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Entry version 132 (08 May 2019)
Sequence version 1 (01 Dec 2001)
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Protein

PHD finger protein 21B

Gene

PHF21B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri352 – 399PHD-typePROSITE-ProRule annotationAdd BLAST48

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
PHD finger protein 21B
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PHF21B
Synonyms:KIAA1661
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 22

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:25161 PHF21B

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
616727 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q96EK2

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
112885

Open Targets

More...
OpenTargetsi
ENSG00000056487

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134872136

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
PHF21B

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74731574

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002267691 – 531PHD finger protein 21BAdd BLAST531

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q96EK2

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q96EK2

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q96EK2

PeptideAtlas

More...
PeptideAtlasi
Q96EK2

PRoteomics IDEntifications database

More...
PRIDEi
Q96EK2

ProteomicsDB human proteome resource

More...
ProteomicsDBi
76413
76414 [Q96EK2-3]
76415 [Q96EK2-4]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q96EK2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q96EK2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000056487 Expressed in 101 organ(s), highest expression level in adenohypophysis

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q96EK2 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q96EK2 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA053834

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
125214, 4 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q96EK2

Protein interaction database and analysis system

More...
IntActi
Q96EK2, 2 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000324403

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q96EK2

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili423 – 465Sequence analysisAdd BLAST43

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri352 – 399PHD-typePROSITE-ProRule annotationAdd BLAST48

Keywords - Domaini

Coiled coil, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IRE8 Eukaryota
ENOG4111F4Y LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000161105

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000231466

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q96EK2

Identification of Orthologs from Complete Genome Data

More...
OMAi
VWVCPKC

Database of Orthologous Groups

More...
OrthoDBi
1185408at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q96EK2

TreeFam database of animal gene trees

More...
TreeFami
TF331518

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00628 PHD, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00249 PHD, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57903 SSF57903, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50016 ZF_PHD_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q96EK2-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MELQSRPEAL AVELARHQNG DLKKQLHERQ PRIAALSDKQ ALGTITAVPV
60 70 80 90 100
TGPQVSSLQR LAGQGAAVLP QVRPKTLIPD SLPVAPGRDR PPKQPPTFQK
110 120 130 140 150
ATVVSVKNPS PALPTANNTV SHVPAPGSQP QALAEPAALA SPLSSAGVAY
160 170 180 190 200
AIISTSPSNA AAMAPSTAVS VVSDSIKVQP LLISADNKPP PRLLSSPHPA
210 220 230 240 250
THHCPLHPSS LPLTPPSPSL SPSPLHGIFQ VIIIQPQVQT QPESTAESRP
260 270 280 290 300
PTEEPSQGAQ ATKKKKEDRP PTQENPEKIA FMVALGLVTT EHLEEIQSKR
310 320 330 340 350
QERKRRSTAN PAYSGLLETE RKRLASNYLN NPLFLTARAN EDPCWKNEIT
360 370 380 390 400
HDEHCAACKR GANLQPCGTC PGAYHLSCLE PPLKTAPKGV WVCPRCQQKA
410 420 430 440 450
LKKDEGVPWT GMLAIVHSYV THKTVKEEEK QKLLQRGSEL QNEHQQLEER
460 470 480 490 500
DRRLASAVQK CLELKTSLLA RQRGTQSSLD RLRALLRLIQ GEQLLQVTMT
510 520 530
TTSPAPLLAG PWTKPSVAAT HPTVQHPQGH N
Length:531
Mass (Da):57,455
Last modified:December 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5EFBAAEC1D952941
GO
Isoform 2 (identifier: Q96EK2-3) [UniParc]FASTAAdd to basket
Also known as: 3

The sequence of this isoform differs from the canonical sequence as follows:
     189-230: Missing.

Show »
Length:489
Mass (Da):53,040
Checksum:i71AF064E6C2CA34A
GO
Isoform 3 (identifier: Q96EK2-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-17: MELQSRPEALAVELARH → MRRQP
     189-230: Missing.

Note: No experimental confirmation available.
Show »
Length:477
Mass (Da):51,776
Checksum:i69B5D050360F14D6
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B1AHC5B1AHC5_HUMAN
PHD finger protein 21B
PHF21B hCG_1989577
327Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B1AHC6B1AHC6_HUMAN
PHD finger protein 21B
PHF21B
137Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B0QYW2B0QYW2_HUMAN
PHD finger protein 21B
PHF21B
191Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_051601127G → S. Corresponds to variant dbSNP:rs8135982Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0431491 – 17MELQS…ELARH → MRRQP in isoform 3. 1 PublicationAdd BLAST17
Alternative sequenceiVSP_017456189 – 230Missing in isoform 2 and isoform 3. 2 PublicationsAdd BLAST42

