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Entry version 100 (08 May 2019)
Sequence version 1 (01 Dec 2001)
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Protein

ZBED6 C-terminal-like protein

Gene

ZBED6CL

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Miscellaneous

Similar to the C-terminus of ZBED6, but lacks BED domains, and therefore is probably not involved in transcriptional regulation. Encoded by a DNA transposon located in the 5'-untranslated region (5'-UTR) of LLRC61.

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
ZBED6 C-terminal-like protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZBED6CL
Synonyms:C7orf29
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Human Gene Nomenclature Database

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HGNCi
HGNC:21720 ZBED6CL

Online Mendelian Inheritance in Man (OMIM)

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MIMi
615252 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q96FA7

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

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OpenTargetsi
ENSG00000188707

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134942566

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZBED6CL

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000895861 – 236ZBED6 C-terminal-like proteinAdd BLAST236

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
Q96FA7

PeptideAtlas

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PeptideAtlasi
Q96FA7

PRoteomics IDEntifications database

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PRIDEi
Q96FA7

ProteomicsDB human proteome resource

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ProteomicsDBi
76506

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

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iPTMneti
Q96FA7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

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PhosphoSitePlusi
Q96FA7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSG00000188707 Expressed in 142 organ(s), highest expression level in left adrenal gland cortex

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q96FA7 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

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Genevisiblei
Q96FA7 HS

Organism-specific databases

Human Protein Atlas

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HPAi
HPA019724
HPA055805

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
125259, 4 interactors

Protein interaction database and analysis system

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IntActi
Q96FA7, 1 interactor

STRING: functional protein association networks

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STRINGi
9606.ENSP00000343242

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG410JB12 Eukaryota
ENOG41119N3 LUCA

Ensembl GeneTree

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GeneTreei
ENSGT00510000050353

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

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HOGENOMi
HOG000111588

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
Q96FA7

Identification of Orthologs from Complete Genome Data

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OMAi
NHLASVI

Database of Orthologous Groups

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OrthoDBi
1187394at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q96FA7

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q96FA7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVVREASAAQ ASLSQVLPQL RYLHIFLEQV HTHFQEQSVG ERGAAIQLAE
60 70 80 90 100
GLARQLCTDC QLNKLFYREE FVLATLLDPC FKGKIEAILP WGPTDIDHWK
110 120 130 140 150
QVLVYKVKEI RVSEYSLNSP SPLQSPRGLC VDPTRVAKSS GVEGRSQGEP
160 170 180 190 200
LQSSSHSGAF LLAQREKGLL ESMGLLASER SGGSLSTKSH WASIIVKKYL
210 220 230
WENETVGAQD DPLAYWEKKR EAWPPSICLT PHRSLL
Length:236
Mass (Da):26,352
Last modified:December 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i76769A693BC30AA4
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AC005586 Genomic DNA Translation: AAP21891.1
BC011406 mRNA Translation: AAH11406.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS5900.1

NCBI Reference Sequences

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RefSeqi
NP_612443.1, NM_138434.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000343855; ENSP00000343242; ENSG00000188707

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
113763

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:113763

UCSC genome browser

More...
UCSCi
uc003wgy.5 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005586 Genomic DNA Translation: AAP21891.1
BC011406 mRNA Translation: AAH11406.1
CCDSiCCDS5900.1
RefSeqiNP_612443.1, NM_138434.2

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi125259, 4 interactors
IntActiQ96FA7, 1 interactor
STRINGi9606.ENSP00000343242

PTM databases

iPTMnetiQ96FA7
PhosphoSitePlusiQ96FA7

Polymorphism and mutation databases

BioMutaiZBED6CL

Proteomic databases

PaxDbiQ96FA7
PeptideAtlasiQ96FA7
PRIDEiQ96FA7
ProteomicsDBi76506

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
113763
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000343855; ENSP00000343242; ENSG00000188707
GeneIDi113763
KEGGihsa:113763
UCSCiuc003wgy.5 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
113763

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZBED6CL
HGNCiHGNC:21720 ZBED6CL
HPAiHPA019724
HPA055805
MIMi615252 gene
neXtProtiNX_Q96FA7
OpenTargetsiENSG00000188707
PharmGKBiPA134942566

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410JB12 Eukaryota
ENOG41119N3 LUCA
GeneTreeiENSGT00510000050353
HOGENOMiHOG000111588
InParanoidiQ96FA7
OMAiNHLASVI
OrthoDBi1187394at2759
PhylomeDBiQ96FA7

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
113763

Protein Ontology

More...
PROi
PR:Q96FA7

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000188707 Expressed in 142 organ(s), highest expression level in left adrenal gland cortex
ExpressionAtlasiQ96FA7 baseline and differential
GenevisibleiQ96FA7 HS

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZB6CL_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96FA7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: December 1, 2001
Last modified: May 8, 2019
This is version 100 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  2. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
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