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Entry version 131 (17 Jun 2020)
Sequence version 2 (06 Mar 2007)
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Protein

Protein N-terminal glutamine amidohydrolase

Gene

NTAQ1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei28By similarity1
Active sitei81By similarity1
Active sitei97By similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

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BioCyci
MetaCyc:ENSG00000156795-MONOMER

Protein family/group databases

MoonDB Database of extreme multifunctional and moonlighting proteins

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MoonDBi
Q96HA8 Predicted

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein N-terminal glutamine amidohydrolaseCurated (EC:3.5.1.122By similarity)
Alternative name(s):
Protein NH2-terminal glutamine deamidase
Short name:
N-terminal Gln amidase
Short name:
Nt(Q)-amidase
WDYHV motif-containing protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:NTAQ1Imported
Synonyms:C8orf32, WDYHV1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000156795.6

Human Gene Nomenclature Database

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HGNCi
HGNC:25490 NTAQ1

neXtProt; the human protein knowledge platform

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neXtProti
NX_Q96HA8

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

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OpenTargetsi
ENSG00000156795

The Pharmacogenetics and Pharmacogenomics Knowledge Base

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PharmGKBi
PA164727566

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

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Pharosi
Q96HA8 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

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BioMutai
WDYHV1

Domain mapping of disease mutations (DMDM)

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DMDMi
152112225

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002794091 – 205Protein N-terminal glutamine amidohydrolaseAdd BLAST205

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
Q96HA8

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
Q96HA8

MassIVE - Mass Spectrometry Interactive Virtual Environment

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MassIVEi
Q96HA8

MaxQB - The MaxQuant DataBase

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MaxQBi
Q96HA8

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
Q96HA8

PeptideAtlas

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PeptideAtlasi
Q96HA8

PRoteomics IDEntifications database

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PRIDEi
Q96HA8

ProteomicsDB: a multi-organism proteome resource

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ProteomicsDBi
3924
76725 [Q96HA8-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

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iPTMneti
Q96HA8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

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PhosphoSitePlusi
Q96HA8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSG00000156795 Expressed in heart and 213 other tissues

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
Q96HA8 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

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Genevisiblei
Q96HA8 HS

Organism-specific databases

Human Protein Atlas

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HPAi
ENSG00000156795 Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Monomer.

