ZMYND19

Functionⁱ

May be involved as a regulatory molecule in GPR24/MCH-R1 signaling.

Regions

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Zinc fingerⁱ	164 – 212	MYND-typePROSITE-ProRule annotationAdd BLAST		49

GO - Molecular functionⁱ

metal ion binding Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Ligand	Metal-binding, Zinc

Ligand

Metal-binding, Zinc

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Zinc finger MYND domain-containing protein 19 Alternative name(s): Melanin-concentrating hormone receptor 1-interacting zinc finger protein Short name: MCH-R1-interacting zinc finger protein
Gene namesⁱ	Name:ZMYND19 Synonyms:MIZIP
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 9

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000165724.5
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:21146 ZMYND19
MIMⁱ	611424 gene
neXtProtⁱ	NX_Q96E35

Keywords - Cellular componentⁱ

Cell membrane, Cytoplasm, Membrane

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000165724
PharmGKBⁱ	PA134878875

Polymorphism and mutation databases

BioMutaⁱ	ZMYND19
DMDMⁱ	46397255

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000218319	1 – 227	Zinc finger MYND domain-containing protein 19Add BLAST		227

Proteomic databases

EPDⁱ	Q96E35
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q96E35
PaxDbⁱ	Q96E35
PeptideAtlas More...PeptideAtlasⁱ	Q96E35
PRIDEⁱ	Q96E35
ProteomicsDBⁱ	76369

PTM databases

GlyConnectⁱ	1906
iPTMnetⁱ	Q96E35
PhosphoSitePlusⁱ	Q96E35

Expressionⁱ

Tissue specificityⁱ

Expressed in brain, testis, placenta, heart, liver, skeletal muscle, kidney and stomach.1 Publication

Gene expression databases

Bgeeⁱ	ENSG00000165724 Expressed in 184 organ(s), highest expression level in right testis
CleanExⁱ	HS_ZMYND19
Genevisibleⁱ	Q96E35 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA020642 HPA050761

HPAⁱ

HPA020642
HPA050761

Interactionⁱ

Subunit structureⁱ

Interacts with GPR24/MCH-R1.1 Publication

Binary interactionsⁱ

With	Entry	#Exp.	IntAct
CCNI	Q14094	4	EBI-746595,EBI-1104653
CEACAM6	P40199	4	EBI-746595,EBI-4314501
ENOX1	Q8TC92	5	EBI-746595,EBI-713221
FIP1L1	Q6UN15	3	EBI-746595,EBI-1021914
HACL1	Q9UJ83	6	EBI-746595,EBI-746580
INCA1	Q0VD86	3	EBI-746595,EBI-6509505
KCTD13	Q8WZ19	6	EBI-746595,EBI-742916
LZTS2	Q9BRK4	4	EBI-746595,EBI-741037
NAB2	Q15742	6	EBI-746595,EBI-8641936
PNMA5	Q96PV4	5	EBI-746595,EBI-10171633
SAXO1	Q8IYX7	5	EBI-746595,EBI-3957636
SELENOV	P59797	5	EBI-746595,EBI-10216195
TOX4	O94842	5	EBI-746595,EBI-948613
TRIM27	P14373	3	EBI-746595,EBI-719493

Protein-protein interaction databases

BioGridⁱ	125490, 60 interactors
IntActⁱ	Q96E35, 52 interactors
Molecular INTeraction database More...MINTⁱ	Q96E35
STRINGⁱ	9606.ENSP00000298585

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q96E35
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Compositional bias

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Compositional biasⁱ	158 – 161	Poly-Glu		4

Zinc finger

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Zinc fingerⁱ	164 – 212	MYND-typePROSITE-ProRule annotationAdd BLAST		49

Keywords - Domainⁱ

Zinc-finger

Phylogenomic databases

eggNOGⁱ	ENOG410IF0H Eukaryota ENOG410YJQA LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000012479
HOGENOMⁱ	HOG000231532
HOVERGENⁱ	HBG058268
InParanoidⁱ	Q96E35
OMAⁱ	CREKKRT
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0O2G
PhylomeDBⁱ	Q96E35
TreeFamⁱ	TF329209

Family and domain databases

InterProⁱ	View protein in InterPro IPR003615 HNH_nuc IPR032978 ZMYND19 IPR002893 Znf_MYND
PANTHERⁱ	PTHR13244:SF5 PTHR13244:SF5, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF13392 HNH_3, 1 hit PF01753 zf-MYND, 1 hit
PROSITEⁱ	View protein in PROSITE PS01360 ZF_MYND_1, 1 hit PS50865 ZF_MYND_2, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Q96E35-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MTDFKLGIVR LGRVAGKTKY TLIDEQDIPL VESYSFEARM EVDADGNGAK 
        60         70         80         90        100
IFAYAFDKNR GRGSGRLLHE LLWERHRGGV APGFQVVHLN AVTVDNRLDN 
       110        120        130        140        150
LQLVPWGWRP KAEETSSKQR EQSLYWLAIQ QLPTDPIEEQ FPVLNVTRYY 
       160        170        180        190        200
NANGDVVEEE ENSCTYYECH YPPCTVIEKQ LREFNICGRC QVARYCGSQC 
       210        220 
QQKDWPAHKK HCRERKRPFQ HELEPER

