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Entry version 135 (16 Oct 2019)
Sequence version 1 (01 Dec 2001)
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Protein

U3 small nucleolar ribonucleoprotein protein IMP4

Gene

IMP4

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • snoRNA binding Source: GO_Central

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein
Biological processRibosome biogenesis, rRNA processing

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-6790901 rRNA modification in the nucleus and cytosol
R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
U3 small nucleolar ribonucleoprotein protein IMP4
Short name:
U3 snoRNP protein IMP4
Alternative name(s):
Brix domain-containing protein 4
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:IMP4
Synonyms:BXDC4
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:30856 IMP4

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
612981 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q96G21

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
92856

Open Targets

More...
OpenTargetsi
ENSG00000136718

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142671656

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q96G21

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
IMP4

Domain mapping of disease mutations (DMDM)

More...
DMDMi
73621060

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001202361 – 291U3 small nucleolar ribonucleoprotein protein IMP4Add BLAST291

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q96G21

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q96G21

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q96G21

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q96G21

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q96G21

PeptideAtlas

More...
PeptideAtlasi
Q96G21

PRoteomics IDEntifications database

More...
PRIDEi
Q96G21

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
76583

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q96G21

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q96G21

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q96G21

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000136718 Expressed in 222 organ(s), highest expression level in body of pancreas

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q96G21 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q96G21 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA066222
HPA066673

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of a heterotrimeric complex containing IMP3, IMP4 and MPHOSPH10.

Interacts with MPHOSPH10.

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
ZBTB7BO151564EBI-8641721,EBI-740434

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
124984, 41 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q96G21

Protein interaction database and analysis system

More...
IntActi
Q96G21, 17 interactors

Molecular INTeraction database

More...
MINTi
Q96G21

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000259239

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q96G21

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini83 – 264BrixPROSITE-ProRule annotationAdd BLAST182

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi3 – 48Arg-richAdd BLAST46

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2781 Eukaryota
COG2136 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153231

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000172063

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q96G21

KEGG Orthology (KO)

More...
KOi
K14561

Identification of Orthologs from Complete Genome Data

More...
OMAi
FFNISDV

Database of Orthologous Groups

More...
OrthoDBi
768872at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q96G21

TreeFam database of animal gene trees

More...
TreeFami
TF300016

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR007109 Brix

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04427 Brix, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00879 Brix, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50833 BRIX, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

Q96G21-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLRREARLRR EYLYRKAREE AQRSAQERKE RLRRALEENR LIPTELRREA
60 70 80 90 100
LALQGSLEFD DAGGEGVTSH VDDEYRWAGV EDPKVMITTS RDPSSRLKMF
110 120 130 140 150
AKELKLVFPG AQRMNRGRHE VGALVRACKA NGVTDLLVVH EHRGTPVGLI
160 170 180 190 200
VSHLPFGPTA YFTLCNVVMR HDIPDLGTMS EAKPHLITHG FSSRLGKRVS
210 220 230 240 250
DILRYLFPVP KDDSHRVITF ANQDDYISFR HHVYKKTDHR NVELTEVGPR
260 270 280 290
FELKLYMIRL GTLEQEATAD VEWRWHPYTN TARKRVFLST E
Length:291
Mass (Da):33,757
Last modified:December 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i460A05DFFE70C580
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H0Y714H0Y714_HUMAN
U3 small nucleolar ribonucleoprotei...
IMP4
280Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B8ZZ47B8ZZ47_HUMAN
U3 small nucleolar ribonucleoprotei...
IMP4
248Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E7ENR5E7ENR5_HUMAN
U3 small nucleolar ribonucleoprotei...
IMP4
236Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B9A008B9A008_HUMAN
U3 small nucleolar ribonucleoprotei...
IMP4
172Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8WCN0F8WCN0_HUMAN
U3 small nucleolar ribonucleoprotei...
IMP4
76Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY364245 mRNA Translation: AAQ76804.1
AK289878 mRNA Translation: BAF82567.1
AK292345 mRNA Translation: BAF85034.1
AK312808 mRNA Translation: BAG35666.1
AC132479 Genomic DNA Translation: AAY24076.1
BC010042 mRNA Translation: AAH10042.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS2160.1

