HIC2

Functionⁱ

Transcriptional repressor.

Regions

Feature key	Position(s)	DescriptionActions	Length
Zinc fingerⁱ	442 – 469	C2H2-type 1PROSITE-ProRule annotationAdd BLAST	28
Zinc fingerⁱ	505 – 532	C2H2-type 2PROSITE-ProRule annotationAdd BLAST	28
Zinc fingerⁱ	533 – 560	C2H2-type 3PROSITE-ProRule annotationAdd BLAST	28
Zinc fingerⁱ	561 – 588	C2H2-type 4PROSITE-ProRule annotationAdd BLAST	28
Zinc fingerⁱ	589 – 615	C2H2-type 5PROSITE-ProRule annotationAdd BLAST	27

GO - Molecular functionⁱ

DNA binding
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
DNA-binding transcription factor activity, RNA polymerase II-specific Source: NTNU_SB
DNA-binding transcription repressor activity, RNA polymerase II-specific
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
metal ion binding Source: UniProtKB-KW
protein C-terminus binding
Source: UniProtKB
Inferred from physical interactionⁱ
- 12052894
RNA polymerase II regulatory region sequence-specific DNA binding
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

negative regulation of transcription, DNA-templated
Source: UniProtKB
Non-traceable author statementⁱ
- 11554746

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	DNA-binding, Repressor
Biological process	Transcription, Transcription regulation
Ligand	Metal-binding, Zinc

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Hypermethylated in cancer 2 protein Short name: Hic-2 Alternative name(s): HIC1-related gene on chromosome 22 protein Hic-3 Zinc finger and BTB domain-containing protein 30
Gene namesⁱ	Name:HIC2 Synonyms:HRG22, KIAA1020, ZBTB30
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 22

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000169635.9
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:18595 HIC2
MIMⁱ	607712 gene
neXtProtⁱ	NX_Q96JB3

Keywords - Cellular componentⁱ

Nucleus

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	23119
Open Targets More...OpenTargetsⁱ	ENSG00000169635
PharmGKBⁱ	PA38357

Polymorphism and mutation databases

BioMutaⁱ	HIC2
DMDMⁱ	20454983

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000046945	1 – 615	Hypermethylated in cancer 2 proteinAdd BLAST		615

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Modified residueⁱ	166	PhosphoserineCombined sources	1
Modified residueⁱ	169	PhosphoserineCombined sources	1
Modified residueⁱ	197	PhosphoserineCombined sources	1
Modified residueⁱ	348	PhosphoserineCombined sources	1
Modified residueⁱ	412	PhosphoserineCombined sources	1

Keywords - PTMⁱ

Phosphoprotein

Proteomic databases

EPDⁱ	Q96JB3
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q96JB3
PaxDbⁱ	Q96JB3
PeptideAtlas More...PeptideAtlasⁱ	Q96JB3
PRIDEⁱ	Q96JB3
ProteomicsDBⁱ	76928 76929 [Q96JB3-2]

PTM databases

iPTMnetⁱ	Q96JB3
PhosphoSitePlusⁱ	Q96JB3

Expressionⁱ

Tissue specificityⁱ

Highest levels in cerebellum.

Gene expression databases

Bgeeⁱ	ENSG00000169635 Expressed in 218 organ(s), highest expression level in secondary oocyte
CleanExⁱ	HS_HIC2
Genevisibleⁱ	Q96JB3 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA031884 HPA059399

HPAⁱ

HPA031884
HPA059399

Interactionⁱ

Subunit structureⁱ

Self-associates. Interacts with HIC1.1 Publication

GO - Molecular functionⁱ

protein C-terminus binding
Source: UniProtKB
Inferred from physical interactionⁱ
- 12052894

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridⁱ	116741, 20 interactors
IntActⁱ	Q96JB3, 13 interactors
Molecular INTeraction database More...MINTⁱ	Q96JB3
STRINGⁱ	9606.ENSP00000384889

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q96JB3
SMRⁱ	Q96JB3
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	46 – 109	BTBPROSITE-ProRule annotationAdd BLAST		64

Region

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Regionⁱ	246 – 250	Binding to CtBP		5

Sequence similaritiesⁱ

Belongs to the krueppel C2H2-type zinc-finger protein family. Hic subfamily.Curated