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Q96HA8
With#Exp.IntAct
AARD [Q4LEZ3]3EBI-741158,EBI-5463075
ACD [A0A590TQL1]3EBI-741158,EBI-23197871
ACOT13 [Q9NPJ3]3EBI-741158,EBI-1045357
ACTB [P60709]6EBI-741158,EBI-353944
ACTG1 [P63261]7EBI-741158,EBI-351292
ACTN2 [P35609]3EBI-741158,EBI-77797
ACY1 [Q03154]3EBI-741158,EBI-742064
ADAMTSL4 - isoform 3 [Q6UY14-3]3EBI-741158,EBI-10173507
AGR2 [O95994]3EBI-741158,EBI-712648
AGR3 [Q8TD06]3EBI-741158,EBI-3925742
AIMP2 [Q13155]3EBI-741158,EBI-745226
AKIRIN2 [Q53H80]3EBI-741158,EBI-742928
AMOT [A2BDD9]3EBI-741158,EBI-17286414
AMOT - isoform 2 [Q4VCS5-2]3EBI-741158,EBI-3891843
AMOTL2 - isoform 4 [Q9Y2J4-4]3EBI-741158,EBI-10187270
AMPD2 - isoform Ex1A-2-3 [Q01433-2]3EBI-741158,EBI-11957578
ANKRD11 [X5D778]3EBI-741158,EBI-17183751
ANKRD36B - isoform 4 [Q8N2N9-4]3EBI-741158,EBI-12170453
AOC1 [P19801]3EBI-741158,EBI-12826295
APIP [Q96GX9]5EBI-741158,EBI-359248
ARID4B - isoform 3 [Q4LE39-3]3EBI-741158,EBI-11957452
ARL6IP1 [Q15041]3EBI-741158,EBI-714543
ASL [P04424]7EBI-741158,EBI-750131
ATP6V1G1 [O75348]3EBI-741158,EBI-711802
BANF2 - isoform 2 [Q9H503-2]3EBI-741158,EBI-11977289
BEND5 [Q7L4P6]3EBI-741158,EBI-724373
BIRC2 [Q13490]6EBI-741158,EBI-514538
BIRC7 [Q96CA5]3EBI-741158,EBI-517623
BLMH [Q13867]4EBI-741158,EBI-718504
BLZF1 [Q9H2G9]3EBI-741158,EBI-2548012
BOLA2B [A0A087WZT3]3EBI-741158,EBI-12006120
BORCS6 [Q96GS4]3EBI-741158,EBI-10193358
BPIFB3 [P59826]3EBI-741158,EBI-1055244
BTBD1 [Q9H0C5]3EBI-741158,EBI-935503
BTBD2 [Q9BX70]3EBI-741158,EBI-710091
BTBD6 - isoform 2 [Q96KE9-2]3EBI-741158,EBI-12012762
C1orf50 [Q9BV19]6EBI-741158,EBI-2874661
CAMK2A [Q9UQM7]3EBI-741158,EBI-1383687
CAPN3 [P20807]3EBI-741158,EBI-5655000
CAPN3 - isoform IV [P20807-4]3EBI-741158,EBI-11532021
CARD9 - isoform 2 [Q9H257-2]3EBI-741158,EBI-11530605
CASP6 [P55212]3EBI-741158,EBI-718729
CAVIN4 [Q5BKX8]3EBI-741158,EBI-12836558
CBY2 - isoform 2 [Q8NA61-2]5EBI-741158,EBI-11524851
CCDC102B [Q68D86]4EBI-741158,EBI-10171570
CCDC115 [Q96NT0]3EBI-741158,EBI-2810325
CCDC152 [Q4G0S7]3EBI-741158,EBI-18398007
CCDC184 [Q52MB2]3EBI-741158,EBI-10179526
CCDC197 [Q8NCU1]3EBI-741158,EBI-750686
CCHCR1 - isoform 3 [Q8TD31-3]3EBI-741158,EBI-10175300
CCNB1IP1 [Q9NPC3]3EBI-741158,EBI-745269
CD22 - isoform 5 [P20273-5]3EBI-741158,EBI-13320645
CDA [P32320]9EBI-741158,EBI-9250559
CDCA8 [Q53HL2]3EBI-741158,EBI-979174
CDK2AP1 [O14519]3EBI-741158,EBI-1052532
CDKN2AIPNL [Q96HQ2]3EBI-741158,EBI-10038935
CDR2 [Q01850]4EBI-741158,EBI-1181367
CENPP [Q6IPU0]3EBI-741158,EBI-10250303
CEP170B - isoform 3 [Q9Y4F5-3]3EBI-741158,EBI-12950757
CEP55 [Q53EZ4]5EBI-741158,EBI-747776
CEP70 [Q8NHQ1]3EBI-741158,EBI-739624
CEP85 - isoform 3 [Q6P2H3-3]3EBI-741158,EBI-12368239
CGGBP1 [Q9UFW8]3EBI-741158,EBI-723153
CHCHD3 [Q9NX63]3EBI-741158,EBI-743375
CHMP4A - isoform 2 [Q9BY43-2]3EBI-741158,EBI-12178895
CMTM5 - isoform 2 [Q96DZ9-2]3EBI-741158,EBI-11522780
COG6 [Q9Y2V7]5EBI-741158,EBI-3866319
