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UniProtKB - Q96MH6 (TMM68_HUMAN)

Entry version 130 (07 Apr 2021)
Sequence version 2 (31 Oct 2006)
Previous versions | rss
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Protein

Transmembrane protein 68

Gene

TMEM68

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q96MH6

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transmembrane protein 68
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TMEM68
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:26510, TMEM68

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q96MH6

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000167904.14

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei51 – 71HelicalSequence analysisAdd BLAST21
Transmembranei126 – 146HelicalSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000167904

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA142670781

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q96MH6, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		TMEM68

Domain mapping of disease mutations (DMDM)

More...DMDMi		118574371

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002545921 – 324Transmembrane protein 68Add BLAST324

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q96MH6

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q96MH6

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q96MH6

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q96MH6

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q96MH6

PeptideAtlas

More...PeptideAtlasi		Q96MH6

PRoteomics IDEntifications database

More...PRIDEi		Q96MH6

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		77357 [Q96MH6-1]
77358 [Q96MH6-2]
77359 [Q96MH6-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q96MH6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q96MH6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000167904, Expressed in kidney and 202 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q96MH6, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q96MH6, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000167904, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		126482, 16 interactors

Protein interaction database and analysis system

More...IntActi		Q96MH6, 9 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000395204

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q96MH6, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q96MH6

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG4321, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000011782

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_056812_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q96MH6

Identification of Orthologs from Complete Genome Data

More...OMAi		FRWLYER

Database of Orthologous Groups

More...OrthoDBi		1558547at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q96MH6

TreeFam database of animal gene trees

More...TreeFami		TF312828

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR002123, Plipid/glycerol_acylTrfase

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01553, Acyltransferase, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 11 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q96MH6-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MIDKNQTCGV GQDSVPYMIC LIHILEEWFG VEQLEDYLNF ANYLLWVFTP 
        60         70         80         90        100
LILLILPYFT IFLLYLTIIF LHIYKRKNVL KEAYSHNLWD GARKTVATLW 
       110        120        130        140        150
DGHAAVWHGY EVHGMEKIPE DGPALIIFYH GAIPIDFYYF MAKIFIHKGR 
       160        170        180        190        200
TCRVVADHFV FKIPGFSLLL DVFCALHGPR EKCVEILRSG HLLAISPGGV 
       210        220        230        240        250
REALISDETY NIVWGHRRGF AQVAIDAKVP IIPMFTQNIR EGFRSLGGTR 
       260        270        280        290        300
LFRWLYEKFR YPFAPMYGGF PVKLRTYLGD PIPYDPQITA EELAEKTKNA 
       310        320 
VQALIDKHQR IPGNIMSALL ERFH
Length:324
Mass (Da):37,425
Last modified:October 31, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8A251314E727CE2E
GO
Isoform 2 (identifier: Q96MH6-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     230-296: Missing.

Show »
Length:257
Mass (Da):29,542
Checksum:i509DEC16B6FDA0CC
GO
Isoform 3 (identifier: Q96MH6-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     110-135: YEVHGMEKIPEDGPALIIFYHGAIPI → KQGYFHLCVAIHVCCIGTVLPFHFID
     136-324: Missing.

Show »
Length:135
Mass (Da):15,792
Checksum:i042A710F29235341
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 11 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E5RJN2E5RJN2_HUMAN
Transmembrane protein 68
TMEM68
144Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RHU1E5RHU1_HUMAN
Transmembrane protein 68
TMEM68
182Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YC64H0YC64_HUMAN
Transmembrane protein 68
TMEM68
134Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RGT2E5RGT2_HUMAN
Transmembrane protein 68
TMEM68
143Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RJI9E5RJI9_HUMAN
Transmembrane protein 68
TMEM68
243Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RHZ2E5RHZ2_HUMAN
Transmembrane protein 68
TMEM68
144Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RJ96E5RJ96_HUMAN
Transmembrane protein 68
TMEM68
164Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RHI6E5RHI6_HUMAN
Transmembrane protein 68
TMEM68
126Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q49A68Q49A68_HUMAN
TMEM68 protein
TMEM68
91Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YAX4H0YAX4_HUMAN
Transmembrane protein 68
TMEM68
108Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There is more potential isoformShow all

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_021244110 – 135YEVHG…GAIPI → KQGYFHLCVAIHVCCIGTVL PFHFID in isoform 3. 1 PublicationAdd BLAST26
Alternative sequenceiVSP_021245136 – 324Missing in isoform 3. 1 PublicationAdd BLAST189
Alternative sequenceiVSP_021246230 – 296Missing in isoform 2. 1 PublicationAdd BLAST67

