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Entry version 113 (13 Feb 2019)
Sequence version 2 (14 Oct 2008)
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Protein

Terminal nucleotidyltransferase 5A

Gene

TENT5A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probable nucleotidyltransferase that may act as a non-canonical poly(A) RNA polymerase.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionNucleotidyltransferase, Transferase

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Terminal nucleotidyltransferase 5ACurated (EC:2.7.7.-1 Publication)
Alternative name(s):
HBV X-transactivated gene 11 protein1 Publication
HBV XAg-transactivated protein 111 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TENT5AImported
Synonyms:C6orf37Imported, FAM46AImported, XTP111 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000112773.15

Human Gene Nomenclature Database

More...
HGNCi
HGNC:18345 TENT5A

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
611357 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q96IP4

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section provides information on the disease(s) associated with genetic variations in a given protein. The information is extracted from the scientific literature and diseases that are also described in the <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim">OMIM</a> database are represented with a <a href="http://www.uniprot.org/diseases">controlled vocabulary</a> in the following way:<p><a href='/help/involvement_in_disease' target='_top'>More...</a></p>Involvement in diseasei

Osteogenesis imperfecta 18 (OI18)1 Publication
The disease is caused by mutations affecting the gene represented in this entry.
Disease descriptionAn autosomal recessive form of osteogenesis imperfecta, a connective tissue disorder characterized by low bone mass, bone fragility and susceptibility to fractures after minimal trauma. Disease severity ranges from very mild forms without fractures to intrauterine fractures and perinatal lethality. Extraskeletal manifestations, which affect a variable number of patients, are dentinogenesis imperfecta, hearing loss, and blue sclerae. OI18 is a severe form characterized by congenital bowing of the lower limb, wormian bones, blue sclerae, vertebral collapses and multiple fractures in the first years of life.
See also OMIM:617952
Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_080798127H → R in OI18; unknown pathological significance. 1 PublicationCorresponds to variant dbSNP:rs1187611948Ensembl.1
Natural variantiVAR_080799231D → G in OI18; unknown pathological significance. 1 Publication1

Keywords - Diseasei

Disease mutation, Osteogenesis imperfecta

Organism-specific databases

DisGeNET

More...
DisGeNETi
55603

MalaCards human disease database

More...
MalaCardsi
TENT5A
MIMi617952 phenotype

Open Targets

More...
OpenTargetsi
ENSG00000112773

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA38531

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FAM46A

Domain mapping of disease mutations (DMDM)

More...
DMDMi
209572613

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002599291 – 442Terminal nucleotidyltransferase 5AAdd BLAST442

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q96IP4

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q96IP4

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q96IP4

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q96IP4

PeptideAtlas

More...
PeptideAtlasi
Q96IP4

PRoteomics IDEntifications database

More...
PRIDEi
Q96IP4

ProteomicsDB human proteome resource

More...
ProteomicsDBi
76841
76842 [Q96IP4-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q96IP4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q96IP4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Widely expressed, with preferential expression observed in the retina compared to other ocular tissues (PubMed:12054608). Also expressed in osteoblasts (PubMed:29358272).2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000112773 Expressed in 220 organ(s), highest expression level in chorionic villus

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q96IP4 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q96IP4 HS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
120744, 67 interactors

Protein interaction database and analysis system

More...
IntActi
Q96IP4, 28 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000318298

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q96IP4

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati24 – 2815
Repeati29 – 3325
Repeati34 – 3835
Repeati39 – 4345

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TENT family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3852 Eukaryota
ENOG410XTG4 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000157191

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000234733

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG057969

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q96IP4

KEGG Orthology (KO)

More...
KOi
K23033

Database of Orthologous Groups

More...
OrthoDBi
612201at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q96IP4

TreeFam database of animal gene trees

More...
TreeFami
TF315239

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR012937 TET5

The PANTHER Classification System

More...
PANTHERi
PTHR12974 PTHR12974, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07984 NTP_transf_7, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01153 DUF1693, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q96IP4-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAEGEGYFAM SEDELACSPY IPLGGDFGGG DFGGGDFGGG DFGGGGSFGG
60 70 80 90 100
HCLDYCESPT AHCNVLNWEQ VQRLDGILSE TIPIHGRGNF PTLELQPSLI
110 120 130 140 150
VKVVRRRLAE KRIGVRDVRL NGSAASHVLH QDSGLGYKDL DLIFCADLRG
160 170 180 190 200
EGEFQTVKDV VLDCLLDFLP EGVNKEKITP LTLKEAYVQK MVKVCNDSDR
210 220 230 240 250
WSLISLSNNS GKNVELKFVD SLRRQFEFSV DSFQIKLDSL LLFYECSENP
260 270 280 290 300
MTETFHPTII GESVYGDFQE AFDHLCNKII ATRNPEEIRG GGLLKYCNLL
310 320 330 340 350
VRGFRPASDE IKTLQRYMCS RFFIDFSDIG EQQRKLESYL QNHFVGLEDR
360 370 380 390 400
KYEYLMTLHG VVNESTVCLM GHERRQTLNL ITMLAIRVLA DQNVIPNVAN
410 420 430 440
VTCYYQPAPY VADANFSNYY IAQVQPVFTC QQQTYSTWLP CN
Length:442
Mass (Da):49,666
Last modified:October 14, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC72092C590C1E369
GO
Isoform 2 (identifier: Q96IP4-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MHQRYFWTDQGQVALGGHYM

