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Entry version 123 (18 Sep 2019)
Sequence version 1 (01 Dec 2001)
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Protein

RBPJ-interacting and tubulin-associated protein 1

Gene

RITA1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processNeurogenesis, Notch signaling pathway

Enzyme and pathway databases

SIGNOR Signaling Network Open Resource

More...
SIGNORi
Q96K30

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
RBPJ-interacting and tubulin-associated protein 1
Alternative name(s):
RBPJ-interacting and tubulin-associated protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RITA1
Synonyms:C12orf52, RITA
ORF Names:PSEC0043
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:25925 RITA1

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q96K30

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi7L → A: Results in nuclear accumulation; when associated with A-12 and A-15. 1 Publication1
Mutagenesisi12M → A: Results in nuclear accumulation; when associated with A-7 and A-15. 1 Publication1
Mutagenesisi15L → A: Results in nuclear accumulation; when associated with A-7 and A-12. 1 Publication1
Mutagenesisi95 – 97RKK → AAA: Abolishes nuclear localization. 1 Publication3

Organism-specific databases

DisGeNET

More...
DisGeNETi
84934

Open Targets

More...
OpenTargetsi
ENSG00000139405

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA143485381

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
RITA1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002944291 – 269RBPJ-interacting and tubulin-associated protein 1Add BLAST269

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q96K30

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q96K30

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q96K30

PeptideAtlas

More...
PeptideAtlasi
Q96K30

PRoteomics IDEntifications database

More...
PRIDEi
Q96K30

ProteomicsDB human proteome resource

More...
ProteomicsDBi
28435
77035 [Q96K30-1]
77036 [Q96K30-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q96K30

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q96K30

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000139405 Expressed in 192 organ(s), highest expression level in muscle of leg

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q96K30 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q96K30 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA039094
HPA039095
HPA061531

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with RBPJ/RBPSUH.

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
124368, 5 interactors

Protein interaction database and analysis system

More...
IntActi
Q96K30, 10 interactors

Molecular INTeraction database

More...
MINTi
Q96K30

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000448680

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1269
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q96K30

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni128 – 156Interaction with RBPJ/RBPSUH1 PublicationAdd BLAST29
Regioni156 – 269Interaction with tubulinAdd BLAST114

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi5 – 17Nuclear export signalAdd BLAST13
Motifi92 – 108Nuclear localization signalAdd BLAST17

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the RITA family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IKKU Eukaryota
ENOG411251C LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000013005

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000111762

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q96K30

Identification of Orthologs from Complete Genome Data

More...
OMAi
KPKPPWK

Database of Orthologous Groups

More...
OrthoDBi
1387213at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q96K30

TreeFam database of animal gene trees

More...
TreeFami
TF337291

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR031418 RITA1

The PANTHER Classification System

More...
PANTHERi
PTHR34917 PTHR34917, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF17066 RITA, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q96K30-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MKTPVELAVS GMQTLGLQHR CRGGYRVKAR TSYVDETLFG SPAGTRPTPP
60 70 80 90 100
DFDPPWVEKA NRTRGVGKEA SKALGAKGSC ETTPSRGSTP TLTPRKKNKY
110 120 130 140 150
RPISHTPSYC DESLFGSRSE GASFGAPRMA KGDAAKLRAL LWTPPPTPRG
160 170 180 190 200
SHSPRPREAP LRAIHPAGPS KTEPGPAADS QKLSMGGLHS SRPLKRGLSH
210 220 230 240 250
SLTHLNVPST GHPATSAPHT NGPQDLRPST SGVTFRSPLV TSRARSVSIS
260
VPSTPRRGGA TQKPKPPWK
Length:269
Mass (Da):28,619
Last modified:December 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3F053E1454F60773
GO
Isoform 2 (identifier: Q96K30-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     161-177: LRAIHPAGPSKTEPGPA → VPPTQMGLRISGLPRQG
     178-269: Missing.

Note: No experimental confirmation available.
Show »
Length:177
Mass (Da):19,050
Checksum:i834FD0C7095AED0B
GO
Isoform 3 (identifier: Q96K30-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MLREPRKQGLAGRAHLLSPGTTGSM

Note: No experimental confirmation available. Gene prediction based on partial EST data.
Show »
Length:293
Mass (Da):31,135
Checksum:i0CCC65D03B9B6825
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A087X1G3A0A087X1G3_HUMAN
RBPJ-interacting and tubulin-associ...
RITA1
38Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti73A → S in BAG53956 (PubMed:14702039).Curated1
Sequence conflicti217A → V in BAD96628 (Ref. 2) Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_050865113S → W. Corresponds to variant dbSNP:rs16942601Ensembl.1
Natural variantiVAR_033175220T → K. Corresponds to variant dbSNP:rs34831139Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0556491M → MLREPRKQGLAGRAHLLSPG TTGSM in isoform 3. Curated1
Alternative sequenceiVSP_026636161 – 177LRAIH…EPGPA → VPPTQMGLRISGLPRQG in isoform 2. 1 PublicationAdd BLAST17
Alternative sequenceiVSP_026637178 – 269Missing in isoform 2. 1 PublicationAdd BLAST92

