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Protein

Solute carrier family 41 member 2

Gene

SLC41A2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Acts as a plasma-membrane magnesium transporter.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processIon transport, Transport
LigandMagnesium

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-425410 Metal ion SLC transporters

Protein family/group databases

Transport Classification Database

More...
TCDBi
1.A.26.2.2 the mg(2+) transporter-e (mgte) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Solute carrier family 41 member 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SLC41A2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000136052.9

Human Gene Nomenclature Database

More...
HGNCi
HGNC:31045 SLC41A2

Online Mendelian Inheritance in Man (OMIM)

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MIMi
610802 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q96JW4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 162Extracellular1 PublicationAdd BLAST162
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei163 – 183HelicalSequence analysisAdd BLAST21
Topological domaini184 – 195Cytoplasmic1 PublicationAdd BLAST12
Transmembranei196 – 216HelicalSequence analysisAdd BLAST21
Topological domaini217 – 245Extracellular1 PublicationAdd BLAST29
Transmembranei246 – 266HelicalSequence analysisAdd BLAST21
Topological domaini267 – 282Cytoplasmic1 PublicationAdd BLAST16
Transmembranei283 – 303HelicalSequence analysisAdd BLAST21
Topological domaini304 – 313Extracellular1 Publication10
Transmembranei314 – 334HelicalSequence analysisAdd BLAST21
Topological domaini335 – 347Cytoplasmic1 PublicationAdd BLAST13
Transmembranei348 – 368HelicalSequence analysisAdd BLAST21
Topological domaini369 – 376Extracellular1 Publication8
Transmembranei377 – 397HelicalSequence analysisAdd BLAST21
Topological domaini398 – 406Cytoplasmic1 Publication9
Transmembranei407 – 427HelicalSequence analysisAdd BLAST21
Topological domaini428 – 469Extracellular1 PublicationAdd BLAST42
Transmembranei470 – 490HelicalSequence analysisAdd BLAST21
Topological domaini491 – 498Cytoplasmic1 Publication8
Transmembranei499 – 519HelicalSequence analysisAdd BLAST21
Topological domaini520 – 543Extracellular1 PublicationAdd BLAST24
Transmembranei544 – 564HelicalSequence analysisAdd BLAST21
Topological domaini565 – 573Cytoplasmic1 Publication9

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
84102

Open Targets

More...
OpenTargetsi
ENSG00000136052

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134931432

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
SLC41A2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
152112286

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002950401 – 573Solute carrier family 41 member 2Add BLAST573

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei136PhosphoserineBy similarity1
Modified residuei137PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
Q96JW4

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
Q96JW4

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q96JW4

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q96JW4

PeptideAtlas

More...
PeptideAtlasi
Q96JW4

PRoteomics IDEntifications database

More...
PRIDEi
Q96JW4

ProteomicsDB human proteome resource

More...
ProteomicsDBi
77010

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q96JW4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q96JW4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSG00000136052 Expressed in 174 organ(s), highest expression level in stomach

CleanEx database of gene expression profiles

More...
CleanExi
HS_SLC41A2

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q96JW4 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q96JW4 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA038658

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
CCDC155Q8N6L05EBI-10290130,EBI-749265

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
123891, 3 interactors

Protein interaction database and analysis system

More...
IntActi
Q96JW4, 28 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000258538

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q96JW4

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SLC41A transporter family.Curated

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3788 Eukaryota
ENOG410XSTG LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153803

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000007017

The HOVERGEN Database of Homologous Vertebrate Genes

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HOVERGENi
HBG057187

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q96JW4

KEGG Orthology (KO)

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KOi
K15122

Identification of Orthologs from Complete Genome Data

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OMAi
KGRSITN

Database of Orthologous Groups

More...
OrthoDBi
1059294at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q96JW4

