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UniProtKB - Q96GL9 (F163A_HUMAN)
Protein
Protein FAM163A
Gene
FAM163A
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Protein FAM163AAlternative name(s): Cebelin Neuroblastoma-derived secretory protein |
Gene namesi | Name:FAM163A Synonyms:C1orf76, NDSP |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:28274, FAM163A |
MIMi | 611727, gene |
neXtProti | NX_Q96GL9 |
VEuPathDBi | HostDB:ENSG00000143340 |
Subcellular locationi
Other locations
- Membrane Curated; Single-pass membrane protein Curated
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 6 – 26 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
MembranePathology & Biotechi
Organism-specific databases
DisGeNETi | 148753 |
OpenTargetsi | ENSG00000143340 |
PharmGKBi | PA162386944 |
Miscellaneous databases
Pharosi | Q96GL9, Tbio |
Genetic variation databases
BioMutai | FAM163A |
DMDMi | 74751887 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000280256 | 1 – 167 | Protein FAM163AAdd BLAST | 167 |
Proteomic databases
MassIVEi | Q96GL9 |
PaxDbi | Q96GL9 |
PeptideAtlasi | Q96GL9 |
PRIDEi | Q96GL9 |
TopDownProteomicsi | Q96GL9 |
PTM databases
iPTMneti | Q96GL9 |
PhosphoSitePlusi | Q96GL9 |
Expressioni
Tissue specificityi
Highly expressed in neuroblastoma compared to other tissues, suggesting that it may be used as a marker for metastasis in bone marrow.1 Publication
Gene expression databases
Bgeei | ENSG00000143340, Expressed in sperm and 103 other tissues |
Genevisiblei | Q96GL9, HS |
Organism-specific databases
HPAi | ENSG00000143340, Tissue enhanced (brain, lymphoid tissue, pituitary gland, testis) |
Interactioni
Binary interactionsi
Q96GL9
Protein-protein interaction databases
BioGRIDi | 127166, 18 interactors |
IntActi | Q96GL9, 26 interactors |
MINTi | Q96GL9 |
STRINGi | 9606.ENSP00000354891 |
Miscellaneous databases
RNActi | Q96GL9, protein |
Family & Domainsi
Sequence similaritiesi
Belongs to the FAM163 family.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | ENOG502S10V, Eukaryota |
GeneTreei | ENSGT00940000159228 |
HOGENOMi | CLU_138617_0_0_1 |
InParanoidi | Q96GL9 |
OMAi | CNACSSR |
OrthoDBi | 1417278at2759 |
PhylomeDBi | Q96GL9 |
TreeFami | TF333084 |
Family and domain databases
InterProi | View protein in InterPro IPR029379, FAM163 IPR040281, FAM163A |
PANTHERi | PTHR31914, PTHR31914, 1 hit |
Pfami | View protein in Pfam PF15069, FAM163, 1 hit |
i Sequence
Sequence statusi: Complete.
Q96GL9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTAGTVVITG GILATVILLC IIAVLCYCRL QYYCCKKSGT EVADEEEERE
60 70 80 90 100
HDLPTHPRGP TCNACSSQAL DGRGSLAPLT SEPCSQPCGV AASHCTTCSP
110 120 130 140 150
YSSPFYIRTA DMVPNGGGGE RLSFAPTYYK EGGPPSLKLA APQSYPVTWP
160
GSGREAFTNP RAISTDV
Sequence databases
Genome annotation databases
Ensembli | ENST00000341785.5; ENSP00000354891.4; ENSG00000143340.7 |
GeneIDi | 148753 |
KEGGi | hsa:148753 |
MANE-Selecti | ENST00000341785.5; ENSP00000354891.4; NM_173509.3; NP_775780.1 |
UCSCi | uc001gnj.3, human |
Similar proteinsi
Cross-referencesi
Sequence databases
3D structure databases
AlphaFoldDBi | Q96GL9 |
SMRi | Q96GL9 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 127166, 18 interactors |
IntActi | Q96GL9, 26 interactors |
MINTi | Q96GL9 |
STRINGi | 9606.ENSP00000354891 |
PTM databases
iPTMneti | Q96GL9 |
PhosphoSitePlusi | Q96GL9 |
Genetic variation databases
BioMutai | FAM163A |
DMDMi | 74751887 |
Proteomic databases
MassIVEi | Q96GL9 |
PaxDbi | Q96GL9 |
PeptideAtlasi | Q96GL9 |
PRIDEi | Q96GL9 |
TopDownProteomicsi | Q96GL9 |
Protocols and materials databases
Antibodypediai | 2490, 111 antibodies from 17 providers |
DNASUi | 148753 |
Genome annotation databases
Ensembli | ENST00000341785.5; ENSP00000354891.4; ENSG00000143340.7 |
GeneIDi | 148753 |
KEGGi | hsa:148753 |
MANE-Selecti | ENST00000341785.5; ENSP00000354891.4; NM_173509.3; NP_775780.1 |
UCSCi | uc001gnj.3, human |
Organism-specific databases
CTDi | 148753 |
DisGeNETi | 148753 |
GeneCardsi | FAM163A |
HGNCi | HGNC:28274, FAM163A |
HPAi | ENSG00000143340, Tissue enhanced (brain, lymphoid tissue, pituitary gland, testis) |
MIMi | 611727, gene |
neXtProti | NX_Q96GL9 |
OpenTargetsi | ENSG00000143340 |
PharmGKBi | PA162386944 |
VEuPathDBi | HostDB:ENSG00000143340 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG502S10V, Eukaryota |
GeneTreei | ENSGT00940000159228 |
HOGENOMi | CLU_138617_0_0_1 |
InParanoidi | Q96GL9 |
OMAi | CNACSSR |
OrthoDBi | 1417278at2759 |
PhylomeDBi | Q96GL9 |
TreeFami | TF333084 |
Enzyme and pathway databases
PathwayCommonsi | Q96GL9 |
SignaLinki | Q96GL9 |
Miscellaneous databases
BioGRID-ORCSi | 148753, 10 hits in 1061 CRISPR screens |
ChiTaRSi | FAM163A, human |
GenomeRNAii | 148753 |
Pharosi | Q96GL9, Tbio |
PROi | PR:Q96GL9 |
RNActi | Q96GL9, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000143340, Expressed in sperm and 103 other tissues |
Genevisiblei | Q96GL9, HS |
Family and domain databases
InterProi | View protein in InterPro IPR029379, FAM163 IPR040281, FAM163A |
PANTHERi | PTHR31914, PTHR31914, 1 hit |
Pfami | View protein in Pfam PF15069, FAM163, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | F163A_HUMAN | |
Accessioni | Q96GL9Primary (citable) accession number: Q96GL9 Secondary accession number(s): A8K8R7 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 20, 2007 |
Last sequence update: | December 1, 2001 | |
Last modified: | May 25, 2022 | |
This is version 128 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Uncharacterized protein families (UPF)
List of uncharacterized protein family (UPF) entries - Human chromosome 1
Human chromosome 1: entries, gene names and cross-references to MIM - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families