FYTTD1

Functionⁱ

Required for mRNA export from the nucleus to the cytoplasm. Acts as an adapter that uses the DDX39B/UAP56-NFX1 pathway to ensure efficient mRNA export and delivering to the nuclear pore. Associates with spliced and unspliced mRNAs simultaneously with ALYREF/THOC4.1 Publication

GO - Molecular functionⁱ

mRNA binding
Source: UniProtKB
Inferred from direct assayⁱ
- 19836239
RNA binding
Source: UniProtKB
Inferred from high throughput direct assayⁱ
- 22681889

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

mRNA export from nucleus
Source: UniProtKB
Inferred from mutant phenotypeⁱ
- 19836239

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	RNA-binding
Biological process	mRNA transport, Transport

Enzyme and pathway databases

Reactomeⁱ	R-HSA-109688 Cleavage of Growing Transcript in the Termination Region R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-72187 mRNA 3'-end processing

Reactomeⁱ

R-HSA-109688 Cleavage of Growing Transcript in the Termination Region
R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript
R-HSA-72187 mRNA 3'-end processing

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: UAP56-interacting factor Alternative name(s): Forty-two-three domain-containing protein 1 Short name: Protein 40-2-3
Gene namesⁱ	Name:FYTTD1 Synonyms:UIF
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 3

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000122068.12
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:25407 FYTTD1
MIMⁱ	616933 gene
neXtProtⁱ	NX_Q96QD9

Keywords - Cellular componentⁱ

Nucleus

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000122068
PharmGKBⁱ	PA134946373

Polymorphism and mutation databases

BioMutaⁱ	FYTTD1
DMDMⁱ	284018159

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000287441	1 – 318	UAP56-interacting factorAdd BLAST		318

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Modified residueⁱ	1	N-acetylmethionineCombined sources	1
Modified residueⁱ	14	PhosphothreonineBy similarity	1
Modified residueⁱ	16	PhosphoserineCombined sources	1
Modified residueⁱ	23	PhosphoserineCombined sources	1
Modified residueⁱ	61	PhosphoserineCombined sources	1
Modified residueⁱ	118	PhosphoserineCombined sources	1
Cross-linkⁱ	140	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)
Cross-linkⁱ	261	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources

Keywords - PTMⁱ

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDⁱ	Q96QD9
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q96QD9
PaxDbⁱ	Q96QD9
PeptideAtlas More...PeptideAtlasⁱ	Q96QD9
PRIDEⁱ	Q96QD9
ProteomicsDBⁱ	77857 77858 [Q96QD9-2] 77859 [Q96QD9-3] 77860 [Q96QD9-4]
TopDownProteomicsⁱ	Q96QD9-1 [Q96QD9-1]

PTM databases

iPTMnetⁱ	Q96QD9
PhosphoSitePlusⁱ	Q96QD9

Expressionⁱ

Tissue specificityⁱ

Expressed in a wide variety of cancer types.1 Publication

Gene expression databases

Bgeeⁱ	ENSG00000122068 Expressed in 205 organ(s), highest expression level in quadriceps femoris
CleanExⁱ	HS_FYTTD1
ExpressionAtlasⁱ	Q96QD9 baseline and differential
Genevisibleⁱ	Q96QD9 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA054474

HPAⁱ

HPA054474

Interactionⁱ

Subunit structureⁱ

Interacts with CHTOP (By similarity). Interacts with DDX39B/UAP56 and NXF1; interaction with DDX39B/UAP56 and NXF1 are mutually exclusive. Interacts with SSRP1; required for its recruitment to mRNAs.By similarity1 Publication

Protein-protein interaction databases

BioGridⁱ	123976, 93 interactors
Database of interacting proteins More...DIPⁱ	DIP-62119N
IntActⁱ	Q96QD9, 18 interactors
Molecular INTeraction database More...MINTⁱ	Q96QD9
STRINGⁱ	9606.ENSP00000241502

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q96QD9
SMRⁱ	Q96QD9
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Motif

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Motifⁱ	26 – 44	UAP56-binding motifAdd BLAST		19

Sequence similaritiesⁱ

Belongs to the UIF family.Curated

Phylogenomic databases

eggNOGⁱ	ENOG410II12 Eukaryota ENOG4111TUX LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000012807
HOVERGENⁱ	HBG066549
InParanoidⁱ	Q96QD9
OMAⁱ	NQQKDTR
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0GRX
PhylomeDBⁱ	Q96QD9
TreeFamⁱ	TF336232

Family and domain databases

InterProⁱ	View protein in InterPro IPR009782 FYTTD1
PANTHERⁱ	PTHR21038 PTHR21038, 1 hit

Sequences (4+)ⁱ

Sequence statusⁱ: Complete.

