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Entry version 141 (05 Jun 2019)
Sequence version 1 (01 Dec 2001)
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Protein

Ribosome-recycling factor, mitochondrial

Gene

MRRF

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processProtein biosynthesis

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-5419276 Mitochondrial translation termination

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ribosome-recycling factor, mitochondrial
Short name:
RRF
Alternative name(s):
Ribosome-releasing factor, mitochondrial
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MRRF
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 9

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:7234 MRRF

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
604602 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q96E11

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
92399

Open Targets

More...
OpenTargetsi
ENSG00000148187

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA31029

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
MRRF

Domain mapping of disease mutations (DMDM)

More...
DMDMi
62901043

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a transit peptide.<p><a href='/help/transit' target='_top'>More...</a></p>Transit peptidei1 – 55MitochondrionSequence analysisAdd BLAST55
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000003108056 – 262Ribosome-recycling factor, mitochondrialAdd BLAST207

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q96E11

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q96E11

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q96E11

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q96E11

PeptideAtlas

More...
PeptideAtlasi
Q96E11

PRoteomics IDEntifications database

More...
PRIDEi
Q96E11

ProteomicsDB human proteome resource

More...
ProteomicsDBi
76354
76355 [Q96E11-2]
76356 [Q96E11-3]
76357 [Q96E11-4]
76358 [Q96E11-5]
76359 [Q96E11-6]
76360 [Q96E11-7]
76361 [Q96E11-8]

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
Q96E11-3 [Q96E11-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q96E11

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q96E11

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000148187 Expressed in 168 organ(s), highest expression level in right testis

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q96E11 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q96E11 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA047177
HPA049987

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
124944, 43 interactors

Protein interaction database and analysis system

More...
IntActi
Q96E11, 29 interactors

Molecular INTeraction database

More...
MINTi
Q96E11

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000343867

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q96E11

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the RRF family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4759 Eukaryota
COG0233 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000005084

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q96E11

KEGG Orthology (KO)

More...
KOi
K02838

Identification of Orthologs from Complete Genome Data

More...
OMAi
YYGAETP

Database of Orthologous Groups

More...
OrthoDBi
1590112at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q96E11

TreeFam database of animal gene trees

More...
TreeFami
TF323691

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002661 Ribosome_recyc_fac
IPR023584 Ribosome_recyc_fac_dom
IPR036191 RRF_sf

The PANTHER Classification System

More...
PANTHERi
PTHR20982 PTHR20982, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01765 RRF, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF55194 SSF55194, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (8+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 8 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 8 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q96E11-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MALGLKCFRM VHPTFRNYLA ASIRPVSEVT LKTVHERQHG HRQYMAYSAV
60 70 80 90 100
PVRHFATKKA KAKGKGQSQT RVNINAALVE DIINLEEVNE EMKSVIEALK
110 120 130 140 150
DNFNKTLNIR TSPGSLDKIA VVTADGKLAL NQISQISMKS PQLILVNMAS
160 170 180 190 200
FPECTAAAIK AIRESGMNLN PEVEGTLIRV PIPQVTREHR EMLVKLAKQN
210 220 230 240 250
TNKAKDSLRK VRTNSMNKLK KSKDTVSEDT IRLIEKQISQ MADDTVAELD
260
RHLAVKTKEL LG
Length:262
Mass (Da):29,277
Last modified:December 1, 2001 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA4343465B5C9F5DE
GO
Isoform 2 (identifier: Q96E11-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     185-201: VTREHREMLVKLAKQNT → SAKWPMTQWQNWTGIWQ
     202-262: Missing.

Note: No experimental confirmation available.
Show »
Length:201
Mass (Da):22,450
Checksum:i9965A98B2AD33AC5
GO
Isoform 3 (identifier: Q96E11-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-44: Missing.

Note: Derived from EST data. No experimental confirmation available.
Show »
Length:218
Mass (Da):24,115
Checksum:iD2393AB713FD04FB
GO
Isoform 4 (identifier: Q96E11-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     154-262: CTAAAIKAIR...LAVKTKELLG → ELAWIRSLRVPGIRSHLYHQLAV

Note: Derived from EST data. No experimental confirmation available.
Show »
Length:176
Mass (Da):19,742
Checksum:iFEDFE00D670084CF
GO
Isoform 5 (identifier: Q96E11-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     154-158: CTAAA → VRWPC
     159-262: Missing.

