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UniProtKB - Q96RT6 (CTGE2_HUMAN)

Entry version 117 (16 Oct 2019)
Sequence version 2 (14 Oct 2008)
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Protein

cTAGE family member 2

Gene

CTAGE1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
cTAGE family member 2
Short name:
Protein cTAGE-2
Alternative name(s):
Cancer/testis antigen 21.2
Short name:
CT21.2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CTAGE1
Synonyms:CTAGE2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 18

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:24346 CTAGE1

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		608856 gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q96RT6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei13 – 30HelicalSequence analysisAdd BLAST18

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		64693

Open Targets

More...OpenTargetsi		ENSG00000212710

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134933936

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q96RT6

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		CTAGE1

Domain mapping of disease mutations (DMDM)

More...DMDMi		209572622

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001895381 – 745cTAGE family member 2Add BLAST745

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei267PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q96RT6

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q96RT6

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q96RT6

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q96RT6

PeptideAtlas

More...PeptideAtlasi		Q96RT6

PRoteomics IDEntifications database

More...PRIDEi		Q96RT6

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		78028 [Q96RT6-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q96RT6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q96RT6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Testis. Not found in tumor.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000212710 Expressed in 20 organ(s), highest expression level in sperm

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q96RT6 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q96RT6 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		CAB016204
HPA000387
HPA000922

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		122233, 1 interactor

Protein interaction database and analysis system

More...IntActi		Q96RT6, 6 interactors

Molecular INTeraction database

More...MINTi		Q96RT6

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000375220

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q96RT6

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili84 – 254Sequence analysisAdd BLAST171
Coiled coili290 – 411Sequence analysisAdd BLAST122

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi658 – 743Pro-richAdd BLAST86

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the cTAGE family.Curated

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

Ensembl GeneTree

More...GeneTreei		ENSGT00950000182767

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q96RT6

Identification of Orthologs from Complete Genome Data

More...OMAi		EXLLQEA

Database of Orthologous Groups

More...OrthoDBi		135910at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q96RT6

TreeFam database of animal gene trees

More...TreeFami		TF333137

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Note: Additional isoforms (cTAGE-1B, cTAGE-1C and cTAGE-2s) exist.
Isoform 2 (identifier: Q96RT6-1) [UniParc]FASTAAdd to basket
Also known as: cTAGE-2

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MRPDSHPYGF PWELVIRAAV AGFFAVLFLW RSFRSVTSRL YVRREKKFAV 
        60         70         80         90        100
ALSGLIEEKC KLLEKFSLVQ KEYEGYEVES SLKNASFEKE ATEAQSLEAT 
       110        120        130        140        150
CEKLNRFNSE LVHEILCLEK ELKEEKSKHS EQNELMADIS KRIQSLEDES 
       160        170        180        190        200
KSLKSQVAEA KMTFKRFQAN EERLEIEIQD AWKENSELQE SQKQLLQEAE 
       210        220        230        240        250
VWKEQVSELI KQKRTFEDSK VHAEQVLNDK ENHIKTLTER LLKMKDGVAM 
       260        270        280        290        300
LEEDVTDDDN LELEMNSESE DGAYLDNPPK GALKKLIHAA KLNASLKTLE 
       310        320        330        340        350
GERNQIYIQL SEVDKTKEEL TEHIKNLQTE QASLQSENTH FESENQKLQQ 
       360        370        380        390        400
KLKVMTELYQ ENEMKLYRKL IVEEKCRLEK EEKLSKVDEM ISHATEELET 
       410        420        430        440        450
YRKRAKDLKE FEKTIHFYQK KIILHEKKAH DNWSAAWTAE RNLNDLRKEN 
       460        470        480        490        500
AHNRQKLTEI EFKIKLLEKD PYGLDVPNTA FGRQHSPYGP SPLGWPSSET 
       510        520        530        540        550
RASLYPPTLL EGPLRLSPLL PRGGGRGSRG PGNPPDHQIT KERGESSCDR 
       560        570        580        590        600
LTDPHRAPSD AGPLAPPWEQ DYRMMFPPPG QSYPDSALPP QRQDRFYSNC 
       610        620        630        640        650
ARLSGPAELR SFNMPSLDKM DGSMPSEMES SRNDTKDNLG NLKVPDSSLP 
       660        670        680        690        700
AENEATGPGF VPPPLAPIRG LLFPVDTRGP FIRRGPPFPP PPPGTVFGAS 
       710        720        730        740 
PDYFSPRDVP GPPRAPFAMR NVYLPRGFLP YRPPRPAFFP PAPTF
Length:745
Mass (Da):85,282
Last modified:October 14, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE3E6B1219651CA61
GO
Isoform 1 (identifier: Q9HC47-1) [UniParc]FASTAAdd to basket
Also known as: cTAGE-1
The sequence of this isoform can be found in the external entry Q9HC47.
Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.
Length:74
Mass (Da):8,406
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAK63198 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti179Q → R in AAK63198 (PubMed:12839582).Curated1
Sequence conflicti312E → G in AAK63198 (PubMed:12839582).Curated1
Sequence conflicti430H → R in AAK63198 (PubMed:12839582).Curated1
Sequence conflicti635T → A in AAK63198 (PubMed:12839582).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_046956682I → V. Corresponds to variant dbSNP:rs9946136Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF273058 mRNA Translation: AAK63198.1 Frameshift.
AC099849 Genomic DNA No translation available.
BC132871 mRNA Translation: AAI32872.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS45837.1 [Q96RT6-1]