This entry describes 4 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 4 described isoforms and 4 potential isoforms that are computationally mapped.Show all Align All

Isoform 1 (identifier: Q96QD9-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MNRFGTRLVG ATATSSPPPK ARSNENLDKI DMSLDDIIKL NRKEGKKQNF 
        60         70         80         90        100
PRLNRRLLQQ SGAQQFRMRV RWGIQQNSGF GKTSLNRRGR VMPGKRRPNG 
       110        120        130        140        150
VITGLAARKT TGIRKGISPM NRPPLSDKNI EQYFPVLKRK ANLLRQNEGQ 
       160        170        180        190        200
RKPVAVLKRP SQLSRKNNIP ANFTRSGNKL NHQKDTRQAT FLFRRGLKVQ 
       210        220        230        240        250
AQLNTEQLLD DVVAKRTRQW RTSTTNGGIL TVSIDNPGAV QCPVTQKPRL 
       260        270        280        290        300
TRTAVPSFLT KREQSDVKKV PKGVPLQFDI NSVGKQTGMT LNERFGILKE 
       310 
QRATLTYNKG GSRFVTVG

Length:318

Mass (Da):35,818

Last modified:January 19, 2010 - v3

Checksum:ⁱEB2F37D1D423D13C

GO

Isoform 2 (identifier: Q96QD9-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
1-35: MNRFGTRLVGATATSSPPPKARSNENLDKIDMSLD → MEPSVIMGN

« Hide

        10         20         30         40         50
MEPSVIMGND IIKLNRKEGK KQNFPRLNRR LLQQSGAQQF RMRVRWGIQQ 
        60         70         80         90        100
NSGFGKTSLN RRGRVMPGKR RPNGVITGLA ARKTTGIRKG ISPMNRPPLS 
       110        120        130        140        150
DKNIEQYFPV LKRKANLLRQ NEGQRKPVAV LKRPSQLSRK NNIPANFTRS 
       160        170        180        190        200
GNKLNHQKDT RQATFLFRRG LKVQAQLNTE QLLDDVVAKR TRQWRTSTTN 
       210        220        230        240        250
GGILTVSIDN PGAVQCPVTQ KPRLTRTAVP SFLTKREQSD VKKVPKGVPL 
       260        270        280        290 
QFDINSVGKQ TGMTLNERFG ILKEQRATLT YNKGGSRFVT VG

Note: No experimental confirmation available.

Show »

Length:292

Mass (Da):33,004

Checksum:ⁱE6E22D967F234F82

GO

Isoform 3 (identifier: Q96QD9-3) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
1-67: Missing.

« Hide

        10         20         30         40         50
MRVRWGIQQN SGFGKTSLNR RGRVMPGKRR PNGVITGLAA RKTTGIRKGI 
        60         70         80         90        100
SPMNRPPLSD KNIEQYFPVL KRKANLLRQN EGQRKPVAVL KRPSQLSRKN 
       110        120        130        140        150
NIPANFTRSG NKLNHQKDTR QATFLFRRGL KVQAQLNTEQ LLDDVVAKRT 
       160        170        180        190        200
RQWRTSTTNG GILTVSIDNP GAVQCPVTQK PRLTRTAVPS FLTKREQSDV 
       210        220        230        240        250
KKVPKGVPLQ FDINSVGKQT GMTLNERFGI LKEQRATLTY NKGGSRFVTV 

G

Note: No experimental confirmation available.

Show »

Length:251

Mass (Da):28,182

Checksum:ⁱ893BA69046662EA4

GO

Isoform 4 (identifier: Q96QD9-4) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
129-129: N → K
130-318: Missing.

« Hide

        10         20         30         40         50
MNRFGTRLVG ATATSSPPPK ARSNENLDKI DMSLDDIIKL NRKEGKKQNF 
        60         70         80         90        100
PRLNRRLLQQ SGAQQFRMRV RWGIQQNSGF GKTSLNRRGR VMPGKRRPNG 
       110        120 
VITGLAARKT TGIRKGISPM NRPPLSDKK

Note: No experimental confirmation available.

Show »

Length:129

Mass (Da):14,524

Checksum:ⁱDD28E3E18E6D18F9

GO

Computationally mapped potential isoform sequencesⁱ

There are 4 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

H9KVD1	H9KVD1_HUMAN	UAP56-interacting factor UAP56-interacting factor	FYTTD1	121	Annotation score:
H9KVC1	H9KVC1_HUMAN	UAP56-interacting factor UAP56-interacting factor	FYTTD1	71	Annotation score:
H9KVD5	H9KVD5_HUMAN	UAP56-interacting factor UAP56-interacting factor	FYTTD1	126	Annotation score:
H9KVC6	H9KVC6_HUMAN	UAP56-interacting factor UAP56-interacting factor	FYTTD1	176	Annotation score:

