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Entry version 138 (16 Oct 2019)
Sequence version 1 (01 Dec 2001)
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Protein

Cleft lip and palate transmembrane protein 1-like protein

Gene

CLPTM1L

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Enhances cisplatin-mediated apoptosis, when overexpressed.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processApoptosis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cleft lip and palate transmembrane protein 1-like protein
Short name:
CLPTM1-like protein
Alternative name(s):
Cisplatin resistance-related protein 9
Short name:
CRR9p
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CLPTM1L
Synonyms:CRR9
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:24308 CLPTM1L

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
612585 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q96KA5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 10CytoplasmicSequence analysis10
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei11 – 31HelicalSequence analysisAdd BLAST21
Topological domaini32 – 284ExtracellularSequence analysisAdd BLAST253
Transmembranei285 – 305HelicalSequence analysisAdd BLAST21
Topological domaini306 – 324CytoplasmicSequence analysisAdd BLAST19
Transmembranei325 – 342HelicalSequence analysisAdd BLAST18
Topological domaini343 – 346ExtracellularSequence analysis4
Transmembranei347 – 364HelicalSequence analysisAdd BLAST18
Topological domaini365 – 402CytoplasmicSequence analysisAdd BLAST38
Transmembranei403 – 423HelicalSequence analysisAdd BLAST21
Topological domaini424 – 428ExtracellularSequence analysis5
Transmembranei429 – 449HelicalSequence analysisAdd BLAST21
Topological domaini450 – 538CytoplasmicSequence analysisAdd BLAST89

Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
81037

Open Targets

More...
OpenTargetsi
ENSG00000049656

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA147358156

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q96KA5

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
CLPTM1L

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74732209

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003313001 – 538Cleft lip and palate transmembrane protein 1-like proteinAdd BLAST538

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi91N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi101N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi229N-linked (GlcNAc...) asparagine1 Publication1

Keywords - PTMi

Glycoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q96KA5

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q96KA5

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q96KA5

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q96KA5

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q96KA5

PeptideAtlas

More...
PeptideAtlasi
Q96KA5

PRoteomics IDEntifications database

More...
PRIDEi
Q96KA5

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
77054 [Q96KA5-1]
77055 [Q96KA5-2]

PTM databases

GlyConnect protein glycosylation platform

More...
GlyConnecti
1117

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q96KA5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q96KA5

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q96KA5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Up-regulated by cisplatin.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000049656 Expressed in 196 organ(s), highest expression level in kidney epithelium

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q96KA5 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q96KA5 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA014791

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
123354, 28 interactors

Protein interaction database and analysis system

More...
IntActi
Q96KA5, 27 interactors

Molecular INTeraction database

More...
MINTi
Q96KA5

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000313854

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CLPTM1 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2489 Eukaryota
ENOG410XPEV LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00530000063461

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000201405

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q96KA5

Identification of Orthologs from Complete Genome Data

More...
OMAi
GMRYLSY

Database of Orthologous Groups

More...
OrthoDBi
1106937at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q96KA5

TreeFam database of animal gene trees

More...
TreeFami
TF318501

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008429 CLPTM1
IPR030434 CLPTM1L

The PANTHER Classification System

More...
PANTHERi
PTHR21347 PTHR21347, 1 hit
PTHR21347:SF0 PTHR21347:SF0, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05602 CLPTM1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q96KA5-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MWSGRSSFTS LVVGVFVVYV VHTCWVMYGI VYTRPCSGDA NCIQPYLARR
60 70 80 90 100
PKLQLSVYTT TRSHLGAENN IDLVLNVEDF DVESKFERTV NVSVPKKTRN
110 120 130 140 150
NGTLYAYIFL HHAGVLPWHD GKQVHLVSPL TTYMVPKPEE INLLTGESDT
160 170 180 190 200
QQIEAEKKPT SALDEPVSHW RPRLALNVMA DNFVFDGSSL PADVHRYMKM
210 220 230 240 250
IQLGKTVHYL PILFIDQLSN RVKDLMVINR STTELPLTVS YDKVSLGRLR
260 270 280 290 300
FWIHMQDAVY SLQQFGFSEK DADEVKGIFV DTNLYFLALT FFVAAFHLLF
310 320 330 340 350
DFLAFKNDIS FWKKKKSMIG MSTKAVLWRC FSTVVIFLFL LDEQTSLLVL
360 370 380 390 400
VPAGVGAAIE LWKVKKALKM TIFWRGLMPE FQFGTYSESE RKTEEYDTQA
410 420 430 440 450
MKYLSYLLYP LCVGGAVYSL LNIKYKSWYS WLINSFVNGV YAFGFLFMLP
460 470 480 490 500
QLFVNYKLKS VAHLPWKAFT YKAFNTFIDD VFAFIITMPT SHRLACFRDD
510 520 530
VVFLVYLYQR WLYPVDKRRV NEFGESYEEK ATRAPHTD
Length:538
Mass (Da):62,229
Last modified:December 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA83FF068AED01FC7
GO
Isoform 2 (identifier: Q96KA5-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     325-360: Missing.

