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UniProtKB - Q96N38 (ZN714_HUMAN)

Entry version 158 (23 Feb 2022)
Sequence version 3 (24 Jul 2013)
Previous versions | rss
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Protein

Zinc finger protein 714

Gene

ZNF714

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri116 – 138C2H2-type 1; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri144 – 166C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri172 – 194C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri200 – 222C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri228 – 250C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri256 – 278C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri284 – 306C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri312 – 334C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri340 – 362C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri368 – 390C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri396 – 418C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri424 – 446C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri452 – 474C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri480 – 502C2H2-type 14; degeneratePROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q96N38

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-212436, Generic Transcription Pathway

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		Q96N38

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 714
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF714
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:27124, ZNF714

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q96N38

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA143485680

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q96N38, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ZNF714

Domain mapping of disease mutations (DMDM)

More...DMDMi		527504073

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003317491 – 554Zinc finger protein 714Add BLAST554

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q96N38

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q96N38

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q96N38

PeptideAtlas

More...PeptideAtlasi		Q96N38

PRoteomics IDEntifications database

More...PRIDEi		Q96N38

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		77461 [Q96N38-1]
77462 [Q96N38-2]
77463 [Q96N38-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q96N38

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q96N38

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		127129, 12 interactors

Protein interaction database and analysis system

More...IntActi		Q96N38, 4 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000478345

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q96N38, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q96N38

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 47KRABPROSITE-ProRule annotationAdd BLAST47

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the krueppel C2H2-type zinc-finger protein family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri116 – 138C2H2-type 1; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri144 – 166C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri172 – 194C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri200 – 222C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri228 – 250C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri256 – 278C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri284 – 306C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri312 – 334C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri340 – 362C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri368 – 390C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri396 – 418C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri424 – 446C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri452 – 474C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri480 – 502C2H2-type 14; degeneratePROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1721, Eukaryota

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q96N38

Database of Orthologous Groups

More...OrthoDBi		1318335at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q96N38

TreeFam database of animal gene trees

More...TreeFami		TF342117

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR001909, KRAB
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00096, zf-C2H2, 12 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00349, KRAB, 1 hit
SM00355, ZnF_C2H2, 13 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF57667, SSF57667, 7 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50805, KRAB, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 12 hits
PS50157, ZINC_FINGER_C2H2_2, 14 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 7 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q96N38-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <p><strong>What is the canonical sequence?</strong><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MNVMLENYKN LVFLAGIAVS KQDPITSLEQ EKEPWNMKIC EMVDESPAMC 
        60         70         80         90        100
SSFTRDLWPE QDIKDSFQQV ILRRHGKCEH ENLQLRKGSA NVVECKVYKK 
       110        120        130        140        150
GYELNQCLTT TQSKIFPCDK YIKVFHKIFN SNRHKTRHTG EKPFKCKKCD 
       160        170        180        190        200
ESFCMLLHLH QHKRIHIREN SYQCEECDKV FKRFSTLTRH KRVHTGEKPF 
       210        220        230        240        250
KCEECGKAFK HSSTLTTHKM IHTGEKPYRC EECGKAFYHS SHLTTHKVIH 
       260        270        280        290        300
TGEKPFKCEE CGKAFNHPSA LTTHKFIHVK EKPYKCEECD KAFNRFSYLT 
       310        320        330        340        350
KHKIIHSGEK SYKCEQCGKG FNWSSTLTKH KRIHTGEKPY KCEECGKAFN 
       360        370        380        390        400
VSSHLTTHKM IHTGEKPYKC EECGKAFNHS SKLTIHKIIH TGEKPYKCEE 
       410        420        430        440        450
CGKAFNQSSN LTKHKIIHTG EKLYKCEECG KAFNRSSNLT THKRIHTGEK 
       460        470        480        490        500
PYKCEECGKA FNRSSNLTKH NIIHTGEKSY KCEECGKAFN QSSTLTKHRK 
       510        520        530        540        550
IQQGMVAHAC NPNTLRGLGE QIARSGVQDQ PGQHGKTPSL LKIQKFAGCG 

GRRL
Length:554
Mass (Da):63,883
Last modified:July 24, 2013 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i09150D7B5CF383C4
GO
Isoform 2 (identifier: Q96N38-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     516-523: RGLGEQIA → GGQGRWIT
     524-554: Missing.

Show »
Length:523
Mass (Da):60,612
Checksum:i2ED3B283FDBB3673
GO
Isoform 3 (identifier: Q96N38-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-154: Missing.