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	178	N → S in BAH14679 (PubMed:14702039).Curated		1
Sequence conflictⁱ	263	E → G in BAB55284 (PubMed:14702039).Curated		1

Natural variant

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Natural variantⁱVAR_062411	87	R → H4 PublicationsCorresponds to variant dbSNP:rs3205525Ensembl.		1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Length
Alternative sequenceⁱVSP_038658	1 – 67	Missing in isoform 3. 1 PublicationAdd BLAST	67
Alternative sequenceⁱVSP_038659	1 – 35	MNRFG…DMSLD → MEPSVIMGN in isoform 2. 1 PublicationAdd BLAST	35
Alternative sequenceⁱVSP_038660	129	N → K in isoform 4. 1 Publication	1
Alternative sequenceⁱVSP_038661	130 – 318	Missing in isoform 4. 1 PublicationAdd BLAST	189

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AJ344094 mRNA Translation: CAC51432.1 AL136558 mRNA Translation: CAB66493.1 AK027672 mRNA Translation: BAB55284.1 AK296283 mRNA Translation: BAH12300.1 AK302546 mRNA Translation: BAH13737.1 AK303462 mRNA Translation: BAH13966.1 AK315019 mRNA Translation: BAG37509.1 AK316308 mRNA Translation: BAH14679.1 CR533502 mRNA Translation: CAG38533.1 AC024560 Genomic DNA No translation available. AC055764 Genomic DNA No translation available. CH471252 Genomic DNA Translation: EAW92240.1 BC035006 mRNA Translation: AAH35006.1 BC039734 mRNA Translation: AAH39734.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS3329.1 [Q96QD9-1] CCDS43196.2 [Q96QD9-2]
NCBI Reference Sequences More...RefSeqⁱ	NP_001011537.2, NM_001011537.2 [Q96QD9-2] NP_115664.2, NM_032288.6 [Q96QD9-1]
UniGeneⁱ	Hs.277533

Genome annotation databases

Ensemblⁱ	ENST00000241502; ENSP00000241502; ENSG00000122068 [Q96QD9-1] ENST00000415708; ENSP00000393746; ENSG00000122068 [Q96QD9-2] ENST00000418169; ENSP00000400191; ENSG00000122068 [Q96QD9-4] ENST00000424384; ENSP00000394631; ENSG00000122068 [Q96QD9-3]
GeneIDⁱ	84248
KEGGⁱ	hsa:84248
UCSC genome browser More...UCSCⁱ	uc003fyi.3 human [Q96QD9-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing, Polymorphism

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q96QD9	Forty-two-three domain containing 1, isoform CRA_a		HUMAN		318	UniRef100_Q96QD9
FYTTD1 isoform 4		PANTR		318
Uncharacterized protein		PANPA		318
UAP56-interacting factor (Fragment)		HUMAN		176
FYTTD1 isoform 8		PANTR		251
+2
Q96QD9-4	FYTTD1 isoform 6		PANTR		129	UniRef100_A0A2J8JNC6

Protein	Similar proteins		Species	Score	Length	Source
Q96QD9	UAP56-interacting factor		BOVIN		318	UniRef90_Q96QD9
UAP56-interacting factor		MOUSE		317
UAP56-interacting factor		RAT		317
Forty-two-three domain containing 1, isoform CRA_a		HUMAN		318
FYTTD1 isoform 4		PANTR		318
+103
Q96QD9-2	UAP56-interacting factor (Fragment)		wild yak		294	UniRef90_Q96QD9-2
FYTTD1 isoform 3		PANTR		292
Uncharacterized protein		PANPA		292
Uncharacterized protein		MACMU		292
Uncharacterized protein		MANLE		286
+23
Q96QD9-4	FYTTD1 isoform 6		PANTR		129	UniRef90_A0A2J8JNC6
FYTTD1 isoform 6		PONAB		129

Protein	Similar proteins		Species	Score	Length	Source
Q96QD9	UAP56-interacting factor		BOVIN		318	UniRef50_Q96QD9
UAP56-interacting factor		MOUSE		317
UAP56-interacting factor		RAT		317
Forty-two-three domain containing 1, isoform CRA_a		HUMAN		318
FYTTD1 isoform 4		PANTR		318
+149
Q96QD9-4	UAP56-interacting factor		HUMAN		121	UniRef50_H9KVD1
FYTTD1 isoform 5		PANTR		121
FYTTD1 isoform 5		PONAB		121
FYTTD1 (Fragment)		CEREH		117
UAP56-interacting factor		MYOBR		137
+3