Show »
Length:502
Mass (Da):58,356
Checksum:iF336609A093D72AB
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G5E9Z2G5E9Z2_HUMAN
Cisplatin resistance related protei...
CLPTM1L CRR9, hCG_1810932
369Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAB20083 differs from that shown. Reason: Erroneous initiation.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_042754313K → N in a breast cancer sample; somatic mutation. 1 Publication1
Natural variantiVAR_042755537T → M. Corresponds to variant dbSNP:rs33955038Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_033157325 – 360Missing in isoform 2. 1 PublicationAdd BLAST36

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK027306 mRNA Translation: BAB55030.1
CH471102 Genomic DNA Translation: EAX08162.1
CH471102 Genomic DNA Translation: EAX08163.1
BC016399 mRNA Translation: AAH16399.1
BC025305 mRNA Translation: AAH25305.1
AB045223 mRNA Translation: BAB20083.1 Different initiation.
AL832953 mRNA Translation: CAH56333.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS3862.1 [Q96KA5-1]

Protein sequence database of the Protein Information Resource

More...
PIRi
JC7599

NCBI Reference Sequences

More...
RefSeqi
NP_110409.2, NM_030782.4 [Q96KA5-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000320895; ENSP00000313854; ENSG00000049656 [Q96KA5-1]
ENST00000620010; ENSP00000480372; ENSG00000274811 [Q96KA5-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
81037

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:81037

UCSC genome browser

More...
UCSCi
uc003jch.4 human [Q96KA5-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK027306 mRNA Translation: BAB55030.1
CH471102 Genomic DNA Translation: EAX08162.1
CH471102 Genomic DNA Translation: EAX08163.1
BC016399 mRNA Translation: AAH16399.1
BC025305 mRNA Translation: AAH25305.1
AB045223 mRNA Translation: BAB20083.1 Different initiation.
AL832953 mRNA Translation: CAH56333.1
CCDSiCCDS3862.1 [Q96KA5-1]
PIRiJC7599
RefSeqiNP_110409.2, NM_030782.4 [Q96KA5-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi123354, 28 interactors
IntActiQ96KA5, 27 interactors
MINTiQ96KA5
STRINGi9606.ENSP00000313854

PTM databases

GlyConnecti1117
iPTMnetiQ96KA5
PhosphoSitePlusiQ96KA5
SwissPalmiQ96KA5

Polymorphism and mutation databases

BioMutaiCLPTM1L
DMDMi74732209

Proteomic databases

EPDiQ96KA5
jPOSTiQ96KA5
MassIVEiQ96KA5
MaxQBiQ96KA5
PaxDbiQ96KA5
PeptideAtlasiQ96KA5
PRIDEiQ96KA5
ProteomicsDBi77054 [Q96KA5-1]
77055 [Q96KA5-2]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
81037

Genome annotation databases

EnsembliENST00000320895; ENSP00000313854; ENSG00000049656 [Q96KA5-1]
ENST00000620010; ENSP00000480372; ENSG00000274811 [Q96KA5-1]
GeneIDi81037
KEGGihsa:81037
UCSCiuc003jch.4 human [Q96KA5-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
81037
DisGeNETi81037

GeneCards: human genes, protein and diseases

More...
GeneCardsi
CLPTM1L
HGNCiHGNC:24308 CLPTM1L
HPAiHPA014791
MIMi612585 gene
neXtProtiNX_Q96KA5
OpenTargetsiENSG00000049656
PharmGKBiPA147358156

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG2489 Eukaryota
ENOG410XPEV LUCA
GeneTreeiENSGT00530000063461
HOGENOMiHOG000201405
InParanoidiQ96KA5
OMAiGMRYLSY
OrthoDBi1106937at2759
PhylomeDBiQ96KA5
TreeFamiTF318501

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
CLPTM1L human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
CLPTM1L

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
81037
PharosiQ96KA5

Protein Ontology

More...
PROi
PR:Q96KA5

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000049656 Expressed in 196 organ(s), highest expression level in kidney epithelium
ExpressionAtlasiQ96KA5 baseline and differential
GenevisibleiQ96KA5 HS

Family and domain databases

InterProiView protein in InterPro
IPR008429 CLPTM1
IPR030434 CLPTM1L
PANTHERiPTHR21347 PTHR21347, 1 hit
PTHR21347:SF0 PTHR21347:SF0, 1 hit
PfamiView protein in Pfam
PF05602 CLPTM1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCLP1L_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96KA5
Secondary accession number(s): D3DTC1
, Q658W6, Q7LG29, Q96AZ0, Q9H3N4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: December 1, 2001
Last modified: October 16, 2019
This is version 138 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 5
    Human chromosome 5: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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