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK056932 mRNA Translation: BAB71312.1
BC020835 mRNA Translation: AAH20835.1
BC071636 mRNA Translation: AAH71636.1
AL832935 mRNA Translation: CAH56335.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS6161.1 [Q96MH6-2]
CCDS75741.1 [Q96MH6-3]
CCDS75742.1 [Q96MH6-1]

NCBI Reference Sequences

More...RefSeqi		NP_001273586.1, NM_001286657.1 [Q96MH6-1]
NP_001273589.1, NM_001286660.1 [Q96MH6-3]
NP_689630.1, NM_152417.2 [Q96MH6-2]
XP_005251207.1, XM_005251150.1
XP_011515756.1, XM_011517454.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000334667; ENSP00000335416; ENSG00000167904 [Q96MH6-2]
ENST00000434581; ENSP00000395204; ENSG00000167904 [Q96MH6-1]
ENST00000521229; ENSP00000429210; ENSG00000167904 [Q96MH6-3]
ENST00000522576; ENSP00000431047; ENSG00000167904 [Q96MH6-3]
ENST00000617782; ENSP00000478242; ENSG00000167904 [Q96MH6-1]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		137695

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:137695

UCSC genome browser

More...UCSCi		uc003xsg.2, human [Q96MH6-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK056932 mRNA Translation: BAB71312.1
BC020835 mRNA Translation: AAH20835.1
BC071636 mRNA Translation: AAH71636.1
AL832935 mRNA Translation: CAH56335.1
CCDSiCCDS6161.1 [Q96MH6-2]
CCDS75741.1 [Q96MH6-3]
CCDS75742.1 [Q96MH6-1]
RefSeqiNP_001273586.1, NM_001286657.1 [Q96MH6-1]
NP_001273589.1, NM_001286660.1 [Q96MH6-3]
NP_689630.1, NM_152417.2 [Q96MH6-2]
XP_005251207.1, XM_005251150.1
XP_011515756.1, XM_011517454.1

3D structure databases

SMRiQ96MH6
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi126482, 16 interactors
IntActiQ96MH6, 9 interactors
STRINGi9606.ENSP00000395204

PTM databases

iPTMnetiQ96MH6
PhosphoSitePlusiQ96MH6

Genetic variation databases

BioMutaiTMEM68
DMDMi118574371

Proteomic databases

EPDiQ96MH6
jPOSTiQ96MH6
MassIVEiQ96MH6
MaxQBiQ96MH6
PaxDbiQ96MH6
PeptideAtlasiQ96MH6
PRIDEiQ96MH6
ProteomicsDBi77357 [Q96MH6-1]
77358 [Q96MH6-2]
77359 [Q96MH6-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		11708, 55 antibodies

Genome annotation databases

EnsembliENST00000334667; ENSP00000335416; ENSG00000167904 [Q96MH6-2]
ENST00000434581; ENSP00000395204; ENSG00000167904 [Q96MH6-1]
ENST00000521229; ENSP00000429210; ENSG00000167904 [Q96MH6-3]
ENST00000522576; ENSP00000431047; ENSG00000167904 [Q96MH6-3]
ENST00000617782; ENSP00000478242; ENSG00000167904 [Q96MH6-1]
GeneIDi137695
KEGGihsa:137695
UCSCiuc003xsg.2, human [Q96MH6-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		137695

GeneCards: human genes, protein and diseases

More...GeneCardsi		TMEM68
HGNCiHGNC:26510, TMEM68
HPAiENSG00000167904, Low tissue specificity
neXtProtiNX_Q96MH6
OpenTargetsiENSG00000167904
PharmGKBiPA142670781
VEuPathDBiHostDB:ENSG00000167904.14

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG4321, Eukaryota
GeneTreeiENSGT00390000011782
HOGENOMiCLU_056812_1_0_1
InParanoidiQ96MH6
OMAiFRWLYER
OrthoDBi1558547at2759
PhylomeDBiQ96MH6
TreeFamiTF312828

Enzyme and pathway databases

PathwayCommonsiQ96MH6

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		137695, 13 hits in 999 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		TMEM68, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		137695
PharosiQ96MH6, Tdark

Protein Ontology

More...PROi		PR:Q96MH6
RNActiQ96MH6, protein

Gene expression databases

BgeeiENSG00000167904, Expressed in kidney and 202 other tissues
ExpressionAtlasiQ96MH6, baseline and differential
GenevisibleiQ96MH6, HS

Family and domain databases

InterProiView protein in InterPro
IPR002123, Plipid/glycerol_acylTrfase
PfamiView protein in Pfam
PF01553, Acyltransferase, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTMM68_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96MH6
Secondary accession number(s): Q658X6, Q8WUD2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: October 31, 2006
Last modified: April 7, 2021
This is version 130 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
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