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Entry version 155 (02 Jun 2021)
Sequence version 2 (18 May 2010)
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Protein

Zinc finger protein 48

Gene

ZNF48

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri112 – 134C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri140 – 162C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri192 – 214C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri220 – 242C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri275 – 297C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri303 – 325C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri331 – 353C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri359 – 381C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri451 – 473C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri479 – 501C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri543 – 565C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri571 – 593C2H2-type 12PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q96MX3

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 48
Alternative name(s):
Zinc finger protein 553
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF48
Synonyms:ZNF553
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 16

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:13114, ZNF48

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q96MX3

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000180035.10

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000180035

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA37689

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q96MX3, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF48

Domain mapping of disease mutations (DMDM)

More...
DMDMi
296453060

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002345861 – 618Zinc finger protein 48Add BLAST618

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki87Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki179Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki269Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki329Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki477Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki610Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources

Keywords - PTMi

Acetylation, Isopeptide bond, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q96MX3

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
Q96MX3

MassIVE - Mass Spectrometry Interactive Virtual Environment

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MassIVEi
Q96MX3

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q96MX3

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q96MX3

PeptideAtlas

More...
PeptideAtlasi
Q96MX3

PRoteomics IDEntifications database

More...
PRIDEi
Q96MX3

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
77428

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
Q96MX3

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q96MX3

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q96MX3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000180035, Expressed in muscle tissue and 199 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q96MX3, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q96MX3, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000180035, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
128257, 34 interactors

Protein interaction database and analysis system

More...
IntActi
Q96MX3, 26 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000480262

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q96MX3, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q96MX3

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 51DisorderedSequence analysisAdd BLAST51
Regioni78 – 109DisorderedSequence analysisAdd BLAST32
Regioni157 – 189DisorderedSequence analysisAdd BLAST33
Regioni235 – 271DisorderedSequence analysisAdd BLAST37
Regioni392 – 457DisorderedSequence analysisAdd BLAST66
Regioni500 – 540DisorderedSequence analysisAdd BLAST41

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 24Basic and acidic residuesSequence analysisAdd BLAST24
Compositional biasi235 – 249Basic and acidic residuesSequence analysisAdd BLAST15
Compositional biasi394 – 412Pro residuesSequence analysisAdd BLAST19
Compositional biasi434 – 449Pro residuesSequence analysisAdd BLAST16
Compositional biasi510 – 532Pro residuesSequence analysisAdd BLAST23

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri112 – 134C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri140 – 162C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri192 – 214C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri220 – 242C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri275 – 297C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri303 – 325C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri331 – 353C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri359 – 381C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri451 – 473C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri479 – 501C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri543 – 565C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri571 – 593C2H2-type 12PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000162332

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q96MX3

Identification of Orthologs from Complete Genome Data

More...
OMAi
QTWDDLW

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q96MX3

TreeFam database of animal gene trees

More...
TreeFami
TF338489

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00096, zf-C2H2, 12 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00355, ZnF_C2H2, 12 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57667, SSF57667, 6 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 12 hits
PS50157, ZINC_FINGER_C2H2_2, 12 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q96MX3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MERAVEPWGP DLHRPEEREP QRGARTGLGS ENVISQPNEF EHTPQEDDLG
60 70 80 90 100
FKEEDLAPDH EVGNASLKPE GIQNWDDLWV QREGLGKPQP RDRGPRLLGE
110 120 130 140 150
PRWGQASSDR AAVCGECGKS FRQMSDLVKH QRTHTGEKPY KCGVCGKGFG
160 170 180 190 200
DSSARIKHQR THSGEKPYRA RPPAQGPPKI PRSRIPAGER PTICGECGKS
210 220 230 240 250
FRQSSDLVKH QRTHTGEKPY KCGICGKGFG DSSARIKHQR THRGEQPPRP
260 270 280 290 300
VVPRRQPSRA ATAATQGPKA QDKPYICTDC GKRFVLSCSL LSHQRSHLGP
310 320 330 340 350
KPFGCDVCGK EFARGSDLVK HLRVHTGEKP YLCPECGKGF ADSSARVKHL
360 370 380 390 400
RTHSGERPHA CPECDRTFSL SSTLLRHRLT HMEPQDFSFP GYPLPALIPS
410 420 430 440 450
PPPPPLGTSP PLTPRSPSHS GEPFGLPGLE PEPGGPQAGE PPPPLAGDKP
460 470 480 490 500
HKCPECGKGF RRSSDLVKHH RVHTGEKPYL CPECGKGFAD SSARVKHLRT
510 520 530 540 550
HRGERARPPP PSTLLRPHNP PGPVPMAPRP RVRAQPSGPS QPHVCGFCGK
560 570 580 590 600
EFPRSSDLVK HRRTHTGEKP YKCAECGKGF GDSSARIKHQ RGHLVLTPFG
610
IGDGRARPLK QEAATGLE
Length:618
Mass (Da):67,820
Last modified:May 18, 2010 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB31CB196816B2D93
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A087WVT1A0A087WVT1_HUMAN
Zinc finger protein 48
ZNF48
495Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PJ50E9PJ50_HUMAN
Zinc finger protein 48
ZNF48
147Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAA61316 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti12L → I in AAH41388 (PubMed:15616553).Curated1
Sequence conflicti140Y → C in AAH41388 (PubMed:15616553).Curated1
Sequence conflicti203Q → L in BAB71146 (PubMed:14702039).Curated1
Sequence conflicti344S → P in AAH41388 (PubMed:15616553).Curated1
Sequence conflicti351R → H in AAH41388 (PubMed:15616553).Curated1
Sequence conflicti451H → R in AAH41388 (PubMed:15616553).Curated1
Sequence conflicti563R → H in AAH41388 (PubMed:15616553).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_05989421Q → R. Corresponds to variant dbSNP:rs7200143Ensembl.1
Natural variantiVAR_05275865A → V3 PublicationsCorresponds to variant dbSNP:rs12921440Ensembl.1
Natural variantiVAR_052759224I → V. Corresponds to variant dbSNP:rs34843513Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK056313 mRNA Translation: BAB71146.1
AC116348 Genomic DNA No translation available.
BC007393 mRNA Translation: AAH07393.2
BC041388 mRNA Translation: AAH41388.1
M88358 Genomic DNA Translation: AAA61316.1 Frameshift.
AL832433 mRNA Translation: CAH10657.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS10679.1

