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Protein

Transcription termination factor 3, mitochondrial

Gene

MTERF3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Binds promoter DNA and regulates initiation of transcription (PubMed:17662942). Required for normal mitochondrial transcription and translation, and for normal assembly of mitochondrial respiratory complexes. Required for normal mitochondrial function (By similarity). Maintains 16S rRNA levels and functions in mitochondrial ribosome assembly by regulating the biogenesis of the 39S ribosomal subunit (By similarity).By similarity1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • double-stranded DNA binding Source: InterPro
  • transcription regulatory region DNA binding Source: UniProtKB

GO - Biological processi

  • macroautophagy Source: Reactome
  • mitochondrial ribosome assembly Source: GO_Central
  • mitochondrial transcription Source: GO_Central
  • mitochondrial translation Source: GO_Central
  • negative regulation of transcription, DNA-templated Source: UniProtKB

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processRibosome biogenesis, Transcription, Transcription regulation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-5205685 Pink/Parkin Mediated Mitophagy

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transcription termination factor 3, mitochondrial
Alternative name(s):
Mitochondrial transcription termination factor 3
Short name:
mTERF3
mTERF domain-containing protein 1, mitochondrial
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MTERF3
Synonyms:MTERFD1
ORF Names:CGI-12
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000156469.8

Human Gene Nomenclature Database

More...
HGNCi
HGNC:24258 MTERF3

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
616930 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q96E29

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000156469

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142671309

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
MTERFD1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74731522

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 68Mitochondrion1 PublicationAdd BLAST68
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000025545769 – 417Transcription termination factor 3, mitochondrialAdd BLAST349

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q96E29

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q96E29

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q96E29

PeptideAtlas

More...
PeptideAtlasi
Q96E29

PRoteomics IDEntifications database

More...
PRIDEi
Q96E29

ProteomicsDB human proteome resource

More...
ProteomicsDBi
76367
76368 [Q96E29-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q96E29

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q96E29

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highly expressed in heart, liver, kidney and testis. Detected at lower levels in brain, spleen and lung.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000156469 Expressed in 224 organ(s), highest expression level in oocyte

CleanEx database of gene expression profiles

More...
CleanExi
HS_MTERFD1

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q96E29 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q96E29 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA002966

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
119209, 44 interactors

Protein interaction database and analysis system

More...
IntActi
Q96E29, 31 interactors

Molecular INTeraction database

More...
MINTi
Q96E29

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000287025

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1417
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

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ProteinModelPortali
Q96E29

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q96E29

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
Q96E29

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Contains seven structural repeats of about 35 residues, where each repeat contains three helices. The repeats form a superhelical structure with a solenoid shape.1 Publication

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the mTERF family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1267 Eukaryota
ENOG410XT49 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000005801

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000044443

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG062577

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q96E29

KEGG Orthology (KO)

More...
KOi
K15032

Identification of Orthologs from Complete Genome Data

More...
OMAi
NNFYFVR

Database of Orthologous Groups

More...
OrthoDBi
EOG091G0AZ7

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q96E29

TreeFam database of animal gene trees

More...
TreeFami
TF317943

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.70.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003690 MTERF
IPR038538 MTERF_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02536 mTERF, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00733 Mterf, 6 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q96E29-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MALSAQQIPR WFNSVKLRSL INAAQLTKRF TRPARTLLHG FSAQPQISSD
60 70 80 90 100
NCFLQWGFKT YRTSSLWNSS QSTSSSSQEN NSAQSSLLPS MNEQSQKTQN
110 120 130 140 150
ISSFDSELFL EELDELPPLS PMQPISEEEA IQIIADPPLP PASFTLRDYV
160 170 180 190 200
DHSETLQKLV LLGVDLSKIE KHPEAANLLL RLDFEKDIKQ MLLFLKDVGI
210 220 230 240 250
EDNQLGAFLT KNHAIFSEDL ENLKTRVAYL HSKNFSKADV AQMVRKAPFL
260 270 280 290 300
LNFSVERLDN RLGFFQKELE LSVKKTRDLV VRLPRLLTGS LEPVKENMKV
310 320 330 340 350
YRLELGFKHN EIQHMITRIP KMLTANKMKL TETFDFVHNV MSIPHHIIVK
360 370 380 390 400
FPQVFNTRLF KVKERHLFLT YLGRAQYDPA KPNYISLDKL VSIPDEIFCE
410
EIAKASVQDF EKFLKTL
Length:417
Mass (Da):47,971
Last modified:March 1, 2004 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2062EFE902584696
GO
Isoform 2 (identifier: Q96E29-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-90: Missing.

Show »
Length:327
Mass (Da):37,907
Checksum:i3C396BD9DC336AE6
GO
Isoform 3 (identifier: Q96E29-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-121: Missing.

