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Entry version 113 (02 Jun 2021)
Sequence version 2 (20 May 2008)
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Protein

Methyltransferase-like 26

Gene

METTL26

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q96S19

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Methyltransferase-like 26Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:METTL26Imported
Synonyms:JFP2
ORF Names:C16orf13
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 16

Organism-specific databases

Human Gene Nomenclature Database

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HGNCi
HGNC:14141, METTL26

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q96S19

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000130731.15

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000130731

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA25526

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q96S19, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
METTL26

Domain mapping of disease mutations (DMDM)

More...
DMDMi
189082900

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003371141 – 204Methyltransferase-like 26Add BLAST204

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineCombined sources1 Publication1
Modified residuei149PhosphoserineBy similarity1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
Q96S19

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
Q96S19

MassIVE - Mass Spectrometry Interactive Virtual Environment

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MassIVEi
Q96S19

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q96S19

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
Q96S19

PeptideAtlas

More...
PeptideAtlasi
Q96S19

PRoteomics IDEntifications database

More...
PRIDEi
Q96S19

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
14271
27969
28082
78056 [Q96S19-1]
78057 [Q96S19-2]
78058 [Q96S19-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q96S19

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q96S19

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSG00000130731, Expressed in quadriceps femoris and 210 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q96S19, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q96S19, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000130731, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

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BioGRIDi
124050, 3 interactors

Protein interaction database and analysis system

More...
IntActi
Q96S19, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000440765

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q96S19, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the UPF0585 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502SNXQ, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000010750

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_067698_2_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q96S19

Identification of Orthologs from Complete Genome Data

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OMAi
NPEWGVR

Database of Orthologous Groups

More...
OrthoDBi
1359763at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q96S19

TreeFam database of animal gene trees

More...
TreeFami
TF315025

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR010342, DUF938
IPR029063, SAM-dependent_MTases

The PANTHER Classification System

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PANTHERi
PTHR20974, PTHR20974, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF06080, DUF938, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53335, SSF53335, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (6+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 6 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 6 described isoforms and 7 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q96S19-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MLVAAAAERN KDPILHVLRQ YLDPAQRGVR VLEVASGSGQ HAAHFARAFP
60 70 80 90 100
LAEWQPSDVD QRCLDSIAAT TQAQGLTNVK APLHLDVTWG WEHWGGILPQ
110 120 130 140 150
SLDLLLCINM AHVSPLRCTE GLFRAAGHLL KPRALLITYG PYAINGKISP
160 170 180 190 200
QSNVDFDLML RCRNPEWGLR DTALLEDLGK ASGLLLERMV DMPANNKCLI

FRKN
Length:204
Mass (Da):22,578
Last modified:May 20, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD927CBB1151FC753
GO
Isoform 2 (identifier: Q96S19-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     66-204: SIAATTQAQG...NNKCLIFRKN → RCGPRGGHFY...PLLNVPPSLP

Show »
Length:147
Mass (Da):15,015
Checksum:iD8E32F57B9CC396F
GO
Isoform 3 (identifier: Q96S19-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     66-162: Missing.

Show »
Length:107
Mass (Da):11,975
Checksum:i03AC55C1AAC3853B
GO
Isoform 4 (identifier: Q96S19-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     141-204: PYAINGKISP...NNKCLIFRKN → EPRMGASGHS...RLCEARTLPP

Show »
Length:205
Mass (Da):22,158
Checksum:iD4E8BCCA2C040CFE
GO
Isoform 5 (identifier: Q96S19-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     66-163: SIAATTQAQG...VDFDLMLRCR → RGSSEQQDTCSNPGPCSSPTG

Show »
Length:127
Mass (Da):13,896
Checksum:iDEDCC69D97E26C41
GO
Isoform 6 (identifier: Q96S19-6) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     121-204: GLFRAAGHLL...NNKCLIFRKN → EPRMGASGHS...RLCEARTLPP