COIL [P38432]3EBI-741158,EBI-945751
CRYAA [P02489]7EBI-741158,EBI-6875961
CSNK2B [P67870]3EBI-741158,EBI-348169
CT45A1 [Q5HYN5]3EBI-741158,EBI-12051833
CTAG1A [P78358]3EBI-741158,EBI-1188472
CTH [P32929]3EBI-741158,EBI-749763
CUEDC1 [Q9NWM3]3EBI-741158,EBI-5838167
CUTC [Q9NTM9]3EBI-741158,EBI-714918
CYSRT1 [A8MQ03]3EBI-741158,EBI-3867333
DAB1 [O75553]3EBI-741158,EBI-7875264
DCTPP1 [Q9H773]5EBI-741158,EBI-723569
DEUP1 [Q05D60]3EBI-741158,EBI-748597
DHPS [P49366]3EBI-741158,EBI-741925
DNAL4 [O96015]3EBI-741158,EBI-742362
DYNLT1 [P63172]3EBI-741158,EBI-1176455
EDARADD [Q8WWZ3]4EBI-741158,EBI-2949647
EGLN3 [Q9H6Z9]3EBI-741158,EBI-1175354
EIF2B1 [Q14232]7EBI-741158,EBI-491065
EIF4G1 - isoform 9 [Q04637-9]3EBI-741158,EBI-12012124
EMILIN3 [Q9NT22]3EBI-741158,EBI-3197883
EP400 [A0A0A0MR80]3EBI-741158,EBI-12089140
EPN3 [I6L9I8]3EBI-741158,EBI-12866582
ETV6 [P41212]3EBI-741158,EBI-1372759
EXOSC8 [Q96B26]3EBI-741158,EBI-371922
FAM136A [Q96C01]3EBI-741158,EBI-373319
FAM72A [Q5TYM5]3EBI-741158,EBI-10237116
FAM72D [Q6L9T8]3EBI-741158,EBI-18397873
FKBP6 [O75344]3EBI-741158,EBI-744771
FTH1 [Q6NZ44]3EBI-741158,EBI-10180219
FTL [P02792]3EBI-741158,EBI-713279
GADD45GIP1 [Q8TAE8]3EBI-741158,EBI-372506
GAS7 [O60861]4EBI-741158,EBI-2683717
GAS7 - isoform 1 [O60861-1]5EBI-741158,EBI-11745923
GCSAML [Q5JQS6]3EBI-741158,EBI-17857617
GFAP [P14136]3EBI-741158,EBI-744302
GMDS [O60547]6EBI-741158,EBI-746373
GNG3 [P63215]3EBI-741158,EBI-1046668
GNMT [Q14749]5EBI-741158,EBI-744239
GNPDA2 - isoform 2 [Q8TDQ7-2]3EBI-741158,EBI-12197555
GOLGA2 [Q08379]8EBI-741158,EBI-618309
GOLGA6L9 [A6NEM1]3EBI-741158,EBI-5916454
GPX7 [Q96SL4]3EBI-741158,EBI-749411
GRAMD4 [Q6IC98]3EBI-741158,EBI-10962409
GSTA4 [O15217]3EBI-741158,EBI-752440
GSTO2 [Q9H4Y5]3EBI-741158,EBI-10194609
GTF2H2C_2 [Q6P1K8]3EBI-741158,EBI-8469755
HAUS8 [Q9BT25]3EBI-741158,EBI-2558143
HBQ1 [P09105]3EBI-741158,EBI-10193656
HBZ [P02008]3EBI-741158,EBI-719843
HEATR5A - isoform 3 [Q86XA9-3]3EBI-741158,EBI-17981660
HEL-S-182mP [V9HW60]3EBI-741158,EBI-10180762
HEL-S-70 [V9HW80]3EBI-741158,EBI-10175326
HGD [Q93099]3EBI-741158,EBI-3907760
HIGD1C [A8MV81]3EBI-741158,EBI-12809676
HMG20A [Q9NP66]5EBI-741158,EBI-740641
HOMER3 [Q9NSC5]3EBI-741158,EBI-748420
HOXB6 [P17509]3EBI-741158,EBI-741308
HPRT1 [P00492]10EBI-741158,EBI-748210
HSD17B14 [Q9BPX1]13EBI-741158,EBI-742664
HSF2BP [O75031]3EBI-741158,EBI-7116203
HSPE1 [P61604]3EBI-741158,EBI-711483
HUS1 [O60921]3EBI-741158,EBI-1056174
HYPM [O75409]3EBI-741158,EBI-6447217
IL16 - isoform 2 [Q14005-2]3EBI-741158,EBI-17178971
IL31 [Q6EBC2]3EBI-741158,EBI-18286692
INCA1 [Q0VD86]5EBI-741158,EBI-6509505
ISCA2 [Q86U28]3EBI-741158,EBI-10258659
ITGB3BP [Q13352]3EBI-741158,EBI-712105
JUP [P14923]3EBI-741158,EBI-702484
KATNBL1 [Q9H079]3EBI-741158,EBI-715394
KCNH1 [O95259]3EBI-741158,EBI-2909270
KCTD1 [Q719H9]4EBI-741158,EBI-9027502
KCTD10 [Q9H3F6]3EBI-741158,EBI-2505886
KCTD13 [Q8WZ19]3EBI-741158,EBI-742916