Protein sequence database of the Protein Information Resource

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PIRi
B43284

NCBI Reference Sequences

More...
RefSeqi
NP_001201835.1, NM_001214906.1
NP_001201838.1, NM_001214909.1
NP_689865.2, NM_152652.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000320159; ENSP00000324056; ENSG00000180035
ENST00000613509; ENSP00000480262; ENSG00000180035

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
197407

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:197407

UCSC genome browser

More...
UCSCi
uc002dya.2, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK056313 mRNA Translation: BAB71146.1
AC116348 Genomic DNA No translation available.
BC007393 mRNA Translation: AAH07393.2
BC041388 mRNA Translation: AAH41388.1
M88358 Genomic DNA Translation: AAA61316.1 Frameshift.
AL832433 mRNA Translation: CAH10657.1
CCDSiCCDS10679.1
PIRiB43284
RefSeqiNP_001201835.1, NM_001214906.1
NP_001201838.1, NM_001214909.1
NP_689865.2, NM_152652.2

3D structure databases

SMRiQ96MX3
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi128257, 34 interactors
IntActiQ96MX3, 26 interactors
STRINGi9606.ENSP00000480262

PTM databases

iPTMnetiQ96MX3
PhosphoSitePlusiQ96MX3

Genetic variation databases

BioMutaiZNF48
DMDMi296453060

Proteomic databases

EPDiQ96MX3
jPOSTiQ96MX3
MassIVEiQ96MX3
MaxQBiQ96MX3
PaxDbiQ96MX3
PeptideAtlasiQ96MX3
PRIDEiQ96MX3
ProteomicsDBi77428
TopDownProteomicsiQ96MX3

Protocols and materials databases

Antibodypedia a portal for validated antibodies

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Antibodypediai
13692, 30 antibodies

The DNASU plasmid repository

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DNASUi
197407

Genome annotation databases

EnsembliENST00000320159; ENSP00000324056; ENSG00000180035
ENST00000613509; ENSP00000480262; ENSG00000180035
GeneIDi197407
KEGGihsa:197407
UCSCiuc002dya.2, human

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
197407

GeneCards: human genes, protein and diseases

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GeneCardsi
ZNF48
HGNCiHGNC:13114, ZNF48
HPAiENSG00000180035, Low tissue specificity
neXtProtiNX_Q96MX3
OpenTargetsiENSG00000180035
PharmGKBiPA37689
VEuPathDBiHostDB:ENSG00000180035.10

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG1721, Eukaryota
GeneTreeiENSGT00940000162332
InParanoidiQ96MX3
OMAiQTWDDLW
OrthoDBi1318335at2759
PhylomeDBiQ96MX3
TreeFamiTF338489

Enzyme and pathway databases

PathwayCommonsiQ96MX3

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
197407, 12 hits in 1016 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
ZNF48, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
197407
PharosiQ96MX3, Tdark

Protein Ontology

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PROi
PR:Q96MX3
RNActiQ96MX3, protein

Gene expression databases

BgeeiENSG00000180035, Expressed in muscle tissue and 199 other tissues
ExpressionAtlasiQ96MX3, baseline and differential
GenevisibleiQ96MX3, HS

Family and domain databases

InterProiView protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF00096, zf-C2H2, 12 hits
SMARTiView protein in SMART
SM00355, ZnF_C2H2, 12 hits
SUPFAMiSSF57667, SSF57667, 6 hits
PROSITEiView protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 12 hits
PS50157, ZINC_FINGER_C2H2_2, 12 hits

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZNF48_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96MX3
Secondary accession number(s): Q15920
, Q4G0R3, Q69YP3, Q96IL9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: May 18, 2010
Last modified: June 2, 2021
This is version 155 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. SIMILARITY comments
    Index of protein domains and families
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