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Protein

WD repeat-containing protein 89

Gene

WDR89

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Enzyme and pathway databases

SignaLinkiQ96FK6

Names & Taxonomyi

Protein namesi
Recommended name:
WD repeat-containing protein 89
Gene namesi
Name:WDR89
Synonyms:C14orf150
ORF Names:MSTP050
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 14

Organism-specific databases

EuPathDBiHostDB:ENSG00000140006.11
HGNCiHGNC:20489 WDR89
neXtProtiNX_Q96FK6

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000140006
PharmGKBiPA134871067

Polymorphism and mutation databases

BioMutaiWDR89
DMDMi74762654

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002540361 – 387WD repeat-containing protein 89Add BLAST387

Proteomic databases

EPDiQ96FK6
MaxQBiQ96FK6
PaxDbiQ96FK6
PeptideAtlasiQ96FK6
PRIDEiQ96FK6
ProteomicsDBi76537

PTM databases

iPTMnetiQ96FK6
PhosphoSitePlusiQ96FK6

Expressioni

Gene expression databases

BgeeiENSG00000140006
CleanExiHS_WDR89
ExpressionAtlasiQ96FK6 baseline and differential
GenevisibleiQ96FK6 HS

Organism-specific databases

HPAiHPA000813

Interactioni

Protein-protein interaction databases

BioGridi125208, 15 interactors
IntActiQ96FK6, 5 interactors
STRINGi9606.ENSP00000267522

Structurei

3D structure databases

ProteinModelPortaliQ96FK6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati21 – 65WD 1Add BLAST45
Repeati68 – 107WD 2Add BLAST40
Repeati112 – 156WD 3Add BLAST45
Repeati168 – 208WD 4Add BLAST41
Repeati214 – 254WD 5Add BLAST41
Repeati319 – 358WD 6Add BLAST40

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

eggNOGiKOG1188 Eukaryota
ENOG410ZUMD LUCA
GeneTreeiENSGT00390000006996
HOGENOMiHOG000126822
HOVERGENiHBG055747
InParanoidiQ96FK6
OMAiRIHLMNC
OrthoDBiEOG091G08B1
PhylomeDBiQ96FK6
TreeFamiTF324390

Family and domain databases

Gene3Di2.130.10.10, 2 hits
InterProiView protein in InterPro
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
IPR039328 WDR89
PANTHERiPTHR22889 PTHR22889, 1 hit
PfamiView protein in Pfam
PF00400 WD40, 3 hits
SMARTiView protein in SMART
SM00320 WD40, 5 hits
SUPFAMiSSF50978 SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS50082 WD_REPEATS_2, 3 hits
PS50294 WD_REPEATS_REGION, 3 hits

Sequencei

Sequence statusi: Complete.

Q96FK6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKIEEQFAN LHIVKCSLGT KEPTYLLGID TSKTVQAGKE NLVAVLCSNG
60 70 80 90 100
SIRIYDKERL NVLREFSGYP GLLNGVRFAN SCDSVYSACT DGTVKCWDAR
110 120 130 140 150
VAREKPVQLF KGYPSNIFIS FDINCNDHII CAGTEKVDDD ALLVFWDARM
160 170 180 190 200
NSQNLSTTKD SLGAYSETHS DDVTQVRFHP SNPNMVVSGS SDGLVNVFDI
210 220 230 240 250
NIDNEEDALV TTCNSISSVS CIGWSGKGYK QIYCMTHDEG FYWWDLNHLD
260 270 280 290 300
TDEPVTRLNI QDVREVVNMK EDALDYLIGG LYHEKTDTLH VIGGTNKGRI
310 320 330 340 350
HLMNCSMSGL THVTSLQGGH AATVRSFCWN VQDDSLLTGG EDAQLLLWKP
360 370 380
GAIEKTFTKK ESMKIASSVH QRVRVHSNDS YKRRKKQ
Length:387
Mass (Da):43,215
Last modified:December 1, 2001 - v1
Checksum:iC0F35E0066643800
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF115513 mRNA Translation: AAO06950.1
BX248008 mRNA Translation: CAD62336.1
AK095324 mRNA Translation: BAC04530.1
BC010698 mRNA Translation: AAH10698.1
CCDSiCCDS9759.1
RefSeqiNP_001008726.1, NM_001008726.2
NP_001245201.1, NM_001258272.1
NP_542397.1, NM_080666.3
XP_011534687.1, XM_011536385.2
UniGeneiHs.655666
Hs.741323

Genome annotation databases

EnsembliENST00000267522; ENSP00000267522; ENSG00000140006
ENST00000394942; ENSP00000378399; ENSG00000140006
ENST00000620954; ENSP00000480112; ENSG00000140006
GeneIDi112840
KEGGihsa:112840
UCSCiuc031qox.2 human

Similar proteinsi

Entry informationi

Entry nameiWDR89_HUMAN
AccessioniPrimary (citable) accession number: Q96FK6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: December 1, 2001
Last modified: July 18, 2018
This is version 133 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 14
    Human chromosome 14: entries, gene names and cross-references to MIM

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