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UniProtKB - Q96IR2 (ZN845_HUMAN)

Entry version 155 (10 Feb 2021)
Sequence version 3 (18 May 2010)
Previous versions | rss
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Protein

Zinc finger protein 845

Gene

ZNF845

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri215 – 237C2H2-type 1; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri243 – 265C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri271 – 293C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri299 – 321C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri327 – 349C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri355 – 377C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri383 – 405C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri411 – 433C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri439 – 461C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri467 – 489C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri495 – 517C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri523 – 545C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri551 – 573C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri579 – 601C2H2-type 14PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri607 – 629C2H2-type 15PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri635 – 657C2H2-type 16PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri663 – 685C2H2-type 17PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri691 – 713C2H2-type 18PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri719 – 741C2H2-type 19PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri747 – 769C2H2-type 20PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri775 – 797C2H2-type 21PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri803 – 825C2H2-type 22PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri831 – 853C2H2-type 23PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri859 – 881C2H2-type 24PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri887 – 909C2H2-type 25PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri915 – 937C2H2-type 26PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri943 – 965C2H2-type 27PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q96IR2

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 845
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF845
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:25112, ZNF845

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q96IR2

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000213799.10

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000213799

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA162410863

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q96IR2, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		ZNF845

Domain mapping of disease mutations (DMDM)

More...DMDMi		296453067

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003498781 – 970Zinc finger protein 845Add BLAST970

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki205Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources

Keywords - PTMi

Isopeptide bond, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q96IR2

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q96IR2

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q96IR2

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q96IR2

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q96IR2

PeptideAtlas

More...PeptideAtlasi		Q96IR2

PRoteomics IDEntifications database

More...PRIDEi		Q96IR2

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		76846

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q96IR2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q96IR2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000213799, Expressed in calcaneal tendon and 123 other tissues

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000213799, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		124863, 9 interactors

Protein interaction database and analysis system

More...IntActi		Q96IR2, 5 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000388311

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q96IR2, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q96IR2

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini8 – 81KRABPROSITE-ProRule annotationAdd BLAST74

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the krueppel C2H2-type zinc-finger protein family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri215 – 237C2H2-type 1; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri243 – 265C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri271 – 293C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri299 – 321C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri327 – 349C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri355 – 377C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri383 – 405C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri411 – 433C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri439 – 461C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri467 – 489C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri495 – 517C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri523 – 545C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri551 – 573C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri579 – 601C2H2-type 14PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri607 – 629C2H2-type 15PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri635 – 657C2H2-type 16PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri663 – 685C2H2-type 17PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri691 – 713C2H2-type 18PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri719 – 741C2H2-type 19PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri747 – 769C2H2-type 20PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri775 – 797C2H2-type 21PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri803 – 825C2H2-type 22PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri831 – 853C2H2-type 23PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri859 – 881C2H2-type 24PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri887 – 909C2H2-type 25PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri915 – 937C2H2-type 26PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri943 – 965C2H2-type 27PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1721, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000155274

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_002678_17_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q96IR2

Identification of Orthologs from Complete Genome Data

More...OMAi		IIHLGAK

Database of Orthologous Groups

More...OrthoDBi		1318335at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q96IR2

TreeFam database of animal gene trees

More...TreeFami		TF343410

Family and domain databases

Conserved Domains Database

More...CDDi		cd07765, KRAB_A-box, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR001909, KRAB
IPR036051, KRAB_dom_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01352, KRAB, 1 hit
PF00096, zf-C2H2, 24 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00349, KRAB, 1 hit
SM00355, ZnF_C2H2, 27 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF109640, SSF109640, 1 hit
SSF57667, SSF57667, 16 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50805, KRAB, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 26 hits
PS50157, ZINC_FINGER_C2H2_2, 27 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q96IR2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MALSQGLLTF RDVAIEFSQE EWKCLDPAQR TLYRDVMLEN YRNLVSLDIS 
        60         70         80         90        100
SKCMMKEFSS TAQGNTEVIH TGTLQRHERH HIGDFCFQEM EKDIHDFEFQ 
       110        120        130        140        150
WKEDERNSHE APMTEIKQLT GSTNRHDQRH AGNKPIKDQL GSSFHSHLPE 
       160        170        180        190        200
LHMFQTEGKI GNQVEKSINS ASLVSTSQRI SCRPKTHISK NYGNNFLNSS 
       210        220        230        240        250
LLTQKQEVHM REKSFQCNES GKAFNYSSVL RKHQIIHLGA KQYKCDVCGK 
       260        270        280        290        300
VFNQKRYLAC HRRCHTGKKP YKCNDCGKTF SQELTLTCHH RLHTGEKHYK 
       310        320        330        340        350
CSECGKTFSR NSALVIHKAI HTGEKSYKCN ECGKTFSQTS YLVYHRRLHT 
       360        370        380        390        400
GEKPYKCEEC DKAFSFKSNL ERHRKIHTGE KPYKCNECSR TFSRKSSLTR 
       410        420        430        440        450
HRRLHTGEKP YKCNDCGKTF SQMSSLVYHR RLHTGEKPYK CEECDEAFSF 
       460        470        480        490        500
KSNLERHRRI HTGEKPYKCN DCGKTFSQTS SLVYHRRLHT GEKPYKCEEC 
       510        520        530        540        550
DEAFSFKSNL ERHRIIHTGE KLYKCNECGK TFSRKSSLTR HCRLHTGEKP 
       560        570        580        590        600
YQCNECGKAF RGQSALIYHQ AIHGIGKLYK CNDCHQVFSN ATTIANHWRI 
       610        620        630        640        650
HNEERSYKCN RCGKFFRHRS YLAVHWRTHS GEKPYKCEEC DEAFSFKSNL 
       660        670        680        690        700
QRHRRIHTGE KPYRCNECGK TFSRKSYLTC HRRLHTGEKP YKCNECGKTF 
       710        720        730        740        750
GRNSALIIHK AIHTGEKPYK CNECGKAFSQ KSSLTCHLRL HTGEKPYKCE 
       760        770        780        790        800
ECDKVFSRKS SLEKHRRIHT GEKPYKCKVC DKAFGRDSHL AQHTRIHTGE 
       810        820        830        840        850
KPYKCNECGK NFRHNSALVI HKAIHSGEKP YKCNECGKTF RHNSALEIHK 
       860        870        880        890        900
AIHTGEKPYK CSECGKVFNR KANLSRHHRL HTGEKPYKCN KCGKVFNQQA 
       910        920        930        940        950
HLACHHRIHT GEKPYKCNEC GKTFRHNSVL VIHKTIHTGE KPYKCNECGK 
       960        970
VFNRKAKLAR HHRIHTGKKH
Length:970
Mass (Da):113,133
Last modified:May 18, 2010 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3ED3FDDF5893B5CF
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti348L → F in AAH07307 (PubMed:15489334).Curated1
Sequence conflicti537S → F in BAG58121 (PubMed:14702039).Curated1
Sequence conflicti662 – 745Missing in BAG58121 (PubMed:14702039).CuratedAdd BLAST84
Sequence conflicti807E → D in AAH07307 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK295079 mRNA Translation: BAG58121.1
AC010467 Genomic DNA No translation available.
BC007307 mRNA Translation: AAH07307.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS46170.1

