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Protein

Sodium channel and clathrin linker 1

Gene

SCLT1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Adapter protein that links SCN10A to clathrin. Regulates SCN10A channel activity, possibly by promoting channel internalization (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

  • ciliary basal body-plasma membrane docking Source: Reactome
  • cilium assembly Source: UniProtKB
  • clustering of voltage-gated sodium channels Source: Ensembl

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-5620912 Anchoring of the basal body to the plasma membrane

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Sodium channel and clathrin linker 1
Alternative name(s):
Sodium channel-associated protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SCLT1
Synonyms:SAP1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000151466.11

Human Gene Nomenclature Database

More...
HGNCi
HGNC:26406 SCLT1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
611399 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q96NL6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
132320

Open Targets

More...
OpenTargetsi
ENSG00000151466

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA147357369

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
SCLT1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
300669665

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedCombined sources
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003171272 – 688Sodium channel and clathrin linker 1Add BLAST687

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylalanineCombined sources1
Modified residuei681PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q96NL6

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q96NL6

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q96NL6

PeptideAtlas

More...
PeptideAtlasi
Q96NL6

PRoteomics IDEntifications database

More...
PRIDEi
Q96NL6

ProteomicsDB human proteome resource

More...
ProteomicsDBi
77532
77533 [Q96NL6-2]
77534 [Q96NL6-3]
77535 [Q96NL6-4]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q96NL6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q96NL6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000151466 Expressed in 165 organ(s), highest expression level in buccal mucosa cell

CleanEx database of gene expression profiles

More...
CleanExi
HS_SCLT1

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q96NL6 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q96NL6 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA036560
HPA036561

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with SCN10A and clathrin. Identified in a complex containing SCN10A, clathrin and SCLT1 (By similarity).By similarity

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
126318, 161 interactors

Protein interaction database and analysis system

More...
IntActi
Q96NL6, 159 interactors

Molecular INTeraction database

More...
MINTi
Q96NL6

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000281142

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q96NL6

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q96NL6

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili69 – 673Sequence analysisAdd BLAST605

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IE5K Eukaryota
ENOG4111QZJ LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00730000111168

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000154268

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG098335

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q96NL6

Identification of Orthologs from Complete Genome Data

More...
OMAi
CGFVSEQ

Database of Orthologous Groups

More...
OrthoDBi
EOG091G03T6

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q96NL6

TreeFam database of animal gene trees

More...
TreeFami
TF331372

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR038911 SCLT1

The PANTHER Classification System

More...
PANTHERi
PTHR35970 PTHR35970, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q96NL6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAAEIDFLRE QNRRLNEDFR RYQMESFSKY SSVQKAVCQG EGDDTFENLV
60 70 80 90 100
FDQSFLAPLV TEYDKHLGEL NGQLKYYQKQ VGEMKLQLEN VIKENERLHS
110 120 130 140 150
ELKDAVEKKL EAFPLGTEVG TDIYADDETV RNLQEQLQLA NQEKTQAVEL
160 170 180 190 200
WQTVSQELDR LHKLYQEHMT EAQIHVFESQ KQKDQLFDFQ QLTKQLHVTN
210 220 230 240 250
ENMEVTNQQF LKTVTEQSVI IEQLRKKLRQ AKLELRVAVA KVEELTNVTE
260 270 280 290 300
DLQGQMKKKE KDVVSAHGRE EASDRRLQQL QSSIKQLEIR LCVTIQEANQ
310 320 330 340 350
LRTENTHLEK QTRELQAKCN ELENERYEAI VRARNSMQLL EEANLQKSQA
360 370 380 390 400
LLEEKQKEED IEKMKETVSR FVQDATIRTK KEVANTKKQC NIQISRLTEE
410 420 430 440 450
LSALQMECAE KQGQIERVIK EKKAVEEELE KIYREGRGNE SDYRKLEEMH
460 470 480 490 500
QRFLVSERSK DDLQLRLTRA ENRIKQLETD SSEEISRYQE MIQKLQNVLE
510 520 530 540 550
SERENCGLVS EQRLKLQQEN KQLRKETESL RKIALEAQKK AKVKISTMEH
560 570 580 590 600
EFSIKERGFE VQLREMEDSN RNSIVELRHL LATQQKAANR WKEETKKLTE
610 620 630 640 650
SAEIRINNLK SELSRQKLHT QELLSQLEMA NEKVAENEKL ILEHQEKANR
660 670 680
LQRRLSQAEE RAASASQQLS VITVQRRKAA SLMNLENI
Length:688
Mass (Da):80,910
Last modified:July 13, 2010 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9432F258529C47D3
GO
Isoform 2 (identifier: Q96NL6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     230-610: Missing.

Note: No experimental confirmation available.
Show »
Length:307
Mass (Da):36,042
Checksum:i4587B760E26E200D
GO
Isoform 3 (identifier: Q96NL6-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     98-610: Missing.

Note: No experimental confirmation available.
Show »
Length:175
Mass (Da):20,468
Checksum:i282CB741C90CFC0A
GO
Isoform 4 (identifier: Q96NL6-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     79-79: K → A
     80-688: Missing.

