UniProtKB - Q96S90 (LYSM1_HUMAN)
Protein
LysM and putative peptidoglycan-binding domain-containing protein 1
Gene
LYSMD1
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Recommended name: LysM and putative peptidoglycan-binding domain-containing protein 1 |
Gene namesi | Name:LYSMD1 ORF Names:SB145 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000163155.11 |
HGNCi | HGNC:32070, LYSMD1 |
neXtProti | NX_Q96S90 |
Subcellular locationi
Nucleus
- nucleoplasm Source: HPA
Pathology & Biotechi
Organism-specific databases
OpenTargetsi | ENSG00000163155 |
PharmGKBi | PA142671493 |
Miscellaneous databases
Pharosi | Q96S90, Tdark |
Polymorphism and mutation databases
BioMutai | LYSMD1 |
DMDMi | 74752122 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000247996 | 1 – 227 | LysM and putative peptidoglycan-binding domain-containing protein 1Add BLAST | 227 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 23 | PhosphoserineCombined sources | 1 | |
Modified residuei | 33 | PhosphoserineCombined sources | 1 | |
Modified residuei | 99 | PhosphoserineCombined sources | 1 | |
Modified residuei | 166 | PhosphoserineCombined sources | 1 | |
Modified residuei | 194 | PhosphoserineBy similarity | 1 | |
Modified residuei | 212 | PhosphoserineCombined sources | 1 |
Keywords - PTMi
PhosphoproteinProteomic databases
EPDi | Q96S90 |
jPOSTi | Q96S90 |
MassIVEi | Q96S90 |
MaxQBi | Q96S90 |
PaxDbi | Q96S90 |
PeptideAtlasi | Q96S90 |
PRIDEi | Q96S90 |
ProteomicsDBi | 78085 [Q96S90-1] 78086 [Q96S90-2] |
PTM databases
iPTMneti | Q96S90 |
PhosphoSitePlusi | Q96S90 |
Expressioni
Gene expression databases
Bgeei | ENSG00000163155, Expressed in amniotic fluid and 164 other tissues |
Genevisiblei | Q96S90, HS |
Organism-specific databases
HPAi | ENSG00000163155, Low tissue specificity |
Interactioni
Binary interactionsi
Hide detailsQ96S90
Protein-protein interaction databases
BioGRIDi | 132813, 12 interactors |
IntActi | Q96S90, 14 interactors |
STRINGi | 9606.ENSP00000357904 |
Miscellaneous databases
RNActi | Q96S90, protein |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | Q96S90 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q96S90 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 40 – 84 | LysMPROSITE-ProRule annotationAdd BLAST | 45 |
Phylogenomic databases
eggNOGi | ENOG502RZER, Eukaryota |
GeneTreei | ENSGT00940000160002 |
HOGENOMi | CLU_079453_0_0_1 |
InParanoidi | Q96S90 |
OMAi | KGCQEAE |
OrthoDBi | 1553362at2759 |
PhylomeDBi | Q96S90 |
TreeFami | TF318444 |
Family and domain databases
CDDi | cd00118, LysM, 1 hit |
Gene3Di | 3.10.350.10, 1 hit |
InterProi | View protein in InterPro IPR018392, LysM_dom IPR036779, LysM_dom_sf |
Pfami | View protein in Pfam PF01476, LysM, 1 hit |
SMARTi | View protein in SMART SM00257, LysM, 1 hit |
PROSITEi | View protein in PROSITE PS51782, LYSM, 1 hit |
s (2)i Sequence
Sequence statusi: Complete.