NCBI Reference Sequences

More...RefSeqi		NP_001308451.1, NM_001321522.1
NP_001308452.1, NM_001321523.1
NP_001308453.1, NM_001321524.1
NP_612383.1, NM_138374.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000458035; ENSP00000388311; ENSG00000213799
ENST00000595091; ENSP00000470005; ENSG00000213799

Database of genes from NCBI RefSeq genomes

More...GeneIDi		91664

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:91664

UCSC genome browser

More...UCSCi		uc010ydv.1, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK295079 mRNA Translation: BAG58121.1
AC010467 Genomic DNA No translation available.
BC007307 mRNA Translation: AAH07307.1
CCDSiCCDS46170.1
RefSeqiNP_001308451.1, NM_001321522.1
NP_001308452.1, NM_001321523.1
NP_001308453.1, NM_001321524.1
NP_612383.1, NM_138374.2

3D structure databases

SMRiQ96IR2
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi124863, 9 interactors
IntActiQ96IR2, 5 interactors
STRINGi9606.ENSP00000388311

PTM databases

iPTMnetiQ96IR2
PhosphoSitePlusiQ96IR2

Genetic variation databases

BioMutaiZNF845
DMDMi296453067

Proteomic databases

EPDiQ96IR2
jPOSTiQ96IR2
MassIVEiQ96IR2
MaxQBiQ96IR2
PaxDbiQ96IR2
PeptideAtlasiQ96IR2
PRIDEiQ96IR2
ProteomicsDBi76846

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		32690, 73 antibodies

Genome annotation databases

EnsembliENST00000458035; ENSP00000388311; ENSG00000213799
ENST00000595091; ENSP00000470005; ENSG00000213799
GeneIDi91664
KEGGihsa:91664
UCSCiuc010ydv.1, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		91664

GeneCards: human genes, protein and diseases

More...GeneCardsi		ZNF845
HGNCiHGNC:25112, ZNF845
HPAiENSG00000213799, Low tissue specificity
neXtProtiNX_Q96IR2
OpenTargetsiENSG00000213799
PharmGKBiPA162410863
VEuPathDBiHostDB:ENSG00000213799.10

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
GeneTreeiENSGT00940000155274
HOGENOMiCLU_002678_17_0_1
InParanoidiQ96IR2
OMAiIIHLGAK
OrthoDBi1318335at2759
PhylomeDBiQ96IR2
TreeFamiTF343410

Enzyme and pathway databases

PathwayCommonsiQ96IR2

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		91664, 10 hits in 872 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		ZNF845, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		91664
PharosiQ96IR2, Tdark

Protein Ontology

More...PROi		PR:Q96IR2
RNActiQ96IR2, protein

Gene expression databases

BgeeiENSG00000213799, Expressed in calcaneal tendon and 123 other tissues

Family and domain databases

CDDicd07765, KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909, KRAB
IPR036051, KRAB_dom_sf
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF01352, KRAB, 1 hit
PF00096, zf-C2H2, 24 hits
SMARTiView protein in SMART
SM00349, KRAB, 1 hit
SM00355, ZnF_C2H2, 27 hits
SUPFAMiSSF109640, SSF109640, 1 hit
SSF57667, SSF57667, 16 hits
PROSITEiView protein in PROSITE
PS50805, KRAB, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 26 hits
PS50157, ZINC_FINGER_C2H2_2, 27 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN845_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96IR2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: May 18, 2010
Last modified: February 10, 2021
This is version 155 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
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