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Entry version 126 (22 Apr 2020)
Sequence version 2 (11 Jan 2011)
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Protein

Proline-rich acidic protein 1

Gene

PRAP1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May play an important role in maintaining normal growth homeostasis in epithelial cells.1 Publication

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Proline-rich acidic protein 1
Alternative name(s):
Epididymis tissue protein Li 178
Uterine-specific proline-rich acidic protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PRAP1
Synonyms:UPA
ORF Names:UNQ608/PRO1195
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:23304 PRAP1

Online Mendelian Inheritance in Man (OMIM)

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MIMi
609776 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q96NZ9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
118471

Open Targets

More...
OpenTargetsi
ENSG00000165828

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134981678

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q96NZ9 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
PRAP1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
317373269

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 20Sequence analysisAdd BLAST20
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000029941621 – 151Proline-rich acidic protein 1Add BLAST131

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q96NZ9

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q96NZ9

PeptideAtlas

More...
PeptideAtlasi
Q96NZ9

PRoteomics IDEntifications database

More...
PRIDEi
Q96NZ9

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
77583 [Q96NZ9-1]
77584 [Q96NZ9-2]
77585 [Q96NZ9-3]
77586 [Q96NZ9-4]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q96NZ9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q96NZ9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Abundantly expressed in the epithelial cells of the liver, kidney, gastrointestinal tract and cervix. Significantly down-regulated in hepatocellular carcinoma and right colon adenocarcinoma compared with the respective adjacent normal tissues. Expressed in epididymis (at protein level).2 Publications

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Up-regulated by butyrate, trichostatin A and 5'-aza-2' deoxycytidine.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000165828 Expressed in duodenum and 98 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q96NZ9 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q96NZ9 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000165828 Group enriched (intestine, liver)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Show more details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
125610, 8 interactors

Protein interaction database and analysis system

More...
IntActi
Q96NZ9, 16 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000416126

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q96NZ9 protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410J3WZ Eukaryota
ENOG4111CMU LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000012626

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q96NZ9

KEGG Orthology (KO)

More...
KOi
K21250

Database of Orthologous Groups

More...
OrthoDBi
1574174at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q96NZ9

TreeFam database of animal gene trees

More...
TreeFami
TF337049

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR027922 PRAP

The PANTHER Classification System

More...
PANTHERi
PTHR37861 PTHR37861, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15314 PRAP, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 4 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q96NZ9-1) [UniParc]FASTAAdd to basket
Also known as: PRAP

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MRRLLLVTSL VVVLLWEAGA VPAPKVPIKM QVKHWPSEQD PEKAWGARVV
60 70 80 90 100
EPPEKDDQLV VLFPVQKPKL LTTEEKPRGQ GRGPILPGTK AWMETEDTLG
110 120 130 140 150
HVLSPEPDHD SLYHPPPEED QGEERPRLWV MPNHQVLLGP EEDQDHIYHP

Q
Length:151
Mass (Da):17,208
Last modified:January 11, 2011 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB751EDBFD24D08CA
GO
Isoform 2 (identifier: Q96NZ9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     79-87: Missing.
     95-151: TEDTLGHVLSPEPDHDSLYHPPPEEDQGEERPRLWVMPNHQVLLGPEEDQDHIYHPQ → SRARP

Show »
Length:90
Mass (Da):10,259
Checksum:iE8C3C22D12F8E9CC
GO
Isoform 3 (identifier: Q96NZ9-3) [UniParc]FASTAAdd to basket
Also known as: PRAPV1

The sequence of this isoform differs from the canonical sequence as follows:
     43-43: K → NR

Show »
Length:152
Mass (Da):17,350
Checksum:i026C7D3AE8C988E1
GO
Isoform 4 (identifier: Q96NZ9-4) [UniParc]FASTAAdd to basket
Also known as: PRAPV2

The sequence of this isoform differs from the canonical sequence as follows:
     79-87: Missing.

Show »
Length:142
Mass (Da):16,332
Checksum:i149282D65B6346E6
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAP97247 differs from that shown. Reason: Frameshift.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_03481554E → G1 Publication1
Natural variantiVAR_03481669K → R1 Publication1
Natural variantiVAR_03481781G → S. Corresponds to variant dbSNP:rs34780987Ensembl.1
Natural variantiVAR_034818101H → R6 PublicationsCorresponds to variant dbSNP:rs4369319Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_02766043K → NR in isoform 3. 1 Publication1
Alternative sequenceiVSP_02766179 – 87Missing in isoform 2 and isoform 4. 2 Publications9
Alternative sequenceiVSP_02766295 – 151TEDTL…IYHPQ → SRARP in isoform 2. 1 PublicationAdd BLAST57