KCTD15 - isoform 2 [Q96SI1-2]3EBI-741158,EBI-12382297
KCTD21 [Q4G0X4]3EBI-741158,EBI-11976683
KCTD4 [Q8WVF5]3EBI-741158,EBI-741463
KCTD6 [Q8NC69]3EBI-741158,EBI-2511344
KCTD7 - isoform 2 [Q96MP8-2]3EBI-741158,EBI-11954971
KCTD9 [Q7L273]3EBI-741158,EBI-4397613
KEAP1 [Q14145]3EBI-741158,EBI-751001
KIF21B - isoform 4 [O75037-4]3EBI-741158,EBI-12897871
KLHL12 [Q53G59]8EBI-741158,EBI-740929
KLHL2 [O95198]3EBI-741158,EBI-746999
KLHL20 [Q9BS75]5EBI-741158,EBI-10693436
KRT27 [Q7Z3Y8]3EBI-741158,EBI-3044087
KRT31 [Q15323]3EBI-741158,EBI-948001
KRTAP10-5 [P60370]3EBI-741158,EBI-10172150
KRTAP10-7 [P60409]3EBI-741158,EBI-10172290
KRTAP19-2 [Q3LHN2]5EBI-741158,EBI-12196745
KRTAP19-6 [Q3LI70]3EBI-741158,EBI-12805508
KRTAP3-1 [Q9BYR8]3EBI-741158,EBI-9996449
KRTAP3-3 [Q9BYR6]3EBI-741158,EBI-3957694
KRTAP4-2 [Q9BYR5]3EBI-741158,EBI-10172511
KRTAP5-9 [P26371]6EBI-741158,EBI-3958099
KRTAP6-1 [Q3LI64]3EBI-741158,EBI-12111050
KRTAP9-2 [Q9BYQ4]6EBI-741158,EBI-1044640
KRTAP9-4 [Q9BYQ2]3EBI-741158,EBI-10185730
KRTAP9-8 [Q9BYQ0]3EBI-741158,EBI-11958364
L3MBTL3 - isoform 2 [Q96JM7-2]3EBI-741158,EBI-11985629
LCE1C [Q5T751]3EBI-741158,EBI-12224199
LCE1D [Q5T752]3EBI-741158,EBI-11741311
LCE1E [Q5T753]3EBI-741158,EBI-11955335
LCE1F [Q5T754]3EBI-741158,EBI-11958008
LCE2C [Q5TA81]3EBI-741158,EBI-11973993
LCE5A [Q5TCM9]3EBI-741158,EBI-11955689
LDB2 [O43679]3EBI-741158,EBI-2865580
LENG1 [Q96BZ8]3EBI-741158,EBI-726510
LGALS2 [P05162]3EBI-741158,EBI-7181544
LGALS9B [Q3B8N2]3EBI-741158,EBI-10240775
LIN7B [Q9HAP6]3EBI-741158,EBI-821335
LMO1 [P25800]3EBI-741158,EBI-8639312
LMO2 - isoform 3 [P25791-3]3EBI-741158,EBI-11959475
LMO3 - isoform 4 [Q8TAP4-4]3EBI-741158,EBI-11742507
LONRF1 [Q17RB8]4EBI-741158,EBI-2341787
LRIF1 [Q5T3J3]3EBI-741158,EBI-473196
LRRC73 [Q5JTD7]3EBI-741158,EBI-12003882
LSM12 [Q3MHD2]3EBI-741158,EBI-725133
LSM14B - isoform 2 [Q9BX40-2]3EBI-741158,EBI-19133880
LZTFL1 [Q9NQ48]4EBI-741158,EBI-2824799
LZTS1 [Q9Y250]3EBI-741158,EBI-1216080
LZTS2 [Q9BRK4]3EBI-741158,EBI-741037
MAB21L3 [Q8N8X9]3EBI-741158,EBI-10268010
MAD1L1 [Q9Y6D9]3EBI-741158,EBI-742610
MAGEA11 [P43364]3EBI-741158,EBI-739552
MAGEA11 - isoform 2 [P43364-2]3EBI-741158,EBI-10178634
MAGEA12 [P43365]3EBI-741158,EBI-749530
MAGEA2B [P43356]5EBI-741158,EBI-5650739
MALSU1 [Q96EH3]3EBI-741158,EBI-2339737
MARCHF10 [Q8NA82]3EBI-741158,EBI-2341554
MATN4 - isoform 2 [O95460-2]3EBI-741158,EBI-12072296
MED22 - isoform Surf5A [Q15528-2]3EBI-741158,EBI-12954271
MIF [P14174]4EBI-741158,EBI-372712
MIF4GD - isoform 2 [A9UHW6-2]3EBI-741158,EBI-9118295
MIPOL1 [Q8TD10]3EBI-741158,EBI-2548751
MIS18A [Q9NYP9]3EBI-741158,EBI-1104552
MITD1 [Q8WV92]3EBI-741158,EBI-2691489
MOB2 [Q70IA6]3EBI-741158,EBI-2558739
MORN3 [Q6PF18]3EBI-741158,EBI-9675802
MPLKIP [Q8TAP9]3EBI-741158,EBI-11603426
MRFAP1L1 [Q96HT8]3EBI-741158,EBI-748896
MRPL12 [P52815]3EBI-741158,EBI-358272
MTHFD2L - isoform 3 [Q9H903-3]3EBI-741158,EBI-14202147
MTUS2 [Q5JR59]3EBI-741158,EBI-742948
MTUS2 - isoform 2 [Q5JR59-3]5EBI-741158,EBI-11522433