Note: No experimental confirmation available.
Show »
Length:79
Mass (Da):9,323
Checksum:iED2C20AEE54627E8
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D6RBA6D6RBA6_HUMAN
Sodium channel and clathrin linker ...
SCLT1
131Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RBP0D6RBP0_HUMAN
Sodium channel and clathrin linker ...
SCLT1
284Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D6RDM2D6RDM2_HUMAN
Sodium channel and clathrin linker ...
SCLT1
56Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_038481441S → C2 PublicationsCorresponds to variant dbSNP:rs10028124Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_03090479K → A in isoform 4. 1 Publication1
Alternative sequenceiVSP_03090580 – 688Missing in isoform 4. 1 PublicationAdd BLAST609
Alternative sequenceiVSP_03090698 – 610Missing in isoform 3. 1 PublicationAdd BLAST513
Alternative sequenceiVSP_030907230 – 610Missing in isoform 2. 1 PublicationAdd BLAST381

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK055217 mRNA Translation: BAB70876.1
AC093783 Genomic DNA No translation available.
AC093826 Genomic DNA No translation available.
CH471056 Genomic DNA Translation: EAX05167.1
BC064428 mRNA Translation: AAH64428.1
BC121057 mRNA Translation: AAI21058.1
BC121058 mRNA Translation: AAI21059.1
BC128051 mRNA Translation: AAI28052.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS3740.1 [Q96NL6-1]
CCDS77958.1 [Q96NL6-4]

NCBI Reference Sequences

More...
RefSeqi
NP_001287826.1, NM_001300897.1 [Q96NL6-4]
NP_001287827.1, NM_001300898.1
NP_653244.2, NM_144643.3 [Q96NL6-1]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.654690

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000281142; ENSP00000281142; ENSG00000151466 [Q96NL6-1]
ENST00000439369; ENSP00000395292; ENSG00000151466 [Q96NL6-3]
ENST00000511426; ENSP00000420861; ENSG00000151466 [Q96NL6-4]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
132320

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:132320

UCSC genome browser

More...
UCSCi
uc003igp.3 human [Q96NL6-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK055217 mRNA Translation: BAB70876.1
AC093783 Genomic DNA No translation available.
AC093826 Genomic DNA No translation available.
CH471056 Genomic DNA Translation: EAX05167.1
BC064428 mRNA Translation: AAH64428.1
BC121057 mRNA Translation: AAI21058.1
BC121058 mRNA Translation: AAI21059.1
BC128051 mRNA Translation: AAI28052.1
CCDSiCCDS3740.1 [Q96NL6-1]
CCDS77958.1 [Q96NL6-4]
RefSeqiNP_001287826.1, NM_001300897.1 [Q96NL6-4]
NP_001287827.1, NM_001300898.1
NP_653244.2, NM_144643.3 [Q96NL6-1]
UniGeneiHs.654690

3D structure databases

ProteinModelPortaliQ96NL6
SMRiQ96NL6
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi126318, 161 interactors
IntActiQ96NL6, 159 interactors
MINTiQ96NL6
STRINGi9606.ENSP00000281142

PTM databases

iPTMnetiQ96NL6
PhosphoSitePlusiQ96NL6

Polymorphism and mutation databases

BioMutaiSCLT1
DMDMi300669665

Proteomic databases

EPDiQ96NL6
MaxQBiQ96NL6
PaxDbiQ96NL6
PeptideAtlasiQ96NL6
PRIDEiQ96NL6
ProteomicsDBi77532
77533 [Q96NL6-2]
77534 [Q96NL6-3]
77535 [Q96NL6-4]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000281142; ENSP00000281142; ENSG00000151466 [Q96NL6-1]
ENST00000439369; ENSP00000395292; ENSG00000151466 [Q96NL6-3]
ENST00000511426; ENSP00000420861; ENSG00000151466 [Q96NL6-4]
GeneIDi132320
KEGGihsa:132320
UCSCiuc003igp.3 human [Q96NL6-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
132320
DisGeNETi132320
EuPathDBiHostDB:ENSG00000151466.11

GeneCards: human genes, protein and diseases

More...
GeneCardsi
SCLT1

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0004499
HGNCiHGNC:26406 SCLT1
HPAiHPA036560
HPA036561
MIMi611399 gene
neXtProtiNX_Q96NL6
OpenTargetsiENSG00000151466
PharmGKBiPA147357369

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IE5K Eukaryota
ENOG4111QZJ LUCA
GeneTreeiENSGT00730000111168
HOGENOMiHOG000154268
HOVERGENiHBG098335
InParanoidiQ96NL6
OMAiCGFVSEQ
OrthoDBiEOG091G03T6
PhylomeDBiQ96NL6
TreeFamiTF331372

Enzyme and pathway databases

ReactomeiR-HSA-5620912 Anchoring of the basal body to the plasma membrane

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
SCLT1 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
132320

Protein Ontology

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PROi
PR:Q96NL6

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000151466 Expressed in 165 organ(s), highest expression level in buccal mucosa cell
CleanExiHS_SCLT1
ExpressionAtlasiQ96NL6 baseline and differential
GenevisibleiQ96NL6 HS

Family and domain databases

InterProiView protein in InterPro
IPR038911 SCLT1
PANTHERiPTHR35970 PTHR35970, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSCLT1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96NL6
Secondary accession number(s): A4QN04, Q0VAH2, Q6P2M4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: July 13, 2010
Last modified: November 7, 2018
This is version 122 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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