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Entry version 133 (07 Oct 2020)
Sequence version 2 (10 Oct 2003)
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Protein

Protein FAM210B, mitochondrial

Gene

FAM210B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays a role in erythroid differentiation (PubMed:26968549). Involved in cell proliferation and tumor cell growth suppression (PubMed:28594398). Involved in the metabolic reprogramming of cancer cells in a PDK4-dependent manner (PubMed:28594398).2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processDifferentiation, Erythrocyte maturation

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q96KR6

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein FAM210B, mitochondrialCurated
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FAM210BImported
Synonyms:C20orf108
ORF Names:PSEC0265
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 20

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000124098.9

Human Gene Nomenclature Database

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HGNCi
HGNC:16102, FAM210B

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
618722, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q96KR6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei99 – 119HelicalSequence analysisAdd BLAST21
Transmembranei150 – 170HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion outer membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Keywords - Diseasei

Tumor suppressor

Organism-specific databases

DisGeNET

More...
DisGeNETi
116151

Open Targets

More...
OpenTargetsi
ENSG00000124098

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA25647

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q96KR6, Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FAM210B

Domain mapping of disease mutations (DMDM)

More...
DMDMi
41688811

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 58MitochondrionSequence analysis1 PublicationAdd BLAST58
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000007945159 – 192Protein FAM210B, mitochondrialAdd BLAST134

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q96KR6

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q96KR6

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q96KR6

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q96KR6

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q96KR6

PeptideAtlas

More...
PeptideAtlasi
Q96KR6

PRoteomics IDEntifications database

More...
PRIDEi
Q96KR6

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
77108

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
Q96KR6

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q96KR6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q96KR6

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in late erythroblast differentiation stages (PubMed:26968549). Underexpressed in ovarian cancer epithelia cells compared with normal human ovarian surface epithelia (PubMed:28594398).2 Publications

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Up-regulated by the erythroid transcription factor GATA1 (PubMed:26968549).1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSG00000124098, Expressed in bone marrow and 223 other tissues

