UniProtKB - Q96E35 (ZMY19_HUMAN)
Protein
Zinc finger MYND domain-containing protein 19
Gene
ZMYND19
Organism
Homo sapiens (Human)
Status
Functioni
May be involved as a regulatory molecule in GPR24/MCH-R1 signaling.
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 164 – 212 | MYND-typePROSITE-ProRule annotationAdd BLAST | 49 |
GO - Molecular functioni
- metal ion binding Source: UniProtKB-KW
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Recommended name: Zinc finger MYND domain-containing protein 19Alternative name(s): Melanin-concentrating hormone receptor 1-interacting zinc finger protein Short name: MCH-R1-interacting zinc finger protein |
Gene namesi | Name:ZMYND19 Synonyms:MIZIP |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000165724.5 |
HGNCi | HGNC:21146 ZMYND19 |
MIMi | 611424 gene |
neXtProti | NX_Q96E35 |
Subcellular locationi
Plasma membrane
- Cell membrane 1 Publication; Peripheral membrane protein 1 Publication
Other locations
- Cytoplasm 1 Publication
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Other locations
Keywords - Cellular componenti
Cell membrane, Cytoplasm, MembranePathology & Biotechi
Organism-specific databases
OpenTargetsi | ENSG00000165724 |
PharmGKBi | PA134878875 |
Polymorphism and mutation databases
BioMutai | ZMYND19 |
DMDMi | 46397255 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000218319 | 1 – 227 | Zinc finger MYND domain-containing protein 19Add BLAST | 227 |
Proteomic databases
EPDi | Q96E35 |
jPOSTi | Q96E35 |
MaxQBi | Q96E35 |
PaxDbi | Q96E35 |
PeptideAtlasi | Q96E35 |
PRIDEi | Q96E35 |
ProteomicsDBi | 76369 |
PTM databases
iPTMneti | Q96E35 |
PhosphoSitePlusi | Q96E35 |
Expressioni
Tissue specificityi
Expressed in brain, testis, placenta, heart, liver, skeletal muscle, kidney and stomach.1 Publication
Gene expression databases
Bgeei | ENSG00000165724 Expressed in 184 organ(s), highest expression level in right testis |
Genevisiblei | Q96E35 HS |
Organism-specific databases
HPAi | HPA020642 HPA050761 |
Interactioni
Subunit structurei
Interacts with GPR24/MCH-R1.1 Publication
Binary interactionsi
Protein-protein interaction databases
BioGridi | 125490, 60 interactors |
IntActi | Q96E35, 52 interactors |
MINTi | Q96E35 |
STRINGi | 9606.ENSP00000298585 |
Family & Domainsi
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 158 – 161 | Poly-Glu | 4 |
Zinc finger
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 164 – 212 | MYND-typePROSITE-ProRule annotationAdd BLAST | 49 |
Keywords - Domaini
Zinc-fingerPhylogenomic databases
eggNOGi | ENOG410IF0H Eukaryota ENOG410YJQA LUCA |
GeneTreei | ENSGT00390000012479 |
HOGENOMi | HOG000231532 |
HOVERGENi | HBG058268 |
InParanoidi | Q96E35 |
OMAi | CREKKRT |
OrthoDBi | 1254383at2759 |
PhylomeDBi | Q96E35 |
TreeFami | TF329209 |
Family and domain databases
InterProi | View protein in InterPro IPR003615 HNH_nuc IPR032978 ZMYND19 IPR002893 Znf_MYND |
PANTHERi | PTHR13244:SF5 PTHR13244:SF5, 1 hit |
Pfami | View protein in Pfam PF13392 HNH_3, 1 hit PF01753 zf-MYND, 1 hit |
PROSITEi | View protein in PROSITE PS01360 ZF_MYND_1, 1 hit PS50865 ZF_MYND_2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q96E35-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTDFKLGIVR LGRVAGKTKY TLIDEQDIPL VESYSFEARM EVDADGNGAK
60 70 80 90 100
IFAYAFDKNR GRGSGRLLHE LLWERHRGGV APGFQVVHLN AVTVDNRLDN
110 120 130 140 150