MVP [Q14764]3EBI-741158,EBI-2816254
MXRA8 [Q9BRK3]3EBI-741158,EBI-11721798
MYD88 [Q99836]3EBI-741158,EBI-447677
N4BP3 [O15049]3EBI-741158,EBI-2512055
NAB2 [Q15742]3EBI-741158,EBI-8641936
NADSYN1 [Q6IA69]3EBI-741158,EBI-748610
NAGK - isoform 2 [Q9UJ70-2]5EBI-741158,EBI-11526455
NDUFAB1 [O14561]3EBI-741158,EBI-1246261
NECAB2 - isoform 2 [Q7Z6G3-2]8EBI-741158,EBI-10172876
NME1 [P15531]8EBI-741158,EBI-741141
NPL [Q9BXD5]3EBI-741158,EBI-10287915
NR5A1 [Q13285]3EBI-741158,EBI-874629
NT5C1A [Q9BXI3]6EBI-741158,EBI-10441581
NUDT14 [O95848]4EBI-741158,EBI-536866
NUDT16L1 [Q9BRJ7]3EBI-741158,EBI-2949792
NUDT21 [O43809]5EBI-741158,EBI-355720
OOEP [A6NGQ2]3EBI-741158,EBI-18583589
PAK5 [Q9P286]3EBI-741158,EBI-741896
PCBD1 [P61457]4EBI-741158,EBI-740475
PFDN5 [Q99471]3EBI-741158,EBI-357275
PGPEP1 - isoform 2 [Q9NXJ5-2]3EBI-741158,EBI-12813581
PIH1D2 [Q8WWB5]3EBI-741158,EBI-10232538
PLA2G10 [O15496]4EBI-741158,EBI-726466
PLCD1 [P51178]3EBI-741158,EBI-4405387
PLEKHB2 [Q96CS7]5EBI-741158,EBI-373552
PLEKHJ1 [Q9NW61]3EBI-741158,EBI-1057560
PNMA1 [Q8ND90]6EBI-741158,EBI-302345
PNMA2 [Q9UL42]3EBI-741158,EBI-302355
PNMA5 [Q96PV4]7EBI-741158,EBI-10171633
POLR2J [P52435]3EBI-741158,EBI-394753
POMC [P01189]3EBI-741158,EBI-12219503
PPCDC [Q96CD2]6EBI-741158,EBI-724333
PPM1K [Q8N3J5]3EBI-741158,EBI-3923368
PPP1R27 [Q86WC6]3EBI-741158,EBI-5235602
PRKAR1B [P31321]3EBI-741158,EBI-2805516
PRMT1 [Q99873]3EBI-741158,EBI-78738
PRMT5 [O14744]3EBI-741158,EBI-351098
PRPS2 [P11908]4EBI-741158,EBI-4290895
PRR20D [P86480]3EBI-741158,EBI-12754095
PRR23B [Q6ZRT6]3EBI-741158,EBI-12845180
PRTFDC1 [Q9NRG1]3EBI-741158,EBI-739759
PS1TP5BP1 [Q1KLZ0]3EBI-741158,EBI-9978131
PSMB5 [P28074]3EBI-741158,EBI-357828
PSME3 [P61289]5EBI-741158,EBI-355546
PTS [Q03393]3EBI-741158,EBI-712344
PYCR3 [Q53H96]3EBI-741158,EBI-2959680
PYGM [P11217]4EBI-741158,EBI-357469
RAB42 - isoform 2 [Q8N4Z0-1]3EBI-741158,EBI-17857145
RABAC1 [Q9UI14]9EBI-741158,EBI-712367
RAD54L [Q92698]4EBI-741158,EBI-5333483
RASAL3 [Q86YV0]3EBI-741158,EBI-3437896
RBM20 [Q5T481]3EBI-741158,EBI-11352885
RBM45 - isoform 3 [Q8IUH3-3]3EBI-741158,EBI-10964453
RBM48 [Q5RL73]3EBI-741158,EBI-473821
RBPMS [Q93062]3EBI-741158,EBI-740322
RD3 [Q7Z3Z2]3EBI-741158,EBI-10257497
REEP6 - isoform 2 [Q96HR9-2]3EBI-741158,EBI-14065960
RHOQ [P17081]3EBI-741158,EBI-689202
RILPL1 - isoform 3 [Q5EBL4-3]3EBI-741158,EBI-12072024
RNF138 [Q8WVD3]3EBI-741158,EBI-749039
RNF4 [P78317]3EBI-741158,EBI-2340927
ROPN1 [Q9HAT0]5EBI-741158,EBI-1378139
RPIA [P49247]8EBI-741158,EBI-744831
RUSC1 [Q9BVN2]3EBI-741158,EBI-6257312
S100A11 [P31949]3EBI-741158,EBI-701862
SAP18 [O00422]3EBI-741158,EBI-1044156
SARS2 [Q9NP81]3EBI-741158,EBI-1049768
SAT1 [P21673]3EBI-741158,EBI-711613
SCARA5 - isoform 2 [Q6ZMJ2-2]3EBI-741158,EBI-12823227
SELENOV [P59797]3EBI-741158,EBI-10216195
SEPTIN14 [Q6ZU15]3EBI-741158,EBI-2009297
SEPTIN3 [Q9UH03]3EBI-741158,EBI-727037
SFN [P31947]4EBI-741158,EBI-476295
