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UniProtKB - Q96H78 (S2544_HUMAN)

Entry version 155 (23 Feb 2022)
Sequence version 1 (01 Dec 2001)
Previous versions | rss
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Protein

Solute carrier family 25 member 44

Gene

SLC25A44

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Mitochondrial solute transporter which transports branched-chain amino acid (BCAA; valine, leucine and isoleucine) into mitochondria in brown adipose tissue (BAT) (By similarity).

BAT is involved in BCAA catabolism and actively utilizes BCAA in the mitochondria for thermogenesis (PubMed:31435015).

By similarity1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processAmino-acid transport, Transport

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q96H78

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-70895, Branched-chain amino acid catabolism

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		Q96H78

Protein family/group databases

Transport Classification Database

More...TCDBi		2.A.29.14.7, the mitochondrial carrier (mc) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Solute carrier family 25 member 44
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SLC25A441 PublicationImported
Synonyms:KIAA0446
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:29036, SLC25A44

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		610824, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q96H78

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000160785

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei20 – 42Helical; Name=1Sequence analysisAdd BLAST23
Transmembranei71 – 90Helical; Name=2Sequence analysisAdd BLAST20
Transmembranei113 – 133Helical; Name=3Sequence analysisAdd BLAST21
Transmembranei185 – 201Helical; Name=4Sequence analysisAdd BLAST17
Transmembranei222 – 239Helical; Name=5Sequence analysisAdd BLAST18
Transmembranei278 – 296Helical; Name=6Sequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane, Mitochondrion

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		9673

Open Targets

More...OpenTargetsi		ENSG00000160785

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA162403705

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q96H78, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		SLC25A44

Domain mapping of disease mutations (DMDM)

More...DMDMi		74751902

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002530641 – 314Solute carrier family 25 member 44Add BLAST314

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q96H78

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q96H78

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q96H78

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q96H78

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q96H78

PeptideAtlas

More...PeptideAtlasi		Q96H78

PRoteomics IDEntifications database

More...PRIDEi		Q96H78

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		76709

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q96H78

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q96H78

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Induction by cold exposure in brown adipose tissues.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000160785, Expressed in amniotic fluid and 241 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q96H78, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q96H78, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000160785, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		115028, 7 interactors

Protein interaction database and analysis system

More...IntActi		Q96H78, 3 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000407560

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q96H78, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati18 – 100Solcar 1PROSITE-ProRule annotationAdd BLAST83
Repeati107 – 210Solcar 2PROSITE-ProRule annotationAdd BLAST104
Repeati220 – 302Solcar 3PROSITE-ProRule annotationAdd BLAST83

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the mitochondrial carrier (TC 2.A.29) family. [View classification]Sequence analysis

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0765, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000155399

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_015166_3_3_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q96H78

Identification of Orthologs from Complete Genome Data

More...OMAi		ELWHEEK

Database of Orthologous Groups

More...OrthoDBi		1102784at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q96H78

TreeFam database of animal gene trees

More...TreeFami		TF354268

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.50.40.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR002067, Mit_carrier
IPR018108, Mitochondrial_sb/sol_carrier
IPR023395, Mt_carrier_dom_sf
IPR042164, SLC25A44

The PANTHER Classification System

More...PANTHERi		PTHR46314, PTHR46314, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00153, Mito_carr, 3 hits

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00926, MITOCARRIER

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF103506, SSF103506, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50920, SOLCAR, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q96H78-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEDKRNIQII EWEHLDKKKF YVFGVAMTMM IRVSVYPFTL IRTRLQVQKG 
        60         70         80         90        100
KSLYHGTFDA FIKILRADGI TGLYRGFLVN TFTLISGQCY VTTYELTRKF 
       110        120        130        140        150
VADYSQSNTV KSLVAGGSAS LVAQSITVPI DVVSQHLMMQ RKGEKMGRFQ 
       160        170        180        190        200
VRGNPEGQGV VAFGQTKDII RQILQADGLR GFYRGYVASL LTYIPNSAVW 
       210        220        230        240        250
WPFYHFYAEQ LSYLCPKECP HIVFQAVSGP LAAATASILT NPMDVIRTRV 
       260        270        280        290        300
QVEGKNSIIL TFRQLMAEEG PWGLMKGLSA RIISATPSTI VIVVGYESLK 
       310 
KLSLRPELVD SRHW
Length:314
Mass (Da):35,392
Last modified:December 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i978AE43CBDF0FBDF
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9PGQ0E9PGQ0_HUMAN
Solute carrier family 25 member 44
SLC25A44
322Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A804HJB0A0A804HJB0_HUMAN
Solute carrier family 25 member 44
SLC25A44
101Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAA32291 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti208A → AAIVFPWIP in BAA32291 (PubMed:9455484).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_05013452S → I. Corresponds to variant dbSNP:rs11576750Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AB007915 mRNA Translation: BAA32291.3 Different initiation.
AK074912 mRNA Translation: BAC11287.1
AK075002 mRNA Translation: BAC11347.1
AL135927 Genomic DNA No translation available.
BC008843 mRNA Translation: AAH08843.1
BC039854 mRNA Translation: AAH39854.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS1133.1