TreeFam database of animal gene trees

More...
TreeFami
TF313647

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006667 SLC41_membr_dom
IPR036739 SLC41_membr_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01769 MgtE, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF161093 SSF161093, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All

Q96JW4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTNSKGRSIT DKTSGGPSSG GGFVDWTLRL NTIQSDKFLN LLLSMVPVIY
60 70 80 90 100
QKNQEDRHKK ANGIWQDGLS TAVQTFSNRS EQHMEYHSFS EQSFHANNGH
110 120 130 140 150
ASSSCSQKYD DYANYNYCDG RETSETTAML QDEDISSDGD EDAIVEVTPK
160 170 180 190 200
LPKESSGIMA LQILVPFLLA GFGTVSAGMV LDIVQHWEVF RKVTEVFILV
210 220 230 240 250
PALLGLKGNL EMTLASRLST AVNIGKMDSP IEKWNLIIGN LALKQVQATV
260 270 280 290 300
VGFLAAVAAI ILGWIPEGKY YLDHSILLCS SSVATAFIAS LLQGIIMVGV
310 320 330 340 350
IVGSKKTGIN PDNVATPIAA SFGDLITLAI LAWISQGLYS CLETYYYISP
360 370 380 390 400
LVGVFFLALT PIWIIIAAKH PATRTVLHSG WEPVITAMVI SSIGGLILDT
410 420 430 440 450
TVSDPNLVGI VVYTPVINGI GGNLVAIQAS RISTYLHLHS IPGELPDEPK
460 470 480 490 500
GCYYPFRTFF GPGVNNKSAQ VLLLLVIPGH LIFLYTIHLM KSGHTSLTII
510 520 530 540 550
FIVVYLFGAV LQVFTLLWIA DWMVHHFWRK GKDPDSFSIP YLTALGDLLG
560 570
TALLALSFHF LWLIGDRDGD VGD
Length:573
Mass (Da):62,473
Last modified:July 10, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1BD0FF32AF91DA02
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H7BZT9H7BZT9_HUMAN
Solute carrier family 41 member 2
SLC41A2
149Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JCR2C9JCR2_HUMAN
Solute carrier family 41 member 2
SLC41A2
143Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JYJ7C9JYJ7_HUMAN
Solute carrier family 41 member 2
SLC41A2
122Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JKF2C9JKF2_HUMAN
Solute carrier family 41 member 2
SLC41A2
94Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JDQ2C9JDQ2_HUMAN
Solute carrier family 41 member 2
SLC41A2
46Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JIL4C9JIL4_HUMAN
Solute carrier family 41 member 2
SLC41A2
76Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JA64C9JA64_HUMAN
Solute carrier family 41 member 2
SLC41A2
72Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9J2P6C9J2P6_HUMAN
Solute carrier family 41 member 2
SLC41A2
12Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH36734 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAI06872 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAI06873 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAB55402 differs from that shown. Reason: Frameshift at positions 69, 101 and 103.Curated
The sequence CAB66762 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti115Y → C in BAB55402 (PubMed:14702039).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK027838 mRNA Translation: BAB55402.1 Frameshift.
BC036734 mRNA Translation: AAH36734.1 Different initiation.
BC106871 mRNA Translation: AAI06872.2 Different initiation.
BC106872 mRNA Translation: AAI06873.2 Different initiation.
AL136828 mRNA Translation: CAB66762.1 Different initiation.

The Consensus CDS (CCDS) project

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CCDSi
CCDS9100.2

NCBI Reference Sequences

More...
RefSeqi
NP_115524.3, NM_032148.3
XP_005269233.1, XM_005269176.1
XP_005269235.1, XM_005269178.1
XP_005269236.1, XM_005269179.1
XP_006719693.1, XM_006719630.2
XP_011537109.1, XM_011538807.2
XP_011537110.1, XM_011538808.1
XP_011537111.1, XM_011538809.1
XP_011537112.1, XM_011538810.2
XP_011537113.1, XM_011538811.2
XP_016875502.1, XM_017020013.1