Show »
Length:185
Mass (Da):20,009
Checksum:iFB66FF846FBB73A6
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H3BRT2H3BRT2_HUMAN
Methyltransferase-like 26
METTL26
133Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BNB2H3BNB2_HUMAN
Methyltransferase-like 26
METTL26
174Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BNT3H3BNT3_HUMAN
Methyltransferase-like 26
METTL26
162Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BS73H3BS73_HUMAN
Methyltransferase-like 26
METTL26
103Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WYU2A0A087WYU2_HUMAN
Methyltransferase-like 26
METTL26
184Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BMF3H3BMF3_HUMAN
Methyltransferase-like 26
METTL26
176Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H3BQ55H3BQ55_HUMAN
Methyltransferase-like 26
METTL26
161Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAK61238 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence EAW85785 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Isoform 4 (identifier: Q96S19-4)
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti196R → G in BAG58505 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_064368136L → P1 PublicationCorresponds to variant dbSNP:rs865791888Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_03391866 – 204SIAAT…IFRKN → RCGPRGGHFYRCGGPGPQEP TARSPGGKGCGSGSEGAGWE PGGAPGAGPSCAAPAAAEVG GPRGPPSQPLWSPLLNVPPS LP in isoform 2. 2 PublicationsAdd BLAST139
Alternative sequenceiVSP_04683866 – 163SIAAT…MLRCR → RGSSEQQDTCSNPGPCSSPT G in isoform 5. CuratedAdd BLAST98
Alternative sequenceiVSP_03391966 – 162Missing in isoform 3. 1 PublicationAdd BLAST97
Alternative sequenceiVSP_046839121 – 204GLFRA…IFRKN → EPRMGASGHSPPGGPGKGQW PAPGEDGGHASQQQMPDLPE KLSPSFTPAHLHPCRRLCEA RTLPP in isoform 6. CuratedAdd BLAST84
Alternative sequenceiVSP_045804141 – 204PYAIN…IFRKN → EPRMGASGHSPPGGPGKGQW PAPGEDGGHASQQQMPDLPE KLSPSFTPAHLHPCRRLCEA RTLPP in isoform 4. 1 PublicationAdd BLAST64

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK057077 mRNA Translation: BAB71362.1
AK293046 mRNA Translation: BAF85735.1
AK294482 mRNA Translation: BAG57706.1
AK295628 mRNA Translation: BAG58505.1
AE006464 Genomic DNA Translation: AAK61238.1 Sequence problems.
Z84479 Genomic DNA No translation available.
CH471112 Genomic DNA Translation: EAW85787.1
CH471112 Genomic DNA Translation: EAW85785.1 Sequence problems.
CH471112 Genomic DNA Translation: EAW85786.1
CH471112 Genomic DNA Translation: EAW85788.1
BC007207 mRNA Translation: AAH07207.1
BC047118 mRNA Translation: AAH47118.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS32352.1 [Q96S19-3]
CCDS42090.1 [Q96S19-6]
CCDS42091.1 [Q96S19-4]
CCDS45367.1 [Q96S19-5]
CCDS45368.1 [Q96S19-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001035250.1, NM_001040160.2 [Q96S19-4]
NP_001035251.1, NM_001040161.2 [Q96S19-3]
NP_001035252.1, NM_001040162.2 [Q96S19-5]
NP_001035255.1, NM_001040165.2 [Q96S19-6]
NP_115742.3, NM_032366.4 [Q96S19-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000301686; ENSP00000445926; ENSG00000130731 [Q96S19-1]
ENST00000338401; ENSP00000444140; ENSG00000130731 [Q96S19-3]
ENST00000397664; ENSP00000440475; ENSG00000130731 [Q96S19-5]
ENST00000397665; ENSP00000444460; ENSG00000130731 [Q96S19-6]
ENST00000397666; ENSP00000440765; ENSG00000130731 [Q96S19-4]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
84326

