Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Coiled-coil domain-containing protein 97

Gene

CCDC97

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Coiled-coil domain-containing protein 97
Gene namesi
Name:CCDC97
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

EuPathDBiHostDB:ENSG00000142039.3
HGNCiHGNC:28289 CCDC97
neXtProtiNX_Q96F63

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

DisGeNETi90324
OpenTargetsiENSG00000142039
PharmGKBiPA144596464

Polymorphism and mutation databases

BioMutaiCCDC97
DMDMi74731660

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002860961 – 343Coiled-coil domain-containing protein 97Add BLAST343

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei1N-acetylmethionineCombined sources1
Modified residuei47PhosphothreonineCombined sources1
Modified residuei275PhosphoserineCombined sources1
Modified residuei337PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

EPDiQ96F63
MaxQBiQ96F63
PaxDbiQ96F63
PeptideAtlasiQ96F63
PRIDEiQ96F63
ProteomicsDBi76498

PTM databases

iPTMnetiQ96F63
PhosphoSitePlusiQ96F63

Expressioni

Gene expression databases

BgeeiENSG00000142039 Expressed in 192 organ(s), highest expression level in testis
CleanExiHS_CCDC97
ExpressionAtlasiQ96F63 baseline and differential
GenevisibleiQ96F63 HS

Organism-specific databases

HPAiHPA043320
HPA043572

Interactioni

Protein-protein interaction databases

BioGridi124693, 26 interactors
IntActiQ96F63, 4 interactors
STRINGi9606.ENSP00000269967

Structurei

3D structure databases

ProteinModelPortaliQ96F63
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili224 – 262Sequence analysisAdd BLAST39

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiKOG3044 Eukaryota
ENOG4111QQ2 LUCA
GeneTreeiENSGT00390000015495
HOGENOMiHOG000246995
HOVERGENiHBG059629
InParanoidiQ96F63
OMAiMMQRAPD
OrthoDBiEOG091G0MCZ
PhylomeDBiQ96F63
TreeFamiTF316152

Family and domain databases

InterProiView protein in InterPro
IPR018613 DUF2052_coiled-coil
PANTHERiPTHR31840 PTHR31840, 1 hit
PfamiView protein in Pfam
PF09747 DUF2052, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q96F63-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEAVATATAA KEPDKGCIEP GPGHWGELSR TPVPSKPQDK VEAAEATPVA
60 70 80 90 100
LDSDTSGAEN AAVSAMLHAV AASRLPVCSQ QQGEPDLTEH EKVAILAQLY
110 120 130 140 150
HEKPLVFLER FRTGLREEHL ACFGHVRGDH RADFYCAEVA RQGTARPRTL
160 170 180 190 200
RTRLRNRRYA ALRELIQGGE YFSDEQMRFR APLLYEQYIG QYLTQEELSA
210 220 230 240 250
RTPTHQPPKP GSPGRPACPL SNLLLQSYEE RELQQRLLQQ QEEEEACLEE
260 270 280 290 300
EEEEEDSDEE DQRSGKDSEA WVPDSEERLI LREEFTSRMH QRFLDGKDGD
310 320 330 340
FDYSTVDDNP DFDNLDIVAR DEEERYFDEE EPEDAPSPEL DGD
Length:343
Mass (Da):38,947
Last modified:December 1, 2001 - v1
Checksum:i5153E473FF0D2069
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M0QXS4M0QXS4_HUMAN
Coiled-coil domain-containing prote...
CCDC97
154Annotation score:
M0QZY6M0QZY6_HUMAN
Coiled-coil domain-containing prote...
CCDC97
16Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC007575 mRNA Translation: AAH07575.1
BC011577 mRNA Translation: AAH11577.1
AL833726 mRNA Translation: CAH56251.1
CCDSiCCDS12578.1
RefSeqiNP_443080.1, NM_052848.2
UniGeneiHs.437497

Genome annotation databases

EnsembliENST00000269967; ENSP00000269967; ENSG00000142039
GeneIDi90324
KEGGihsa:90324
UCSCiuc002oqg.3 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC007575 mRNA Translation: AAH07575.1
BC011577 mRNA Translation: AAH11577.1
AL833726 mRNA Translation: CAH56251.1
CCDSiCCDS12578.1
RefSeqiNP_443080.1, NM_052848.2
UniGeneiHs.437497

3D structure databases

ProteinModelPortaliQ96F63
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi124693, 26 interactors
IntActiQ96F63, 4 interactors
STRINGi9606.ENSP00000269967

PTM databases

iPTMnetiQ96F63
PhosphoSitePlusiQ96F63

Polymorphism and mutation databases

BioMutaiCCDC97
DMDMi74731660

Proteomic databases

EPDiQ96F63
MaxQBiQ96F63
PaxDbiQ96F63
PeptideAtlasiQ96F63
PRIDEiQ96F63
ProteomicsDBi76498

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000269967; ENSP00000269967; ENSG00000142039
GeneIDi90324
KEGGihsa:90324
UCSCiuc002oqg.3 human

Organism-specific databases

CTDi90324
DisGeNETi90324
EuPathDBiHostDB:ENSG00000142039.3
GeneCardsiCCDC97
HGNCiHGNC:28289 CCDC97
HPAiHPA043320
HPA043572
neXtProtiNX_Q96F63
OpenTargetsiENSG00000142039
PharmGKBiPA144596464
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3044 Eukaryota
ENOG4111QQ2 LUCA
GeneTreeiENSGT00390000015495
HOGENOMiHOG000246995
HOVERGENiHBG059629
InParanoidiQ96F63
OMAiMMQRAPD
OrthoDBiEOG091G0MCZ
PhylomeDBiQ96F63
TreeFamiTF316152

Miscellaneous databases

ChiTaRSiCCDC97 human
GenomeRNAii90324
PROiPR:Q96F63

Gene expression databases

BgeeiENSG00000142039 Expressed in 192 organ(s), highest expression level in testis
CleanExiHS_CCDC97
ExpressionAtlasiQ96F63 baseline and differential
GenevisibleiQ96F63 HS

Family and domain databases

InterProiView protein in InterPro
IPR018613 DUF2052_coiled-coil
PANTHERiPTHR31840 PTHR31840, 1 hit
PfamiView protein in Pfam
PF09747 DUF2052, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiCCD97_HUMAN
AccessioniPrimary (citable) accession number: Q96F63
Secondary accession number(s): Q658N6, Q96IF3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: December 1, 2001
Last modified: September 12, 2018
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again