Note: Derived from EST data. No experimental confirmation available.
Show »
Length:158
Mass (Da):17,687
Checksum:i395151EF011182AB
GO
Isoform 6 (identifier: Q96E11-6) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     154-168: CTAAAIKAIRESGMN → TMKQIKQYFNGPNVA
     169-262: Missing.

Note: Derived from EST data. No experimental confirmation available.
Show »
Length:168
Mass (Da):18,766
Checksum:i51468DB2F03B79FB
GO
Isoform 7 (identifier: Q96E11-7) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-44: Missing.
     154-168: CTAAAIKAIRESGMN → TMKQIKQYFNGPNVA
     169-262: Missing.

Note: Derived from EST data. No experimental confirmation available.
Show »
Length:124
Mass (Da):13,604
Checksum:iC8C91CFD6BF33A9F
GO
Isoform 8 (identifier: Q96E11-8) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     62-113: Missing.

Note: Derived from EST data. No experimental confirmation available.
Show »
Length:210
Mass (Da):23,511
Checksum:iF8CEBCB81AAE3D4E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
X6RDS5X6RDS5_HUMAN
Ribosome-recycling factor, mitochon...
MRRF
153Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_051885216M → V. Corresponds to variant dbSNP:rs2297483EnsemblClinVar.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0134831 – 44Missing in isoform 3 and isoform 7. CuratedAdd BLAST44
Alternative sequenceiVSP_04201962 – 113Missing in isoform 8. 1 PublicationAdd BLAST52
Alternative sequenceiVSP_013484154 – 262CTAAA…KELLG → ELAWIRSLRVPGIRSHLYHQ LAV in isoform 4. CuratedAdd BLAST109
Alternative sequenceiVSP_013485154 – 168CTAAA…ESGMN → TMKQIKQYFNGPNVA in isoform 6 and isoform 7. 1 PublicationAdd BLAST15
Alternative sequenceiVSP_013486154 – 158CTAAA → VRWPC in isoform 5. 1 Publication5
Alternative sequenceiVSP_013487159 – 262Missing in isoform 5. 1 PublicationAdd BLAST104
Alternative sequenceiVSP_013488169 – 262Missing in isoform 6 and isoform 7. 1 PublicationAdd BLAST94
Alternative sequenceiVSP_013489185 – 201VTREH…AKQNT → SAKWPMTQWQNWTGIWQ in isoform 2. 1 PublicationAdd BLAST17
Alternative sequenceiVSP_013490202 – 262Missing in isoform 2. 1 PublicationAdd BLAST61

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK291603 mRNA Translation: BAF84292.1
AK298046 mRNA Translation: BAH12711.1
AK291809 mRNA Translation: BAF84498.1
AK292790 mRNA Translation: BAF85479.1
AK300718 mRNA Translation: BAH13333.1
AK316266 mRNA Translation: BAH14637.1
AL162424 Genomic DNA No translation available.
CH471090 Genomic DNA Translation: EAW87525.1
BC013049 mRNA Translation: AAH13049.1
BC053604 mRNA Translation: AAH53604.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS48013.1 [Q96E11-2]
CCDS55336.1 [Q96E11-8]
CCDS6840.1 [Q96E11-1]
CCDS87684.1 [Q96E11-3]

NCBI Reference Sequences

More...
RefSeqi
NP_001166983.1, NM_001173512.2 [Q96E11-8]
NP_001333270.1, NM_001346341.1 [Q96E11-1]
NP_001333272.1, NM_001346343.1 [Q96E11-3]
NP_620132.1, NM_138777.4 [Q96E11-1]
NP_954646.1, NM_199177.3 [Q96E11-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000297908; ENSP00000297908; ENSG00000148187 [Q96E11-8]
ENST00000344641; ENSP00000343867; ENSG00000148187 [Q96E11-1]
ENST00000373723; ENSP00000362828; ENSG00000148187 [Q96E11-2]
ENST00000373729; ENSP00000362834; ENSG00000148187 [Q96E11-3]
ENST00000394315; ENSP00000377850; ENSG00000148187 [Q96E11-2]
ENST00000467864; ENSP00000433288; ENSG00000148187 [Q96E11-4]
ENST00000470366; ENSP00000434807; ENSG00000148187 [Q96E11-6]
ENST00000489572; ENSP00000436360; ENSG00000148187 [Q96E11-6]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
92399

