Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 154 (07 Oct 2020)
Sequence version 2 (05 May 2009)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Zinc finger protein 512

Gene

ZNF512

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri197 – 220C2H2-type 1PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri287 – 310C2H2-type 2PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri406 – 430C2H2-type 3; atypicalPROSITE-ProRule annotationAdd BLAST25
Zinc fingeri440 – 463C2H2-type 4PROSITE-ProRule annotationAdd BLAST24

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q96ME7

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 512
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF512
Synonyms:KIAA1805
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000243943.9

Human Gene Nomenclature Database

More...
HGNCi
HGNC:29380, ZNF512

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q96ME7

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
84450

Open Targets

More...
OpenTargetsi
ENSG00000243943

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134896861

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q96ME7, Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF512

Domain mapping of disease mutations (DMDM)

More...
DMDMi
229462786

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000476301 – 567Zinc finger protein 512Add BLAST567

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki18Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki84Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki227Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki333Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources

Keywords - PTMi

Isopeptide bond, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q96ME7

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q96ME7

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q96ME7

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q96ME7

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q96ME7

PeptideAtlas

More...
PeptideAtlasi
Q96ME7

PRoteomics IDEntifications database

More...
PRIDEi
Q96ME7

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
5037
70294
77343 [Q96ME7-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q96ME7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q96ME7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000243943, Expressed in female gonad and 205 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q96ME7, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q96ME7, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000243943, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
124088, 128 interactors

Protein interaction database and analysis system

More...
IntActi
Q96ME7, 90 interactors

Molecular INTeraction database

More...
MINTi
Q96ME7

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000347648

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q96ME7, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1567
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q96ME7

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
Q96ME7

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri197 – 220C2H2-type 1PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri287 – 310C2H2-type 2PROSITE-ProRule annotationAdd BLAST24
Zinc fingeri406 – 430C2H2-type 3; atypicalPROSITE-ProRule annotationAdd BLAST25
Zinc fingeri440 – 463C2H2-type 4PROSITE-ProRule annotationAdd BLAST24

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000158595

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_481412_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q96ME7

Identification of Orthologs from Complete Genome Data

More...
OMAi
DQRRSNE

Database of Orthologous Groups

More...
OrthoDBi
222563at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q96ME7

TreeFam database of animal gene trees

More...
TreeFami
TF331185

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00096, zf-C2H2, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00355, ZnF_C2H2, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57667, SSF57667, 5 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 3 hits
PS50157, ZINC_FINGER_C2H2_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q96ME7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSSRLGAVPA TSGPTTFKQQ RSTRIVGAKN SRTQCSIKDN SFQYTIPHDD
60 70 80 90 100
SLSGSSSASS CEPVSDFPAS FRKSTYWMKM RRIKPAATSH VEGSGGVSAK
110 120 130 140 150
GKRKPRQEED EDYREFPQKK HKLYGRKQRP KTQPNPKSQA RRIRKEPPVY
160 170 180 190 200
AAGSLEEQWY LEIVDKGSVS CPTCQAVGRK TIEGLKKHME NCKQEMFTCH
210 220 230 240 250
HCGKQLRSLA GMKYHVMANH NSLPILKAGD EIDEPSERER LRTVLKRLGK
260 270 280 290 300
LRCMRESCSS SFTSIMGYLY HVRKCGKGAA ELEKMTLKCH HCGKPYRSKA
310 320 330 340 350
GLAYHLRSEH GPISFFPESG QPECLKEMNL ESKSGGRVQR RSAKIAVYHL
360 370 380 390 400
QELASAELAK EWPKRKVLQD LVPDDRKLKY TRPGLPTFSQ EVLHKWKTDI
410 420 430 440 450
KKYHRIQCPN QGCEAVYSSV SGLKAHLGSC TLGNFVAGKY KCLLCQKEFV
460 470 480 490 500
SESGVKYHIN SVHAEDWFVV NPTTTKSFEK LMKIKQRQQE EEKRRQQHRS
510 520 530 540 550
RRSLRRRQQP GIELPETELS LRVGKDQRRN NEELVVSASC KEPEQEPVPA
560
QFQKVKPPKT NHKRGRK
Length:567
Mass (Da):64,682
Last modified:May 5, 2009 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0837E9DB4ED46E75
GO
Isoform 2 (identifier: Q96ME7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-77: Missing.

Show »
Length:490
Mass (Da):56,362
Checksum:iE4222A04C8AD1411
GO
Isoform 3 (identifier: Q96ME7-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     31-31: Missing.
     126-153: Missing.

Show »
Length:538
Mass (Da):61,354
Checksum:i334EE2910BDB1E5D
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G3XAG1G3XAG1_HUMAN
Zinc finger protein 512
ZNF512 hCG_1784442
566Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti24R → S in BAB71348 (PubMed:14702039).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0469331 – 77Missing in isoform 2. 2 PublicationsAdd BLAST77
Alternative sequenceiVSP_04693431Missing in isoform 3. Curated1
Alternative sequenceiVSP_046935126 – 153Missing in isoform 3. CuratedAdd BLAST28