Show »
Length:400
Mass (Da):45,842
Checksum:i9AE799291B2195EB
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A087WU35A0A087WU35_HUMAN
Zinc finger protein 714
ZNF714
555Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087X1Z8A0A087X1Z8_HUMAN
Zinc finger protein 714
ZNF714
139Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0QY60M0QY60_HUMAN
Zinc finger protein 714
ZNF714
110Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WX89A0A087WX89_HUMAN
Zinc finger protein 714
ZNF714
55Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
I3L2D0I3L2D0_HUMAN
Zinc finger protein 714
ZNF714
84Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WV13A0A087WV13_HUMAN
Zinc finger protein 714
ZNF714
28Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087X1X4A0A087X1X4_HUMAN
Zinc finger protein 714
ZNF714
148Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH50468 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
The sequence CAD39077 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti102Y → YN in BAB71072 (PubMed:14702039).Curated1
Sequence conflicti102Y → YN in CAD39077 (PubMed:17974005).Curated1
Sequence conflicti102Y → YN in AAH50468 (PubMed:15489334).Curated1
Sequence conflicti513N → S in CAD39077 (PubMed:17974005).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_042936331K → R3 PublicationsCorresponds to variant dbSNP:rs2884554Ensembl.1
Natural variantiVAR_057448472I → V. Corresponds to variant dbSNP:rs10427116Ensembl.1
Natural variantiVAR_042937473I → V. Corresponds to variant dbSNP:rs10427116Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0333191 – 154Missing in isoform 3. 1 PublicationAdd BLAST154
Alternative sequenceiVSP_033320516 – 523RGLGEQIA → GGQGRWIT in isoform 2. 1 Publication8
Alternative sequenceiVSP_033321524 – 554Missing in isoform 2. 1 PublicationAdd BLAST31

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK056006 mRNA Translation: BAB71072.1
AL834415 mRNA Translation: CAD39077.1 Different initiation.
AC010620 Genomic DNA No translation available.
AC012627 Genomic DNA No translation available.
BC037782 mRNA Translation: AAH37782.1
BC050468 mRNA Translation: AAH50468.2 Different initiation.

NCBI Reference Sequences

More...RefSeqi		NP_872321.2, NM_182515.3

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...GeneIDi		148206

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:148206

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK056006 mRNA Translation: BAB71072.1
AL834415 mRNA Translation: CAD39077.1 Different initiation.
AC010620 Genomic DNA No translation available.
AC012627 Genomic DNA No translation available.
BC037782 mRNA Translation: AAH37782.1
BC050468 mRNA Translation: AAH50468.2 Different initiation.
RefSeqiNP_872321.2, NM_182515.3

3D structure databases

SMRiQ96N38
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi127129, 12 interactors
IntActiQ96N38, 4 interactors
STRINGi9606.ENSP00000478345

PTM databases

iPTMnetiQ96N38
PhosphoSitePlusiQ96N38

Genetic variation databases

BioMutaiZNF714
DMDMi527504073

Proteomic databases

jPOSTiQ96N38
MassIVEiQ96N38
PaxDbiQ96N38
PeptideAtlasiQ96N38
PRIDEiQ96N38
ProteomicsDBi77461 [Q96N38-1]
77462 [Q96N38-2]
77463 [Q96N38-3]

Protocols and materials databases

The DNASU plasmid repository

More...DNASUi		148206

Genome annotation databases

GeneIDi148206
KEGGihsa:148206

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		148206

GeneCards: human genes, protein and diseases

More...GeneCardsi		ZNF714
HGNCiHGNC:27124, ZNF714
neXtProtiNX_Q96N38
PharmGKBiPA143485680

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
InParanoidiQ96N38
OrthoDBi1318335at2759
PhylomeDBiQ96N38
TreeFamiTF342117

Enzyme and pathway databases

PathwayCommonsiQ96N38
ReactomeiR-HSA-212436, Generic Transcription Pathway
SignaLinkiQ96N38

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		148206, 14 hits in 996 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		ZNF714, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		148206
PharosiQ96N38, Tdark

Protein Ontology

More...PROi		PR:Q96N38
RNActiQ96N38, protein

Family and domain databases

InterProiView protein in InterPro
IPR001909, KRAB
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF00096, zf-C2H2, 12 hits
SMARTiView protein in SMART
SM00349, KRAB, 1 hit
SM00355, ZnF_C2H2, 13 hits
SUPFAMiSSF57667, SSF57667, 7 hits
PROSITEiView protein in PROSITE
PS50805, KRAB, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 12 hits
PS50157, ZINC_FINGER_C2H2_2, 14 hits

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN714_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96N38
Secondary accession number(s): Q49AI1, Q86W65, Q8ND40
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: July 24, 2013
Last modified: February 23, 2022
This is version 158 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. SIMILARITY comments
    Index of protein domains and families
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