Length:227

Mass (Da):26,433

Last modified:December 1, 2001 - v1

Checksum:ⁱ906F0B51B670063A

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AJ298882 mRNA Translation: CAC16691.1 AL365502 Genomic DNA No translation available. BC012948 mRNA Translation: AAH12948.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS7048.1
NCBI Reference Sequences More...RefSeqⁱ	NP_612471.1, NM_138462.2
UniGeneⁱ	Hs.128096

Genome annotation databases

Ensemblⁱ	ENST00000298585; ENSP00000298585; ENSG00000165724
GeneIDⁱ	116225
KEGGⁱ	hsa:116225
UCSC genome browser More...UCSCⁱ	uc004cno.2 human

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q96E35	Zinc finger MYND domain-containing protein 19		MOUSE		227	UniRef100_Q96E35
Zinc finger MYND domain-containing protein 19		RAT		227
ZMYND19 isoform 1		PANTR		227
Zinc finger MYND domain-containing protein 19		MACMU		227
Zinc finger MYND domain-containing protein 19		CALJA		227
+9

Protein	Similar proteins		Species	Score	Length	Source
Q96E35	Zinc finger MYND domain-containing protein 19		MOUSE		227	UniRef90_Q96E35
Zinc finger MYND domain-containing protein 19		RAT		227
ZMYND19 isoform 1		PANTR		227
Zinc finger MYND domain-containing protein 19		MACMU		227
Zinc finger MYND domain-containing protein 19		CALJA		227
+51

Protein	Similar proteins		Species	Score	Length	Source
Q96E35	Zinc finger MYND domain-containing protein 19		MOUSE		227	UniRef50_Q96E35
Zinc finger MYND domain-containing protein 19		RAT		227
ZMYND19 isoform 1		PANTR		227
Zinc finger MYND domain-containing protein 19		MACMU		227
Zinc finger MYND domain-containing protein 19		CALJA		227
+254

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AJ298882 mRNA Translation: CAC16691.1 AL365502 Genomic DNA No translation available. BC012948 mRNA Translation: AAH12948.1
CCDSⁱ	CCDS7048.1
RefSeqⁱ	NP_612471.1, NM_138462.2
UniGeneⁱ	Hs.128096

3D structure databases

ProteinModelPortalⁱ	Q96E35
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	125490, 60 interactors
IntActⁱ	Q96E35, 52 interactors
MINTⁱ	Q96E35
STRINGⁱ	9606.ENSP00000298585

PTM databases

GlyConnectⁱ	1906
iPTMnetⁱ	Q96E35
PhosphoSitePlusⁱ	Q96E35

Polymorphism and mutation databases

BioMutaⁱ	ZMYND19
DMDMⁱ	46397255

Proteomic databases

EPDⁱ	Q96E35
MaxQBⁱ	Q96E35
PaxDbⁱ	Q96E35
PeptideAtlasⁱ	Q96E35
PRIDEⁱ	Q96E35
ProteomicsDBⁱ	76369

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	116225
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000298585; ENSP00000298585; ENSG00000165724
GeneIDⁱ	116225
KEGGⁱ	hsa:116225
UCSCⁱ	uc004cno.2 human

Organism-specific databases

CTDⁱ	116225
EuPathDBⁱ	HostDB:ENSG00000165724.5
GeneCardsⁱ	ZMYND19
HGNCⁱ	HGNC:21146 ZMYND19
HPAⁱ	HPA020642 HPA050761
MIMⁱ	611424 gene
neXtProtⁱ	NX_Q96E35
OpenTargetsⁱ	ENSG00000165724
PharmGKBⁱ	PA134878875
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	ENOG410IF0H Eukaryota ENOG410YJQA LUCA
GeneTreeⁱ	ENSGT00390000012479
HOGENOMⁱ	HOG000231532
HOVERGENⁱ	HBG058268
InParanoidⁱ	Q96E35
OMAⁱ	CREKKRT
OrthoDBⁱ	EOG091G0O2G
PhylomeDBⁱ	Q96E35
TreeFamⁱ	TF329209

Miscellaneous databases

ChiTaRSⁱ	ZMYND19 human
GenomeRNAiⁱ	116225
Protein Ontology More...PROⁱ	PR:Q96E35
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000165724 Expressed in 184 organ(s), highest expression level in right testis
CleanExⁱ	HS_ZMYND19
Genevisibleⁱ	Q96E35 HS

Family and domain databases

InterProⁱ	View protein in InterPro IPR003615 HNH_nuc IPR032978 ZMYND19 IPR002893 Znf_MYND
PANTHERⁱ	PTHR13244:SF5 PTHR13244:SF5, 1 hit
Pfamⁱ	View protein in Pfam PF13392 HNH_3, 1 hit PF01753 zf-MYND, 1 hit
PROSITEⁱ	View protein in PROSITE PS01360 ZF_MYND_1, 1 hit PS50865 ZF_MYND_2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	ZMY19_HUMAN
Accessionⁱ	Q96E35Primary (citable) accession number: Q96E35 Secondary accession number(s): Q5T366
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	April 13, 2004
	Last sequence update:	December 1, 2001
	Last modified:	October 10, 2018
	This is version 131 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
Human chromosome 9
Human chromosome 9: entries, gene names and cross-references to MIM

UniProtKB

UniParc

Help

UniRef

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Annotation systems

Supporting data

UniProtKB - Q96E35 (ZMY19_HUMAN)

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Zinc finger MYND domain-containing protein 19

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Plasma membrane

Other locations

Plasma Membrane

Other locations

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Zinc finger

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