Zinc finger

Feature key	Position(s)	DescriptionActions	Length
Zinc fingerⁱ	442 – 469	C2H2-type 1PROSITE-ProRule annotationAdd BLAST	28
Zinc fingerⁱ	505 – 532	C2H2-type 2PROSITE-ProRule annotationAdd BLAST	28
Zinc fingerⁱ	533 – 560	C2H2-type 3PROSITE-ProRule annotationAdd BLAST	28
Zinc fingerⁱ	561 – 588	C2H2-type 4PROSITE-ProRule annotationAdd BLAST	28
Zinc fingerⁱ	589 – 615	C2H2-type 5PROSITE-ProRule annotationAdd BLAST	27

Keywords - Domainⁱ

Repeat, Zinc-finger

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00930000150995
HOGENOMⁱ	HOG000026793
HOVERGENⁱ	HBG079492
InParanoidⁱ	Q96JB3
OMAⁱ	EGAEDNH
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G054Q
PhylomeDBⁱ	Q96JB3
TreeFamⁱ	TF333488

Family and domain databases

InterProⁱ	View protein in InterPro IPR000210 BTB/POZ_dom IPR011333 SKP1/BTB/POZ_sf IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00651 BTB, 1 hit PF00096 zf-C2H2, 3 hits
SMARTⁱ	View protein in SMART SM00225 BTB, 1 hit SM00355 ZnF_C2H2, 5 hits
SUPFAMⁱ	SSF54695 SSF54695, 1 hit SSF57667 SSF57667, 3 hits
PROSITEⁱ	View protein in PROSITE PS50097 BTB, 1 hit PS00028 ZINC_FINGER_C2H2_1, 5 hits PS50157 ZINC_FINGER_C2H2_2, 5 hits

Sequences (2)ⁱ

Sequence statusⁱ: Complete.

This entry describes 2 isoformsⁱ produced by alternative splicing. Align Add to basket

Isoform 1 (identifier: Q96JB3-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MVSGPLALRW CAWAGRGDMG PDMELPSHSK QLLLQLNQQR TKGFLCDVII 
        60         70         80         90        100
MVENSIFRAH KNVLAASSIY FKSLVLHDNL INLDTDMVSS TVFQQILDFI 
       110        120        130        140        150
YTGKLLPSDQ PAEPNFSTLL TAASYLQLPE LAALCRRKLK RAGKPFGSGR 
       160        170        180        190        200
AGSTGMGRPP RSQRLSTASV IQARYQGLVD GRKGAHAPQE LPQAKGSDDE 
       210        220        230        240        250
LFLGGSNQDS VQGLGRAVCP AGGEAGLGGC SSSTNGSSGG CEQELGLDLS 
       260        270        280        290        300
KKSPPLPPAT PGPHLTPDDA AQLSDSQHGS PPAASAPPVA NSASYSELGG 
       310        320        330        340        350
TPDEPMDLEG AEDNHLSLLE APGGQPRKSL RHSTRKKEWG KKEPVAGSPF 
       360        370        380        390        400
ERREAGPKGP CPGEEGEGVG DRVPNGILAS GAGPSGPYGE PPYPCKEEEE 
       410        420        430        440        450
NGKDASEDSA QSGSEGGSGH ASAHYMYRQE GYETVSYGDN LYVCIPCAKG 
       460        470        480        490        500
FPSSEQLNAH VETHTEEELF IKEEGAYETG SGGAEEEAED LSAPSAAYTA 
       510        520        530        540        550
EPRPFKCSVC EKTYKDPATL RQHEKTHWLT RPFPCNICGK MFTQRGTMTR 
       560        570        580        590        600
HMRSHLGLKP FACDECGMRF TRQYRLTEHM RVHSGEKPYE CQLCGGKFTQ 
       610 
QRNLISHLRM HTSPS

Length:615

Mass (Da):66,156

Last modified:May 2, 2002 - v2

Checksum:ⁱB0368C631B198C95

GO

Isoform 2 (identifier: Q96JB3-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
1-18: Missing.

