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Entry version 122 (17 Jun 2020)
Sequence version 2 (29 Apr 2008)
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Protein

Transmembrane protein 209

Gene

TMEM209

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transmembrane protein 209
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TMEM209
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000146842.16

Human Gene Nomenclature Database

More...
HGNCi
HGNC:21898 TMEM209

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q96SK2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei28 – 48HelicalSequence analysisAdd BLAST21
Transmembranei60 – 80HelicalSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
84928

Open Targets

More...
OpenTargetsi
ENSG00000146842

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162406425

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q96SK2 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
TMEM209

Domain mapping of disease mutations (DMDM)

More...
DMDMi
187663981

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003316321 – 561Transmembrane protein 209Add BLAST561

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei9PhosphoserineCombined sources1
Modified residuei11PhosphoserineCombined sources1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi57N-linked (GlcNAc...) asparagineSequence analysis1
Modified residuei98PhosphoserineCombined sources1
Modified residuei201PhosphoserineCombined sources1
Modified residuei222PhosphoserineCombined sources1
Modified residuei248PhosphoserineCombined sources1
Glycosylationi274N-linked (GlcNAc...) asparagineSequence analysis1
Modified residuei278PhosphoserineCombined sources1

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q96SK2

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q96SK2

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q96SK2

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q96SK2

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q96SK2

PeptideAtlas

More...
PeptideAtlasi
Q96SK2

PRoteomics IDEntifications database

More...
PRIDEi
Q96SK2

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
78118 [Q96SK2-1]
78119 [Q96SK2-2]
78120 [Q96SK2-3]
78121 [Q96SK2-4]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q96SK2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q96SK2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000146842 Expressed in metanephros and 199 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q96SK2 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q96SK2 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000146842 Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
124362, 35 interactors

Protein interaction database and analysis system

More...
IntActi
Q96SK2, 25 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000380747

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q96SK2 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q96SK2

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi131 – 222Ser-richAdd BLAST92

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4670 Eukaryota
ENOG410XQWI LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000013963

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_028470_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q96SK2

Identification of Orthologs from Complete Genome Data

More...
OMAi
NILWIFE

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q96SK2

TreeFam database of animal gene trees

More...
TreeFami
TF320043

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR019176 Cytochrome_B561-rel

The PANTHER Classification System

More...
PANTHERi
PTHR21780 PTHR21780, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF09786 CytochromB561_N, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q96SK2-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MMQGEAHPSA SLIDRTIKMR KETEARKVVL AWGLLNVSMA GMIYTEMTGK
60 70 80 90 100
LISSYYNVTY WPLWYIELAL ASLFSLNALF DFWRYFKYTV APTSLVVSPG
110 120 130 140 150
QQTLLGLKTA VVQTTPPHDL AATQIPPAPP SPSIQGQSVL SYSPSRSPST
160 170 180 190 200
SPKFTTSCMT GYSPQLQGLS SGGSGSYSPG VTYSPVSGYN KLASFSPSPP
210 220 230 240 250
SPYPTTVGPV ESSGLRSRYR SSPTVYNSPT DKEDYMTDLR TLDTFLRSEE
260 270 280 290 300
EKQHRVKLGS PDSTSPSSSP TFWNYSRSMG DYAQTLKKFQ YQLACRSQAP
310 320 330 340 350
CANKDEADLS SKQAAEEVWA RVAMNRQLLD HMDSWTAKFR NWINETILVP
360 370 380 390 400
LVQEIESVST QMRRMGCPEL QIGEASITSL KQAALVKAPL IPTLNTIVQY
410 420 430 440 450
LDLTPNQEYL FERIKELSQG GCMSSFRWNR GGDFKGRKWD TDLPTDSAII
460 470 480 490 500
MHVFCTYLDS RLPPHPKYPD GKTFTSQHFV QTPNKPDVTN ENVFCIYQSA
510 520 530 540 550
INPPHYELIY QRHVYNLPKG RNNMFHTLLM FLYIIKTKES GMLGRVNLGL
560
SGVNILWIFG E
Length:561
Mass (Da):62,922
Last modified:April 29, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0075314FEBC3DBA7
GO
Isoform 2 (identifier: Q96SK2-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: Missing.

Show »
Length:560
Mass (Da):62,790
Checksum:i15CC3FB13F7BEBA7
GO
Isoform 3 (identifier: Q96SK2-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     375-416: Missing.

Show »
Length:519
Mass (Da):58,195
Checksum:i78D7E5086190E19F
GO
Isoform 4 (identifier: Q96SK2-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     192-203: LASFSPSPPSPY → VMTLFSCLVTLF
     204-561: Missing.