NCBI Reference Sequences

More...RefSeqi		NP_001273113.1, NM_001286184.1
NP_055470.1, NM_014655.3
XP_006711720.1, XM_006711657.3
XP_011508482.1, XM_011510180.1
XP_011508483.1, XM_011510181.1
XP_016858393.1, XM_017002904.1
XP_016858394.1, XM_017002905.1
XP_016858395.1, XM_017002906.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000359511; ENSP00000352497; ENSG00000160785

Database of genes from NCBI RefSeq genomes

More...GeneIDi		9673

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:9673

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000359511.5; ENSP00000352497.4; NM_014655.4; NP_055470.1

UCSC genome browser

More...UCSCi		uc001fnp.5, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB007915 mRNA Translation: BAA32291.3 Different initiation.
AK074912 mRNA Translation: BAC11287.1
AK075002 mRNA Translation: BAC11347.1
AL135927 Genomic DNA No translation available.
BC008843 mRNA Translation: AAH08843.1
BC039854 mRNA Translation: AAH39854.1
CCDSiCCDS1133.1
RefSeqiNP_001273113.1, NM_001286184.1
NP_055470.1, NM_014655.3
XP_006711720.1, XM_006711657.3
XP_011508482.1, XM_011510180.1
XP_011508483.1, XM_011510181.1
XP_016858393.1, XM_017002904.1
XP_016858394.1, XM_017002905.1
XP_016858395.1, XM_017002906.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi115028, 7 interactors
IntActiQ96H78, 3 interactors
STRINGi9606.ENSP00000407560

Protein family/group databases

TCDBi2.A.29.14.7, the mitochondrial carrier (mc) family

PTM databases

iPTMnetiQ96H78
PhosphoSitePlusiQ96H78

Genetic variation databases

BioMutaiSLC25A44
DMDMi74751902

Proteomic databases

EPDiQ96H78
jPOSTiQ96H78
MassIVEiQ96H78
MaxQBiQ96H78
PaxDbiQ96H78
PeptideAtlasiQ96H78
PRIDEiQ96H78
ProteomicsDBi76709

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		47042, 25 antibodies from 10 providers

The DNASU plasmid repository

More...DNASUi		9673

Genome annotation databases

EnsembliENST00000359511; ENSP00000352497; ENSG00000160785
GeneIDi9673
KEGGihsa:9673
MANE-SelectiENST00000359511.5; ENSP00000352497.4; NM_014655.4; NP_055470.1
UCSCiuc001fnp.5, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		9673
DisGeNETi9673

GeneCards: human genes, protein and diseases

More...GeneCardsi		SLC25A44
HGNCiHGNC:29036, SLC25A44
HPAiENSG00000160785, Low tissue specificity
MIMi610824, gene
neXtProtiNX_Q96H78
OpenTargetsiENSG00000160785
PharmGKBiPA162403705
VEuPathDBiHostDB:ENSG00000160785

Human Unidentified Gene-Encoded large proteins database

More...HUGEi		Search...

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG0765, Eukaryota
GeneTreeiENSGT00940000155399
HOGENOMiCLU_015166_3_3_1
InParanoidiQ96H78
OMAiELWHEEK
OrthoDBi1102784at2759
PhylomeDBiQ96H78
TreeFamiTF354268

Enzyme and pathway databases

PathwayCommonsiQ96H78
ReactomeiR-HSA-70895, Branched-chain amino acid catabolism
SignaLinkiQ96H78

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		9673, 6 hits in 1046 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		SLC25A44, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		9673
PharosiQ96H78, Tdark

Protein Ontology

More...PROi		PR:Q96H78
RNActiQ96H78, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000160785, Expressed in amniotic fluid and 241 other tissues
ExpressionAtlasiQ96H78, baseline and differential
GenevisibleiQ96H78, HS

Family and domain databases

Gene3Di1.50.40.10, 2 hits
InterProiView protein in InterPro
IPR002067, Mit_carrier
IPR018108, Mitochondrial_sb/sol_carrier
IPR023395, Mt_carrier_dom_sf
IPR042164, SLC25A44
PANTHERiPTHR46314, PTHR46314, 1 hit
PfamiView protein in Pfam
PF00153, Mito_carr, 3 hits
PRINTSiPR00926, MITOCARRIER
SUPFAMiSSF103506, SSF103506, 1 hit
PROSITEiView protein in PROSITE
PS50920, SOLCAR, 3 hits

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiS2544_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96H78
Secondary accession number(s): O75034
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: December 1, 2001
Last modified: February 23, 2022
This is version 155 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families
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