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Protein

Zinc finger MYND domain-containing protein 19

Gene

ZMYND19

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May be involved as a regulatory molecule in GPR24/MCH-R1 signaling.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri164 – 212MYND-typePROSITE-ProRule annotationAdd BLAST49

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger MYND domain-containing protein 19
Alternative name(s):
Melanin-concentrating hormone receptor 1-interacting zinc finger protein
Short name:
MCH-R1-interacting zinc finger protein
Gene namesi
Name:ZMYND19
Synonyms:MIZIP
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 9

Organism-specific databases

EuPathDBiHostDB:ENSG00000165724.5
HGNCiHGNC:21146 ZMYND19
MIMi611424 gene
neXtProtiNX_Q96E35

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell membrane, Cytoplasm, Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000165724
PharmGKBiPA134878875

Polymorphism and mutation databases

BioMutaiZMYND19
DMDMi46397255

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002183191 – 227Zinc finger MYND domain-containing protein 19Add BLAST227

Proteomic databases

EPDiQ96E35
MaxQBiQ96E35
PaxDbiQ96E35
PeptideAtlasiQ96E35
PRIDEiQ96E35
ProteomicsDBi76369

PTM databases

GlyConnecti1906
iPTMnetiQ96E35
PhosphoSitePlusiQ96E35

Expressioni

Tissue specificityi

Expressed in brain, testis, placenta, heart, liver, skeletal muscle, kidney and stomach.1 Publication

Gene expression databases

BgeeiENSG00000165724 Expressed in 184 organ(s), highest expression level in right testis
CleanExiHS_ZMYND19
GenevisibleiQ96E35 HS

Organism-specific databases

HPAiHPA020642
HPA050761

Interactioni

Subunit structurei

Interacts with GPR24/MCH-R1.1 Publication

Binary interactionsi

Protein-protein interaction databases

BioGridi125490, 60 interactors
IntActiQ96E35, 52 interactors
MINTiQ96E35
STRINGi9606.ENSP00000298585

Structurei

3D structure databases

ProteinModelPortaliQ96E35
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi158 – 161Poly-Glu4

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri164 – 212MYND-typePROSITE-ProRule annotationAdd BLAST49

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiENOG410IF0H Eukaryota
ENOG410YJQA LUCA
GeneTreeiENSGT00390000012479
HOGENOMiHOG000231532
HOVERGENiHBG058268
InParanoidiQ96E35
OMAiCREKKRT
OrthoDBiEOG091G0O2G
PhylomeDBiQ96E35
TreeFamiTF329209

Family and domain databases

InterProiView protein in InterPro
IPR003615 HNH_nuc
IPR032978 ZMYND19
IPR002893 Znf_MYND
PANTHERiPTHR13244:SF5 PTHR13244:SF5, 1 hit
PfamiView protein in Pfam
PF13392 HNH_3, 1 hit
PF01753 zf-MYND, 1 hit
PROSITEiView protein in PROSITE
PS01360 ZF_MYND_1, 1 hit
PS50865 ZF_MYND_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q96E35-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTDFKLGIVR LGRVAGKTKY TLIDEQDIPL VESYSFEARM EVDADGNGAK
60 70 80 90 100
IFAYAFDKNR GRGSGRLLHE LLWERHRGGV APGFQVVHLN AVTVDNRLDN
110 120 130 140 150
LQLVPWGWRP KAEETSSKQR EQSLYWLAIQ QLPTDPIEEQ FPVLNVTRYY
160 170 180 190 200
NANGDVVEEE ENSCTYYECH YPPCTVIEKQ LREFNICGRC QVARYCGSQC
210 220
QQKDWPAHKK HCRERKRPFQ HELEPER
Length:227
Mass (Da):26,433
Last modified:December 1, 2001 - v1
Checksum:i906F0B51B670063A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ298882 mRNA Translation: CAC16691.1
AL365502 Genomic DNA No translation available.
BC012948 mRNA Translation: AAH12948.1
CCDSiCCDS7048.1
RefSeqiNP_612471.1, NM_138462.2
UniGeneiHs.128096

Genome annotation databases

EnsembliENST00000298585; ENSP00000298585; ENSG00000165724
GeneIDi116225
KEGGihsa:116225
UCSCiuc004cno.2 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ298882 mRNA Translation: CAC16691.1
AL365502 Genomic DNA No translation available.
BC012948 mRNA Translation: AAH12948.1
CCDSiCCDS7048.1
RefSeqiNP_612471.1, NM_138462.2
UniGeneiHs.128096

3D structure databases

ProteinModelPortaliQ96E35
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi125490, 60 interactors
IntActiQ96E35, 52 interactors
MINTiQ96E35
STRINGi9606.ENSP00000298585

PTM databases

GlyConnecti1906
iPTMnetiQ96E35
PhosphoSitePlusiQ96E35

Polymorphism and mutation databases

BioMutaiZMYND19
DMDMi46397255

Proteomic databases

EPDiQ96E35
MaxQBiQ96E35
PaxDbiQ96E35
PeptideAtlasiQ96E35
PRIDEiQ96E35
ProteomicsDBi76369

Protocols and materials databases

DNASUi116225
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000298585; ENSP00000298585; ENSG00000165724
GeneIDi116225
KEGGihsa:116225
UCSCiuc004cno.2 human

Organism-specific databases

CTDi116225
EuPathDBiHostDB:ENSG00000165724.5
GeneCardsiZMYND19
HGNCiHGNC:21146 ZMYND19
HPAiHPA020642
HPA050761
MIMi611424 gene
neXtProtiNX_Q96E35
OpenTargetsiENSG00000165724
PharmGKBiPA134878875
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IF0H Eukaryota
ENOG410YJQA LUCA
GeneTreeiENSGT00390000012479
HOGENOMiHOG000231532
HOVERGENiHBG058268
InParanoidiQ96E35
OMAiCREKKRT
OrthoDBiEOG091G0O2G
PhylomeDBiQ96E35
TreeFamiTF329209

Miscellaneous databases

ChiTaRSiZMYND19 human
GenomeRNAii116225
PROiPR:Q96E35
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000165724 Expressed in 184 organ(s), highest expression level in right testis
CleanExiHS_ZMYND19
GenevisibleiQ96E35 HS

Family and domain databases

InterProiView protein in InterPro
IPR003615 HNH_nuc
IPR032978 ZMYND19
IPR002893 Znf_MYND
PANTHERiPTHR13244:SF5 PTHR13244:SF5, 1 hit
PfamiView protein in Pfam
PF13392 HNH_3, 1 hit
PF01753 zf-MYND, 1 hit
PROSITEiView protein in PROSITE
PS01360 ZF_MYND_1, 1 hit
PS50865 ZF_MYND_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiZMY19_HUMAN
AccessioniPrimary (citable) accession number: Q96E35
Secondary accession number(s): Q5T366
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: December 1, 2001
Last modified: October 10, 2018
This is version 131 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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Main funding by: National Institutes of Health

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