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Protein

Coiled-coil domain-containing protein 51

Gene

CCDC51

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Coiled-coil domain-containing protein 51
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CCDC51
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000164051.13

Human Gene Nomenclature Database

More...
HGNCi
HGNC:25714 CCDC51

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q96ER9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei202 – 222HelicalSequence analysisAdd BLAST21
Transmembranei387 – 407HelicalSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000164051

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142672167

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
CCDC51

Domain mapping of disease mutations (DMDM)

More...
DMDMi
152032342

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002888681 – 411Coiled-coil domain-containing protein 51Add BLAST411

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei70PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q96ER9

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q96ER9

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q96ER9

PeptideAtlas

More...
PeptideAtlasi
Q96ER9

PRoteomics IDEntifications database

More...
PRIDEi
Q96ER9

ProteomicsDB human proteome resource

More...
ProteomicsDBi
76443
76444 [Q96ER9-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q96ER9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q96ER9

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q96ER9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000164051 Expressed in 197 organ(s), highest expression level in pigmented layer of retina

CleanEx database of gene expression profiles

More...
CleanExi
HS_CCDC51

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q96ER9 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q96ER9 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA010980
HPA011408

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
122831, 47 interactors

Protein interaction database and analysis system

More...
IntActi
Q96ER9, 5 interactors

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q96ER9

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q96ER9

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili111 – 173Sequence analysisAdd BLAST63

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IHSU Eukaryota
ENOG4111WD5 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000001709

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000111419

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG100936

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q96ER9

Identification of Orthologs from Complete Genome Data

More...
OMAi
PVFAMQH

Database of Orthologous Groups

More...
OrthoDBi
EOG091G0CXE

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q96ER9

TreeFam database of animal gene trees

More...
TreeFami
TF318449

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR037660 CCDC51

The PANTHER Classification System

More...
PANTHERi
PTHR28624 PTHR28624, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q96ER9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MMGRSPGFAM QHIVGVPHVL VRRGLLGRDL FMTRTLCSPG PSQPGEKRPE
60 70 80 90 100
EVALGLHHRL PALGRALGHS IQQRATSTAK TWWDRYEEFV GLNEVREAQG
110 120 130 140 150
KVTEAEKVFM VARGLVREAR EDLEVHQAKL KEVRDRLDRV SREDSQYLEL
160 170 180 190 200
ATLEHRMLQE EKRLRTAYLR AEDSEREKFS LFSAAVRESH EKERTRAERT
210 220 230 240 250
KNWSLIGSVL GALIGVAGST YVNRVRLQEL KALLLEAQKG PVSLQEAIRE
260 270 280 290 300
QASSYSRQQR DLHNLMVDLR GLVHAAGPGQ DSGSQAGSPP TRDRDVDVLS
310 320 330 340 350
AALKEQLSHS RQVHSCLEGL REQLDGLEKT CSQMAGVVQL VKSAAHPGLV
360 370 380 390 400
EPADGAMPSF LLEQGSMILA LSDTEQRLEA QVNRNTIYST LVTCVTFVAT
410
LPVLYMLFKA S
Length:411
Mass (Da):45,811
Last modified:May 29, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD99F1D8AF9EB8C04
GO
Isoform 2 (identifier: Q96ER9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-109: Missing.

Note: No experimental confirmation available.
Show »
Length:302
Mass (Da):33,657
Checksum:i12C2189386744A44
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
C9JSW8C9JSW8_HUMAN
Coiled-coil domain-containing prote...
CCDC51
159Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JPZ8C9JPZ8_HUMAN
Coiled-coil domain-containing prote...
CCDC51
62Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH11993 differs from that shown. Reason: Erroneous initiation.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_032515360F → S. Corresponds to variant dbSNP:rs7618609Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0258001 – 109Missing in isoform 2. 1 PublicationAdd BLAST109

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK022498 mRNA Translation: BAB14060.1
BC011993 mRNA Translation: AAH11993.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS2766.2 [Q96ER9-1]
CCDS58830.1 [Q96ER9-2]

