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Protein

Conserved oligomeric Golgi complex subunit 3

Gene

COG3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in ER-Golgi transport.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • protein transporter activity Source: UniProtKB

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processProtein transport, Transport

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-6807878 COPI-mediated anterograde transport
R-HSA-6811438 Intra-Golgi traffic
R-HSA-6811440 Retrograde transport at the Trans-Golgi-Network

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Conserved oligomeric Golgi complex subunit 3
Short name:
COG complex subunit 3
Alternative name(s):
Component of oligomeric Golgi complex 3
Vesicle-docking protein SEC34 homolog
p94
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:COG3
Synonyms:SEC34
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 13

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000136152.14

Human Gene Nomenclature Database

More...
HGNCi
HGNC:18619 COG3

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
606975 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q96JB2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Golgi apparatus, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
83548

Open Targets

More...
OpenTargetsi
ENSG00000136152

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA38602

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
COG3

Domain mapping of disease mutations (DMDM)

More...
DMDMi
85701302

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedCombined sources1 Publication
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002135002 – 828Conserved oligomeric Golgi complex subunit 3Add BLAST827

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylalanineCombined sources1 Publication1
Modified residuei663PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q96JB2

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q96JB2

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q96JB2

PeptideAtlas

More...
PeptideAtlasi
Q96JB2

PRoteomics IDEntifications database

More...
PRIDEi
Q96JB2

ProteomicsDB human proteome resource

More...
ProteomicsDBi
76926
76927 [Q96JB2-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q96JB2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q96JB2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Widely expressed with highest levels in pancreas and testis and lowest levels in lung.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000136152 Expressed in 189 organ(s), highest expression level in corpus callosum

CleanEx database of gene expression profiles

More...
CleanExi
HS_COG3

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q96JB2 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q96JB2 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA040353
HPA054470

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the conserved oligomeric Golgi complex which is composed of eight different subunits and is required for normal Golgi morphology and localization. Interacts with TMEM115.By similarity1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
123680, 60 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q96JB2

Protein interaction database and analysis system

More...
IntActi
Q96JB2, 20 interactors

Molecular INTeraction database

More...
MINTi
Q96JB2

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000258654

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q96JB2

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the COG3 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2604 Eukaryota
ENOG410XNXH LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000015682

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000264596

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG051062

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q96JB2

KEGG Orthology (KO)

More...
KOi
K20290

Identification of Orthologs from Complete Genome Data

More...
OMAi
LFEIKHL

Database of Orthologous Groups

More...
OrthoDBi
EOG091G03O0

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q96JB2

TreeFam database of animal gene trees

More...
TreeFami
TF314200

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR007265 COG_su3

The PANTHER Classification System

More...
PANTHERi
PTHR13302 PTHR13302, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04136 Sec34, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q96JB2-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAEAALLLLP EAAAERDARE KLALWDRRPD TTAPLTDRQT DSVLELKAAA
60 70 80 90 100
ENLPVPAELP IEDLCSLTSQ SLPIELTSVV PESTEDILLK GFTSLGMEEE
110 120 130 140 150
RIETAQQFFS WFAKLQTQMD QDEGTKYRQM RDYLSGFQEQ CDAILNDVNS
160 170 180 190 200
ALQHLESLQK QYLFVSNKTG TLHEACEQLL KEQSELVDLA ENIQQKLSYF
210 220 230 240 250
NELETINTKL NSPTLSVNSD GFIPMLAKLD DCITYISSHP NFKDYPIYLL
260 270 280 290 300
KFKQCLSKAL HLMKTYTVNT LQTLTSQLLK RDPSSVPNAD NAFTLFYVKF
310 320 330 340 350
RAAAPKVRTL IEQIELRSEK IPEYQQLLND IHQCYLDQRE LLLGPSIACT
360 370 380 390 400
VAELTSQNNR DHCALVRSGC AFMVHVCQDE HQLYNEFFTK PTSKLDELLE
410 420 430 440 450
KLCVSLYDVF RPLIIHVIHL ETLSELCGIL KNEVLEDHVQ NNAEQLGAFA
460 470 480 490 500
AGVKQMLEDV QERLVYRTHI YIQTDITGYK PAPGDLAYPD KLVMMEQIAQ
510 520 530 540 550
SLKDEQKKVP SEASFSDVHL EEGESNSLTK SGSTESLNPR PQTTISPADL
560 570 580 590 600
HGMWYPTVRR TLVCLSKLYR CIDRAVFQGL SQEALSACIQ SLLGASESIS
610 620 630 640 650
KNKTQIDGQL FLIKHLLILR EQIAPFHTEF TIKEISLDLK KTRDAAFKIL
660 670 680 690 700
NPMTVPRFFR LNSNNALIEF LLEGTPEIRE HYLDSKKDVD RHLKSACEQF
710 720 730 740 750
IQQQTKLFVE QLEEFMTKVS ALKTMASQGG PKYTLSQQPW AQPAKVNDLA
760 770 780 790 800
ATAYKTIKTK LPVTLRSMSL YLSNKDTEFI LFKPVRNNIQ QVFQKFHALL
810 820
KEEFSPEDIQ IIACPSMEQL SLLLLVSK
Length:828
Mass (Da):94,096
Last modified:January 23, 2007 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB3DCF03FD4DC6A60
GO
Isoform 2 (identifier: Q96JB2-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     443-444: AE → GK
     445-828: Missing.