Show »
Length:203
Mass (Da):22,090
Checksum:iD8622C9507C25A78
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
C9JYX1C9JYX1_HUMAN
Transmembrane protein 209
TMEM209
189Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9J5K4C9J5K4_HUMAN
Transmembrane protein 209
TMEM209
56Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti379S → G in BAC11168 (PubMed:14702039).Curated1
Sequence conflicti395N → D in BAB55314 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_042918469P → R1 PublicationCorresponds to variant dbSNP:rs17857472Ensembl.1
Natural variantiVAR_042919505H → R1 PublicationCorresponds to variant dbSNP:rs17854938Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0332801Missing in isoform 2. Curated1
Alternative sequenceiVSP_033281192 – 203LASFS…PPSPY → VMTLFSCLVTLF in isoform 4. 1 PublicationAdd BLAST12
Alternative sequenceiVSP_033282204 – 561Missing in isoform 4. 1 PublicationAdd BLAST358
Alternative sequenceiVSP_033283375 – 416Missing in isoform 3. 1 PublicationAdd BLAST42

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK027678 mRNA Translation: BAB55289.1
AK027709 mRNA Translation: BAB55314.1
AK074732 mRNA Translation: BAC11168.1
CH236950 Genomic DNA Translation: EAL24094.1
CH471070 Genomic DNA Translation: EAW83748.1
CH471070 Genomic DNA Translation: EAW83749.1
BC045618 mRNA Translation: AAH45618.1
BC057784 mRNA Translation: AAH57784.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS47712.1 [Q96SK2-1]
CCDS75661.1 [Q96SK2-3]
CCDS87547.1 [Q96SK2-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001288092.1, NM_001301163.1 [Q96SK2-3]
NP_116231.2, NM_032842.3 [Q96SK2-1]
XP_005250712.1, XM_005250655.1 [Q96SK2-2]
XP_011514948.1, XM_011516646.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000397622; ENSP00000380747; ENSG00000146842 [Q96SK2-1]
ENST00000462753; ENSP00000419697; ENSG00000146842 [Q96SK2-2]
ENST00000473456; ENSP00000417258; ENSG00000146842 [Q96SK2-3]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
84928

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:84928

UCSC genome browser

More...
UCSCi
uc003vpn.2 human [Q96SK2-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK027678 mRNA Translation: BAB55289.1
AK027709 mRNA Translation: BAB55314.1
AK074732 mRNA Translation: BAC11168.1
CH236950 Genomic DNA Translation: EAL24094.1
CH471070 Genomic DNA Translation: EAW83748.1
CH471070 Genomic DNA Translation: EAW83749.1
BC045618 mRNA Translation: AAH45618.1
BC057784 mRNA Translation: AAH57784.1
CCDSiCCDS47712.1 [Q96SK2-1]
CCDS75661.1 [Q96SK2-3]
CCDS87547.1 [Q96SK2-2]
RefSeqiNP_001288092.1, NM_001301163.1 [Q96SK2-3]
NP_116231.2, NM_032842.3 [Q96SK2-1]
XP_005250712.1, XM_005250655.1 [Q96SK2-2]
XP_011514948.1, XM_011516646.2

3D structure databases

SMRiQ96SK2
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi124362, 35 interactors
IntActiQ96SK2, 25 interactors
STRINGi9606.ENSP00000380747

PTM databases

iPTMnetiQ96SK2
PhosphoSitePlusiQ96SK2

Polymorphism and mutation databases

BioMutaiTMEM209
DMDMi187663981

Proteomic databases

EPDiQ96SK2
jPOSTiQ96SK2
MassIVEiQ96SK2
MaxQBiQ96SK2
PaxDbiQ96SK2
PeptideAtlasiQ96SK2
PRIDEiQ96SK2
ProteomicsDBi78118 [Q96SK2-1]
78119 [Q96SK2-2]
78120 [Q96SK2-3]
78121 [Q96SK2-4]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
32026 54 antibodies

The DNASU plasmid repository

More...
DNASUi
84928

Genome annotation databases

EnsembliENST00000397622; ENSP00000380747; ENSG00000146842 [Q96SK2-1]
ENST00000462753; ENSP00000419697; ENSG00000146842 [Q96SK2-2]
ENST00000473456; ENSP00000417258; ENSG00000146842 [Q96SK2-3]
GeneIDi84928
KEGGihsa:84928
UCSCiuc003vpn.2 human [Q96SK2-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
84928
DisGeNETi84928
EuPathDBiHostDB:ENSG00000146842.16

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TMEM209
HGNCiHGNC:21898 TMEM209
HPAiENSG00000146842 Low tissue specificity
neXtProtiNX_Q96SK2
OpenTargetsiENSG00000146842
PharmGKBiPA162406425

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG4670 Eukaryota
ENOG410XQWI LUCA
GeneTreeiENSGT00390000013963
HOGENOMiCLU_028470_0_0_1
InParanoidiQ96SK2
OMAiNILWIFE
PhylomeDBiQ96SK2
TreeFamiTF320043

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
84928 16 hits in 792 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
TMEM209 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
84928
PharosiQ96SK2 Tdark

Protein Ontology

More...
PROi
PR:Q96SK2
RNActiQ96SK2 protein

Gene expression databases

BgeeiENSG00000146842 Expressed in metanephros and 199 other tissues
ExpressionAtlasiQ96SK2 baseline and differential
GenevisibleiQ96SK2 HS

Family and domain databases

InterProiView protein in InterPro
IPR019176 Cytochrome_B561-rel
PANTHERiPTHR21780 PTHR21780, 1 hit
PfamiView protein in Pfam
PF09786 CytochromB561_N, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTM209_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96SK2
Secondary accession number(s): A4D1L1
, Q49A50, Q6PF00, Q8NCH3, Q96SL6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: April 29, 2008
Last modified: June 17, 2020
This is version 122 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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