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CR456448 mRNA Translation: CAG30334.1
AK092243 mRNA Translation: BAG52506.1
AK297317 mRNA Translation: BAH12544.1
AL049760 Genomic DNA No translation available.
Z83838 Genomic DNA No translation available.
CH471138 Genomic DNA Translation: EAW73366.1
BC012187 mRNA Translation: AAH12187.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS14061.1 [Q96EK2-1]
CCDS46727.1 [Q96EK2-3]
CCDS56234.1 [Q96EK2-4]

NCBI Reference Sequences

More...
RefSeqi
NP_001129334.1, NM_001135862.2 [Q96EK2-3]
NP_001229379.1, NM_001242450.1 [Q96EK2-4]
NP_001271225.1, NM_001284296.1
NP_612424.1, NM_138415.4 [Q96EK2-1]
XP_006724185.1, XM_006724122.1 [Q96EK2-3]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000313237; ENSP00000324403; ENSG00000056487 [Q96EK2-1]
ENST00000396103; ENSP00000379410; ENSG00000056487 [Q96EK2-4]
ENST00000629843; ENSP00000487086; ENSG00000056487 [Q96EK2-3]

Database of genes from NCBI RefSeq genomes

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GeneIDi
112885

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:112885

UCSC genome browser

More...
UCSCi
uc003bfn.4 human [Q96EK2-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR456448 mRNA Translation: CAG30334.1
AK092243 mRNA Translation: BAG52506.1
AK297317 mRNA Translation: BAH12544.1
AL049760 Genomic DNA No translation available.
Z83838 Genomic DNA No translation available.
CH471138 Genomic DNA Translation: EAW73366.1
BC012187 mRNA Translation: AAH12187.1
CCDSiCCDS14061.1 [Q96EK2-1]
CCDS46727.1 [Q96EK2-3]
CCDS56234.1 [Q96EK2-4]
RefSeqiNP_001129334.1, NM_001135862.2 [Q96EK2-3]
NP_001229379.1, NM_001242450.1 [Q96EK2-4]
NP_001271225.1, NM_001284296.1
NP_612424.1, NM_138415.4 [Q96EK2-1]
XP_006724185.1, XM_006724122.1 [Q96EK2-3]

3D structure databases

SMRiQ96EK2
ModBaseiSearch...

Protein-protein interaction databases

BioGridi125214, 4 interactors
CORUMiQ96EK2
IntActiQ96EK2, 2 interactors
STRINGi9606.ENSP00000324403

PTM databases

iPTMnetiQ96EK2
PhosphoSitePlusiQ96EK2

Polymorphism and mutation databases

BioMutaiPHF21B
DMDMi74731574

Proteomic databases

jPOSTiQ96EK2
MaxQBiQ96EK2
PaxDbiQ96EK2
PeptideAtlasiQ96EK2
PRIDEiQ96EK2
ProteomicsDBi76413
76414 [Q96EK2-3]
76415 [Q96EK2-4]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
112885
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000313237; ENSP00000324403; ENSG00000056487 [Q96EK2-1]
ENST00000396103; ENSP00000379410; ENSG00000056487 [Q96EK2-4]
ENST00000629843; ENSP00000487086; ENSG00000056487 [Q96EK2-3]
GeneIDi112885
KEGGihsa:112885
UCSCiuc003bfn.4 human [Q96EK2-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
112885
DisGeNETi112885

GeneCards: human genes, protein and diseases

More...
GeneCardsi
PHF21B
HGNCiHGNC:25161 PHF21B
HPAiHPA053834
MIMi616727 gene
neXtProtiNX_Q96EK2
OpenTargetsiENSG00000056487
PharmGKBiPA134872136

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IRE8 Eukaryota
ENOG4111F4Y LUCA
GeneTreeiENSGT00940000161105
HOGENOMiHOG000231466
InParanoidiQ96EK2
OMAiVWVCPKC
OrthoDBi1185408at2759
PhylomeDBiQ96EK2
TreeFamiTF331518

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
PHF21B human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
112885

Protein Ontology

More...
PROi
PR:Q96EK2

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000056487 Expressed in 101 organ(s), highest expression level in adenohypophysis
ExpressionAtlasiQ96EK2 baseline and differential
GenevisibleiQ96EK2 HS

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF00628 PHD, 1 hit
SMARTiView protein in SMART
SM00249 PHD, 1 hit
SUPFAMiSSF57903 SSF57903, 1 hit
PROSITEiView protein in PROSITE
PS50016 ZF_PHD_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPF21B_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96EK2
Secondary accession number(s): B0QYW3
, B0QYW4, B3KRU4, B7Z4F8, Q5TFL2, Q6ICC0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 7, 2006
Last sequence update: December 1, 2001
Last modified: May 8, 2019
This is version 132 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 22
    Human chromosome 22: entries, gene names and cross-references to MIM
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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