Note: No experimental confirmation available.
Show »
Length:444
Mass (Da):50,540
Checksum:i55874C370679512F
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A087WTH9A0A087WTH9_HUMAN
Conserved oligomeric Golgi complex ...
COG3
68Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WYY9A0A087WYY9_HUMAN
Conserved oligomeric Golgi complex ...
COG3
85Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti106 – 107QQ → HE in AAK66974 (PubMed:11292827).Curated2
Sequence conflicti825L → S in AAK66974 (PubMed:11292827).Curated1
Sequence conflicti825L → S in AAK06848 (PubMed:11929878).Curated1
Sequence conflicti825L → S in BAG37012 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_036454620R → C in a breast cancer sample; somatic mutation. 1 PublicationCorresponds to variant dbSNP:rs747042102Ensembl.1
Natural variantiVAR_055663747N → S1 PublicationCorresponds to variant dbSNP:rs2274285Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_013652443 – 444AE → GK in isoform 2. 1 Publication2
Alternative sequenceiVSP_013653445 – 828Missing in isoform 2. 1 PublicationAdd BLAST384

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF349676 mRNA Translation: AAK66974.1
AF332595 mRNA Translation: AAK06848.1
AK314387 mRNA Translation: BAG37012.1
AL139326 Genomic DNA No translation available.
AL606514 Genomic DNA No translation available.
BC038953 mRNA Translation: AAH38953.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS9398.1 [Q96JB2-1]

NCBI Reference Sequences

More...
RefSeqi
NP_113619.2, NM_031431.3

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.507948

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000349995; ENSP00000258654; ENSG00000136152 [Q96JB2-1]
ENST00000617493; ENSP00000481332; ENSG00000136152 [Q96JB2-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
83548

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:83548

UCSC genome browser

More...
UCSCi
uc001vai.4 human [Q96JB2-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF349676 mRNA Translation: AAK66974.1
AF332595 mRNA Translation: AAK06848.1
AK314387 mRNA Translation: BAG37012.1
AL139326 Genomic DNA No translation available.
AL606514 Genomic DNA No translation available.
BC038953 mRNA Translation: AAH38953.1
CCDSiCCDS9398.1 [Q96JB2-1]
RefSeqiNP_113619.2, NM_031431.3
UniGeneiHs.507948

3D structure databases

ProteinModelPortaliQ96JB2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi123680, 60 interactors
CORUMiQ96JB2
IntActiQ96JB2, 20 interactors
MINTiQ96JB2
STRINGi9606.ENSP00000258654

PTM databases

iPTMnetiQ96JB2
PhosphoSitePlusiQ96JB2

Polymorphism and mutation databases

BioMutaiCOG3
DMDMi85701302

Proteomic databases

EPDiQ96JB2
MaxQBiQ96JB2
PaxDbiQ96JB2
PeptideAtlasiQ96JB2
PRIDEiQ96JB2
ProteomicsDBi76926
76927 [Q96JB2-2]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000349995; ENSP00000258654; ENSG00000136152 [Q96JB2-1]
ENST00000617493; ENSP00000481332; ENSG00000136152 [Q96JB2-2]
GeneIDi83548
KEGGihsa:83548
UCSCiuc001vai.4 human [Q96JB2-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
83548
DisGeNETi83548
EuPathDBiHostDB:ENSG00000136152.14

GeneCards: human genes, protein and diseases

More...
GeneCardsi
COG3

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0011290
HGNCiHGNC:18619 COG3
HPAiHPA040353
HPA054470
MIMi606975 gene
neXtProtiNX_Q96JB2
OpenTargetsiENSG00000136152
PharmGKBiPA38602

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG2604 Eukaryota
ENOG410XNXH LUCA
GeneTreeiENSGT00390000015682
HOGENOMiHOG000264596
HOVERGENiHBG051062
InParanoidiQ96JB2
KOiK20290
OMAiLFEIKHL
OrthoDBiEOG091G03O0
PhylomeDBiQ96JB2
TreeFamiTF314200

Enzyme and pathway databases

ReactomeiR-HSA-6807878 COPI-mediated anterograde transport
R-HSA-6811438 Intra-Golgi traffic
R-HSA-6811440 Retrograde transport at the Trans-Golgi-Network

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
COG3 human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
COG3

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
83548

Protein Ontology

More...
PROi
PR:Q96JB2

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000136152 Expressed in 189 organ(s), highest expression level in corpus callosum
CleanExiHS_COG3
ExpressionAtlasiQ96JB2 baseline and differential
GenevisibleiQ96JB2 HS

Family and domain databases

InterProiView protein in InterPro
IPR007265 COG_su3
PANTHERiPTHR13302 PTHR13302, 1 hit
PfamiView protein in Pfam
PF04136 Sec34, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCOG3_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96JB2
Secondary accession number(s): B2RAW5
, Q5VT70, Q8IXX4, Q9BZ92
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 30, 2002
Last sequence update: January 23, 2007
Last modified: November 7, 2018
This is version 141 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 13
    Human chromosome 13: entries, gene names and cross-references to MIM
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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