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:84326

UCSC genome browser

More...
UCSCi
uc002chv.3, human [Q96S19-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK057077 mRNA Translation: BAB71362.1
AK293046 mRNA Translation: BAF85735.1
AK294482 mRNA Translation: BAG57706.1
AK295628 mRNA Translation: BAG58505.1
AE006464 Genomic DNA Translation: AAK61238.1 Sequence problems.
Z84479 Genomic DNA No translation available.
CH471112 Genomic DNA Translation: EAW85787.1
CH471112 Genomic DNA Translation: EAW85785.1 Sequence problems.
CH471112 Genomic DNA Translation: EAW85786.1
CH471112 Genomic DNA Translation: EAW85788.1
BC007207 mRNA Translation: AAH07207.1
BC047118 mRNA Translation: AAH47118.1
CCDSiCCDS32352.1 [Q96S19-3]
CCDS42090.1 [Q96S19-6]
CCDS42091.1 [Q96S19-4]
CCDS45367.1 [Q96S19-5]
CCDS45368.1 [Q96S19-1]
RefSeqiNP_001035250.1, NM_001040160.2 [Q96S19-4]
NP_001035251.1, NM_001040161.2 [Q96S19-3]
NP_001035252.1, NM_001040162.2 [Q96S19-5]
NP_001035255.1, NM_001040165.2 [Q96S19-6]
NP_115742.3, NM_032366.4 [Q96S19-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi124050, 3 interactors
IntActiQ96S19, 1 interactor
STRINGi9606.ENSP00000440765

PTM databases

iPTMnetiQ96S19
PhosphoSitePlusiQ96S19

Genetic variation databases

BioMutaiMETTL26
DMDMi189082900

Proteomic databases

EPDiQ96S19
jPOSTiQ96S19
MassIVEiQ96S19
MaxQBiQ96S19
PaxDbiQ96S19
PeptideAtlasiQ96S19
PRIDEiQ96S19
ProteomicsDBi14271
27969
28082
78056 [Q96S19-1]
78057 [Q96S19-2]
78058 [Q96S19-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

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Antibodypediai
51680, 70 antibodies

The DNASU plasmid repository

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DNASUi
84326

Genome annotation databases

EnsembliENST00000301686; ENSP00000445926; ENSG00000130731 [Q96S19-1]
ENST00000338401; ENSP00000444140; ENSG00000130731 [Q96S19-3]
ENST00000397664; ENSP00000440475; ENSG00000130731 [Q96S19-5]
ENST00000397665; ENSP00000444460; ENSG00000130731 [Q96S19-6]
ENST00000397666; ENSP00000440765; ENSG00000130731 [Q96S19-4]
GeneIDi84326
KEGGihsa:84326
UCSCiuc002chv.3, human [Q96S19-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
84326

GeneCards: human genes, protein and diseases

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GeneCardsi
METTL26
HGNCiHGNC:14141, METTL26
HPAiENSG00000130731, Low tissue specificity
neXtProtiNX_Q96S19
OpenTargetsiENSG00000130731
PharmGKBiPA25526
VEuPathDBiHostDB:ENSG00000130731.15

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiENOG502SNXQ, Eukaryota
GeneTreeiENSGT00390000010750
HOGENOMiCLU_067698_2_0_1
InParanoidiQ96S19
OMAiNPEWGVR
OrthoDBi1359763at2759
PhylomeDBiQ96S19
TreeFamiTF315025

Enzyme and pathway databases

PathwayCommonsiQ96S19

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
84326, 5 hits in 974 CRISPR screens

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
Chromosome_16_open_reading_frame_13

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
84326
PharosiQ96S19, Tdark

Protein Ontology

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PROi
PR:Q96S19
RNActiQ96S19, protein

Gene expression databases

BgeeiENSG00000130731, Expressed in quadriceps femoris and 210 other tissues
ExpressionAtlasiQ96S19, baseline and differential
GenevisibleiQ96S19, HS

Family and domain databases

InterProiView protein in InterPro
IPR010342, DUF938
IPR029063, SAM-dependent_MTases
PANTHERiPTHR20974, PTHR20974, 1 hit
PfamiView protein in Pfam
PF06080, DUF938, 1 hit
SUPFAMiSSF53335, SSF53335, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMTL26_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96S19
Secondary accession number(s): A8MTR1
, A8MWJ8, A8MZA1, B4DG95, B4DIJ3, D6REA6, F6TF62, F6VM53, Q96IW1, Q96MD6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 20, 2008
Last modified: June 2, 2021
This is version 113 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing, Reference proteome

Documents

  1. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries
  2. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM
  3. Human entries with genetic variants
    List of human entries with genetic variants
  4. Human variants curated from literature reports
    Index of human variants curated from literature reports
  5. SIMILARITY comments
    Index of protein domains and families
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