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Entry version 143 (11 Dec 2019)
Sequence version 2 (03 Apr 2013)
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Protein

Zinc finger protein 578

Gene

ZNF578

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri231 – 253C2H2-type 1; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri259 – 281C2H2-type 2; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri287 – 309C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri315 – 337C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri343 – 365C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri371 – 393C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri399 – 421C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri427 – 449C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri455 – 477C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri483 – 505C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri511 – 533C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri539 – 561C2H2-type 12PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 578
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF578
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000258405.9

Human Gene Nomenclature Database

More...
HGNCi
HGNC:26449 ZNF578

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q96N58

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000258405

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134936072

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q96N58 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF578

Domain mapping of disease mutations (DMDM)

More...
DMDMi
476007824

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000476681 – 590Zinc finger protein 578Add BLAST590

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q96N58

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q96N58

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q96N58

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q96N58

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q96N58

PeptideAtlas

More...
PeptideAtlasi
Q96N58

PRoteomics IDEntifications database

More...
PRIDEi
Q96N58

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
46783
77467

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q96N58

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q96N58

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000258405 Expressed in 100 organ(s), highest expression level in heart

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q96N58 baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
127070, 6 interactors

Protein interaction database and analysis system

More...
IntActi
Q96N58, 11 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000459216

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q96N58 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q96N58

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini24 – 98KRABPROSITE-ProRule annotationAdd BLAST75

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri231 – 253C2H2-type 1; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri259 – 281C2H2-type 2; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri287 – 309C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri315 – 337C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri343 – 365C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri371 – 393C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri399 – 421C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri427 – 449C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri455 – 477C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri483 – 505C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri511 – 533C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri539 – 561C2H2-type 12PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721 Eukaryota
COG5048 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154397

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q96N58

Identification of Orthologs from Complete Genome Data

More...
OMAi
RHESYHT

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q96N58

TreeFam database of animal gene trees

More...
TreeFami
TF341892

Family and domain databases

Conserved Domains Database

More...
CDDi
cd07765 KRAB_A-box, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 6 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 12 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 7 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 10 hits
PS50157 ZINC_FINGER_C2H2_2, 12 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q96N58-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLHEEAAQKR KGKEPGMALP QGRLTFRDVA IEFSLAEWKF LNPAQRALYR
60 70 80 90 100
EVMLENYRNL EAVDISSKRM MKEVLSTGQG NTEVIHTGML QRHESYHTGD
110 120 130 140 150
FCFQEIEKDI HDFEFQSQKD ERNGHEASMP KIKELMGSTD RHDQRHAGNK
160 170 180 190 200
PIKDQLGLSF HLHLPELHIF QPEEKIANQV EKSVNDASSI STSQRISCRP
210 220 230 240 250
ETHTPNNYGN NFFHSSLLTQ KQEVHMREKS FQCNETGEAF NCSSFVRKHQ
260 270 280 290 300
IIHLGEKQYK FDICGKVFNE KRYLARHRRC HTSEKPYKCN ECGKSFSYKS
310 320 330 340 350
SLTCHRRCHT GEKPYKCNEC GKSFSYKSSL TCHHRCHTGE KPYKCNECGK
360 370 380 390 400
SFSYKSSLRC HRRLHTGIKP YKCNECGKMF GQNSTLVIHK AIHTGEKPYK
410 420 430 440 450
CNECGKAFNQ QSHLSRHHRL HTGEKPYKCN DCGKAFIHQS SLARHHRLHT
460 470 480 490 500
GEKSYKCEEC DRVFSQKSNL ERHKIIHTGE KPYKCNECHK TFSHRSSLPC
510 520 530 540 550
HRRLHSGEKP YKCNECGKTF NVQSHLSRHH RLHTGEKPYK CKVCDKAFMC
560 570 580 590
HSYLANHTRI HSGEKPYKCN ECGKAHNHLI DSSIKPCMSS
Length:590
Mass (Da):68,531
Last modified:April 3, 2013 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB2A987979C0574A9
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M0QZV4M0QZV4_HUMAN
Zinc finger protein 578
ZNF578
253Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAB71051 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_069167238E → K1 PublicationCorresponds to variant dbSNP:rs161931Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK055946 mRNA Translation: BAB71051.1 Different initiation.
AK299106 mRNA Translation: BAG61163.1
AC010332 Genomic DNA No translation available.
AC010506 Genomic DNA No translation available.
AC022150 Genomic DNA No translation available.
CH471135 Genomic DNA Translation: EAW72083.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS54310.1

NCBI Reference Sequences

More...
RefSeqi
NP_001093164.1, NM_001099694.1
XP_016881791.1, XM_017026302.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000421239; ENSP00000459216; ENSG00000258405

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
147660

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:147660

UCSC genome browser

More...
UCSCi
uc002pzp.5 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK055946 mRNA Translation: BAB71051.1 Different initiation.
AK299106 mRNA Translation: BAG61163.1
AC010332 Genomic DNA No translation available.
AC010506 Genomic DNA No translation available.
AC022150 Genomic DNA No translation available.
CH471135 Genomic DNA Translation: EAW72083.1
CCDSiCCDS54310.1
RefSeqiNP_001093164.1, NM_001099694.1
XP_016881791.1, XM_017026302.1

3D structure databases

SMRiQ96N58
ModBaseiSearch...

Protein-protein interaction databases

BioGridi127070, 6 interactors
IntActiQ96N58, 11 interactors
STRINGi9606.ENSP00000459216

PTM databases

iPTMnetiQ96N58
PhosphoSitePlusiQ96N58

Polymorphism and mutation databases

BioMutaiZNF578
DMDMi476007824

Proteomic databases

EPDiQ96N58
jPOSTiQ96N58
MassIVEiQ96N58
MaxQBiQ96N58
PaxDbiQ96N58
PeptideAtlasiQ96N58
PRIDEiQ96N58
ProteomicsDBi46783
77467

Genome annotation databases

EnsembliENST00000421239; ENSP00000459216; ENSG00000258405
GeneIDi147660
KEGGihsa:147660
UCSCiuc002pzp.5 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
147660
EuPathDBiHostDB:ENSG00000258405.9

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZNF578
HGNCiHGNC:26449 ZNF578
neXtProtiNX_Q96N58
OpenTargetsiENSG00000258405
PharmGKBiPA134936072

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00940000154397
InParanoidiQ96N58
OMAiRHESYHT
OrthoDBi1318335at2759
PhylomeDBiQ96N58
TreeFamiTF341892

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
ZNF578 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
147660
PharosiQ96N58 Tdark

Protein Ontology

More...
PROi
PR:Q96N58
RNActiQ96N58 protein

Gene expression databases

BgeeiENSG00000258405 Expressed in 100 organ(s), highest expression level in heart
ExpressionAtlasiQ96N58 baseline and differential

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 6 hits
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 12 hits
SUPFAMiSSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 7 hits
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 10 hits
PS50157 ZINC_FINGER_C2H2_2, 12 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN578_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96N58
Secondary accession number(s): B4DR51, I3L1Y6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 27, 2004
Last sequence update: April 3, 2013
Last modified: December 11, 2019
This is version 143 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
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