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Protein

Uncharacterized protein C17orf77

Gene

C17orf77

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C17orf77
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

HGNCiHGNC:26480 C17orf77
neXtProtiNX_Q96MU5

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Polymorphism and mutation databases

BioMutaiC17orf77
DMDMi313104095

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_000026423920 – 243Uncharacterized protein C17orf77Add BLAST224

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi136N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ96MU5
PRIDEiQ96MU5
ProteomicsDBi77410

PTM databases

iPTMnetiQ96MU5
PhosphoSitePlusiQ96MU5

Expressioni

Gene expression databases

CleanExiHS_C17orf77

Interactioni

Protein-protein interaction databases

IntActiQ96MU5, 5 interactors

Structurei

3D structure databases

ProteinModelPortaliQ96MU5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi111 – 132Cys-richAdd BLAST22

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410JMEY Eukaryota
ENOG41113JX LUCA
HOGENOMiHOG000170914
InParanoidiQ96MU5
PhylomeDBiQ96MU5
TreeFamiTF342090

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q96MU5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDELALSFSL TCLLPENRAS LSPSQPLSFQ CLKAPATLTW EDEKQQRWGQ
60 70 80 90 100
PHGPVSSPLL GDHRCLVPFR DLNPSSEVNT ANLLESPSSL LLTSCYICSY
110 120 130 140 150
FSFYILGEKR CHSLKRLRYS VCCKVCPNFC ACGKENVSGT GQVCTGVHVG
160 170 180 190 200
AKEQEEPGGT QALRSCGIYC LEERTDKASH EECRERSTLG RPQCTGLTPS
210 220 230 240
LAGESPCPRL LPGSPTVRHL IASSCPGLSD PLPLPPGTLP LGS
Length:243
Mass (Da):26,264
Last modified:November 30, 2010 - v2
Checksum:i43BBBF3D55CDF05A
GO

Sequence cautioni

The sequence AK056444 differs from that shown. Reason: Erroneous termination at position 207. Translated as Cys.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti57S → T in AK056444 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_02962847R → S1 PublicationCorresponds to variant dbSNP:rs493430Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK056444 mRNA No translation available.
AC079325 Genomic DNA No translation available.
RefSeqiNP_001289738.1, NM_001302809.1
NP_689673.2, NM_152460.2
UniGeneiHs.350775

Genome annotation databases

GeneIDi146723
KEGGihsa:146723

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK056444 mRNA No translation available.
AC079325 Genomic DNA No translation available.
RefSeqiNP_001289738.1, NM_001302809.1
NP_689673.2, NM_152460.2
UniGeneiHs.350775

3D structure databases

ProteinModelPortaliQ96MU5
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ96MU5, 5 interactors

PTM databases

iPTMnetiQ96MU5
PhosphoSitePlusiQ96MU5

Polymorphism and mutation databases

BioMutaiC17orf77
DMDMi313104095

Proteomic databases

PaxDbiQ96MU5
PRIDEiQ96MU5
ProteomicsDBi77410

Protocols and materials databases

DNASUi146723
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi146723
KEGGihsa:146723

Organism-specific databases

CTDi146723
GeneCardsiC17orf77
HGNCiHGNC:26480 C17orf77
neXtProtiNX_Q96MU5
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410JMEY Eukaryota
ENOG41113JX LUCA
HOGENOMiHOG000170914
InParanoidiQ96MU5
PhylomeDBiQ96MU5
TreeFamiTF342090

Miscellaneous databases

GenomeRNAii146723
PROiPR:Q96MU5

Gene expression databases

CleanExiHS_C17orf77

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiCQ077_HUMAN
AccessioniPrimary (citable) accession number: Q96MU5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: November 30, 2010
Last modified: June 20, 2018
This is version 93 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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Main funding by: National Institutes of Health

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