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UniProtKB - Q96NJ3 (ZN285_HUMAN)

Entry version 159 (02 Jun 2021)
Sequence version 2 (16 Jun 2009)
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Protein

Zinc finger protein 285

Gene

ZNF285

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri232 – 254C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri260 – 282C2H2-type 2; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri316 – 338C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri344 – 366C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri372 – 394C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri400 – 422C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri428 – 450C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri456 – 478C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri484 – 506C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri512 – 534C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri540 – 562C2H2-type 11PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q96NJ3

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-212436, Generic Transcription Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 285
Alternative name(s):
Zinc finger protein 285A
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF285
Synonyms:ZNF285A
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:13079, ZNF285

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q96NJ3

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000267508.5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		26974

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA165394833

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q96NJ3, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ZNF285

Domain mapping of disease mutations (DMDM)

More...DMDMi		239938813

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003781061 – 590Zinc finger protein 285Add BLAST590

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q96NJ3

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q96NJ3

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q96NJ3

PeptideAtlas

More...PeptideAtlasi		Q96NJ3

PRoteomics IDEntifications database

More...PRIDEi		Q96NJ3

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		77520 [Q96NJ3-1]
77521 [Q96NJ3-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q96NJ3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q96NJ3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000267508, Expressed in secondary oocyte and 173 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q96NJ3, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q96NJ3, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000267508, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		117930, 1 interactor

Protein interaction database and analysis system

More...IntActi		Q96NJ3, 3 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000464788

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q96NJ3, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q96NJ3

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini8 – 86KRABPROSITE-ProRule annotationAdd BLAST79

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the krueppel C2H2-type zinc-finger protein family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri232 – 254C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri260 – 282C2H2-type 2; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri316 – 338C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri344 – 366C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri372 – 394C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri400 – 422C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri428 – 450C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri456 – 478C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri484 – 506C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri512 – 534C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri540 – 562C2H2-type 11PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1721, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_002678_0_2_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q96NJ3

Database of Orthologous Groups

More...OrthoDBi		1318335at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q96NJ3

TreeFam database of animal gene trees

More...TreeFami		TF350845

Family and domain databases

Conserved Domains Database

More...CDDi		cd07765, KRAB_A-box, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR001909, KRAB
IPR036051, KRAB_dom_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01352, KRAB, 1 hit
PF00096, zf-C2H2, 9 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00349, KRAB, 1 hit
SM00355, ZnF_C2H2, 11 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF109640, SSF109640, 1 hit
SSF57667, SSF57667, 6 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50805, KRAB, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 10 hits
PS50157, ZINC_FINGER_C2H2_2, 11 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q96NJ3-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MIKFQERVTF KDVAVVFTKE ELALLDKAQI NLYQDVMLEN FRNLMLVRDG 
        60         70         80         90        100
IKNNILNLQA KGLSYLSQEV LHCWQIWKQR IRDLTVSQDY IVNLQEECSP 
       110        120        130        140        150
HLEDVSLSEE WAGISLQISE NENYVVNAII KNQDITAWQS LTQVLTPESW 
       160        170        180        190        200
RKANIMTEPQ NSQGRYKGIY MEEKLYRRAQ HDDSLSWTSC DHHESQECKG 
       210        220        230        240        250
EDPGRHPNCG KNLGMKSTVE KRNAAHVLPQ PFPCNNCGVA FADDTDPHVH 
       260        270        280        290        300
HSTHLGEKSY KCDQYGKNFS QSQDLIVHCK THSGKTPYEF HEWPMGCKQS 
       310        320        330        340        350
SDLPRYQKVS SGDKPYKCKE CGKGFRRSSS LHNHHRVHTG EMPYKCDECG 
       360        370        380        390        400
KGFGFRSLLC IHQGVHTGKK PYKCEECGKG FDQSSNLLVH QRVHTGEKPY 
       410        420        430        440        450
KCSECGKCFS SSSVLQVHWR FHTGEKPYRC GECGKGFSQC THLHIHQRVH 
       460        470        480        490        500
TGEKPYKCNV CGKDFAYSSV LHTHQRVHTG EKPYKCEVCG KCFSYSSYFH 
       510        520        530        540        550
LHQRDHIREK PYKCDECGKG FSRNSDLNVH LRVHTRERPY KCKACGKGFS 
       560        570        580        590
RNSYLLAHQR VHIDETQYTH CERGKDLLTH QRLHEQRETL
Length:590
Mass (Da):68,261
Last modified:June 16, 2009 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0A3F51DEE2396462
GO
Isoform 2 (identifier: Q96NJ3-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-155: Missing.