« Hide

        10         20         30         40         50
MGPDMELPSH SKQLLLQLNQ QRTKGFLCDV IIMVENSIFR AHKNVLAASS 
        60         70         80         90        100
IYFKSLVLHD NLINLDTDMV SSTVFQQILD FIYTGKLLPS DQPAEPNFST 
       110        120        130        140        150
LLTAASYLQL PELAALCRRK LKRAGKPFGS GRAGSTGMGR PPRSQRLSTA 
       160        170        180        190        200
SVIQARYQGL VDGRKGAHAP QELPQAKGSD DELFLGGSNQ DSVQGLGRAV 
       210        220        230        240        250
CPAGGEAGLG GCSSSTNGSS GGCEQELGLD LSKKSPPLPP ATPGPHLTPD 
       260        270        280        290        300
DAAQLSDSQH GSPPAASAPP VANSASYSEL GGTPDEPMDL EGAEDNHLSL 
       310        320        330        340        350
LEAPGGQPRK SLRHSTRKKE WGKKEPVAGS PFERREAGPK GPCPGEEGEG 
       360        370        380        390        400
VGDRVPNGIL ASGAGPSGPY GEPPYPCKEE EENGKDASED SAQSGSEGGS 
       410        420        430        440        450
GHASAHYMYR QEGYETVSYG DNLYVCIPCA KGFPSSEQLN AHVETHTEEE 
       460        470        480        490        500
LFIKEEGAYE TGSGGAEEEA EDLSAPSAAY TAEPRPFKCS VCEKTYKDPA 
       510        520        530        540        550
TLRQHEKTHW LTRPFPCNIC GKMFTQRGTM TRHMRSHLGL KPFACDECGM 
       560        570        580        590 
RFTRQYRLTE HMRVHSGEKP YECQLCGGKF TQQRNLISHL RMHTSPS

Show »

Length:597

Mass (Da):64,228

Checksum:ⁱC536567FC3A1AAC8

GO

Sequence cautionⁱ

The sequence BAA82972 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	49 – 51	IIM → TIR in CAC70715 (PubMed:11554746).Curated		3
Sequence conflictⁱ	176	Q → R in BAA82972 (PubMed:10470851).Curated		1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_006829	1 – 18	Missing in isoform 2. 1 PublicationAdd BLAST		18

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AJ313204 mRNA Translation: CAC70715.1 AF349035 mRNA Translation: AAK72951.1 AB028943 mRNA Translation: BAA82972.2 Different initiation. CR456377 mRNA Translation: CAG30263.1 AP000557 Genomic DNA No translation available. BC094787 mRNA Translation: AAH94787.1 AL162003 mRNA Translation: CAB82344.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS13789.1 [Q96JB3-1]
PIRⁱ	T47181
NCBI Reference Sequences More...RefSeqⁱ	NP_055909.2, NM_015094.2 [Q96JB3-1] XP_011528309.1, XM_011530007.2 [Q96JB3-1] XP_011528310.1, XM_011530008.2 [Q96JB3-1] XP_011528311.1, XM_011530009.2 [Q96JB3-1] XP_011528312.1, XM_011530010.2 [Q96JB3-1] XP_016884158.1, XM_017028669.1 [Q96JB3-2]
UniGeneⁱ	Hs.632767

Genome annotation databases

Ensemblⁱ	ENST00000407464; ENSP00000385319; ENSG00000169635 [Q96JB3-1] ENST00000407598; ENSP00000384889; ENSG00000169635 [Q96JB3-1] ENST00000443632; ENSP00000387757; ENSG00000169635 [Q96JB3-1]
GeneIDⁱ	23119
KEGGⁱ	hsa:23119
UCSC genome browser More...UCSCⁱ	uc002zur.5 human [Q96JB3-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q96JB3	Isoform 2 of Hypermethylated in cancer 2 protein		HUMAN		597	UniRef90_Q96JB3
HIC ZBTB transcriptional repressor 2		RABIT		667
Uncharacterized protein		CAVPO		618
Uncharacterized protein		ICTTR		618
Hypermethylated in cancer 2 protein		CASCN		618
+68

Protein	Similar proteins		Species	Score	Length	Source
Q96JB3	Hypermethylated in cancer 2 protein		MOUSE		619	UniRef50_Q96JB3
Isoform 2 of Hypermethylated in cancer 2 protein		HUMAN		597
HIC ZBTB transcriptional repressor 2		RABIT		667
Uncharacterized protein		ICTTR		618
Hypermethylated in cancer 2 protein		CASCN		618
+303

