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Protein

Zinc finger protein 582

Gene

ZNF582

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri171 – 193C2H2-type 1; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri199 – 221C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri227 – 249C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri255 – 277C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri283 – 305C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri311 – 333C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri339 – 361C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri367 – 389C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri395 – 417C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri423 – 445C2H2-type 10PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-212436 Generic Transcription Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 582
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF582
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000018869.16

Human Gene Nomenclature Database

More...
HGNCi
HGNC:26421 ZNF582

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
615600 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q96NG8

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
147948

Open Targets

More...
OpenTargetsi
ENSG00000018869

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134989661

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF582

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74732564

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002345911 – 517Zinc finger protein 582Add BLAST517

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q96NG8

PeptideAtlas

More...
PeptideAtlasi
Q96NG8

PRoteomics IDEntifications database

More...
PRIDEi
Q96NG8

ProteomicsDB human proteome resource

More...
ProteomicsDBi
77511

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q96NG8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q96NG8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000018869 Expressed in 141 organ(s), highest expression level in gastrocnemius

CleanEx database of gene expression profiles

More...
CleanExi
HS_ZNF582

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q96NG8 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q96NG8 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA028858

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
127104, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000301310

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q96NG8

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q96NG8

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini6 – 77KRABPROSITE-ProRule annotationAdd BLAST72

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri171 – 193C2H2-type 1; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri199 – 221C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri227 – 249C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri255 – 277C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri283 – 305C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri311 – 333C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri339 – 361C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri367 – 389C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri395 – 417C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri423 – 445C2H2-type 10PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721 Eukaryota
COG5048 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000162794

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000234617

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG018163

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q96NG8

KEGG Orthology (KO)

More...
KOi
K09228

Identification of Orthologs from Complete Genome Data

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OMAi
RKDFWQE

Database of Orthologous Groups

More...
OrthoDBi
EOG091G02KC

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q96NG8

TreeFam database of animal gene trees

More...
TreeFami
TF337055

Family and domain databases

Conserved Domains Database

More...
CDDi
cd07765 KRAB_A-box, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 9 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 9 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 6 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 9 hits
PS50157 ZINC_FINGER_C2H2_2, 10 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

Q96NG8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSLGSELFRD VAIVFSQEEW QWLAPAQRDL YRDVMLETYS NLVSLGLAVS
60 70 80 90 100
KPDVISFLEQ GKEPWMVERV VSGGLCPVLE SRYDTKELFP KQHVYEVESP
110 120 130 140 150
QWEIMESLTS YGLECSSFQD DWECRNQFDR QQGNPDRHFH QMIIRHEEMP
160 170 180 190 200
TFDQHASLTF YQKIHTREKP FGYNKCRKDF WQKELLINHQ GIYTNEKPYK
210 220 230 240 250
CKECGKAFKY GSRLIQHENI HSGKKPYECK ECGKAFNSGS NFIQHQRVHT
260 270 280 290 300
GEKPYECKDC EKAFSRSSQL IEHQRTHTGE KPYQCKECGK AFNRISHLKV
310 320 330 340 350
HYRIHTGEKP YACKECGKTF SHRSQLIQHQ TVHTGRKLYE CKECGKAFNQ
360 370 380 390 400
GSTLIRHQRI HTGEKPYECK VCGKAFRVSS QLKQHQRIHT GEKPYQCKVC
410 420 430 440 450
GRAFKRVSHL TVHYRIHTGE KPYECKECGK AFSHCSQLIH HQVIHTEKKP
460 470 480 490 500
YEYKECEKTL SHDSTTVQPQ RMHNRETHVN IINVEKPSIS SYPLLIIREF
510
MLASNHMNGS NGESPLA
Length:517
Mass (Da):60,498
Last modified:December 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFEE3AE28C6F8B53A
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A075B772A0A075B772_HUMAN
Zinc finger protein 582
ZNF582
181Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EKI7K7EKI7_HUMAN
Zinc finger protein 582
ZNF582
78Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7ESE7K7ESE7_HUMAN
Zinc finger protein 582
ZNF582
103Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A075B771A0A075B771_HUMAN
Zinc finger protein 582
ZNF582
178Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH11796 differs from that shown. Contaminating sequence. Potential poly-A sequence.Curated
The sequence BAG61111 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence BAH14399 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence EAW72447 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti286K → R in BAH14399 (PubMed:14702039).Curated1
Sequence conflicti365K → R in BAH14399 (PubMed:14702039).Curated1
Sequence conflicti411T → A in BAH14399 (PubMed:14702039).Curated1
Sequence conflicti426K → G in BAH14399 (PubMed:14702039).Curated1
Sequence conflicti475R → G in BAH14399 (PubMed:14702039).Curated1
Sequence conflicti487P → A in BAH14399 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_07055765W → G Found in a patient with mild intellectual disability and eye movement disorder; unknown pathological significance. 1 PublicationCorresponds to variant dbSNP:rs369155373Ensembl.1
Natural variantiVAR_03357869R → T. Corresponds to variant dbSNP:rs11883260Ensembl.1
Natural variantiVAR_070558345G → E Found in a patient with mild intellectual disability and eye movement disorder; unknown pathological significance. 1 PublicationCorresponds to variant dbSNP:rs149022328Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK055489 mRNA Translation: BAB70931.1
AK299036 mRNA Translation: BAG61111.1 Different initiation.
AK316028 mRNA Translation: BAH14399.1 Different initiation.
CH471135 Genomic DNA Translation: EAW72447.1 Sequence problems.
BC011796 mRNA Translation: AAH11796.1 Sequence problems.
BC101008 mRNA Translation: AAI01009.1
BC101009 mRNA Translation: AAI01010.1
BC101010 mRNA Translation: AAI01011.1
BC101011 mRNA Translation: AAI01012.1