NCBI Reference Sequences

More...
RefSeqi
NP_001307233.1, NM_001320304.1
NP_001307234.1, NM_001320305.1
NP_001307235.1, NM_001320306.1
NP_001307236.1, NM_001320307.1
NP_001307238.1, NM_001320309.1
NP_001307239.1, NM_001320310.1
NP_001307240.1, NM_001320311.1
NP_219484.1, NM_033416.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000259239; ENSP00000259239; ENSG00000136718

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
92856

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:92856

UCSC genome browser

More...
UCSCi
uc002tra.2 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY364245 mRNA Translation: AAQ76804.1
AK289878 mRNA Translation: BAF82567.1
AK292345 mRNA Translation: BAF85034.1
AK312808 mRNA Translation: BAG35666.1
AC132479 Genomic DNA Translation: AAY24076.1
BC010042 mRNA Translation: AAH10042.1
CCDSiCCDS2160.1
RefSeqiNP_001307233.1, NM_001320304.1
NP_001307234.1, NM_001320305.1
NP_001307235.1, NM_001320306.1
NP_001307236.1, NM_001320307.1
NP_001307238.1, NM_001320309.1
NP_001307239.1, NM_001320310.1
NP_001307240.1, NM_001320311.1
NP_219484.1, NM_033416.2

3D structure databases

SMRiQ96G21
ModBaseiSearch...

Protein-protein interaction databases

BioGridi124984, 41 interactors
CORUMiQ96G21
IntActiQ96G21, 17 interactors
MINTiQ96G21
STRINGi9606.ENSP00000259239

PTM databases

iPTMnetiQ96G21
PhosphoSitePlusiQ96G21
SwissPalmiQ96G21

Polymorphism and mutation databases

BioMutaiIMP4
DMDMi73621060

Proteomic databases

EPDiQ96G21
jPOSTiQ96G21
MassIVEiQ96G21
MaxQBiQ96G21
PaxDbiQ96G21
PeptideAtlasiQ96G21
PRIDEiQ96G21
ProteomicsDBi76583

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
92856

Genome annotation databases

EnsembliENST00000259239; ENSP00000259239; ENSG00000136718
GeneIDi92856
KEGGihsa:92856
UCSCiuc002tra.2 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
92856
DisGeNETi92856

GeneCards: human genes, protein and diseases

More...
GeneCardsi
IMP4
HGNCiHGNC:30856 IMP4
HPAiHPA066222
HPA066673
MIMi612981 gene
neXtProtiNX_Q96G21
OpenTargetsiENSG00000136718
PharmGKBiPA142671656

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG2781 Eukaryota
COG2136 LUCA
GeneTreeiENSGT00940000153231
HOGENOMiHOG000172063
InParanoidiQ96G21
KOiK14561
OMAiFFNISDV
OrthoDBi768872at2759
PhylomeDBiQ96G21
TreeFamiTF300016

Enzyme and pathway databases

ReactomeiR-HSA-6790901 rRNA modification in the nucleus and cytosol
R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
IMP4 human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
IMP4

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
92856
PharosiQ96G21

Protein Ontology

More...
PROi
PR:Q96G21

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000136718 Expressed in 222 organ(s), highest expression level in body of pancreas
ExpressionAtlasiQ96G21 baseline and differential
GenevisibleiQ96G21 HS

Family and domain databases

InterProiView protein in InterPro
IPR007109 Brix
PfamiView protein in Pfam
PF04427 Brix, 1 hit
SMARTiView protein in SMART
SM00879 Brix, 1 hit
PROSITEiView protein in PROSITE
PS50833 BRIX, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiIMP4_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96G21
Secondary accession number(s): Q3ZTT3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 16, 2005
Last sequence update: December 1, 2001
Last modified: October 16, 2019
This is version 135 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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