisibleiQ96SL8, HS

Family and domain databases

InterProiView protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF00096, zf-C2H2, 4 hits
SMARTiView protein in SMART
SM00355, ZnF_C2H2, 11 hits
SUPFAMiSSF57667, SSF57667, 6 hits
PROSITEiView protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 10 hits
PS50157, ZINC_FINGER_C2H2_2, 11 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFIZ1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96SL8
Secondary accession number(s): A2RU72, Q6ZMJ7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: May 18, 2010
Last modified: April 7, 2021
This is version 152 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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