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Entry version 146 (16 Oct 2019)
Sequence version 1 (01 Dec 2001)
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Protein

Zinc finger protein 558

Gene

ZNF558

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri152 – 174C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri180 – 202C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri208 – 230C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri236 – 258C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri264 – 286C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri292 – 314C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri320 – 342C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri348 – 370C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri376 – 398C2H2-type 9PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-212436 Generic Transcription Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 558
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF558
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:26422 ZNF558

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q96NG5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000167785

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134899314

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q96NG5

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF558

Domain mapping of disease mutations (DMDM)

More...
DMDMi
68566225

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000476481 – 402Zinc finger protein 558Add BLAST402

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q96NG5

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q96NG5

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q96NG5

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q96NG5

PeptideAtlas

More...
PeptideAtlasi
Q96NG5

PRoteomics IDEntifications database

More...
PRIDEi
Q96NG5

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
77510 [Q96NG5-1]

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
Q96NG5-1 [Q96NG5-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q96NG5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q96NG5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000167785 Expressed in 184 organ(s), highest expression level in amniotic fluid

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q96NG5 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA003151

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
127124, 10 interactors

Protein interaction database and analysis system

More...
IntActi
Q96NG5, 15 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000471277

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q96NG5

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini43 – 114KRABPROSITE-ProRule annotationAdd BLAST72

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri152 – 174C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri180 – 202C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri208 – 230C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri236 – 258C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri264 – 286C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri292 – 314C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri320 – 342C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri348 – 370C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri376 – 398C2H2-type 9PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721 Eukaryota
COG5048 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160844

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000234617

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q96NG5

KEGG Orthology (KO)

More...
KOi
K09228

Identification of Orthologs from Complete Genome Data

More...
OMAi
TRENHHE

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q96NG5

TreeFam database of animal gene trees

More...
TreeFami
TF337055

Family and domain databases

Conserved Domains Database

More...
CDDi
cd07765 KRAB_A-box, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 7 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 9 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 5 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 9 hits
PS50157 ZINC_FINGER_C2H2_2, 9 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q96NG5-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAAVILPSTA APSSLFPASQ QKGHTQGGEL VNELLTSWLR GLVTFEDVAV
60 70 80 90 100
EFTQEEWALL DPAQRTLYRD VMLENCRNLA SLGCRVNKPS LISQLEQDKK
110 120 130 140 150
VVTEERGILP STCPDLETLL KAKWLTPKKN VFRKEQSKGV KTERSHRGVK
160 170 180 190 200
LNECNQCFKV FSTKSNLTQH KRIHTGEKPY DCSQCGKSFS SRSYLTIHKR
210 220 230 240 250
IHNGEKPYEC NHCGKAFSDP SSLRLHLRIH TGEKPYECNQ CFHVFRTSCN
260 270 280 290 300
LKSHKRIHTG ENHHECNQCG KAFSTRSSLT GHNSIHTGEK PYECHDCGKT
310 320 330 340 350
FRKSSYLTQH VRTHTGEKPY ECNECGKSFS SSFSLTVHKR IHTGEKPYEC
360 370 380 390 400
SDCGKAFNNL SAVKKHLRTH TGEKPYECNH CGKSFTSNSY LSVHKRIHNR

WI
Length:402
Mass (Da):45,755
Last modified:December 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBB77228C89FBDD61
GO
Isoform 2 (identifier: Q96NG5-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-71: Missing.