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK075358 mRNA Translation: BAC11568.1
AK027733 mRNA Translation: BAB55328.1
AK027741 mRNA Translation: BAB55333.1
AK123762 mRNA Translation: BAG53956.1
AK222908 mRNA Translation: BAD96628.1
AC089999 Genomic DNA No translation available.
BC022092 mRNA Translation: AAH22092.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS66473.1 [Q96K30-3]
CCDS9166.1 [Q96K30-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001273144.1, NM_001286215.1 [Q96K30-3]
NP_116237.1, NM_032848.2 [Q96K30-1]
XP_005254029.1, XM_005253972.2 [Q96K30-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000548278; ENSP00000449841; ENSG00000139405 [Q96K30-1]
ENST00000549621; ENSP00000448289; ENSG00000139405 [Q96K30-1]
ENST00000552495; ENSP00000448680; ENSG00000139405 [Q96K30-3]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
84934

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:84934

UCSC genome browser

More...
UCSCi
uc001tur.2 human [Q96K30-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK075358 mRNA Translation: BAC11568.1
AK027733 mRNA Translation: BAB55328.1
AK027741 mRNA Translation: BAB55333.1
AK123762 mRNA Translation: BAG53956.1
AK222908 mRNA Translation: BAD96628.1
AC089999 Genomic DNA No translation available.
BC022092 mRNA Translation: AAH22092.1
CCDSiCCDS66473.1 [Q96K30-3]
CCDS9166.1 [Q96K30-1]
RefSeqiNP_001273144.1, NM_001286215.1 [Q96K30-3]
NP_116237.1, NM_032848.2 [Q96K30-1]
XP_005254029.1, XM_005253972.2 [Q96K30-1]

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5EG6X-ray2.09R133-148[»]
SMRiQ96K30
ModBaseiSearch...

Protein-protein interaction databases

BioGridi124368, 5 interactors
IntActiQ96K30, 10 interactors
MINTiQ96K30
STRINGi9606.ENSP00000448680

PTM databases

iPTMnetiQ96K30
PhosphoSitePlusiQ96K30

Polymorphism and mutation databases

BioMutaiRITA1

Proteomic databases

jPOSTiQ96K30
MassIVEiQ96K30
PaxDbiQ96K30
PeptideAtlasiQ96K30
PRIDEiQ96K30
ProteomicsDBi28435
77035 [Q96K30-1]
77036 [Q96K30-2]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
84934
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000548278; ENSP00000449841; ENSG00000139405 [Q96K30-1]
ENST00000549621; ENSP00000448289; ENSG00000139405 [Q96K30-1]
ENST00000552495; ENSP00000448680; ENSG00000139405 [Q96K30-3]
GeneIDi84934
KEGGihsa:84934
UCSCiuc001tur.2 human [Q96K30-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
84934
DisGeNETi84934

GeneCards: human genes, protein and diseases

More...
GeneCardsi
RITA1
HGNCiHGNC:25925 RITA1
HPAiHPA039094
HPA039095
HPA061531
neXtProtiNX_Q96K30
OpenTargetsiENSG00000139405
PharmGKBiPA143485381

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IKKU Eukaryota
ENOG411251C LUCA
GeneTreeiENSGT00390000013005
HOGENOMiHOG000111762
InParanoidiQ96K30
OMAiKPKPPWK
OrthoDBi1387213at2759
PhylomeDBiQ96K30
TreeFamiTF337291

Enzyme and pathway databases

SIGNORiQ96K30

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
84934

Pharos

More...
Pharosi
Q96K30

Protein Ontology

More...
PROi
PR:Q96K30

Gene expression databases

BgeeiENSG00000139405 Expressed in 192 organ(s), highest expression level in muscle of leg
ExpressionAtlasiQ96K30 baseline and differential
GenevisibleiQ96K30 HS

Family and domain databases

InterProiView protein in InterPro
IPR031418 RITA1
PANTHERiPTHR34917 PTHR34917, 1 hit
PfamiView protein in Pfam
PF17066 RITA, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRITA1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96K30
Secondary accession number(s): B3KVZ4
, C9JIN1, F8VRG5, Q53GM3, Q96K25
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: December 1, 2001
Last modified: September 18, 2019
This is version 123 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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