SH3GLB2 [Q9NR46]3EBI-741158,EBI-749607
SIAH1 [Q8IUQ4]3EBI-741158,EBI-747107
SIKE1 [Q9BRV8]3EBI-741158,EBI-1773646
SIVA1 - isoform 2 [O15304-2]3EBI-741158,EBI-12372219
SLAIN1 [Q8ND83]3EBI-741158,EBI-10269374
SLC15A2 [Q16348]3EBI-741158,EBI-12806032
SLPI [P03973]3EBI-741158,EBI-355293
SMAP1 - isoform 2 [Q8IYB5-2]3EBI-741158,EBI-12061577
SNAP29 [O95721]3EBI-741158,EBI-490676
SNRPD3 [P62318]3EBI-741158,EBI-372789
SPANXB1 [Q9NS25]3EBI-741158,EBI-17197485
SPATA32 [Q96LK8]3EBI-741158,EBI-12849978
SPDYE4 [A6NLX3]3EBI-741158,EBI-12047907
SPINDOC [Q9BUA3]3EBI-741158,EBI-1773488
SPRYD7 - isoform 2 [Q5W111-2]3EBI-741158,EBI-12408727
SSNA1 [O43805]3EBI-741158,EBI-2515299
STH [Q8IWL8]3EBI-741158,EBI-12843506
STMN2 [Q93045]3EBI-741158,EBI-714194
STN1 [Q9H668]3EBI-741158,EBI-746930
STX11 [O75558]3EBI-741158,EBI-714135
SYNGAP1 [Q96PV0]3EBI-741158,EBI-2682386
TAX1BP1 [Q86VP1]3EBI-741158,EBI-529518
TBX15 [Q96SF7]3EBI-741158,EBI-10191361
TCL1A [P56279]5EBI-741158,EBI-749995
TCP10L [Q8TDR4]3EBI-741158,EBI-3923210
TEKT1 [Q969V4]3EBI-741158,EBI-10180409
TEPSIN [Q96N21]3EBI-741158,EBI-11139477
THAP1 [Q9NVV9]8EBI-741158,EBI-741515
THAP6 [Q8TBB0]3EBI-741158,EBI-3925505
THAP7 [Q9BT49]3EBI-741158,EBI-741350
THG1L [Q9NWX6]3EBI-741158,EBI-746510
TICAM2 [Q86XR7]3EBI-741158,EBI-525927
TIFA [Q96CG3]3EBI-741158,EBI-740711
TLE5 - isoform 2 [Q08117-2]5EBI-741158,EBI-11741437
TMEM239 [Q8WW34]3EBI-741158,EBI-9675724
TNFAIP1 [Q13829]3EBI-741158,EBI-2505861
TNIP3 [Q96KP6]3EBI-741158,EBI-2509913
TNR [A1L306]3EBI-741158,EBI-10182881
TOLLIP [Q9H0E2]4EBI-741158,EBI-74615
TRAF3 [Q13114]3EBI-741158,EBI-357631
TRAF5 [O00463]3EBI-741158,EBI-523498
TRIM23 [P36406]3EBI-741158,EBI-740098
TRIM27 [P14373]6EBI-741158,EBI-719493
TRIM32 [Q13049]3EBI-741158,EBI-742790
TRIM5 - isoform Gamma [Q9C035-3]3EBI-741158,EBI-12840050
TRIM54 [Q9BYV2]6EBI-741158,EBI-2130429
TRIM69 - isoform 2 [Q86WT6-2]3EBI-741158,EBI-11525489
TRIM74 - isoform 2 [Q86UV6-2]3EBI-741158,EBI-10259086
TRIM9 [Q9C026]3EBI-741158,EBI-720828
TRIP13 [Q15645]3EBI-741158,EBI-358993
TSC22D1 [Q15714]4EBI-741158,EBI-712609
TSC22D1 - isoform 2 [Q15714-2]3EBI-741158,EBI-12034704
TSN [Q15631]3EBI-741158,EBI-1044160
UFC1 [Q9Y3C8]3EBI-741158,EBI-1045733
UNKL - isoform 5 [Q9H9P5-5]3EBI-741158,EBI-12817837
VAC14 [Q08AM6]5EBI-741158,EBI-2107455
VCP [P55072]3EBI-741158,EBI-355164
VDR - isoform 2 [P11473-2]3EBI-741158,EBI-12874016
VPS37C [A5D8V6]6EBI-741158,EBI-2559305
VXN [Q8TAG6]3EBI-741158,EBI-12071548
XIAP [P98170]4EBI-741158,EBI-517127
ZBED1 [O96006]3EBI-741158,EBI-740037
ZBTB8A [Q96BR9]3EBI-741158,EBI-742740
ZBTB8B [Q8NAP8]3EBI-741158,EBI-17494306
ZC2HC1C - isoform 2 [Q53FD0-2]3EBI-741158,EBI-14104088
ZCCHC17 [Q9NP64]3EBI-741158,EBI-746345
ZNF165 [P49910]3EBI-741158,EBI-741694
ZNF341 [Q9BYN7]3EBI-741158,EBI-9089622
ZNF436 [Q9C0F3]3EBI-741158,EBI-8489702
ZNF511 [Q8NB15]3EBI-741158,EBI-10269136
ZNF618 [Q5T7W0]3EBI-741158,EBI-6255994
ZSCAN16 [Q9H4T2]3EBI-741158,EBI-723596

