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Entry version 83 (07 Oct 2020)
Sequence version 1 (01 Dec 2001)
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Protein
Submitted name:

cDNA FLJ32105 fis, clone OCBBF2001402, moderately similar to Mus musculus NSD1 protein mRNA

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
cDNA FLJ32105 fis, clone OCBBF2001402, moderately similar to Mus musculus NSD1 protein mRNAImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA31790

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PeptideAtlas

More...
PeptideAtlasi
Q96MN8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q96MN8, HS

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni135 – 162DisorderedSequence analysisAdd BLAST28
Regioni520 – 539DisorderedSequence analysisAdd BLAST20
Regioni584 – 683DisorderedSequence analysisAdd BLAST100
Regioni715 – 741DisorderedSequence analysisAdd BLAST27
Regioni760 – 782DisorderedSequence analysisAdd BLAST23
Regioni891 – 918DisorderedSequence analysisAdd BLAST28

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi522 – 539PolarSequence analysisAdd BLAST18
Compositional biasi584 – 636PolarSequence analysisAdd BLAST53
Compositional biasi724 – 738PolyampholyteSequence analysisAdd BLAST15

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

Q96MN8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKVSNRRPYR QYYVEAFGDP SERAWVAGKA IVMFEGRHQF EELPVLRRRG
60 70 80 90 100
KQKEKGYRHK VPQKILSKWE ASVGLAEQYD VPKGSKNRKC IPGSIKLDSE
110 120 130 140 150
EDMPFEDCTN DPESEHDLLL NGCLKSLAFD SEHSADEKEK PCAKSRARKS
160 170 180 190 200
SDNPKRTSVK KGHIQFEAHK DERRGKIPEN LGLNFISGDI SDTQASNELS
210 220 230 240 250
RIANSLTGSN TAPGSFLFSS CGKNTAKKEF ETSNGDSLLG LPEGALISKC
260 270 280 290 300
SREKNKPQRS LVCGSKVKLC YIGAGDEEKR SDSISICTTS DDGSSDLDPI
310 320 330 340 350
EHSSESDNSV LEIPDAFDRT ENMLSMQKNE KIKYSRFAAT NTRVKAKQKP
360 370 380 390 400
LISNSHTDHL MGCTKSAEPG TETSQVNLSD LKASTLVHKP QSDFTNDALS
410 420 430 440 450
PKFNLSSSIS SENSLIKGGA ANQALLHSKS KQPKFRSIKC KHKENPVMAE
460 470 480 490 500
PPVINEECSL KCCSSDTKGS PLASISKSGK VDGLKLLNNM HEKTRDSSDI
510 520 530 540 550
ETAVVKHVLS ELKELSYRSL GEDVSDSGTS KPSKPLLFSS ASSQNHIPIE
560 570 580 590 600
PDYKFSTLLM MLKDMHDSKT KEQRLMTAQN LVSYRSPGRG DCSTNSPVGV
610 620 630 640 650
SKVLVSGGST HNSEKKGDGT QNSANPSPSG GDSALSGELS ASLPGLLSDK
660 670 680 690 700
RDLPASGKSR SDCVTRRNCG RSKPSSKLRD AFSAQMVKNT VNRKALKTER
710 720 730 740 750
KRKLNQLPSV TLDAVLQGDR ERGGSLRGGA EDPSKEDPLQ IMGHLTSEDG
760 770 780 790 800
DHFSDVHFDS KVKQSDPGKI SEKGLSFENG KGPELDSVMN SENDELNGVN
810 820 830 840 850
QVVPKKRWQR LNQRRTKPRK RMNRFKEKEN SECAFRVLLP SDPVQEGRDE
860 870 880 890 900
FPEHRTPSAS ILEEPLTEQN HADCLDSAGP RLNVCDKSSA SIGDMEKEPG
910 920 930 940
IPSLTPQAEL PEPAVRSEKK RLRKPSKWLL EYTEEYDQIF AP
Length:942
Mass (Da):103,771
Last modified:December 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i43C0991BD30CC527
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei942Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK056667 mRNA Translation: BAB71247.1

NCBI Reference Sequences

More...
RefSeqi
NP_758859.1, NM_172349.2

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
64324

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK056667 mRNA Translation: BAB71247.1
RefSeqiNP_758859.1, NM_172349.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

PeptideAtlasiQ96MN8

Genome annotation databases

GeneIDi64324

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
64324
PharmGKBiPA31790

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
64324, 75 hits in 879 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
64324

Gene expression databases

GenevisibleiQ96MN8, HS

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ96MN8_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96MN8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: October 7, 2020
This is version 83 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
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