NCBI Reference Sequences

More...
RefSeqi
NP_001243893.1, NM_001256964.1 [Q96ER9-1]
NP_001243894.1, NM_001256965.2 [Q96ER9-2]
NP_001243895.1, NM_001256966.2 [Q96ER9-2]
NP_001243896.1, NM_001256967.2 [Q96ER9-2]
NP_001243897.1, NM_001256968.2 [Q96ER9-2]
NP_001243898.1, NM_001256969.2 [Q96ER9-2]
NP_078937.3, NM_024661.4 [Q96ER9-1]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.187657
Hs.740720

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000395694; ENSP00000379047; ENSG00000164051 [Q96ER9-1]
ENST00000412398; ENSP00000401194; ENSG00000164051 [Q96ER9-2]
ENST00000442740; ENSP00000392898; ENSG00000164051 [Q96ER9-2]
ENST00000447018; ENSP00000412300; ENSG00000164051 [Q96ER9-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
79714

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:79714

UCSC genome browser

More...
UCSCi
uc003ctd.3 human [Q96ER9-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK022498 mRNA Translation: BAB14060.1
BC011993 mRNA Translation: AAH11993.1 Different initiation.
CCDSiCCDS2766.2 [Q96ER9-1]
CCDS58830.1 [Q96ER9-2]
RefSeqiNP_001243893.1, NM_001256964.1 [Q96ER9-1]
NP_001243894.1, NM_001256965.2 [Q96ER9-2]
NP_001243895.1, NM_001256966.2 [Q96ER9-2]
NP_001243896.1, NM_001256967.2 [Q96ER9-2]
NP_001243897.1, NM_001256968.2 [Q96ER9-2]
NP_001243898.1, NM_001256969.2 [Q96ER9-2]
NP_078937.3, NM_024661.4 [Q96ER9-1]
UniGeneiHs.187657
Hs.740720

3D structure databases

ProteinModelPortaliQ96ER9
SMRiQ96ER9
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi122831, 47 interactors
IntActiQ96ER9, 5 interactors

PTM databases

iPTMnetiQ96ER9
PhosphoSitePlusiQ96ER9
SwissPalmiQ96ER9

Polymorphism and mutation databases

BioMutaiCCDC51
DMDMi152032342

Proteomic databases

EPDiQ96ER9
MaxQBiQ96ER9
PaxDbiQ96ER9
PeptideAtlasiQ96ER9
PRIDEiQ96ER9
ProteomicsDBi76443
76444 [Q96ER9-2]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
79714
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000395694; ENSP00000379047; ENSG00000164051 [Q96ER9-1]
ENST00000412398; ENSP00000401194; ENSG00000164051 [Q96ER9-2]
ENST00000442740; ENSP00000392898; ENSG00000164051 [Q96ER9-2]
ENST00000447018; ENSP00000412300; ENSG00000164051 [Q96ER9-2]
GeneIDi79714
KEGGihsa:79714
UCSCiuc003ctd.3 human [Q96ER9-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
79714
EuPathDBiHostDB:ENSG00000164051.13

GeneCards: human genes, protein and diseases

More...
GeneCardsi
CCDC51

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0003284
HGNCiHGNC:25714 CCDC51
HPAiHPA010980
HPA011408
neXtProtiNX_Q96ER9
OpenTargetsiENSG00000164051
PharmGKBiPA142672167

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IHSU Eukaryota
ENOG4111WD5 LUCA
GeneTreeiENSGT00390000001709
HOGENOMiHOG000111419
HOVERGENiHBG100936
InParanoidiQ96ER9
OMAiPVFAMQH
OrthoDBiEOG091G0CXE
PhylomeDBiQ96ER9
TreeFamiTF318449

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
79714

Protein Ontology

More...
PROi
PR:Q96ER9

Gene expression databases

BgeeiENSG00000164051 Expressed in 197 organ(s), highest expression level in pigmented layer of retina
CleanExiHS_CCDC51
ExpressionAtlasiQ96ER9 baseline and differential
GenevisibleiQ96ER9 HS

Family and domain databases

InterProiView protein in InterPro
IPR037660 CCDC51
PANTHERiPTHR28624 PTHR28624, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCCD51_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96ER9
Secondary accession number(s): Q9HA01
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: May 29, 2007
Last modified: November 7, 2018
This is version 110 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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