UniProtKB - Q96EF9 (ZHX1R_HUMAN)
Protein
Zinc fingers and homeoboxes protein 1, isoform 2
Gene
ZHX1-C8orf76
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Zinc fingers and homeoboxes protein 1, isoform 2Alternative name(s): ZHX1-C8orf76 readthrough transcript protein |
Gene namesi | Name:ZHX1-C8orf76 Synonyms:C8orf76 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000259305.6 |
HGNCi | HGNC:42975, ZHX1-C8orf76 |
neXtProti | NX_Q96EF9 |
Pathology & Biotechi
Miscellaneous databases
Pharosi | Q96EF9, Tdark |
Polymorphism and mutation databases
BioMutai | ZHX1-C8orf76 |
DMDMi | 74731558 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000415939 | 1 – 292 | Zinc fingers and homeoboxes protein 1, isoform 2Add BLAST | 292 |
Proteomic databases
EPDi | Q96EF9 |
jPOSTi | Q96EF9 |
MassIVEi | Q96EF9 |
PaxDbi | Q96EF9 |
PeptideAtlasi | Q96EF9 |
PRIDEi | Q96EF9 |
ProteomicsDBi | 76404 [Q96EF9-1] |
PTM databases
iPTMneti | Q96EF9 |
Expressioni
Gene expression databases
Bgeei | ENSG00000259305, Expressed in liver and 111 other tissues |
ExpressionAtlasi | Q96EF9, baseline and differential |
Genevisiblei | Q96EF9, HS |
Organism-specific databases
HPAi | ENSG00000259305, Low tissue specificity |
Interactioni
Protein-protein interaction databases
STRINGi | 9606.ENSP00000481928 |
Miscellaneous databases
RNActi | Q96EF9, protein |
Family & Domainsi
Phylogenomic databases
eggNOGi | ENOG502QW95, Eukaryota |
GeneTreei | ENSGT00390000011435 |
HOGENOMi | CLU_044858_0_0_1 |
InParanoidi | Q96EF9 |
OrthoDBi | 113584at2759 |
TreeFami | TF332319 |
Family and domain databases
Gene3Di | 1.25.40.10, 1 hit |
InterProi | View protein in InterPro IPR041404, DUF5588 IPR011990, TPR-like_helical_dom_sf |
PANTHERi | PTHR31919, PTHR31919, 1 hit |
Pfami | View protein in Pfam PF17826, DUF5588, 1 hit |
SUPFAMi | SSF48452, SSF48452, 1 hit |
s (3+)i Sequence
Sequence statusi: Complete.
This entry describes 3 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 3 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All
Isoform 2 (identifier: Q96EF9-1) [UniParc]FASTAAdd to basket
Also known as: ZHX1-C8orf76
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MLRKLWQWFY EETESSDDVE VLTLKKFKGD LAYRRQEYQK ALQEYSSISE
60 70 80 90 100
KLSSTNFAMK RDVQEGQARC LAHLGRHMEA LEIAANLENK ATNTDHLTTV
110 120 130 140 150
LYLQLAICSS LQNLEKTIFC LQKLISLHPF NPWNWGKLAE AYLNLGPALS
160 170 180 190 200
AALASSQKQH SFTSSDKTIK SFFPHSGKDC LLCFPETLPE SSLFSVEANS
210 220 230 240 250
SNSQKNEKAL TNIQNCMAEK RETVLIETQL KACASFIRTR LLLQFTQPQQ
260 270 280 290
TSFALERNLR TQQEIEDKMK GFSFKEDTLL LIAEVSVSLG FM
Note: Based on a readthrough transcript which may produce a ZHX1-C8orf76 fusion protein.
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A0X1KG80 | A0A0X1KG80_HUMAN | Zinc fingers and homeoboxes protein... | ZHX1-C8orf76 | 140 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC068228 Genomic DNA No translation available. BC012379 mRNA Translation: AAH12379.1 |
CCDSi | CCDS56552.1 [Q96EF9-1] |
RefSeqi | NP_001191109.1, NM_001204180.1 [Q96EF9-1] |
Genome annotation databases
Ensembli | ENST00000357082; ENSP00000349593; ENSG00000259305 [Q96EF9-1] |
GeneIDi | 100533106 |
KEGGi | hsa:100533106 |
UCSCi | uc003yqd.4, human [Q96EF9-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC068228 Genomic DNA No translation available. BC012379 mRNA Translation: AAH12379.1 |
CCDSi | CCDS56552.1 [Q96EF9-1] |
RefSeqi | NP_001191109.1, NM_001204180.1 [Q96EF9-1] |
3D structure databases
SMRi | Q96EF9 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 9606.ENSP00000481928 |
PTM databases
iPTMneti | Q96EF9 |
Polymorphism and mutation databases
BioMutai | ZHX1-C8orf76 |
DMDMi | 74731558 |
Proteomic databases
EPDi | Q96EF9 |
jPOSTi | Q96EF9 |
MassIVEi | Q96EF9 |
PaxDbi | Q96EF9 |
PeptideAtlasi | Q96EF9 |
PRIDEi | Q96EF9 |
ProteomicsDBi | 76404 [Q96EF9-1] |
Protocols and materials databases
Antibodypediai | 77359, 19 antibodies |
Genome annotation databases
Ensembli | ENST00000357082; ENSP00000349593; ENSG00000259305 [Q96EF9-1] |
GeneIDi | 100533106 |
KEGGi | hsa:100533106 |
UCSCi | uc003yqd.4, human [Q96EF9-1] |
Organism-specific databases
CTDi | 100533106 |
EuPathDBi | HostDB:ENSG00000259305.6 |
GeneCardsi | ZHX1-C8orf76 |
HGNCi | HGNC:42975, ZHX1-C8orf76 |
HPAi | ENSG00000259305, Low tissue specificity |
neXtProti | NX_Q96EF9 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG502QW95, Eukaryota |
GeneTreei | ENSGT00390000011435 |
HOGENOMi | CLU_044858_0_0_1 |
InParanoidi | Q96EF9 |
OrthoDBi | 113584at2759 |
TreeFami | TF332319 |
Enzyme and pathway databases
PathwayCommonsi | Q96EF9 |
Miscellaneous databases
BioGRID-ORCSi | 100533106, 2 hits in 437 CRISPR screens |
ChiTaRSi | ZHX1-C8orf76, human |
GenomeRNAii | 100533106 |
Pharosi | Q96EF9, Tdark |
PROi | PR:Q96EF9 |
RNActi | Q96EF9, protein |
Gene expression databases
Bgeei | ENSG00000259305, Expressed in liver and 111 other tissues |
ExpressionAtlasi | Q96EF9, baseline and differential |
Genevisiblei | Q96EF9, HS |
Family and domain databases
Gene3Di | 1.25.40.10, 1 hit |
InterProi | View protein in InterPro IPR041404, DUF5588 IPR011990, TPR-like_helical_dom_sf |
PANTHERi | PTHR31919, PTHR31919, 1 hit |
Pfami | View protein in Pfam PF17826, DUF5588, 1 hit |
SUPFAMi | SSF48452, SSF48452, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | ZHX1R_HUMAN | |
Accessioni | Q96EF9Primary (citable) accession number: Q96EF9 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 21, 2012 |
Last sequence update: | December 1, 2001 | |
Last modified: | December 2, 2020 | |
This is version 112 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 8
Human chromosome 8: entries, gene names and cross-references to MIM