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK057028 mRNA Translation: BAB71348.1
AK294055 mRNA Translation: BAH11661.1
AK299818 mRNA Translation: BAG61687.1
AK316299 mRNA Translation: BAH14670.1
AC074091 Genomic DNA Translation: AAX93199.1
CH471053 Genomic DNA Translation: EAX00562.1
CH471053 Genomic DNA Translation: EAX00564.1
CH471053 Genomic DNA Translation: EAX00565.1
AB058708 mRNA Translation: BAB47434.1
BC043221 mRNA Translation: AAH43221.1
BC093041 mRNA Translation: AAH93041.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS1758.1 [Q96ME7-1]
CCDS59428.1 [Q96ME7-3]
CCDS59429.1 [Q96ME7-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001258215.1, NM_001271286.1 [Q96ME7-3]
NP_001258216.1, NM_001271287.1 [Q96ME7-2]
NP_001258217.1, NM_001271288.1 [Q96ME7-2]
NP_001258218.1, NM_001271289.1
NP_001258247.1, NM_001271318.1 [Q96ME7-2]
NP_115810.2, NM_032434.3 [Q96ME7-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000355467; ENSP00000347648; ENSG00000243943 [Q96ME7-1]
ENST00000413371; ENSP00000395660; ENSG00000243943 [Q96ME7-2]
ENST00000416005; ENSP00000407038; ENSG00000243943 [Q96ME7-3]
ENST00000556601; ENSP00000451572; ENSG00000243943 [Q96ME7-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
84450

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:84450

UCSC genome browser

More...
UCSCi
uc002rla.5, human [Q96ME7-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK057028 mRNA Translation: BAB71348.1
AK294055 mRNA Translation: BAH11661.1
AK299818 mRNA Translation: BAG61687.1
AK316299 mRNA Translation: BAH14670.1
AC074091 Genomic DNA Translation: AAX93199.1
CH471053 Genomic DNA Translation: EAX00562.1
CH471053 Genomic DNA Translation: EAX00564.1
CH471053 Genomic DNA Translation: EAX00565.1
AB058708 mRNA Translation: BAB47434.1
BC043221 mRNA Translation: AAH43221.1
BC093041 mRNA Translation: AAH93041.1
CCDSiCCDS1758.1 [Q96ME7-1]
CCDS59428.1 [Q96ME7-3]
CCDS59429.1 [Q96ME7-2]
RefSeqiNP_001258215.1, NM_001271286.1 [Q96ME7-3]
NP_001258216.1, NM_001271287.1 [Q96ME7-2]
NP_001258217.1, NM_001271288.1 [Q96ME7-2]
NP_001258218.1, NM_001271289.1
NP_001258247.1, NM_001271318.1 [Q96ME7-2]
NP_115810.2, NM_032434.3 [Q96ME7-1]

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2CTDNMR-A142-224[»]
SMRiQ96ME7
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi124088, 128 interactors
IntActiQ96ME7, 90 interactors
MINTiQ96ME7
STRINGi9606.ENSP00000347648

PTM databases

iPTMnetiQ96ME7
PhosphoSitePlusiQ96ME7

Polymorphism and mutation databases

BioMutaiZNF512
DMDMi229462786

Proteomic databases

EPDiQ96ME7
jPOSTiQ96ME7
MassIVEiQ96ME7
MaxQBiQ96ME7
PaxDbiQ96ME7
PeptideAtlasiQ96ME7
PRIDEiQ96ME7
ProteomicsDBi5037
70294
77343 [Q96ME7-1]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
34858, 93 antibodies

Genome annotation databases

EnsembliENST00000355467; ENSP00000347648; ENSG00000243943 [Q96ME7-1]
ENST00000413371; ENSP00000395660; ENSG00000243943 [Q96ME7-2]
ENST00000416005; ENSP00000407038; ENSG00000243943 [Q96ME7-3]
ENST00000556601; ENSP00000451572; ENSG00000243943 [Q96ME7-2]
GeneIDi84450
KEGGihsa:84450
UCSCiuc002rla.5, human [Q96ME7-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
84450
DisGeNETi84450
EuPathDBiHostDB:ENSG00000243943.9

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZNF512
HGNCiHGNC:29380, ZNF512
HPAiENSG00000243943, Low tissue specificity
neXtProtiNX_Q96ME7
OpenTargetsiENSG00000243943
PharmGKBiPA134896861

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
GeneTreeiENSGT00940000158595
HOGENOMiCLU_481412_0_0_1
InParanoidiQ96ME7
OMAiDQRRSNE
OrthoDBi222563at2759
PhylomeDBiQ96ME7
TreeFamiTF331185

Enzyme and pathway databases

PathwayCommonsiQ96ME7

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
84450, 1 hit in 876 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
ZNF512, human
EvolutionaryTraceiQ96ME7

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
84450
PharosiQ96ME7, Tbio

Protein Ontology

More...
PROi
PR:Q96ME7
RNActiQ96ME7, protein

Gene expression databases

BgeeiENSG00000243943, Expressed in female gonad and 205 other tissues
ExpressionAtlasiQ96ME7, baseline and differential
GenevisibleiQ96ME7, HS

Family and domain databases

InterProiView protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF00096, zf-C2H2, 1 hit
SMARTiView protein in SMART
SM00355, ZnF_C2H2, 4 hits
SUPFAMiSSF57667, SSF57667, 5 hits
PROSITEiView protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 3 hits
PS50157, ZINC_FINGER_C2H2_2, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN512_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96ME7
Secondary accession number(s): B4DSM5
, Q53RZ7, Q86XK6, Q96JM0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 15, 2004
Last sequence update: May 5, 2009
Last modified: October 7, 2020
This is version 154 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again