NCBI Reference Sequences

More...RefSeqi		NP_758441.2, NM_172241.2 [Q96RT6-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000391403; ENSP00000375220; ENSG00000212710 [Q96RT6-1]
ENST00000634260; ENSP00000489019; ENSG00000282841 [Q96RT6-1]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		64693

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:64693

UCSC genome browser

More...UCSCi		uc002ktv.2 human [Q96RT6-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF273058 mRNA Translation: AAK63198.1 Frameshift.
AC099849 Genomic DNA No translation available.
BC132871 mRNA Translation: AAI32872.1
CCDSiCCDS45837.1 [Q96RT6-1]
RefSeqiNP_758441.2, NM_172241.2 [Q96RT6-1]

3D structure databases

SMRiQ96RT6
ModBaseiSearch...

Protein-protein interaction databases

BioGridi122233, 1 interactor
IntActiQ96RT6, 6 interactors
MINTiQ96RT6
STRINGi9606.ENSP00000375220

PTM databases

iPTMnetiQ96RT6
PhosphoSitePlusiQ96RT6

Polymorphism and mutation databases

BioMutaiCTAGE1
DMDMi209572622

Proteomic databases

EPDiQ96RT6
jPOSTiQ96RT6
MassIVEiQ96RT6
PaxDbiQ96RT6
PeptideAtlasiQ96RT6
PRIDEiQ96RT6
ProteomicsDBi78028 [Q96RT6-1]

Protocols and materials databases

The DNASU plasmid repository

More...DNASUi		64693

Genome annotation databases

EnsembliENST00000391403; ENSP00000375220; ENSG00000212710 [Q96RT6-1]
ENST00000634260; ENSP00000489019; ENSG00000282841 [Q96RT6-1]
GeneIDi64693
KEGGihsa:64693
UCSCiuc002ktv.2 human [Q96RT6-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		64693
DisGeNETi64693

GeneCards: human genes, protein and diseases

More...GeneCardsi		CTAGE1
HGNCiHGNC:24346 CTAGE1
HPAiCAB016204
HPA000387
HPA000922
MIMi608856 gene
neXtProtiNX_Q96RT6
OpenTargetsiENSG00000212710
PharmGKBiPA134933936

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

GeneTreeiENSGT00950000182767
InParanoidiQ96RT6
OMAiEXLLQEA
OrthoDBi135910at2759
PhylomeDBiQ96RT6
TreeFamiTF333137

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		64693
PharosiQ96RT6

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000212710 Expressed in 20 organ(s), highest expression level in sperm
ExpressionAtlasiQ96RT6 baseline and differential
GenevisibleiQ96RT6 HS

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCTGE2_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96RT6
Secondary accession number(s): A2RUF2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 4, 2005
Last sequence update: October 14, 2008
Last modified: October 16, 2019
This is version 117 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. Human chromosome 18
    Human chromosome 18: entries, gene names and cross-references to MIM
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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