Note: No experimental confirmation available.
Show »
Length:296
Mass (Da):34,358
Checksum:i539D802B0FB47ABE
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E5RIK9E5RIK9_HUMAN
Transcription termination factor 3,...
MTERF3
361Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RIY4E5RIY4_HUMAN
Transcription termination factor 3,...
MTERF3
173Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E5RI75E5RI75_HUMAN
Transcription termination factor 3,...
MTERF3
67Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAD27721 differs from that shown. Reason: Frameshift at positions 261 and 262.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti153S → P in BAG50978 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_053786396E → G. Corresponds to variant dbSNP:rs7461970Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0539851 – 121Missing in isoform 3. 1 PublicationAdd BLAST121
Alternative sequenceiVSP_0212921 – 90Missing in isoform 2. 1 PublicationAdd BLAST90

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF132946 mRNA Translation: AAD27721.1 Frameshift.
AK001801 mRNA Translation: BAG50978.1
AP003465 Genomic DNA No translation available.
CH471060 Genomic DNA Translation: EAW91752.1
BC012995 mRNA Translation: AAH12995.2

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS6270.1 [Q96E29-1]

NCBI Reference Sequences

More...
RefSeqi
NP_057026.3, NM_015942.4 [Q96E29-1]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.308613

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000287025; ENSP00000287025; ENSG00000156469 [Q96E29-1]
ENST00000522822; ENSP00000430138; ENSG00000156469 [Q96E29-3]

Database of genes from NCBI RefSeq genomes

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GeneIDi
51001

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:51001

UCSC genome browser

More...
UCSCi
uc003yhr.3 human [Q96E29-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF132946 mRNA Translation: AAD27721.1 Frameshift.
AK001801 mRNA Translation: BAG50978.1
AP003465 Genomic DNA No translation available.
CH471060 Genomic DNA Translation: EAW91752.1
BC012995 mRNA Translation: AAH12995.2
CCDSiCCDS6270.1 [Q96E29-1]
RefSeqiNP_057026.3, NM_015942.4 [Q96E29-1]
UniGeneiHs.308613

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3M66X-ray1.60A148-417[»]
ProteinModelPortaliQ96E29
SMRiQ96E29
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi119209, 44 interactors
IntActiQ96E29, 31 interactors
MINTiQ96E29
STRINGi9606.ENSP00000287025

PTM databases

iPTMnetiQ96E29
PhosphoSitePlusiQ96E29

Polymorphism and mutation databases

BioMutaiMTERFD1
DMDMi74731522

Proteomic databases

EPDiQ96E29
MaxQBiQ96E29
PaxDbiQ96E29
PeptideAtlasiQ96E29
PRIDEiQ96E29
ProteomicsDBi76367
76368 [Q96E29-2]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
51001
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000287025; ENSP00000287025; ENSG00000156469 [Q96E29-1]
ENST00000522822; ENSP00000430138; ENSG00000156469 [Q96E29-3]
GeneIDi51001
KEGGihsa:51001
UCSCiuc003yhr.3 human [Q96E29-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
51001
EuPathDBiHostDB:ENSG00000156469.8

GeneCards: human genes, protein and diseases

More...
GeneCardsi
MTERF3
HGNCiHGNC:24258 MTERF3
HPAiHPA002966
MIMi616930 gene
neXtProtiNX_Q96E29
OpenTargetsiENSG00000156469
PharmGKBiPA142671309

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1267 Eukaryota
ENOG410XT49 LUCA
GeneTreeiENSGT00390000005801
HOGENOMiHOG000044443
HOVERGENiHBG062577
InParanoidiQ96E29
KOiK15032
OMAiNNFYFVR
OrthoDBiEOG091G0AZ7
PhylomeDBiQ96E29
TreeFamiTF317943

Enzyme and pathway databases

ReactomeiR-HSA-5205685 Pink/Parkin Mediated Mitophagy

Miscellaneous databases

EvolutionaryTraceiQ96E29

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
51001

Protein Ontology

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PROi
PR:Q96E29

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000156469 Expressed in 224 organ(s), highest expression level in oocyte
CleanExiHS_MTERFD1
ExpressionAtlasiQ96E29 baseline and differential
GenevisibleiQ96E29 HS

Family and domain databases

Gene3Di1.25.70.10, 1 hit
InterProiView protein in InterPro
IPR003690 MTERF
IPR038538 MTERF_sf
PfamiView protein in Pfam
PF02536 mTERF, 1 hit
SMARTiView protein in SMART
SM00733 Mterf, 6 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMTEF3_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96E29
Secondary accession number(s): B3KMG6, G3V130, Q9Y301
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: March 1, 2004
Last modified: November 7, 2018
This is version 133 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 8
    Human chromosome 8: entries, gene names and cross-references to MIM
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  6. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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