Show »
Length:435
Mass (Da):50,168
Checksum:iB7845B029FCE167C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
K7EIK6K7EIK6_HUMAN
Zinc finger protein 285
ZNF285
597Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EQE9K7EQE9_HUMAN
Zinc finger protein 285
ZNF285
56Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7ERT5K7ERT5_HUMAN
Zinc finger protein 285
ZNF285
39Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_057972208N → S2 PublicationsCorresponds to variant dbSNP:rs2571089Ensembl.1
Natural variantiVAR_057973536R → G2 PublicationsCorresponds to variant dbSNP:rs12610859Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0375021 – 155Missing in isoform 2. 2 PublicationsAdd BLAST155

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK055309 mRNA Translation: BAB70901.1
AC138473 Genomic DNA No translation available.
BC117300 mRNA Translation: AAI17301.1
BC117302 mRNA Translation: AAI17303.1
BC069384 mRNA Translation: AAH69384.2
BC074875 mRNA Translation: AAH74875.2

The Consensus CDS (CCDS) project

More...CCDSi		CCDS12638.1 [Q96NJ3-1]

NCBI Reference Sequences

More...RefSeqi		NP_001278417.1, NM_001291488.1
NP_001278418.1, NM_001291489.1
NP_001278419.1, NM_001291490.1
NP_001278420.1, NM_001291491.1
NP_689567.4, NM_152354.5

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000544719; ENSP00000439431; ENSG00000267508
ENST00000614994; ENSP00000483662; ENSG00000267508

Database of genes from NCBI RefSeq genomes

More...GeneIDi		26974

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:26974

UCSC genome browser

More...UCSCi		uc002ozd.5, human [Q96NJ3-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK055309 mRNA Translation: BAB70901.1
AC138473 Genomic DNA No translation available.
BC117300 mRNA Translation: AAI17301.1
BC117302 mRNA Translation: AAI17303.1
BC069384 mRNA Translation: AAH69384.2
BC074875 mRNA Translation: AAH74875.2
CCDSiCCDS12638.1 [Q96NJ3-1]
RefSeqiNP_001278417.1, NM_001291488.1
NP_001278418.1, NM_001291489.1
NP_001278419.1, NM_001291490.1
NP_001278420.1, NM_001291491.1
NP_689567.4, NM_152354.5

3D structure databases

SMRiQ96NJ3
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi117930, 1 interactor
IntActiQ96NJ3, 3 interactors
STRINGi9606.ENSP00000464788

PTM databases

iPTMnetiQ96NJ3
PhosphoSitePlusiQ96NJ3

Genetic variation databases

BioMutaiZNF285
DMDMi239938813

Proteomic databases

jPOSTiQ96NJ3
MassIVEiQ96NJ3
PaxDbiQ96NJ3
PeptideAtlasiQ96NJ3
PRIDEiQ96NJ3
ProteomicsDBi77520 [Q96NJ3-1]
77521 [Q96NJ3-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		65032, 62 antibodies

The DNASU plasmid repository

More...DNASUi		26974

Genome annotation databases

EnsembliENST00000544719; ENSP00000439431; ENSG00000267508
ENST00000614994; ENSP00000483662; ENSG00000267508
GeneIDi26974
KEGGihsa:26974
UCSCiuc002ozd.5, human [Q96NJ3-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		26974
DisGeNETi26974

GeneCards: human genes, protein and diseases

More...GeneCardsi		ZNF285
HGNCiHGNC:13079, ZNF285
HPAiENSG00000267508, Low tissue specificity
neXtProtiNX_Q96NJ3
PharmGKBiPA165394833
VEuPathDBiHostDB:ENSG00000267508.5

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
HOGENOMiCLU_002678_0_2_1
InParanoidiQ96NJ3
OrthoDBi1318335at2759
PhylomeDBiQ96NJ3
TreeFamiTF350845

Enzyme and pathway databases

PathwayCommonsiQ96NJ3
ReactomeiR-HSA-212436, Generic Transcription Pathway

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		26974, 121 hits in 970 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		26974
PharosiQ96NJ3, Tdark

Protein Ontology

More...PROi		PR:Q96NJ3
RNActiQ96NJ3, protein

Gene expression databases

BgeeiENSG00000267508, Expressed in secondary oocyte and 173 other tissues
ExpressionAtlasiQ96NJ3, baseline and differential
GenevisibleiQ96NJ3, HS

Family and domain databases

CDDicd07765, KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909, KRAB
IPR036051, KRAB_dom_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF01352, KRAB, 1 hit
PF00096, zf-C2H2, 9 hits
SMARTiView protein in SMART
SM00349, KRAB, 1 hit
SM00355, ZnF_C2H2, 11 hits
SUPFAMiSSF109640, SSF109640, 1 hit
SSF57667, SSF57667, 6 hits
PROSITEiView protein in PROSITE
PS50805, KRAB, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 10 hits
PS50157, ZINC_FINGER_C2H2_2, 11 hits

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN285_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96NJ3
Secondary accession number(s): Q17RJ3, Q6B0A8, Q6ISR5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 23, 2004
Last sequence update: June 16, 2009
Last modified: June 2, 2021
This is version 159 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. SIMILARITY comments
    Index of protein domains and families
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