RNA-binding protein 41

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• pre-mRNA intronic binding Source: GO_Central
• U12 snRNA binding Source: GO_Central

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processⁱ

• developmental process Source: GO_Central
• mRNA splicing, via spliceosome Source: GO_Central

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsⁱ

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechⁱ

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingⁱ

Molecule processing

Amino acid modifications

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMⁱ

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressionⁱ

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactionⁱ

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsⁱ

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structureⁱ

Secondary structure

3D structure databases

Miscellaneous databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Domains and Repeats

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3)ⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsⁱ produced by alternative splicing. AlignAdd to basketAdded to basket

        10         20         30         40         50
MKRVNSCVKS DEHVLEELET EGERQLKSLL QHQLDTSVSI EECMSKKESF 
        60         70         80         90        100
APGTMYKPFG KEAAGTMTLS QFQTLHEKDQ ETASLRELGL NETEILIWKS 
       110        120        130        140        150
HVSGEKKTKL RATPEAIQNR LQDIEERISE RQRILCLPQR FAKSKQLTRR 
       160        170        180        190        200
EMEIEKSLFQ GADRHSFLKA LYYQDEPQKK NKGDPMNNLE SFYQEMIMKK 
       210        220        230        240        250
RLEEFQLMRG EPFASHSLVS ATSVGDSGTA ESPSLLQDKG KQAAQGKGPS 
       260        270        280        290        300
LHVANVIDFS PEQCWTGPKK LTQPIEFVPE DEIQRNRLSE EEIRKIPMFS 
       310        320        330        340        350
SYNPGEPNKV LYLKNLSPRV TERDLVSLFA RFQEKKGPPI QFRMMTGRMR 
       360        370        380        390        400
GQAFITFPNK EIAWQALHLV NGYKLHGKIL VIEFGKNKKQ RSNLQATSLI 
       410 
SCATGSTTEI SGS                                         

        10         20         30         40         50
MKRVNSCVKS DEHVLEELET EGERQLKSLL QHQLDTSVSI EECMSKKESF 
        60         70         80         90        100
APGTMYKPFG KEAAGTMTLS QFQTLHEKDQ ETASLRELGL NETEILIWKS 
       110        120        130        140        150
HVSGEKKTKL RATPEAIQNR LQDIEERISE RQRILCLPQR FAKSKQLTRR 
       160        170        180        190        200
EMEIEKSLFQ GADRHSFLKA LYYQDEPQKK NKGDPMNNLE SFYQEMIMKK 
       210        220        230        240        250
RLEEFQLMRG EPFASHSLVS ATSVGDSGTA ESPSLLQDKG KQAAQGKGPS 
       260        270        280        290        300
LHVANVIDFS PEQCWTGPKK LTQPIEFVPE DEIQRNRLSE EEIRKIPMFS 
       310        320        330        340        350
SYNPGEPNKV LYLKNLSPRV TERDLVSLFA RFQEKKGPPI QFRMMTGRMR 
       360        370        380        390        400
GQAFITFPNK EIAWQALHLV NGYKLHGKIL VIEFGKNKKQ RSNLQATSLI 

SCATG                                                  

        10         20         30         40         50
MKRVNSCVKS DEHVLEELET EGERQLKSLL QHQLDTSVSI EECMSKKESF 
        60         70         80         90        100
APGTMYKPFG KEAAGTMTLS QFQTLHEKDQ ETASLRELGL NETEILIWKS 
       110        120        130        140        150
HVSGEKKTKL RATPEAIQNR LQDIEERISE RQRILCLPQR FAKSKQLTRR 
       160        170        180        190        200
EMEIEKSLFQ GADRHSFLKA LYYQAYHKKT SADKYMTSMK RKIKLGTKDE 
       210        220        230        240        250
PQKKNKGDPM NNLESFYQEM IMKKRLEEFQ LMRGLTSFPR EDFQNLSYEG 
       260        270        280        290        300
TTSVLGAKWQ KRTGRTSTFS ILLVSLLSET VFTSSAMYGI PHLLTMSLKF 
       310 
STRIGKLSFT P                                           

Experimental Info

Natural variant

Alternative sequence

Sequence databases

Genome annotation databases

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Coding sequence diversityⁱ

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

• 100% Identity
• 90% Identity
• 50% Identity

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termⁱ

Documents

1. Human chromosome X
   Human chromosome X: entries, gene names and cross-references to MIM
2. Human entries with polymorphisms or disease mutations
   List of human entries with polymorphisms or disease mutations
3. Human polymorphisms and disease mutations
   Index of human polymorphisms and disease mutations
4. PDB cross-references
   Index of Protein Data Bank (PDB) cross-references