LQLVPWGWRP KAEETSSKQR EQSLYWLAIQ QLPTDPIEEQ FPVLNVTRYY
160 170 180 190 200
NANGDVVEEE ENSCTYYECH YPPCTVIEKQ LREFNICGRC QVARYCGSQC
210 220
QQKDWPAHKK HCRERKRPFQ HELEPER
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AJ298882 mRNA Translation: CAC16691.1 AL365502 Genomic DNA No translation available. BC012948 mRNA Translation: AAH12948.1 |
CCDSi | CCDS7048.1 |
RefSeqi | NP_612471.1, NM_138462.2 |
UniGenei | Hs.128096 |
Genome annotation databases
Ensembli | ENST00000298585; ENSP00000298585; ENSG00000165724 |
GeneIDi | 116225 |
KEGGi | hsa:116225 |
UCSCi | uc004cno.2 human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AJ298882 mRNA Translation: CAC16691.1 AL365502 Genomic DNA No translation available. BC012948 mRNA Translation: AAH12948.1 |
CCDSi | CCDS7048.1 |
RefSeqi | NP_612471.1, NM_138462.2 |
UniGenei | Hs.128096 |
3D structure databases
ProteinModelPortali | Q96E35 |
ModBasei | Search... |
MobiDBi | Search... |
Protein-protein interaction databases
BioGridi | 125490, 60 interactors |
IntActi | Q96E35, 52 interactors |
MINTi | Q96E35 |
STRINGi | 9606.ENSP00000298585 |
PTM databases
iPTMneti | Q96E35 |
PhosphoSitePlusi | Q96E35 |
Polymorphism and mutation databases
BioMutai | ZMYND19 |
DMDMi | 46397255 |
Proteomic databases
EPDi | Q96E35 |
jPOSTi | Q96E35 |
MaxQBi | Q96E35 |
PaxDbi | Q96E35 |
PeptideAtlasi | Q96E35 |
PRIDEi | Q96E35 |
ProteomicsDBi | 76369 |
Protocols and materials databases
DNASUi | 116225 |
Structural Biology Knowledgebase | Search... |
Genome annotation databases
Ensembli | ENST00000298585; ENSP00000298585; ENSG00000165724 |
GeneIDi | 116225 |
KEGGi | hsa:116225 |
UCSCi | uc004cno.2 human |
Organism-specific databases
CTDi | 116225 |
EuPathDBi | HostDB:ENSG00000165724.5 |
GeneCardsi | ZMYND19 |
HGNCi | HGNC:21146 ZMYND19 |
HPAi | HPA020642 HPA050761 |
MIMi | 611424 gene |
neXtProti | NX_Q96E35 |
OpenTargetsi | ENSG00000165724 |
PharmGKBi | PA134878875 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG410IF0H Eukaryota ENOG410YJQA LUCA |
GeneTreei | ENSGT00390000012479 |
HOGENOMi | HOG000231532 |
HOVERGENi | HBG058268 |
InParanoidi | Q96E35 |
OMAi | CREKKRT |
OrthoDBi | 1254383at2759 |
PhylomeDBi | Q96E35 |
TreeFami | TF329209 |
Miscellaneous databases
ChiTaRSi | ZMYND19 human |
GenomeRNAii | 116225 |
PROi | PR:Q96E35 |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000165724 Expressed in 184 organ(s), highest expression level in right testis |
Genevisiblei | Q96E35 HS |
Family and domain databases
InterProi | View protein in InterPro IPR003615 HNH_nuc IPR032978 ZMYND19 IPR002893 Znf_MYND |
PANTHERi | PTHR13244:SF5 PTHR13244:SF5, 1 hit |
Pfami | View protein in Pfam PF13392 HNH_3, 1 hit PF01753 zf-MYND, 1 hit |
PROSITEi | View protein in PROSITE PS01360 ZF_MYND_1, 1 hit PS50865 ZF_MYND_2, 1 hit |
ProtoNeti | Search... |
Entry informationi
Entry namei | ZMY19_HUMAN | |
Accessioni | Q96E35Primary (citable) accession number: Q96E35 Secondary accession number(s): Q5T366 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 13, 2004 |
Last sequence update: | December 1, 2001 | |
Last modified: | February 13, 2019 | |
This is version 133 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Complete proteome, Reference proteomeDocuments
- MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - Human chromosome 9
Human chromosome 9: entries, gene names and cross-references to MIM