UniGene gene-oriented nucleotide sequence clusters

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UniGenei
Hs.577463

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000258538; ENSP00000258538; ENSG00000136052

Database of genes from NCBI RefSeq genomes

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GeneIDi
84102

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:84102

UCSC genome browser

More...
UCSCi
uc001tla.4 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK027838 mRNA Translation: BAB55402.1 Frameshift.
BC036734 mRNA Translation: AAH36734.1 Different initiation.
BC106871 mRNA Translation: AAI06872.2 Different initiation.
BC106872 mRNA Translation: AAI06873.2 Different initiation.
AL136828 mRNA Translation: CAB66762.1 Different initiation.
CCDSiCCDS9100.2
RefSeqiNP_115524.3, NM_032148.3
XP_005269233.1, XM_005269176.1
XP_005269235.1, XM_005269178.1
XP_005269236.1, XM_005269179.1
XP_006719693.1, XM_006719630.2
XP_011537109.1, XM_011538807.2
XP_011537110.1, XM_011538808.1
XP_011537111.1, XM_011538809.1
XP_011537112.1, XM_011538810.2
XP_011537113.1, XM_011538811.2
XP_016875502.1, XM_017020013.1
UniGeneiHs.577463

3D structure databases

ProteinModelPortaliQ96JW4
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi123891, 3 interactors
IntActiQ96JW4, 28 interactors
STRINGi9606.ENSP00000258538

Protein family/group databases

TCDBi1.A.26.2.2 the mg(2+) transporter-e (mgte) family

PTM databases

iPTMnetiQ96JW4
PhosphoSitePlusiQ96JW4

Polymorphism and mutation databases

BioMutaiSLC41A2
DMDMi152112286

Proteomic databases

EPDiQ96JW4
jPOSTiQ96JW4
MaxQBiQ96JW4
PaxDbiQ96JW4
PeptideAtlasiQ96JW4
PRIDEiQ96JW4
ProteomicsDBi77010

Protocols and materials databases

The DNASU plasmid repository

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DNASUi
84102
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000258538; ENSP00000258538; ENSG00000136052
GeneIDi84102
KEGGihsa:84102
UCSCiuc001tla.4 human

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
84102
DisGeNETi84102
EuPathDBiHostDB:ENSG00000136052.9

GeneCards: human genes, protein and diseases

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GeneCardsi
SLC41A2
HGNCiHGNC:31045 SLC41A2
HPAiHPA038658
MIMi610802 gene
neXtProtiNX_Q96JW4
OpenTargetsiENSG00000136052
PharmGKBiPA134931432

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG3788 Eukaryota
ENOG410XSTG LUCA
GeneTreeiENSGT00940000153803
HOGENOMiHOG000007017
HOVERGENiHBG057187
InParanoidiQ96JW4
KOiK15122
OMAiKGRSITN
OrthoDBi1059294at2759
PhylomeDBiQ96JW4
TreeFamiTF313647

Enzyme and pathway databases

ReactomeiR-HSA-425410 Metal ion SLC transporters

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
SLC41A2 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
84102

Protein Ontology

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PROi
PR:Q96JW4

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000136052 Expressed in 174 organ(s), highest expression level in stomach
CleanExiHS_SLC41A2
ExpressionAtlasiQ96JW4 baseline and differential
GenevisibleiQ96JW4 HS

Family and domain databases

InterProiView protein in InterPro
IPR006667 SLC41_membr_dom
IPR036739 SLC41_membr_dom_sf
PfamiView protein in Pfam
PF01769 MgtE, 2 hits
SUPFAMiSSF161093 SSF161093, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiS41A2_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96JW4
Secondary accession number(s): Q3KP68, Q9H0E5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: July 10, 2007
Last modified: January 16, 2019
This is version 133 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Human chromosome 12
    Human chromosome 12: entries, gene names and cross-references to MIM
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