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Entry version 156 (16 Oct 2019)
Sequence version 3 (28 Feb 2003)
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Protein

Zinc finger protein 333

Gene

ZNF333

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri366 – 388C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri394 – 416C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri422 – 444C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri450 – 472C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri478 – 500C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri506 – 528C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri534 – 556C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri562 – 584C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri590 – 612C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri618 – 640C2H2-type 10PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-212436 Generic Transcription Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 333
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF333
Synonyms:KIAA1806
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:15624 ZNF333

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
611811 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q96JL9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000160961

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134929553

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q96JL9

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF333

Domain mapping of disease mutations (DMDM)

More...
DMDMi
29840870

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000475361 – 665Zinc finger protein 333Add BLAST665

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q96JL9

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q96JL9

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q96JL9

PeptideAtlas

More...
PeptideAtlasi
Q96JL9

PRoteomics IDEntifications database

More...
PRIDEi
Q96JL9

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
66895
76980 [Q96JL9-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q96JL9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q96JL9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highly expressed in heart.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000160961 Expressed in 148 organ(s), highest expression level in myometrium

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
Q96JL9 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q96JL9 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA043973
HPA054680

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
124087, 9 interactors

Protein interaction database and analysis system

More...
IntActi
Q96JL9, 4 interactors

Molecular INTeraction database

More...
MINTi
Q96JL9

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000292530

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q96JL9

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini4 – 74KRAB 1PROSITE-ProRule annotationAdd BLAST71
Domaini203 – 274KRAB 2PROSITE-ProRule annotationAdd BLAST72

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri366 – 388C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri394 – 416C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri422 – 444C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri450 – 472C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri478 – 500C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri506 – 528C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri534 – 556C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri562 – 584C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri590 – 612C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri618 – 640C2H2-type 10PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721 Eukaryota
COG5048 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000163161

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000234617

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q96JL9

KEGG Orthology (KO)

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KOi
K09228

Identification of Orthologs from Complete Genome Data

More...
OMAi
THTTEKC

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q96JL9

TreeFam database of animal gene trees

More...
TreeFami
TF350814

Family and domain databases

Conserved Domains Database

More...
CDDi
cd07765 KRAB_A-box, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR003656 Znf_BED
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01352 KRAB, 2 hits
PF00096 zf-C2H2, 8 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00349 KRAB, 2 hits
SM00614 ZnF_BED, 2 hits
SM00355 ZnF_C2H2, 10 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF109640 SSF109640, 2 hits
SSF57667 SSF57667, 7 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50805 KRAB, 2 hits
PS00028 ZINC_FINGER_C2H2_1, 10 hits
PS50157 ZINC_FINGER_C2H2_2, 10 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q96JL9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MESVTFEDVA VEFIQEWALL DSARRSLCKY RMLDQCRTLA SRGTPPCKPS
60 70 80 90 100
CVSQLGQRAE PKATERGILR ATGVAWESQL KPEELPSMQD LLEEASSRDM
110 120 130 140 150
QMGPGLFLRM QLVPSIEERE TPLTREDRPA LQEPPWSLGC TGLKAAMQIQ
160 170 180 190 200
RVVIPVPTLG HRNPWVARDS AVPARDPAWL QEDKVEEEAM APGLPTACSQ
210 220 230 240 250
EPVTFADVAV VFTPEEWVFL DSTQRSLYRD VMLENYRNLA SVADQLCKPN
260 270 280 290 300
ALSYLEERGE QWTTDRGVLS DTCAEPQCQP QEAIPSQDTF TEILSIDVKG
310 320 330 340 350
EQPQPGEKLY KYNELEKPFN SIEPLFQYQR IHAGEASCEC QEIRNSFFQS
360 370 380 390 400
AHLIVPEKIR SGDKSYACNK CEKSFRYSSD LIRHEKTHTA EKCFDCQECG
410 420 430 440 450
QAFKYSSNLR RHMRTHTGEK PFECSQCGKT FTRNFNLILH QRNHTGEKPY
460 470 480 490 500
ECKDCGKAFN QPSSLRSHVR THTGEKPFEC SQCGKAFREH SSLKTHLRTH
510 520 530 540 550
TREKPYECNQ CGKPFRTSTH LNVHKRIHTG EKLYECATCG QVLSRLSTLK
560 570 580 590 600
SHMRTHTGEK PYVCQECGRA FSEPSSLRKH ARTHSGKKPY ACQECGRAFG
610 620 630 640 650
QSSHLIVHVR THSAGRPYQC NQCEKAFRHS SSLTVHKRTH VGRETIRNGS
660
LPLSMSHPYC GPLAN
Length:665
Mass (Da):75,544
Last modified:February 28, 2003 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEE5ABF8468D8DD24
GO
Isoform 2 (identifier: Q96JL9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     142-182: GLKAAMQIQR...PARDPAWLQE → LPLLSLLLPS...TLDTEARGIP
     183-665: Missing.

Show »
Length:182
Mass (Da):20,198
Checksum:i59AB52A753D4954E
GO
Isoform 3 (identifier: Q96JL9-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     301-302: EQ → PPN
     303-665: Missing.