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AJ313204 mRNA Translation: CAC70715.1 AF349035 mRNA Translation: AAK72951.1 AB028943 mRNA Translation: BAA82972.2 Different initiation. CR456377 mRNA Translation: CAG30263.1 AP000557 Genomic DNA No translation available. BC094787 mRNA Translation: AAH94787.1 AL162003 mRNA Translation: CAB82344.1
CCDSⁱ	CCDS13789.1 [Q96JB3-1]
PIRⁱ	T47181
RefSeqⁱ	NP_055909.2, NM_015094.2 [Q96JB3-1] XP_011528309.1, XM_011530007.2 [Q96JB3-1] XP_011528310.1, XM_011530008.2 [Q96JB3-1] XP_011528311.1, XM_011530009.2 [Q96JB3-1] XP_011528312.1, XM_011530010.2 [Q96JB3-1] XP_016884158.1, XM_017028669.1 [Q96JB3-2]
UniGeneⁱ	Hs.632767

3D structure databases

ProteinModelPortalⁱ	Q96JB3
SMRⁱ	Q96JB3
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	116741, 20 interactors
IntActⁱ	Q96JB3, 13 interactors
MINTⁱ	Q96JB3
STRINGⁱ	9606.ENSP00000384889

PTM databases

iPTMnetⁱ	Q96JB3
PhosphoSitePlusⁱ	Q96JB3

Polymorphism and mutation databases

BioMutaⁱ	HIC2
DMDMⁱ	20454983

Proteomic databases

EPDⁱ	Q96JB3
MaxQBⁱ	Q96JB3
PaxDbⁱ	Q96JB3
PeptideAtlasⁱ	Q96JB3
PRIDEⁱ	Q96JB3
ProteomicsDBⁱ	76928 76929 [Q96JB3-2]

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	23119
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000407464; ENSP00000385319; ENSG00000169635 [Q96JB3-1] ENST00000407598; ENSP00000384889; ENSG00000169635 [Q96JB3-1] ENST00000443632; ENSP00000387757; ENSG00000169635 [Q96JB3-1]
GeneIDⁱ	23119
KEGGⁱ	hsa:23119
UCSCⁱ	uc002zur.5 human [Q96JB3-1]

Organism-specific databases

CTDⁱ	23119
DisGeNETⁱ	23119
EuPathDBⁱ	HostDB:ENSG00000169635.9
GeneCardsⁱ	HIC2
HGNCⁱ	HGNC:18595 HIC2
HPAⁱ	HPA031884 HPA059399
MIMⁱ	607712 gene
neXtProtⁱ	NX_Q96JB3
OpenTargetsⁱ	ENSG00000169635
PharmGKBⁱ	PA38357
HUGEⁱ	Search...
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
GeneTreeⁱ	ENSGT00930000150995
HOGENOMⁱ	HOG000026793
HOVERGENⁱ	HBG079492
InParanoidⁱ	Q96JB3
OMAⁱ	EGAEDNH
OrthoDBⁱ	EOG091G054Q
PhylomeDBⁱ	Q96JB3
TreeFamⁱ	TF333488

Miscellaneous databases

ChiTaRSⁱ	HIC2 human
GeneWikiⁱ	HIC2
GenomeRNAiⁱ	23119
Protein Ontology More...PROⁱ	PR:Q96JB3
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000169635 Expressed in 218 organ(s), highest expression level in secondary oocyte
CleanExⁱ	HS_HIC2
Genevisibleⁱ	Q96JB3 HS

Family and domain databases

InterProⁱ	View protein in InterPro IPR000210 BTB/POZ_dom IPR011333 SKP1/BTB/POZ_sf IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
Pfamⁱ	View protein in Pfam PF00651 BTB, 1 hit PF00096 zf-C2H2, 3 hits
SMARTⁱ	View protein in SMART SM00225 BTB, 1 hit SM00355 ZnF_C2H2, 5 hits
SUPFAMⁱ	SSF54695 SSF54695, 1 hit SSF57667 SSF57667, 3 hits
PROSITEⁱ	View protein in PROSITE PS50097 BTB, 1 hit PS00028 ZINC_FINGER_C2H2_1, 5 hits PS50157 ZINC_FINGER_C2H2_2, 5 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	HIC2_HUMAN
Accessionⁱ	Q96JB3Primary (citable) accession number: Q96JB3 Secondary accession number(s): Q504T6 , Q96KR3, Q9NSM9, Q9UPX9
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	May 2, 2002
	Last sequence update:	May 2, 2002
	Last modified:	November 7, 2018
	This is version 167 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
Human chromosome 22
Human chromosome 22: entries, gene names and cross-references to MIM

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UniProtKB - Q96JB3 (HIC2_HUMAN)

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Hypermethylated in cancer 2 protein

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Nucleus

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Region

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Keywords - Domaini

Phylogenomic databases

Family and domain databases

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Experimental Info

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Sequence cautionⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