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UniProtKB - Q96KC8 (DNJC1_HUMAN)

Entry version 176 (25 May 2022)
Sequence version 1 (01 Dec 2001)
Previous versions | rss
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Protein

DnaJ homolog subfamily C member 1

Gene

DNAJC1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May modulate protein synthesis.

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionChaperone, DNA-binding

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q96KC8

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		Q96KC8

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
DnaJ homolog subfamily C member 1
Alternative name(s):
DnaJ protein homolog MTJ1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:DNAJC1
Synonyms:HTJ1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:20090, DNAJC1

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		611207, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q96KC8

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000136770

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini48 – 153LumenalBy similarityAdd BLAST106
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei154 – 174HelicalSequence analysisAdd BLAST21
Topological domaini175 – 554CytoplasmicBy similarityAdd BLAST380

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane, Microsome, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		64215

Open Targets

More...OpenTargetsi		ENSG00000136770

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA128394706

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q96KC8, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		DNAJC1

Domain mapping of disease mutations (DMDM)

More...DMDMi		27805464

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 47Sequence analysisAdd BLAST47
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000007104248 – 554DnaJ homolog subfamily C member 1Add BLAST507

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei381PhosphoserineCombined sources1
Modified residuei430PhosphoserineCombined sources1
Modified residuei479PhosphoserineCombined sources1
Modified residuei480PhosphoserineCombined sources1
Modified residuei484PhosphoserineCombined sources1
Modified residuei492PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q96KC8

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q96KC8

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q96KC8

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q96KC8

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q96KC8

PeptideAtlas

More...PeptideAtlasi		Q96KC8

PRoteomics IDEntifications database

More...PRIDEi		Q96KC8

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		77059

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q96KC8

MetOSite database of methionine sulfoxide sites

More...MetOSitei		Q96KC8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q96KC8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000136770, Expressed in secondary oocyte and 241 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q96KC8, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q96KC8, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000136770, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts (via J domain) with HSPA5.

Interacts (via cytosolic domain) with ribosomes (By similarity).

Interacts (via SANT 2 domain) with SERPINA3; the interaction delays the formation of the covalent inhibitory complex SERPINA3-chymotrypsin, but does not alter the catalytic activity of SERPINA3.

Interacts (via SANT 2 domain) with ITIH4 (via C-terminus); the interaction protects ITIH4 against in vitro cleavage by kallikrein.

By similarity1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		122105, 359 interactors

Protein interaction database and analysis system

More...IntActi		Q96KC8, 36 interactors

Molecular INTeraction database

More...MINTi		Q96KC8

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000366179

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q96KC8, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1554
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

AlphaFold Protein Structure Database

More...AlphaFoldDBi		Q96KC8

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q96KC8

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...EvolutionaryTracei		Q96KC8

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini65 – 129JPROSITE-ProRule annotationAdd BLAST65
Domaini325 – 379SANT 1PROSITE-ProRule annotationAdd BLAST55
Domaini492 – 547SANT 2PROSITE-ProRule annotationAdd BLAST56

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni392 – 500DisorderedSequence analysisAdd BLAST109

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi392 – 409Polar residuesSequence analysisAdd BLAST18
Compositional biasi434 – 494Basic and acidic residuesSequence analysisAdd BLAST61

Keywords - Domaini

Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0724, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000156678

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_036945_2_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q96KC8

Identification of Orthologs from Complete Genome Data

More...OMAi		KEECVAR

Database of Orthologous Groups

More...OrthoDBi		972481at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q96KC8

TreeFam database of animal gene trees

More...TreeFami		TF105161

Family and domain databases

Conserved Domains Database

More...CDDi		cd06257, DnaJ, 1 hit
cd00167, SANT, 2 hits

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.287.110, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR001623, DnaJ_domain
IPR018253, DnaJ_domain_CS
IPR009057, Homeobox-like_sf
IPR036869, J_dom_sf
IPR017930, Myb_dom
IPR001005, SANT/Myb
IPR017884, SANT_dom

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00226, DnaJ, 1 hit
PF00249, Myb_DNA-binding, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00625, JDOMAIN

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00271, DnaJ, 1 hit
SM00717, SANT, 2 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF46565, SSF46565, 1 hit
SSF46689, SSF46689, 2 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00636, DNAJ_1, 1 hit
PS50076, DNAJ_2, 1 hit
PS51293, SANT, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q96KC8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTAPCSQPAQ LPGRRQLGLV PFPPPPPRTP LLWLLLLLLA AVAPARGWES 
        60         70         80         90        100
GDLELFDLVE EVQLNFYQFL GVQQDASSAD IRKAYRKLSL TLHPDKNKDE 
       110        120        130        140        150
NAETQFRQLV AIYEVLKDDE RRQRYDDILI NGLPDWRQPV FYYRRVRKMS 
       160        170        180        190        200
NAELALLLFI ILTVGHYAVV WSIYLEKQLD ELLSRKKREK KKKTGSKSVD 
       210        220        230        240        250
VSKLGASEKN ERLLMKPQWH DLLPCKLGIW FCLTLKALPH LIQDAGQFYA 
       260        270        280        290        300
KYKETRLKEK EDALTRTELE TLQKQKKVKK PKPEFPVYTP LETTYIQSYD 
       310        320        330        340        350
HGTSIEEIEE QMDDWLENRN RTQKKQAPEW TEEDLSQLTR SMVKFPGGTP 
       360        370        380        390        400
GRWEKIAHEL GRSVTDVTTK AKQLKDSVTC SPGMVRLSEL KSTVQNSRPI 
       410        420        430        440        450
KTATTLPDDM ITQREDAEGV AAEEEQEGDS GEQETGATDA RPRRRKPARL 
       460        470        480        490        500
LEATAKPEPE EKSRAKRQKD FDIAEQNESS DEESLRKERA RSAEEPWTQN 
       510        520        530        540        550
QQKLLELALQ QYPRGSSDRW DKIARCVPSK SKEDCIARYK LLVELVQKKK 