The Consensus CDS (CCDS) project

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CCDSi
CCDS33121.1

NCBI Reference Sequences

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RefSeqi
NP_001307300.1, NM_001320371.1
NP_653291.1, NM_144690.2

UniGene gene-oriented nucleotide sequence clusters

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UniGenei
Hs.244391
Hs.655905

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000301310; ENSP00000301310; ENSG00000018869
ENST00000586929; ENSP00000465619; ENSG00000018869
ENST00000619584; ENSP00000483414; ENSG00000018869

Database of genes from NCBI RefSeq genomes

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GeneIDi
147948

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:147948

UCSC genome browser

More...
UCSCi
uc002qmz.1 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK055489 mRNA Translation: BAB70931.1
AK299036 mRNA Translation: BAG61111.1 Different initiation.
AK316028 mRNA Translation: BAH14399.1 Different initiation.
CH471135 Genomic DNA Translation: EAW72447.1 Sequence problems.
BC011796 mRNA Translation: AAH11796.1 Sequence problems.
BC101008 mRNA Translation: AAI01009.1
BC101009 mRNA Translation: AAI01010.1
BC101010 mRNA Translation: AAI01011.1
BC101011 mRNA Translation: AAI01012.1
CCDSiCCDS33121.1
RefSeqiNP_001307300.1, NM_001320371.1
NP_653291.1, NM_144690.2
UniGeneiHs.244391
Hs.655905

3D structure databases

ProteinModelPortaliQ96NG8
SMRiQ96NG8
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi127104, 1 interactor
STRINGi9606.ENSP00000301310

PTM databases

iPTMnetiQ96NG8
PhosphoSitePlusiQ96NG8

Polymorphism and mutation databases

BioMutaiZNF582
DMDMi74732564

Proteomic databases

PaxDbiQ96NG8
PeptideAtlasiQ96NG8
PRIDEiQ96NG8
ProteomicsDBi77511

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
147948
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000301310; ENSP00000301310; ENSG00000018869
ENST00000586929; ENSP00000465619; ENSG00000018869
ENST00000619584; ENSP00000483414; ENSG00000018869
GeneIDi147948
KEGGihsa:147948
UCSCiuc002qmz.1 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
147948
DisGeNETi147948
EuPathDBiHostDB:ENSG00000018869.16

GeneCards: human genes, protein and diseases

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GeneCardsi
ZNF582
HGNCiHGNC:26421 ZNF582
HPAiHPA028858
MIMi615600 gene
neXtProtiNX_Q96NG8
OpenTargetsiENSG00000018869
PharmGKBiPA134989661

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00940000162794
HOGENOMiHOG000234617
HOVERGENiHBG018163
InParanoidiQ96NG8
KOiK09228
OMAiRKDFWQE
OrthoDBiEOG091G02KC
PhylomeDBiQ96NG8
TreeFamiTF337055

Enzyme and pathway databases

ReactomeiR-HSA-212436 Generic Transcription Pathway

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
147948

Protein Ontology

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PROi
PR:Q96NG8

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000018869 Expressed in 141 organ(s), highest expression level in gastrocnemius
CleanExiHS_ZNF582
ExpressionAtlasiQ96NG8 baseline and differential
GenevisibleiQ96NG8 HS

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 9 hits
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 9 hits
SUPFAMiSSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 6 hits
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 9 hits
PS50157 ZINC_FINGER_C2H2_2, 10 hits

ProtoNet; Automatic hierarchical classification of proteins

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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN582_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96NG8
Secondary accession number(s): B4DQZ9, B7Z9R3, Q6PJT6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: December 1, 2001
Last modified: December 5, 2018
This is version 139 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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