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

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BioGRIDi
120405, 156 interactors

Protein interaction database and analysis system

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IntActi
Q96HA8, 422 interactors

Molecular INTeraction database

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MINTi
Q96HA8

STRING: functional protein association networks

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STRINGi
9606.ENSP00000287387

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

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RNActi
Q96HA8 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1205
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q96HA8

Database of comparative protein structure models

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ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

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PDBe-KBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

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EvolutionaryTracei
Q96HA8

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the NTAQ1 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG3261 Eukaryota
ENOG4111G3S LUCA

Ensembl GeneTree

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GeneTreei
ENSGT00390000014398

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

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HOGENOMi
CLU_091083_1_0_1

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
Q96HA8

KEGG Orthology (KO)

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KOi
K21286

Identification of Orthologs from Complete Genome Data

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OMAi
VWKLCEY

Database of Orthologous Groups

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OrthoDBi
1337506at2759

Database for complete collections of gene phylogenies

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PhylomeDBi
Q96HA8

TreeFam database of animal gene trees

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TreeFami
TF105807

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

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Gene3Di
3.10.620.10, 1 hit

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR037132 N_Gln_amidohydro_ab_roll_sf
IPR039733 NTAQ1
IPR023128 Prot_N_Gln_amidohydro_ab_roll

The PANTHER Classification System

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PANTHERi
PTHR13035 PTHR13035, 1 hit

Pfam protein domain database

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Pfami
View protein in Pfam
PF09764 Nt_Gln_amidase, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 6 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q96HA8-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MEGNGPAAVH YQPASPPRDA CVYSSCYCEE NIWKLCEYIK NHDQYPLEEC
60 70 80 90 100
YAVFISNERK MIPIWKQQAR PGDGPVIWDY HVVLLHVSSG GQNFIYDLDT
110 120 130 140 150
VLPFPCLFDT YVEDAFKSDD DIHPQFRRKF RVIRADSYLK NFASDRSHMK
160 170 180 190 200
DSSGNWREPP PPYPCIETGD SKMNLNDFIS MDPKVGWGAV YTLSEFTHRF

GSKNC
Length:205
Mass (Da):23,680
Last modified:March 6, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF858AB0C73928CA9
GO
Isoform 2 (identifier: Q96HA8-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-60: Missing.

Show »
Length:145
Mass (Da):16,736
Checksum:iAC61BBE11D3642F1
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E5RHC2E5RHC2_HUMAN
Protein N-terminal glutamine amidoh...
WDYHV1
196Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RIY9E5RIY9_HUMAN
Protein N-terminal glutamine amidoh...
WDYHV1
57Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3B3ITD7A0A3B3ITD7_HUMAN
Protein N-terminal glutamine amidoh...
WDYHV1
147Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3B3ITI2A0A3B3ITI2_HUMAN
Protein N-terminal glutamine amidoh...
WDYHV1
127Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YBV4H0YBV4_HUMAN
Protein N-terminal glutamine amidoh...
WDYHV1
63Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3B3IS49A0A3B3IS49_HUMAN
Protein N-terminal glutamine amidoh...
WDYHV1
48Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_03088232I → V1 PublicationCorresponds to variant dbSNP:rs6999234Ensembl.1
Natural variantiVAR_03088393N → S1 PublicationCorresponds to variant dbSNP:rs7014678Ensembl.1
Natural variantiVAR_030884116F → I1 PublicationCorresponds to variant dbSNP:rs6470147Ensembl.1
Natural variantiVAR_030885134R → C1 PublicationCorresponds to variant dbSNP:rs3824250Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0552681 – 60Missing in isoform 2. 1 PublicationAdd BLAST60

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AK001066 mRNA Translation: BAA91488.1
AK293492 mRNA Translation: BAG56979.1
AC021305 Genomic DNA No translation available.
CH471060 Genomic DNA Translation: EAW92038.1
BC008781 mRNA Translation: AAH08781.1

The Consensus CDS (CCDS) project

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CCDSi
CCDS6344.1 [Q96HA8-1]
CCDS64965.1 [Q96HA8-2]

