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Entry version 142 (02 Jun 2021)
Sequence version 1 (01 Dec 2001)
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Protein

Zinc finger CCCH domain-containing protein 10

Gene

ZC3H10

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Specific regulator of miRNA biogenesis. Binds, via the C3H1-type zinc finger domains, to the binding motif 5'-GCAGCGC-3' on microRNA pri-MIR143 and negatively regulates the processing to mature microRNA.

1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri36 – 63C3H1-type 1PROSITE-ProRule annotationAdd BLAST28
Zinc fingeri73 – 99C3H1-type 2PROSITE-ProRule annotationAdd BLAST27
Zinc fingeri134 – 161C3H1-type 3PROSITE-ProRule annotationAdd BLAST28

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRNA-binding
LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q96K80

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger CCCH domain-containing protein 10
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZC3H10
Synonyms:ZC3HDC10
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:25893, ZC3H10

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q96K80

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000135482.6

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi50 – 56CKRGKRC → SKRGKRS: Abolishes binding to pri-MIR143. 1 Publication7
Mutagenesisi87 – 92CSRPNC → SSRPNS: Abolishes binding to pri-MIR143. 1 Publication6
Mutagenesisi148 – 154CQRGAKC → SQRGAKS: Reduces binding to pri-MIR143. 1 Publication7

Organism-specific databases

DisGeNET

More...
DisGeNETi
84872

Open Targets

More...
OpenTargetsi
ENSG00000135482

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142670534

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q96K80, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZC3H10

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74760908

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002811451 – 434Zinc finger CCCH domain-containing protein 10Add BLAST434

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei185Omega-N-methylarginineBy similarity1
Modified residuei186Omega-N-methylarginineBy similarity1

Keywords - PTMi

Methylation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q96K80

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q96K80

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q96K80

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q96K80

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q96K80

PeptideAtlas

More...
PeptideAtlasi
Q96K80

PRoteomics IDEntifications database

More...
PRIDEi
Q96K80

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
77051

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q96K80

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q96K80

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000135482, Expressed in prostate gland and 198 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q96K80, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q96K80, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000135482, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details
Q96K80
With#Exp.IntAct
AOC1 [P19801]3EBI-742550,EBI-12826295
APPBP2 [Q92624]3EBI-742550,EBI-743771
ARID5A [Q03989]3EBI-742550,EBI-948603
ATXN1 [P54253]7EBI-742550,EBI-930964
BOLL - isoform 4 [Q8N9W6-4]3EBI-742550,EBI-11983447
C10orf55 [Q5SWW7]3EBI-742550,EBI-12809220
C19orf54 - isoform 3 [Q5BKX5-3]3EBI-742550,EBI-11976299
CRX [O43186]3EBI-742550,EBI-748171
DAB1 [O75553]3EBI-742550,EBI-7875264
DAZAP2 [Q15038]7EBI-742550,EBI-724310
FAM168B - isoform 2 [A1KXE4-2]3EBI-742550,EBI-12193763
FOSB [P53539]3EBI-742550,EBI-2806743
FOXH1 [O75593]3EBI-742550,EBI-1759806
INTS11 [Q5TA45]3EBI-742550,EBI-748258
KLHDC7B [Q96G42]3EBI-742550,EBI-9478422
KRTAP19-1 [Q8IUB9]3EBI-742550,EBI-12811111
KRTAP6-1 [Q3LI64]3EBI-742550,EBI-12111050
KRTAP6-2 [Q3LI66]3EBI-742550,EBI-11962084
KRTAP8-1 [Q8IUC2]3EBI-742550,EBI-10261141
LASP1 - isoform 2 [Q14847-2]3EBI-742550,EBI-9088686
MSX2 [P35548]3EBI-742550,EBI-6447480
NCS1 [P62166]3EBI-742550,EBI-746987
NFYA - isoform Short [P23511-2]3EBI-742550,EBI-11061759
OTX2 - isoform 2 [P32243-2]3EBI-742550,EBI-9087860
OXER1 [Q8TDS5]3EBI-742550,EBI-12813389
PIAS2 - isoform PIAS2-alpha [O75928-2]3EBI-742550,EBI-348567
PICALM - isoform 3 [Q13492-3]3EBI-742550,EBI-11031437
PLA2G10 [O15496]3EBI-742550,EBI-726466
POU2F1 - isoform 6 [P14859-6]3EBI-742550,EBI-11526590
PRR20C [P86479]3EBI-742550,EBI-10172814
PRR20D [P86480]3EBI-742550,EBI-12754095
RBM38 [Q9H0Z9]3EBI-742550,EBI-2840723
RBPMS [Q93062]4EBI-742550,EBI-740322
RBPMS2 [Q6ZRY4]3EBI-742550,EBI-11987469
RNF4 [P78317]3EBI-742550,EBI-2340927
STAM2 [O75886]3EBI-742550,EBI-373258
TENT5B [Q96A09]3EBI-742550,EBI-752030
TEX37 [Q96LM6]3EBI-742550,EBI-743976
UBE2I [Q7KZS0]3EBI-742550,EBI-10180829

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
124317, 55 interactors

Protein interaction database and analysis system

More...
IntActi
Q96K80, 44 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000257940

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q96K80, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q96K80

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 37DisorderedSequence analysisAdd BLAST37
Regioni196 – 217DisorderedSequence analysisAdd BLAST22
Regioni314 – 362DisorderedSequence analysisAdd BLAST49

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili234 – 280Sequence analysisAdd BLAST47

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi196 – 216Basic and acidic residuesSequence analysisAdd BLAST21
Compositional biasi340 – 361Pro residuesSequence analysisAdd BLAST22