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
Q96KR6, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q96KR6, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000124098, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Q96KR6
With#Exp.IntAct
ATP6V0B [Q99437]3EBI-18938272,EBI-3904417
ATP6V0C [P27449]3EBI-18938272,EBI-721179
BCL2L13 [Q9BXK5]3EBI-18938272,EBI-747430
BET1 [O15155]3EBI-18938272,EBI-749204
C5orf46 [Q6UWT4]3EBI-18938272,EBI-11986083
CCDC167 [Q9P0B6]3EBI-18938272,EBI-9083477
CD300C [Q08708]3EBI-18938272,EBI-3915344
CLDND2 [Q8NHS1]3EBI-18938272,EBI-11959453
CNIH3 [Q8TBE1]3EBI-18938272,EBI-12208021
CYB5B [O43169]3EBI-18938272,EBI-1058710
CYB5R3 [P00387]3EBI-18938272,EBI-1046040
CYP4F2 [P78329]3EBI-18938272,EBI-1752413
EMP3 [P54852]3EBI-18938272,EBI-3907816
FIS1 [Q9Y3D6]3EBI-18938272,EBI-3385283
GIMAP5 [Q96F15]3EBI-18938272,EBI-6166686
HEXB [P07686]3EBI-18938272,EBI-7133736
HMOX1 [P09601]3EBI-18938272,EBI-2806151
HMOX2 [P30519]3EBI-18938272,EBI-712096
IER3IP1 [Q9Y5U9]3EBI-18938272,EBI-725665
IFITM3 [Q01628]3EBI-18938272,EBI-7932862
LNPEP - isoform 2 [Q9UIQ6-2]3EBI-18938272,EBI-12133176
LPAR3 [Q9UBY5]3EBI-18938272,EBI-12033434
MFF - isoform 5 [Q9GZY8-5]3EBI-18938272,EBI-11956541
MS4A13 [Q5J8X5]3EBI-18938272,EBI-12070086
NINJ2 [Q9NZG7]3EBI-18938272,EBI-10317425
NKG7 [Q16617]3EBI-18938272,EBI-3919611
ORMDL2 [Q53FV1]3EBI-18938272,EBI-11075081
OTOP3 [Q7RTS5]3EBI-18938272,EBI-12853910
PLP2 [Q04941]3EBI-18938272,EBI-608347
PLPP6 [Q8IY26]3EBI-18938272,EBI-11721828
RPRM [Q9NS64]3EBI-18938272,EBI-1052363
RTP2 [Q5QGT7]3EBI-18938272,EBI-10244780
SERP1 [Q9Y6X1]3EBI-18938272,EBI-10329948
SERP2 [Q8N6R1]3EBI-18938272,EBI-749270
SLC16A13 [Q7RTY0]3EBI-18938272,EBI-12243266
SLC30A8 [Q8IWU4]3EBI-18938272,EBI-10262251
SLC35B4 [Q969S0]3EBI-18938272,EBI-10281213
SLC35G1 [Q2M3R5]3EBI-18938272,EBI-13311257
SMCO4 [Q9NRQ5]3EBI-18938272,EBI-8640191
SMIM1 [B2RUZ4]3EBI-18938272,EBI-12188413
STX6 [O43752]3EBI-18938272,EBI-2695795
STX7 [O15400]3EBI-18938272,EBI-3221827
SYNJ2BP [P57105]3EBI-18938272,EBI-1049004
TF [P02787]3EBI-18938272,EBI-714319
TFRC [P02786]3EBI-18938272,EBI-355727
TIMM23 [O14925]3EBI-18938272,EBI-1047996
TIMMDC1 [Q9NPL8]3EBI-18938272,EBI-6268651
TMEM107 [Q6UX40]3EBI-18938272,EBI-12845616
TMEM11 [P17152]3EBI-18938272,EBI-723946
TMEM140 [Q9NV12]3EBI-18938272,EBI-2844246
TMEM187 [Q14656]3EBI-18938272,EBI-13046724
TMEM19 [Q96HH6]3EBI-18938272,EBI-741829
UBE2J1 [Q9Y385]3EBI-18938272,EBI-988826
VAMP1 - isoform 2 [P23763-3]3EBI-18938272,EBI-12097582
VAMP3 [Q15836]3EBI-18938272,EBI-722343
VAMP4 [O75379]3EBI-18938272,EBI-744953
VKORC1 [Q9BQB6]3EBI-18938272,EBI-6256462
YIF1A [O95070]3EBI-18938272,EBI-2799703
ZDHHC21 [Q8IVQ6]3EBI-18938272,EBI-2849773

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
125482, 76 interactors

Protein interaction database and analysis system

More...
IntActi
Q96KR6, 68 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000360437

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q96KR6, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini80 – 191DUF1279Add BLAST112

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the FAM210 family.Curated

Keywords - Domaini

Transit peptide, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG4526, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156134

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_1414738_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q96KR6

Identification of Orthologs from Complete Genome Data

More...
OMAi
DCRGRQD

Database of Orthologous Groups

More...
OrthoDBi
1506373at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q96KR6