NCBI Reference Sequences

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RefSeqi
NP_001269953.1, NM_001283024.1 [Q96HA8-2]
NP_060494.1, NM_018024.2 [Q96HA8-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

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Ensembli
ENST00000287387; ENSP00000287387; ENSG00000156795 [Q96HA8-1]
ENST00000523984; ENSP00000430427; ENSG00000156795 [Q96HA8-2]
ENST00000524254; ENSP00000497832; ENSG00000156795 [Q96HA8-2]

Database of genes from NCBI RefSeq genomes

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GeneIDi
55093

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
hsa:55093

UCSC genome browser

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UCSCi
uc003yqn.3 human [Q96HA8-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK001066 mRNA Translation: BAA91488.1
AK293492 mRNA Translation: BAG56979.1
AC021305 Genomic DNA No translation available.
CH471060 Genomic DNA Translation: EAW92038.1
BC008781 mRNA Translation: AAH08781.1
CCDSiCCDS6344.1 [Q96HA8-1]
CCDS64965.1 [Q96HA8-2]
RefSeqiNP_001269953.1, NM_001283024.1 [Q96HA8-2]
NP_060494.1, NM_018024.2 [Q96HA8-1]

3D structure databases

Select the link destinations:

Protein Data Bank Europe

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PDBei

Protein Data Bank RCSB

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RCSB PDBi

Protein Data Bank Japan

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PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3C9QX-ray1.50A2-205[»]
4W79X-ray1.50A2-202[»]
6KGJX-ray1.80A/B2-202[»]
SMRiQ96HA8
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi120405, 156 interactors
IntActiQ96HA8, 422 interactors
MINTiQ96HA8
STRINGi9606.ENSP00000287387

Protein family/group databases

MoonDBiQ96HA8 Predicted

PTM databases

iPTMnetiQ96HA8
PhosphoSitePlusiQ96HA8

Polymorphism and mutation databases

BioMutaiWDYHV1
DMDMi152112225

Proteomic databases

EPDiQ96HA8
jPOSTiQ96HA8
MassIVEiQ96HA8
MaxQBiQ96HA8
PaxDbiQ96HA8
PeptideAtlasiQ96HA8
PRIDEiQ96HA8
ProteomicsDBi3924
76725 [Q96HA8-1]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

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Antibodypediai
13855 62 antibodies

The DNASU plasmid repository

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DNASUi
55093

Genome annotation databases

EnsembliENST00000287387; ENSP00000287387; ENSG00000156795 [Q96HA8-1]
ENST00000523984; ENSP00000430427; ENSG00000156795 [Q96HA8-2]
ENST00000524254; ENSP00000497832; ENSG00000156795 [Q96HA8-2]
GeneIDi55093
KEGGihsa:55093
UCSCiuc003yqn.3 human [Q96HA8-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
55093
EuPathDBiHostDB:ENSG00000156795.6

GeneCards: human genes, protein and diseases

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GeneCardsi
WDYHV1
HGNCiHGNC:25490 NTAQ1
HPAiENSG00000156795 Low tissue specificity
neXtProtiNX_Q96HA8
OpenTargetsiENSG00000156795
PharmGKBiPA164727566

GenAtlas: human gene database

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GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3261 Eukaryota
ENOG4111G3S LUCA
GeneTreeiENSGT00390000014398
HOGENOMiCLU_091083_1_0_1
InParanoidiQ96HA8
KOiK21286
OMAiVWKLCEY
OrthoDBi1337506at2759
PhylomeDBiQ96HA8
TreeFamiTF105807

Enzyme and pathway databases

BioCyciMetaCyc:ENSG00000156795-MONOMER

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
55093 2 hits in 790 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
WDYHV1 human
EvolutionaryTraceiQ96HA8

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
C8orf32

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
55093
PharosiQ96HA8 Tdark

Protein Ontology

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PROi
PR:Q96HA8
RNActiQ96HA8 protein

Gene expression databases

BgeeiENSG00000156795 Expressed in heart and 213 other tissues
ExpressionAtlasiQ96HA8 baseline and differential
GenevisibleiQ96HA8 HS

Family and domain databases

Gene3Di3.10.620.10, 1 hit
InterProiView protein in InterPro
IPR037132 N_Gln_amidohydro_ab_roll_sf
IPR039733 NTAQ1
IPR023128 Prot_N_Gln_amidohydro_ab_roll
PANTHERiPTHR13035 PTHR13035, 1 hit
PfamiView protein in Pfam
PF09764 Nt_Gln_amidase, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNTAQ1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96HA8
Secondary accession number(s): B4DE68, Q9NW95
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 6, 2007
Last sequence update: March 6, 2007
Last modified: June 17, 2020
This is version 131 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
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