Note: No experimental confirmation available.
Show »
Length:331
Mass (Da):37,971
Checksum:i3BE50C78C82A97E5
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0559631 – 71Missing in isoform 2. 1 PublicationAdd BLAST71

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK055494 mRNA Translation: BAB70934.1
AK291265 mRNA Translation: BAF83954.1
AK301664 mRNA Translation: BAH13534.1
AC008734 Genomic DNA No translation available.
AC012616 Genomic DNA No translation available.
CH471106 Genomic DNA Translation: EAW83994.1
BC064356 mRNA Translation: AAH64356.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS12208.1 [Q96NG5-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001291279.1, NM_001304350.1 [Q96NG5-2]
NP_653294.1, NM_144693.2 [Q96NG5-1]
XP_011526005.1, XM_011527703.2 [Q96NG5-2]
XP_016881859.1, XM_017026370.1 [Q96NG5-2]
XP_016881860.1, XM_017026371.1 [Q96NG5-2]
XP_016881861.1, XM_017026372.1 [Q96NG5-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000301475; ENSP00000301475; ENSG00000167785 [Q96NG5-1]
ENST00000601372; ENSP00000471277; ENSG00000167785 [Q96NG5-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
148156

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:148156

UCSC genome browser

More...
UCSCi
uc002mkn.1 human [Q96NG5-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK055494 mRNA Translation: BAB70934.1
AK291265 mRNA Translation: BAF83954.1
AK301664 mRNA Translation: BAH13534.1
AC008734 Genomic DNA No translation available.
AC012616 Genomic DNA No translation available.
CH471106 Genomic DNA Translation: EAW83994.1
BC064356 mRNA Translation: AAH64356.1
CCDSiCCDS12208.1 [Q96NG5-1]
RefSeqiNP_001291279.1, NM_001304350.1 [Q96NG5-2]
NP_653294.1, NM_144693.2 [Q96NG5-1]
XP_011526005.1, XM_011527703.2 [Q96NG5-2]
XP_016881859.1, XM_017026370.1 [Q96NG5-2]
XP_016881860.1, XM_017026371.1 [Q96NG5-2]
XP_016881861.1, XM_017026372.1 [Q96NG5-2]

3D structure databases

SMRiQ96NG5
ModBaseiSearch...

Protein-protein interaction databases

BioGridi127124, 10 interactors
IntActiQ96NG5, 15 interactors
STRINGi9606.ENSP00000471277

PTM databases

iPTMnetiQ96NG5
PhosphoSitePlusiQ96NG5

Polymorphism and mutation databases

BioMutaiZNF558
DMDMi68566225

Proteomic databases

EPDiQ96NG5
MassIVEiQ96NG5
MaxQBiQ96NG5
PaxDbiQ96NG5
PeptideAtlasiQ96NG5
PRIDEiQ96NG5
ProteomicsDBi77510 [Q96NG5-1]
TopDownProteomicsiQ96NG5-1 [Q96NG5-1]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
148156

Genome annotation databases

EnsembliENST00000301475; ENSP00000301475; ENSG00000167785 [Q96NG5-1]
ENST00000601372; ENSP00000471277; ENSG00000167785 [Q96NG5-1]
GeneIDi148156
KEGGihsa:148156
UCSCiuc002mkn.1 human [Q96NG5-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
148156

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZNF558
HGNCiHGNC:26422 ZNF558
HPAiHPA003151
neXtProtiNX_Q96NG5
OpenTargetsiENSG00000167785
PharmGKBiPA134899314

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00940000160844
HOGENOMiHOG000234617
InParanoidiQ96NG5
KOiK09228
OMAiTRENHHE
OrthoDBi1318335at2759
PhylomeDBiQ96NG5
TreeFamiTF337055

Enzyme and pathway databases

ReactomeiR-HSA-212436 Generic Transcription Pathway

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
ZNF558 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
148156
PharosiQ96NG5

Protein Ontology

More...
PROi
PR:Q96NG5

Gene expression databases

BgeeiENSG00000167785 Expressed in 184 organ(s), highest expression level in amniotic fluid
GenevisibleiQ96NG5 HS

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 7 hits
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 9 hits
SUPFAMiSSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 5 hits
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 9 hits
PS50157 ZINC_FINGER_C2H2_2, 9 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN558_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96NG5
Secondary accession number(s): A8K5F0, B7Z798
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: December 1, 2001
Last modified: October 16, 2019
This is version 146 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
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