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri36 – 63C3H1-type 1PROSITE-ProRule annotationAdd BLAST28
Zinc fingeri73 – 99C3H1-type 2PROSITE-ProRule annotationAdd BLAST27
Zinc fingeri134 – 161C3H1-type 3PROSITE-ProRule annotationAdd BLAST28

Keywords - Domaini

Coiled coil, Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2494, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000182897

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_039343_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q96K80

Identification of Orthologs from Complete Genome Data

More...
OMAi
KDYEYEP

Database of Orthologous Groups

More...
OrthoDBi
1441991at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q96K80

TreeFam database of animal gene trees

More...
TreeFami
TF321931

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000571, Znf_CCCH

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00642, zf-CCCH, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00356, ZnF_C3H1, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50103, ZF_C3H1, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q96K80-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPDRDSYANG TGSSGGGPGG GGSEEASGAG VGSGGASSDA ICRDFLRNVC
60 70 80 90 100
KRGKRCRYRH PDMSEVSNLG VSKNEFIFCH DFQNKECSRP NCRFIHGSKE
110 120 130 140 150
DEDGYKKTGE LPPRLRQKVA AGLGLSPADL PNGKEEVPIC RDFLKGDCQR
160 170 180 190 200
GAKCKFRHLQ RDFEFDARGG GGTGGGSTGS VLPGRRHDLY DIYDLPDRGF
210 220 230 240 250
EDHEPGPKRR RGGCCPPDGP HFESYEYSLA PPRGVECRLL EEENAMLRKR
260 270 280 290 300
VEELKKQVSN LLATNEVLLE QNAQFRNQAK VITLSSTAPA TEQTLAPTVG
310 320 330 340 350
TVATFNHGIA QTHTTLSSQA LQPRPVSQQE LVAPAGAPAA PPTNAAPPAA
360 370 380 390 400
PPPPPPHLTP EITPLSAALA QTIAQGMAPP PVSMAPVAVS VAPVAPVAVS
410 420 430
MAQPLAGITM SHTTTPMVTY PIASQSMRIT AMPH
Length:434
Mass (Da):46,052
Last modified:December 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE4B24A526F3A573B
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F8VQT2F8VQT2_HUMAN
Zinc finger CCCH domain-containing ...
ZC3H10
79Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8VYY3F8VYY3_HUMAN
Zinc finger CCCH domain-containing ...
ZC3H10
88Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8VSG0F8VSG0_HUMAN
Zinc finger CCCH domain-containing ...
ZC3H10
45Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK027357 mRNA Translation: BAB55059.1
BC018708 mRNA Translation: AAH18708.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS8903.1

NCBI Reference Sequences

More...
RefSeqi
NP_001290053.1, NM_001303124.1
NP_001290054.1, NM_001303125.1
NP_116175.1, NM_032786.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000257940; ENSP00000257940; ENSG00000135482

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
84872

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:84872

UCSC genome browser

More...
UCSCi
uc001sjp.2, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK027357 mRNA Translation: BAB55059.1
BC018708 mRNA Translation: AAH18708.1
CCDSiCCDS8903.1
RefSeqiNP_001290053.1, NM_001303124.1
NP_001290054.1, NM_001303125.1
NP_116175.1, NM_032786.2

3D structure databases

SMRiQ96K80
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi124317, 55 interactors
IntActiQ96K80, 44 interactors
STRINGi9606.ENSP00000257940

PTM databases

iPTMnetiQ96K80
PhosphoSitePlusiQ96K80

Genetic variation databases

BioMutaiZC3H10
DMDMi74760908

Proteomic databases

EPDiQ96K80
jPOSTiQ96K80
MassIVEiQ96K80
MaxQBiQ96K80
PaxDbiQ96K80
PeptideAtlasiQ96K80
PRIDEiQ96K80
ProteomicsDBi77051

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
27922, 123 antibodies

The DNASU plasmid repository

More...
DNASUi
84872

Genome annotation databases

EnsembliENST00000257940; ENSP00000257940; ENSG00000135482
GeneIDi84872
KEGGihsa:84872
UCSCiuc001sjp.2, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
84872
DisGeNETi84872

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZC3H10
HGNCiHGNC:25893, ZC3H10
HPAiENSG00000135482, Low tissue specificity
neXtProtiNX_Q96K80
OpenTargetsiENSG00000135482
PharmGKBiPA142670534
VEuPathDBiHostDB:ENSG00000135482.6

GenAtlas: human gene database

More...
GenAtlasi
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Phylogenomic databases

eggNOGiKOG2494, Eukaryota
GeneTreeiENSGT00950000182897
HOGENOMiCLU_039343_0_0_1
InParanoidiQ96K80
OMAiKDYEYEP
OrthoDBi1441991at2759
PhylomeDBiQ96K80
TreeFamiTF321931

Enzyme and pathway databases

PathwayCommonsiQ96K80

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
84872, 61 hits in 999 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
84872
PharosiQ96K80, Tbio

Protein Ontology

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PROi
PR:Q96K80
RNActiQ96K80, protein

Gene expression databases

BgeeiENSG00000135482, Expressed in prostate gland and 198 other tissues
ExpressionAtlasiQ96K80, baseline and differential
GenevisibleiQ96K80, HS

Family and domain databases

InterProiView protein in InterPro
IPR000571, Znf_CCCH
PfamiView protein in Pfam
PF00642, zf-CCCH, 2 hits
SMARTiView protein in SMART
SM00356, ZnF_C3H1, 3 hits
PROSITEiView protein in PROSITE
PS50103, ZF_C3H1, 3 hits

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZC3HA_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96K80
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: December 1, 2001
Last modified: June 2, 2021
This is version 142 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
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