TreeFam database of animal gene trees

More...
TreeFami
TF313283

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR009688, DUF1279

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF06916, DUF1279, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q96KR6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAGLLALLGP AGRVGARVRP RATWLLGATA PCAPPPLALA LLPPRLDARL
60 70 80 90 100
LRTARGDCRG HQDPSQATGT TGSSVSCTEE KKQSKSQQLK KIFQEYGTVG
110 120 130 140 150
VSLHIGISLI SLGIFYMVVS SGVDMPAILL KLGFKESLVQ SKMAAGTSTF
160 170 180 190
VVAYAIHKLF APVRISITLV SVPLIVRYFR KVGFFKPPAA KP
Length:192
Mass (Da):20,424
Last modified:October 10, 2003 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFE895D3E5FB042D2
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H0Y456H0Y456_HUMAN
Protein FAM210B, mitochondrial
FAM210B
52Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti36P → L in CAC67490 (Ref. 1) Curated1
Sequence conflicti161A → V in AAH17725 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_033763126P → S. Corresponds to variant dbSNP:rs6099115Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AJ311123 mRNA Translation: CAC67490.1
AK075565 mRNA Translation: BAC11704.1
AK314768 mRNA Translation: BAG37306.1
AL121914 Genomic DNA No translation available.
CH471077 Genomic DNA Translation: EAW75564.1
CH471077 Genomic DNA Translation: EAW75565.1
BC017725 mRNA Translation: AAH17725.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS13450.1

NCBI Reference Sequences

More...
RefSeqi
NP_543011.2, NM_080821.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000371384; ENSP00000360437; ENSG00000124098

Database of genes from NCBI RefSeq genomes

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GeneIDi
116151

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:116151

UCSC genome browser

More...
UCSCi
uc002xxc.4, human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ311123 mRNA Translation: CAC67490.1
AK075565 mRNA Translation: BAC11704.1
AK314768 mRNA Translation: BAG37306.1
AL121914 Genomic DNA No translation available.
CH471077 Genomic DNA Translation: EAW75564.1
CH471077 Genomic DNA Translation: EAW75565.1
BC017725 mRNA Translation: AAH17725.1
CCDSiCCDS13450.1
RefSeqiNP_543011.2, NM_080821.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi125482, 76 interactors
IntActiQ96KR6, 68 interactors
STRINGi9606.ENSP00000360437

PTM databases

iPTMnetiQ96KR6
PhosphoSitePlusiQ96KR6

Polymorphism and mutation databases

BioMutaiFAM210B
DMDMi41688811

Proteomic databases

EPDiQ96KR6
jPOSTiQ96KR6
MassIVEiQ96KR6
MaxQBiQ96KR6
PaxDbiQ96KR6
PeptideAtlasiQ96KR6
PRIDEiQ96KR6
ProteomicsDBi77108
TopDownProteomicsiQ96KR6

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
63338, 26 antibodies

Genome annotation databases

EnsembliENST00000371384; ENSP00000360437; ENSG00000124098
GeneIDi116151
KEGGihsa:116151
UCSCiuc002xxc.4, human

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
116151
DisGeNETi116151
EuPathDBiHostDB:ENSG00000124098.9

GeneCards: human genes, protein and diseases

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GeneCardsi
FAM210B
HGNCiHGNC:16102, FAM210B
HPAiENSG00000124098, Low tissue specificity
MIMi618722, gene
neXtProtiNX_Q96KR6
OpenTargetsiENSG00000124098
PharmGKBiPA25647

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG4526, Eukaryota
GeneTreeiENSGT00940000156134
HOGENOMiCLU_1414738_0_0_1
InParanoidiQ96KR6
OMAiDCRGRQD
OrthoDBi1506373at2759
PhylomeDBiQ96KR6
TreeFamiTF313283

Enzyme and pathway databases

PathwayCommonsiQ96KR6

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
116151, 2 hits in 850 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
FAM210B, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
116151
PharosiQ96KR6, Tbio

Protein Ontology

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PROi
PR:Q96KR6
RNActiQ96KR6, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000124098, Expressed in bone marrow and 223 other tissues
ExpressionAtlasiQ96KR6, baseline and differential
GenevisibleiQ96KR6, HS

Family and domain databases

InterProiView protein in InterPro
IPR009688, DUF1279
PfamiView protein in Pfam
PF06916, DUF1279, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF210B_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96KR6
Secondary accession number(s): B2RBQ9
, E1P5Y7, Q8WVN2, Q9BYL6, Q9H418
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 10, 2003
Last sequence update: October 10, 2003
Last modified: October 7, 2020
This is version 133 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. SIMILARITY comments
    Index of protein domains and families
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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