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF421885 mRNA Translation: AAL16670.1
AY158074 mRNA Translation: AAN87018.1
AF123768 mRNA Translation: AAP97247.1 Frameshift.
AY358908 mRNA Translation: AAQ89267.1
GU727628 mRNA Translation: ADU87630.1
AL360181 Genomic DNA No translation available.
CH471211 Genomic DNA Translation: EAW61336.1
BC029447 mRNA Translation: AAH29447.2
BC061643 mRNA Translation: AAH61643.1
BC071872 mRNA Translation: AAH71872.1
BC093853 mRNA Translation: AAH93853.1
BC101743 mRNA Translation: AAI01744.1
BC143590 mRNA Translation: AAI43591.1
BC143592 mRNA Translation: AAI43593.1
BC143591 mRNA Translation: AAI43592.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS44498.1 [Q96NZ9-4]
CCDS7679.1 [Q96NZ9-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001138673.1, NM_001145201.1 [Q96NZ9-4]
NP_660203.3, NM_145202.4 [Q96NZ9-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000433452; ENSP00000416126; ENSG00000165828 [Q96NZ9-1]
ENST00000463201; ENSP00000486265; ENSG00000165828 [Q96NZ9-4]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
118471

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:118471

UCSC genome browser

More...
UCSCi
uc001lmp.3 human [Q96NZ9-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF421885 mRNA Translation: AAL16670.1
AY158074 mRNA Translation: AAN87018.1
AF123768 mRNA Translation: AAP97247.1 Frameshift.
AY358908 mRNA Translation: AAQ89267.1
GU727628 mRNA Translation: ADU87630.1
AL360181 Genomic DNA No translation available.
CH471211 Genomic DNA Translation: EAW61336.1
BC029447 mRNA Translation: AAH29447.2
BC061643 mRNA Translation: AAH61643.1
BC071872 mRNA Translation: AAH71872.1
BC093853 mRNA Translation: AAH93853.1
BC101743 mRNA Translation: AAI01744.1
BC143590 mRNA Translation: AAI43591.1
BC143592 mRNA Translation: AAI43593.1
BC143591 mRNA Translation: AAI43592.1
CCDSiCCDS44498.1 [Q96NZ9-4]
CCDS7679.1 [Q96NZ9-1]
RefSeqiNP_001138673.1, NM_001145201.1 [Q96NZ9-4]
NP_660203.3, NM_145202.4 [Q96NZ9-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi125610, 8 interactors
IntActiQ96NZ9, 16 interactors
STRINGi9606.ENSP00000416126

PTM databases

iPTMnetiQ96NZ9
PhosphoSitePlusiQ96NZ9

Polymorphism and mutation databases

BioMutaiPRAP1
DMDMi317373269

Proteomic databases

MassIVEiQ96NZ9
PaxDbiQ96NZ9
PeptideAtlasiQ96NZ9
PRIDEiQ96NZ9
ProteomicsDBi77583 [Q96NZ9-1]
77584 [Q96NZ9-2]
77585 [Q96NZ9-3]
77586 [Q96NZ9-4]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
48788 62 antibodies

The DNASU plasmid repository

More...
DNASUi
118471

Genome annotation databases

EnsembliENST00000433452; ENSP00000416126; ENSG00000165828 [Q96NZ9-1]
ENST00000463201; ENSP00000486265; ENSG00000165828 [Q96NZ9-4]
GeneIDi118471
KEGGihsa:118471
UCSCiuc001lmp.3 human [Q96NZ9-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
118471
DisGeNETi118471

GeneCards: human genes, protein and diseases

More...
GeneCardsi
PRAP1
HGNCiHGNC:23304 PRAP1
HPAiENSG00000165828 Group enriched (intestine, liver)
MIMi609776 gene
neXtProtiNX_Q96NZ9
OpenTargetsiENSG00000165828
PharmGKBiPA134981678

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410J3WZ Eukaryota
ENOG4111CMU LUCA
GeneTreeiENSGT00390000012626
InParanoidiQ96NZ9
KOiK21250
OrthoDBi1574174at2759
PhylomeDBiQ96NZ9
TreeFamiTF337049

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
PRAP1 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
118471
PharosiQ96NZ9 Tdark

Protein Ontology

More...
PROi
PR:Q96NZ9
RNActiQ96NZ9 protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000165828 Expressed in duodenum and 98 other tissues
ExpressionAtlasiQ96NZ9 baseline and differential
GenevisibleiQ96NZ9 HS

Family and domain databases

InterProiView protein in InterPro
IPR027922 PRAP
PANTHERiPTHR37861 PTHR37861, 1 hit
PfamiView protein in Pfam
PF15314 PRAP, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPRAP1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96NZ9
Secondary accession number(s): B7ZL57
, B7ZL58, E9KL31, Q5VWY4, Q7Z4X5, Q8IWR3, Q8NCS2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: January 11, 2011
Last modified: April 22, 2020
This is version 126 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
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