Note: No experimental confirmation available.
Show »
Length:303
Mass (Da):33,917
Checksum:i0948D4793CC59D4C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M0R1P1M0R1P1_HUMAN
Zinc finger protein 333
ZNF333
166Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0R0S8M0R0S8_HUMAN
Zinc finger protein 333
ZNF333
195Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0R113M0R113_HUMAN
Zinc finger protein 333
ZNF333
106Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti115S → P in AAH48107 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_024210251A → E. Corresponds to variant dbSNP:rs3885179Ensembl.1
Natural variantiVAR_052812537A → V. Corresponds to variant dbSNP:rs3764626Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_055945142 – 182GLKAA…AWLQE → LPLLSLLLPSCPEPPLVLLD SSSAPDRHLGSTLDTEARGI P in isoform 2. 2 PublicationsAdd BLAST41
Alternative sequenceiVSP_055946183 – 665Missing in isoform 2. 2 PublicationsAdd BLAST483
Alternative sequenceiVSP_055947301 – 302EQ → PPN in isoform 3. 1 Publication2
Alternative sequenceiVSP_055948303 – 665Missing in isoform 3. 1 PublicationAdd BLAST363

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF372702 mRNA Translation: AAM15528.1
AK291471 mRNA Translation: BAF84160.1
BC048107 mRNA Translation: AAH48107.1
BC064571 mRNA Translation: AAH64571.1
AB058709 mRNA Translation: BAB47435.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS12316.1 [Q96JL9-1]
CCDS74298.1 [Q96JL9-3]

NCBI Reference Sequences

More...
RefSeqi
NP_001287841.1, NM_001300912.1 [Q96JL9-3]
NP_115809.1, NM_032433.2 [Q96JL9-1]
XP_011526664.1, XM_011528362.2 [Q96JL9-1]
XP_016882856.1, XM_017027367.1 [Q96JL9-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000292530; ENSP00000292530; ENSG00000160961 [Q96JL9-1]
ENST00000540689; ENSP00000438130; ENSG00000160961 [Q96JL9-3]

Database of genes from NCBI RefSeq genomes

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GeneIDi
84449

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
hsa:84449

UCSC genome browser

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UCSCi
uc002mzn.4 human [Q96JL9-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF372702 mRNA Translation: AAM15528.1
AK291471 mRNA Translation: BAF84160.1
BC048107 mRNA Translation: AAH48107.1
BC064571 mRNA Translation: AAH64571.1
AB058709 mRNA Translation: BAB47435.1
CCDSiCCDS12316.1 [Q96JL9-1]
CCDS74298.1 [Q96JL9-3]
RefSeqiNP_001287841.1, NM_001300912.1 [Q96JL9-3]
NP_115809.1, NM_032433.2 [Q96JL9-1]
XP_011526664.1, XM_011528362.2 [Q96JL9-1]
XP_016882856.1, XM_017027367.1 [Q96JL9-1]

3D structure databases

SMRiQ96JL9
ModBaseiSearch...

Protein-protein interaction databases

BioGridi124087, 9 interactors
IntActiQ96JL9, 4 interactors
MINTiQ96JL9
STRINGi9606.ENSP00000292530

PTM databases

iPTMnetiQ96JL9
PhosphoSitePlusiQ96JL9

Polymorphism and mutation databases

BioMutaiZNF333
DMDMi29840870

Proteomic databases

jPOSTiQ96JL9
MassIVEiQ96JL9
PaxDbiQ96JL9
PeptideAtlasiQ96JL9
PRIDEiQ96JL9
ProteomicsDBi66895
76980 [Q96JL9-1]

Protocols and materials databases

The DNASU plasmid repository

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DNASUi
84449

Genome annotation databases

EnsembliENST00000292530; ENSP00000292530; ENSG00000160961 [Q96JL9-1]
ENST00000540689; ENSP00000438130; ENSG00000160961 [Q96JL9-3]
GeneIDi84449
KEGGihsa:84449
UCSCiuc002mzn.4 human [Q96JL9-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
84449

GeneCards: human genes, protein and diseases

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GeneCardsi
ZNF333
HGNCiHGNC:15624 ZNF333
HPAiHPA043973
HPA054680
MIMi611811 gene
neXtProtiNX_Q96JL9
OpenTargetsiENSG00000160961
PharmGKBiPA134929553

Human Unidentified Gene-Encoded large proteins database

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HUGEi
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GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00940000163161
HOGENOMiHOG000234617
InParanoidiQ96JL9
KOiK09228
OMAiTHTTEKC
OrthoDBi1318335at2759
PhylomeDBiQ96JL9
TreeFamiTF350814

Enzyme and pathway databases

ReactomeiR-HSA-212436 Generic Transcription Pathway

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
ZNF333 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
84449
PharosiQ96JL9

Protein Ontology

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PROi
PR:Q96JL9

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000160961 Expressed in 148 organ(s), highest expression level in myometrium
ExpressionAtlasiQ96JL9 baseline and differential
GenevisibleiQ96JL9 HS

Family and domain databases

CDDicd07765 KRAB_A-box, 2 hits
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR003656 Znf_BED
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF01352 KRAB, 2 hits
PF00096 zf-C2H2, 8 hits
SMARTiView protein in SMART
SM00349 KRAB, 2 hits
SM00614 ZnF_BED, 2 hits
SM00355 ZnF_C2H2, 10 hits
SUPFAMiSSF109640 SSF109640, 2 hits
SSF57667 SSF57667, 7 hits
PROSITEiView protein in PROSITE
PS50805 KRAB, 2 hits
PS00028 ZINC_FINGER_C2H2_1, 10 hits
PS50157 ZINC_FINGER_C2H2_2, 10 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN333_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96JL9
Secondary accession number(s): Q6P2E6, Q86WS6, Q8TDL0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 21, 2002
Last sequence update: February 28, 2003
Last modified: October 16, 2019
This is version 156 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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