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:92399

UCSC genome browser

More...
UCSCi
uc010mwa.4 human [Q96E11-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK291603 mRNA Translation: BAF84292.1
AK298046 mRNA Translation: BAH12711.1
AK291809 mRNA Translation: BAF84498.1
AK292790 mRNA Translation: BAF85479.1
AK300718 mRNA Translation: BAH13333.1
AK316266 mRNA Translation: BAH14637.1
AL162424 Genomic DNA No translation available.
CH471090 Genomic DNA Translation: EAW87525.1
BC013049 mRNA Translation: AAH13049.1
BC053604 mRNA Translation: AAH53604.1
CCDSiCCDS48013.1 [Q96E11-2]
CCDS55336.1 [Q96E11-8]
CCDS6840.1 [Q96E11-1]
CCDS87684.1 [Q96E11-3]
RefSeqiNP_001166983.1, NM_001173512.2 [Q96E11-8]
NP_001333270.1, NM_001346341.1 [Q96E11-1]
NP_001333272.1, NM_001346343.1 [Q96E11-3]
NP_620132.1, NM_138777.4 [Q96E11-1]
NP_954646.1, NM_199177.3 [Q96E11-2]

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
6NU2electron microscopy3.90z59-262[»]
SMRiQ96E11
ModBaseiSearch...

Protein-protein interaction databases

BioGridi124944, 43 interactors
IntActiQ96E11, 29 interactors
MINTiQ96E11
STRINGi9606.ENSP00000343867

PTM databases

iPTMnetiQ96E11
PhosphoSitePlusiQ96E11

Polymorphism and mutation databases

BioMutaiMRRF
DMDMi62901043

Proteomic databases

EPDiQ96E11
jPOSTiQ96E11
MaxQBiQ96E11
PaxDbiQ96E11
PeptideAtlasiQ96E11
PRIDEiQ96E11
ProteomicsDBi76354
76355 [Q96E11-2]
76356 [Q96E11-3]
76357 [Q96E11-4]
76358 [Q96E11-5]
76359 [Q96E11-6]
76360 [Q96E11-7]
76361 [Q96E11-8]
TopDownProteomicsiQ96E11-3 [Q96E11-3]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
92399
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000297908; ENSP00000297908; ENSG00000148187 [Q96E11-8]
ENST00000344641; ENSP00000343867; ENSG00000148187 [Q96E11-1]
ENST00000373723; ENSP00000362828; ENSG00000148187 [Q96E11-2]
ENST00000373729; ENSP00000362834; ENSG00000148187 [Q96E11-3]
ENST00000394315; ENSP00000377850; ENSG00000148187 [Q96E11-2]
ENST00000467864; ENSP00000433288; ENSG00000148187 [Q96E11-4]
ENST00000470366; ENSP00000434807; ENSG00000148187 [Q96E11-6]
ENST00000489572; ENSP00000436360; ENSG00000148187 [Q96E11-6]
GeneIDi92399
KEGGihsa:92399
UCSCiuc010mwa.4 human [Q96E11-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
92399
DisGeNETi92399

GeneCards: human genes, protein and diseases

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GeneCardsi
MRRF
HGNCiHGNC:7234 MRRF
HPAiHPA047177
HPA049987
MIMi604602 gene
neXtProtiNX_Q96E11
OpenTargetsiENSG00000148187
PharmGKBiPA31029

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiKOG4759 Eukaryota
COG0233 LUCA
GeneTreeiENSGT00390000005084
InParanoidiQ96E11
KOiK02838
OMAiYYGAETP
OrthoDBi1590112at2759
PhylomeDBiQ96E11
TreeFamiTF323691

Enzyme and pathway databases

ReactomeiR-HSA-5419276 Mitochondrial translation termination

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
MRRF human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
92399

Protein Ontology

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PROi
PR:Q96E11

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000148187 Expressed in 168 organ(s), highest expression level in right testis
ExpressionAtlasiQ96E11 baseline and differential
GenevisibleiQ96E11 HS

Family and domain databases

InterProiView protein in InterPro
IPR002661 Ribosome_recyc_fac
IPR023584 Ribosome_recyc_fac_dom
IPR036191 RRF_sf
PANTHERiPTHR20982 PTHR20982, 1 hit
PfamiView protein in Pfam
PF01765 RRF, 1 hit
SUPFAMiSSF55194 SSF55194, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRRFM_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q96E11
Secondary accession number(s): A8K6D8
, A8K6Z4, B7Z4X5, B7Z6P7, Q5RKT1, Q5T7T0, Q5T7T1, Q5T7T2, Q5T7T3, Q5T7T4, Q5T7T5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: December 1, 2001
Last modified: June 5, 2019
This is version 141 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
  6. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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