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AJ344094 mRNA Translation: CAC51432.1 AL136558 mRNA Translation: CAB66493.1 AK027672 mRNA Translation: BAB55284.1 AK296283 mRNA Translation: BAH12300.1 AK302546 mRNA Translation: BAH13737.1 AK303462 mRNA Translation: BAH13966.1 AK315019 mRNA Translation: BAG37509.1 AK316308 mRNA Translation: BAH14679.1 CR533502 mRNA Translation: CAG38533.1 AC024560 Genomic DNA No translation available. AC055764 Genomic DNA No translation available. CH471252 Genomic DNA Translation: EAW92240.1 BC035006 mRNA Translation: AAH35006.1 BC039734 mRNA Translation: AAH39734.1
CCDSⁱ	CCDS3329.1 [Q96QD9-1] CCDS43196.2 [Q96QD9-2]
RefSeqⁱ	NP_001011537.2, NM_001011537.2 [Q96QD9-2] NP_115664.2, NM_032288.6 [Q96QD9-1]
UniGeneⁱ	Hs.277533

3D structure databases

ProteinModelPortalⁱ	Q96QD9
SMRⁱ	Q96QD9
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	123976, 93 interactors
DIPⁱ	DIP-62119N
IntActⁱ	Q96QD9, 18 interactors
MINTⁱ	Q96QD9
STRINGⁱ	9606.ENSP00000241502

PTM databases

iPTMnetⁱ	Q96QD9
PhosphoSitePlusⁱ	Q96QD9

Polymorphism and mutation databases

BioMutaⁱ	FYTTD1
DMDMⁱ	284018159

Proteomic databases

EPDⁱ	Q96QD9
MaxQBⁱ	Q96QD9
PaxDbⁱ	Q96QD9
PeptideAtlasⁱ	Q96QD9
PRIDEⁱ	Q96QD9
ProteomicsDBⁱ	77857 77858 [Q96QD9-2] 77859 [Q96QD9-3] 77860 [Q96QD9-4]
TopDownProteomicsⁱ	Q96QD9-1 [Q96QD9-1]

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	84248
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000241502; ENSP00000241502; ENSG00000122068 [Q96QD9-1] ENST00000415708; ENSP00000393746; ENSG00000122068 [Q96QD9-2] ENST00000418169; ENSP00000400191; ENSG00000122068 [Q96QD9-4] ENST00000424384; ENSP00000394631; ENSG00000122068 [Q96QD9-3]
GeneIDⁱ	84248
KEGGⁱ	hsa:84248
UCSCⁱ	uc003fyi.3 human [Q96QD9-1]

Organism-specific databases

CTDⁱ	84248
EuPathDBⁱ	HostDB:ENSG00000122068.12
GeneCardsⁱ	FYTTD1
H-InvDBⁱ	HIX0003990
HGNCⁱ	HGNC:25407 FYTTD1
HPAⁱ	HPA054474
MIMⁱ	616933 gene
neXtProtⁱ	NX_Q96QD9
OpenTargetsⁱ	ENSG00000122068
PharmGKBⁱ	PA134946373
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	ENOG410II12 Eukaryota ENOG4111TUX LUCA
GeneTreeⁱ	ENSGT00390000012807
HOVERGENⁱ	HBG066549
InParanoidⁱ	Q96QD9
OMAⁱ	NQQKDTR
OrthoDBⁱ	EOG091G0GRX
PhylomeDBⁱ	Q96QD9
TreeFamⁱ	TF336232

Enzyme and pathway databases

Reactomeⁱ	R-HSA-109688 Cleavage of Growing Transcript in the Termination Region R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript R-HSA-72187 mRNA 3'-end processing

Reactomeⁱ

R-HSA-109688 Cleavage of Growing Transcript in the Termination Region
R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript
R-HSA-72187 mRNA 3'-end processing

Miscellaneous databases

ChiTaRSⁱ	FYTTD1 human
GenomeRNAiⁱ	84248
Protein Ontology More...PROⁱ	PR:Q96QD9
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000122068 Expressed in 205 organ(s), highest expression level in quadriceps femoris
CleanExⁱ	HS_FYTTD1
ExpressionAtlasⁱ	Q96QD9 baseline and differential
Genevisibleⁱ	Q96QD9 HS

Family and domain databases

InterProⁱ	View protein in InterPro IPR009782 FYTTD1
PANTHERⁱ	PTHR21038 PTHR21038, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	UIF_HUMAN
Accessionⁱ	Q96QD9Primary (citable) accession number: Q96QD9 Secondary accession number(s): A8MY74 Q9BQI8
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	May 15, 2007
	Last sequence update:	January 19, 2010
	Last modified:	September 12, 2018
	This is version 120 of the entry and version 3 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Human chromosome 3
Human chromosome 3: entries, gene names and cross-references to MIM
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

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UniProtKB - Q96QD9 (UIF_HUMAN)

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UAP56-interacting factor

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Nucleus

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Motif

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Experimental Info

Natural variant

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