QAKS
Length:554
Mass (Da):63,883
Last modified:December 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i65EAAB16C65E2B46
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5T1X2Q5T1X2_HUMAN
DnaJ homolog subfamily C member 1
DNAJC1
109Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AY225122 mRNA Translation: AAP50497.1
AK026062 mRNA Translation: BAB15343.1
AK027263 mRNA Translation: BAB55004.1
EF444973 Genomic DNA Translation: ACA05978.1
EF444973 Genomic DNA Translation: ACA05979.1
AL445431 Genomic DNA No translation available.
AL359697 Genomic DNA No translation available.
BC110894 mRNA Translation: AAI10895.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS7136.1

NCBI Reference Sequences

More...RefSeqi		NP_071760.2, NM_022365.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000376980.8; ENSP00000366179.3; ENSG00000136770.11

Database of genes from NCBI RefSeq genomes

More...GeneIDi		64215

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:64215

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000376980.8; ENSP00000366179.3; NM_022365.4; NP_071760.2

UCSC genome browser

More...UCSCi		uc001irc.4, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY225122 mRNA Translation: AAP50497.1
AK026062 mRNA Translation: BAB15343.1
AK027263 mRNA Translation: BAB55004.1
EF444973 Genomic DNA Translation: ACA05978.1
EF444973 Genomic DNA Translation: ACA05979.1
AL445431 Genomic DNA No translation available.
AL359697 Genomic DNA No translation available.
BC110894 mRNA Translation: AAI10895.1
CCDSiCCDS7136.1
RefSeqiNP_071760.2, NM_022365.3

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2CQQNMR-A327-385[»]
2CQRNMR-A484-543[»]
AlphaFoldDBiQ96KC8
SMRiQ96KC8
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi122105, 359 interactors
IntActiQ96KC8, 36 interactors
MINTiQ96KC8
STRINGi9606.ENSP00000366179

PTM databases

iPTMnetiQ96KC8
MetOSiteiQ96KC8
PhosphoSitePlusiQ96KC8

Genetic variation databases

BioMutaiDNAJC1
DMDMi27805464

Proteomic databases

EPDiQ96KC8
jPOSTiQ96KC8
MassIVEiQ96KC8
MaxQBiQ96KC8
PaxDbiQ96KC8
PeptideAtlasiQ96KC8
PRIDEiQ96KC8
ProteomicsDBi77059

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		2466, 87 antibodies from 24 providers

The DNASU plasmid repository

More...DNASUi		64215

Genome annotation databases

EnsembliENST00000376980.8; ENSP00000366179.3; ENSG00000136770.11
GeneIDi64215
KEGGihsa:64215
MANE-SelectiENST00000376980.8; ENSP00000366179.3; NM_022365.4; NP_071760.2
UCSCiuc001irc.4, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		64215
DisGeNETi64215

GeneCards: human genes, protein and diseases

More...GeneCardsi		DNAJC1
HGNCiHGNC:20090, DNAJC1
HPAiENSG00000136770, Low tissue specificity
MIMi611207, gene
neXtProtiNX_Q96KC8
OpenTargetsiENSG00000136770
PharmGKBiPA128394706
VEuPathDBiHostDB:ENSG00000136770

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG0724, Eukaryota
GeneTreeiENSGT00940000156678
HOGENOMiCLU_036945_2_0_1
InParanoidiQ96KC8
OMAiKEECVAR
OrthoDBi972481at2759
PhylomeDBiQ96KC8
TreeFamiTF105161

Enzyme and pathway databases

PathwayCommonsiQ96KC8
SignaLinkiQ96KC8

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		64215, 5 hits in 1098 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		DNAJC1, human
EvolutionaryTraceiQ96KC8

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		DNAJC1

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		64215
PharosiQ96KC8, Tbio

Protein Ontology

More...PROi		PR:Q96KC8
RNActiQ96KC8, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000136770, Expressed in secondary oocyte and 241 other tissues
ExpressionAtlasiQ96KC8, baseline and differential
GenevisibleiQ96KC8, HS

Family and domain databases

CDDicd06257, DnaJ, 1 hit
cd00167, SANT, 2 hits
Gene3Di1.10.287.110, 1 hit
InterProiView protein in InterPro
IPR001623, DnaJ_domain
IPR018253, DnaJ_domain_CS
IPR009057, Homeobox-like_sf
IPR036869, J_dom_sf
IPR017930, Myb_dom
IPR001005, SANT/Myb
IPR017884, SANT_dom
PfamiView protein in Pfam
PF00226, DnaJ, 1 hit
PF00249, Myb_DNA-binding, 1 hit
PRINTSiPR00625, JDOMAIN
SMARTiView protein in SMART
SM00271, DnaJ, 1 hit
SM00717, SANT, 2 hits
SUPFAMiSSF46565, SSF46565, 1 hit
SSF46689, SSF46689, 2 hits
PROSITEiView protein in PROSITE
PS00636, DNAJ_1, 1 hit
PS50076, DNAJ_2, 1 hit
PS51293, SANT, 2 hits

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDNJC1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96KC8
Secondary accession number(s): B0YIZ8, Q5VX89, Q9H6B8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 17, 2003
Last sequence update: December 1, 2001
Last modified: May 25, 2022
This is version 176 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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