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketIsoform 1 (identifier: Q96S90-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MASPSRQPPP GGSGLLQGSR ARSYGSLVQS ACSPVRERRL EHQLEPGDTL
60 70 80 90 100
AGLALKYGVT MEQIKRANRL YTNDSIFLKK TLYIPILTEP RDLFNGLDSE
110 120 130 140 150
EEKDGEEKVH PSNSEVWPHS TERKKQETGA GRANGEVLPT PGQETPTPIH
160 170 180 190 200
DLSASDFLKK LDSQISLSKK AAAQKLKKGE NGVPGEDAGL HLSSPWMQQR
210 220
AVLGPVPLTR TSRTRTLRDQ EDEIFKL
Sequence cautioni
The sequence CAH10716 differs from that shown. Reason: Erroneous initiation.Curated
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 128 | T → G in CAH10716 (PubMed:17974005).Curated | 1 | |
Sequence conflicti | 164 | Q → R in BAG60863 (PubMed:14702039).Curated | 1 | |
Sequence conflicti | 198 | Q → R in CAH10716 (PubMed:17974005).Curated | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_041083 | 1 – 60 | MASPS…KYGVT → MRSGPLRISEWK in isoform 2. 1 PublicationAdd BLAST | 60 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY037156 mRNA Translation: AAK67635.1 AK298706 mRNA Translation: BAG60863.1 AL122088 mRNA Translation: CAH10716.1 Different initiation. BX647911 mRNA Translation: CAH10574.1 AL592424 Genomic DNA No translation available. BC031649 mRNA Translation: AAH31649.1 |
CCDSi | CCDS44218.1 [Q96S90-2] CCDS986.1 [Q96S90-1] |
RefSeqi | NP_001130015.1, NM_001136543.1 [Q96S90-2] NP_997716.1, NM_212551.4 [Q96S90-1] |
Genome annotation databases
Ensembli | ENST00000368908; ENSP00000357904; ENSG00000163155 [Q96S90-1] ENST00000440902; ENSP00000404059; ENSG00000163155 [Q96S90-2] |
GeneIDi | 388695 |
KEGGi | hsa:388695 |
UCSCi | uc001ewy.4, human [Q96S90-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY037156 mRNA Translation: AAK67635.1 AK298706 mRNA Translation: BAG60863.1 AL122088 mRNA Translation: CAH10716.1 Different initiation. BX647911 mRNA Translation: CAH10574.1 AL592424 Genomic DNA No translation available. BC031649 mRNA Translation: AAH31649.1 |
CCDSi | CCDS44218.1 [Q96S90-2] CCDS986.1 [Q96S90-1] |
RefSeqi | NP_001130015.1, NM_001136543.1 [Q96S90-2] NP_997716.1, NM_212551.4 [Q96S90-1] |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
2DJP | NMR | - | A | 32-95 | [»] | |
SMRi | Q96S90 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 132813, 12 interactors |
IntActi | Q96S90, 14 interactors |
STRINGi | 9606.ENSP00000357904 |
PTM databases
iPTMneti | Q96S90 |
PhosphoSitePlusi | Q96S90 |
Polymorphism and mutation databases
BioMutai | LYSMD1 |
DMDMi | 74752122 |
Proteomic databases
EPDi | Q96S90 |
jPOSTi | Q96S90 |
MassIVEi | Q96S90 |
MaxQBi | Q96S90 |
PaxDbi | Q96S90 |
PeptideAtlasi | Q96S90 |
PRIDEi | Q96S90 |
ProteomicsDBi | 78085 [Q96S90-1] 78086 [Q96S90-2] |
Protocols and materials databases
Antibodypediai | 34054, 113 antibodies |
DNASUi | 388695 |
Genome annotation databases
Ensembli | ENST00000368908; ENSP00000357904; ENSG00000163155 [Q96S90-1] ENST00000440902; ENSP00000404059; ENSG00000163155 [Q96S90-2] |
GeneIDi | 388695 |
KEGGi | hsa:388695 |
UCSCi | uc001ewy.4, human [Q96S90-1] |
Organism-specific databases
CTDi | 388695 |
EuPathDBi | HostDB:ENSG00000163155.11 |
GeneCardsi | LYSMD1 |
HGNCi | HGNC:32070, LYSMD1 |
HPAi | ENSG00000163155, Low tissue specificity |
neXtProti | NX_Q96S90 |
OpenTargetsi | ENSG00000163155 |
PharmGKBi | PA142671493 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG502RZER, Eukaryota |
GeneTreei | ENSGT00940000160002 |
HOGENOMi | CLU_079453_0_0_1 |
InParanoidi | Q96S90 |
OMAi | KGCQEAE |
OrthoDBi | 1553362at2759 |
PhylomeDBi | Q96S90 |
TreeFami | TF318444 |
Enzyme and pathway databases
PathwayCommonsi | Q96S90 |
Miscellaneous databases
BioGRID-ORCSi | 388695, 11 hits in 842 CRISPR screens |
ChiTaRSi | LYSMD1, human |
EvolutionaryTracei | Q96S90 |
GenomeRNAii | 388695 |
Pharosi | Q96S90, Tdark |
PROi | PR:Q96S90 |
RNActi | Q96S90, protein |
Gene expression databases
Bgeei | ENSG00000163155, Expressed in amniotic fluid and 164 other tissues |
Genevisiblei | Q96S90, HS |
Family and domain databases
CDDi | cd00118, LysM, 1 hit |
Gene3Di | 3.10.350.10, 1 hit |
InterProi | View protein in InterPro IPR018392, LysM_dom IPR036779, LysM_dom_sf |
Pfami | View protein in Pfam PF01476, LysM, 1 hit |
SMARTi | View protein in SMART SM00257, LysM, 1 hit |
PROSITEi | View protein in PROSITE PS51782, LYSM, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | LYSM1_HUMAN | |
Accessioni | Q96S90Primary (citable) accession number: Q96S90 Secondary accession number(s): B4DQA1, Q69YX9 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | September 5, 2006 |
Last sequence update: | December 1, 2001 | |
Last modified: | December 2, 2020 | |
This is version 145 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - Human chromosome 1
Human chromosome 1: entries, gene names and cross-references to MIM