Show »
Length:461
Mass (Da):51,943
Checksum:i40DEE86DB396F61A
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5TF85Q5TF85_HUMAN
Family with sequence similarity 46,...
TENT5A FAM46A, hCG_401094
523Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0Y6D7H0Y6D7_HUMAN
Terminal nucleotidyltransferase 5A
TENT5A
86Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0Y5Y3H0Y5Y3_HUMAN
Terminal nucleotidyltransferase 5A
TENT5A
88Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH00683 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti47S → T in AAM53071 (PubMed:12054608).Curated1
Sequence conflicti145C → S in AAM53071 (PubMed:12054608).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_04664924G → GGDFGG1 Publication1
Natural variantiVAR_02897839 – 43Missing 2 Publications5
Natural variantiVAR_080798127H → R in OI18; unknown pathological significance. 1 PublicationCorresponds to variant dbSNP:rs1187611948Ensembl.1
Natural variantiVAR_080799231D → G in OI18; unknown pathological significance. 1 Publication1
Natural variantiVAR_028979313T → A2 Publications1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0355021M → MHQRYFWTDQGQVALGGHYM in isoform 2. 2 Publications1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF350451 mRNA Translation: AAM53071.1
AY740520 mRNA Translation: AAW66943.1
AK000044 mRNA Translation: BAA90903.1
AK056057 mRNA No translation available.
AK292109 mRNA Translation: BAF84798.1
AL078599 Genomic DNA No translation available.
CH471051 Genomic DNA Translation: EAW48692.1
BC000683 mRNA Translation: AAH00683.1 Different initiation.
BC007351 mRNA Translation: AAH07351.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS34489.1 [Q96IP4-1]

Protein sequence database of the Protein Information Resource

More...
PIRi
JC7837

NCBI Reference Sequences

More...
RefSeqi
NP_060103.2, NM_017633.2 [Q96IP4-1]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.10784

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000320172; ENSP00000318298; ENSG00000112773 [Q96IP4-1]
ENST00000369754; ENSP00000358769; ENSG00000112773 [Q96IP4-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
55603

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:55603

UCSC genome browser

More...
UCSCi
uc003pjf.3 human [Q96IP4-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF350451 mRNA Translation: AAM53071.1
AY740520 mRNA Translation: AAW66943.1
AK000044 mRNA Translation: BAA90903.1
AK056057 mRNA No translation available.
AK292109 mRNA Translation: BAF84798.1
AL078599 Genomic DNA No translation available.
CH471051 Genomic DNA Translation: EAW48692.1
BC000683 mRNA Translation: AAH00683.1 Different initiation.
BC007351 mRNA Translation: AAH07351.1
CCDSiCCDS34489.1 [Q96IP4-1]
PIRiJC7837
RefSeqiNP_060103.2, NM_017633.2 [Q96IP4-1]
UniGeneiHs.10784

3D structure databases

ProteinModelPortaliQ96IP4
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi120744, 67 interactors
IntActiQ96IP4, 28 interactors
STRINGi9606.ENSP00000318298

PTM databases

iPTMnetiQ96IP4
PhosphoSitePlusiQ96IP4

Polymorphism and mutation databases

BioMutaiFAM46A
DMDMi209572613

Proteomic databases

EPDiQ96IP4
jPOSTiQ96IP4
MaxQBiQ96IP4
PaxDbiQ96IP4
PeptideAtlasiQ96IP4
PRIDEiQ96IP4
ProteomicsDBi76841
76842 [Q96IP4-2]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
55603
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000320172; ENSP00000318298; ENSG00000112773 [Q96IP4-1]
ENST00000369754; ENSP00000358769; ENSG00000112773 [Q96IP4-2]
GeneIDi55603
KEGGihsa:55603
UCSCiuc003pjf.3 human [Q96IP4-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
55603
DisGeNETi55603
EuPathDBiHostDB:ENSG00000112773.15

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TENT5A

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0006030
HGNCiHGNC:18345 TENT5A
MalaCardsiTENT5A
MIMi611357 gene
617952 phenotype
neXtProtiNX_Q96IP4
OpenTargetsiENSG00000112773
PharmGKBiPA38531

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3852 Eukaryota
ENOG410XTG4 LUCA
GeneTreeiENSGT00940000157191
HOGENOMiHOG000234733
HOVERGENiHBG057969
InParanoidiQ96IP4
KOiK23033
OrthoDBi612201at2759
PhylomeDBiQ96IP4
TreeFamiTF315239

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
FAM46A human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
FAM46A

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
55603

Protein Ontology

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PROi
PR:Q96IP4

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000112773 Expressed in 220 organ(s), highest expression level in chorionic villus
ExpressionAtlasiQ96IP4 baseline and differential
GenevisibleiQ96IP4 HS

Family and domain databases

InterProiView protein in InterPro
IPR012937 TET5
PANTHERiPTHR12974 PTHR12974, 1 hit
PfamiView protein in Pfam
PF07984 NTP_transf_7, 1 hit
SMARTiView protein in SMART
SM01153 DUF1693, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTET5A_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96IP4
Secondary accession number(s): A8K7U4
, Q5TF86, Q8NFZ9, Q9BW32, Q9NXV5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: October 14, 2008
Last modified: February 13, 2019
This is version 113 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  5. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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